Structure-activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 6, 2007, Pages 1663-1666

  Rong, Frank ^a   Chow, Suetying ^a   Yan, Shunqi ^a   Larson, Gary ^a   Hong, Zhi ^a   Wu, Jim ^a  

^a Drug Discovery   (United States)

Author keywords

HCV; Inhibitor; NS5B polymerase; Quinoxaline

Indexed keywords

QUINOXALINE DERIVATIVE;

ARTICLE; COMPUTER MODEL; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION;

COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; INDICATORS AND REAGENTS; MODELS, MOLECULAR; PROTEIN BINDING; QUINOXALINES; RNA REPLICASE; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 33847037381     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.103     Document Type: Article

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