Quinoxaline chemistry. Part 16. 4-Substituted anilino and 4-substituted phenoxymethyl pyrrolo[1,2-a]quinoxalines and N-[4-(pyrrolo[1,2-a]quinoxalin-4-yl)amino and hydroxymethyl]benzoyl glutamates. Synthesis and evaluation of in vitro biological activity

Farmaco

Volumn 58, Issue 9, 2003, Pages 639-650

  Alleca, Sergio ^a   Corona, Paola ^a   Loriga, Mario ^a   Paglietti, Giuseppe ^a   Loddo, Roberta ^b   Mascia, Valeria ^b   Busonera, Bernardetta ^b   La Colla, Paolo ^b  

^a UNIVERSITY OF SASSARI   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Antiproliferative agents; Potential antifolate agents; Pyrrolo 1,2 a quinoxalines

Indexed keywords

1 (2 AMINO 4 TRIFLUOROMETHYLPHENYL)PYRROLE; 2 CHLORO N [(5 TRIFLUOROMETHYL 2 PYRROL 1 YL)PHENYL]ACETAMIDE; 4 CHLOROMETHYL 7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALINE; DIETHYL N [4 (7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALIN 4 YL)AMINO]BENZOYL GLUTAMATE; DIETHYL N [4 (7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALIN 4 YL)HYDROXYMETHYL]BENZOYL GLUTAMATE; DIETHYL N [4 (PYRROLO[1,2 A]QUINOXALIN 4 YL)AMINO]BENZOYL GLUTAMATE; DIETHYL N [4 (PYRROLO[1,2 A]QUINOXALIN 4 YL)HYDROXYMETHYL]BENZOYL GLUTAMATE; FOLIC ACID ANTAGONIST; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; SOLID TUMOR;

EID: 0141566724     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(03)00101-0     Document Type: Article

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