Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells

Journal of Biomedical Optics

Volumn 13, Issue 5, 2008, Pages

  Wang, Hsing Wen ^a   Gukassyan, Vladimir ^a   Chen, Chien Tsun ^a   Wei, Yau Huei ^a   Guo, Han Wen ^a   Yu, Jia Sin ^a   Kao, Fu Jen ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

apoptosis detection, noninvasive optic probe; nicotinamide adenine dinucleotide intrinsic florescence; treatment outcome; two photon fluorescence lifetime imaging

Indexed keywords

AFTER-TREATMENT; AVERAGE LIFETIME; CANCER THERAPY; CLINICAL APPLICATION; DIRECT MONITORING; DYNAMIC CHANGES; FLUORESCENCE LIFETIMES; HELA CELL; INTRINSIC FLUORESCENCE; LIVE CELL; NADH FLUORESCENCE; NICOTINAMIDE ADENINE DINUCLEOTIDE INTRINSIC FLORESCENCE; NICOTINAMIDE ADENINE DINUCLEOTIDES; NONINVASIVE TOOLS; OSTEOSARCOMA; STAUROSPORINES; TREATMENT OUTCOME; TWO-PHOTON FLUORESCENCE LIFETIME; TWO-PHOTON FLUORESCENCE LIFETIME IMAGING;

AMIDES; CHROMOPHORES; FLUORESCENCE; HYDROGEN PEROXIDE; OPTIMIZATION; PHOTONS; TISSUE;

CELL DEATH;

NICOTINAMIDE ADENINE DINUCLEOTIDE;

APOPTOSIS; ARTICLE; COMPARATIVE STUDY; HELA CELL; HUMAN; METABOLISM; METHODOLOGY; NECROSIS; OSTEOSARCOMA; PATHOLOGY; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECTROFLUOROMETRY; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; HELA CELLS; HUMANS; NAD; NECROSIS; OSTEOSARCOMA; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

EID: 60849102190     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2975831     Document Type: Article

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