Fluorescence image-guided brain tumour resection with adjuvant metronomic photodynamic therapy: Pre-clinical model and technology development

Photochemical and Photobiological Sciences

Volumn 4, Issue 5, 2005, Pages 438-442

  Bogaards, Arjen ^a   Varma, Abhay ^c   Zhang, Kai ^b   Zach, David ^b   Bisland, Stuart K ^a   Moriyama, Eduardo H ^a   Lilge, Lothar ^a   Muller, Paul J ^c   Wilson, Brian C ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CANCER; CANCER INHIBITION; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; FLUORESCENCE; HISTOPATHOLOGY; IMAGING SYSTEM; LIGHT EMITTING DIODE; MICROSCOPE; NICK END LABELING; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RABBIT; SURGICAL TECHNIQUE;

ORYCTOLAGUS CUNICULUS;

EID: 19644381524     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/b414829k     Document Type: Article

References (24)

1. S. A. Friesen G. O. Hjortland S. J. Madsen H. Hirschberg O. Engebraten J. M. Nesland Q. Peng 5-Aminolevulinic acid–based photodynamic detection and therapy of brain tumors (review) Int. J. Oncol. 2002 21 577-582.
2. H. Kostron A. Obwegeser R. Jakober Photodynamic therapy in neurosurgery: a review J. Photochem. Photobiol. B: Biol. 1996 36 157-168.
3. K. M. Hebeda A. E. Saarnak M. Olivo H. J. Sterenborg J. G. Wolbers 5-Aminolevulinic acid induced endogenous porphyrin fluorescence in 9L and C6 brain tumours and in the normal rat brain Acta. Neurochir. 1998 140 503-512.
4. B. Olzowy C. S. Hundt S. Stocker K. Bise H. J. Reulen W. Stummer Photoirradiation therapy of experimental malignant glioma with 5-aminolevulinic acid J. Neurosurg. 2002 97 970-976.
5. W. Stummer S. R. Ennis A. L. Betz R. F. Keep In vitro and in vivo porphyrin accumulation by C6 glioma cells after exposure to 5-aminolevulinic acid Cereb. Blood Flow Metab. 1999 19 79-86.
6. L. Lilge M. C. Olivo S. W. Schatz J. A. MaGuire M. S. Patterson B. C. Wilson The sensitivity of normal brain and intracranially implanted VX2 tumour to interstitial photodynamic therapy Br. J. Cancer 1996 73 332-343.
7. L. Lilge B. C. Wilson Photodynamic therapy of intracranial tissues: a preclinical comparative study of four different photosensitizers J. Clin. Laser Med. Surg. 1998 16 81-91.
8. J. Moan L. W. Ma A. Juzeniene V. Iani P. Juzenas F. Apricena Q. Peng Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters Int. J. Cancer 2003 103 132-135.
9. S. R. Ennis A. Novotny J. Xiang P. Shakui T. Masada W. Stummer D. E. Smith R. F. Keep Transport of 5-aminolevulinic acid between blood and brain Brain Res. 2003 959 226-234.
10. M. Olivo B. C. Wilson Mapping ALA-induced PPIX fluorescence in normal brain and brain tumour using confocal fluorescence microscopy Int. J. Oncol. 2004 25 37-45.
11. M. J. Niedre A. J. Secord M. S. Patterson B. C. Wilson In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy Cancer Res. 2003 63 7986-7994.
12. A. Bogaards A. Varma S. P. Collens A. Lin A. Giles V. X. D. Yang J. M. Bilbao L. D. Lilge P. J. Muller B. C. Wilson Increased brain tumor resection using fluorescence guidance in a preclinical model Lasers Surg. Med. 2004 35 181-190.
13. W. Stummer H. Stepp G. Moller A. Ehrhardt M. Leonhard H. J. Reulen Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue Acta Neurochir. 1998 140 995-1000.
14. P. J. Muller B. C. Wilson Photodynamic therapy of malignant primary brain tumours: Clinical effects, post-operative ICP, and light penetration of the brain Photochem. Photobiol. 1987 46 929-935.
15. L. Lilge M. Portnoy B. C. Wilson Apoptosis induced in vivo by photodynamic therapy in normal brain and intracranial tumour tissue Br. J. Cancer 2000 83 1110-1117.
16. B. C. Wilson S. K. Bisland A. Bogaards A. Lin E. H. Moriyama K. Zhang L. D. Lilge Metronomic photodynamic therapy (mPDT): concepts and technical feasibility in brain tumor Proc. SPIE 2003 4952 23-31.
17. S. K. Bisland L. Lilge A. Lin R. Rusnov A. Bogaards B. C. Wilson Metronomic Photodynamic Therapy as a New Paradigm for Photodynamic Therapy: Rationale and Preclinical Evaluation of Technical Feasibility for Treating Malignant Brain Tumors Photochem. Photobiol. 2004 80 22-30.
18. A. Bogaards A. Varma E. H. Moriyama A. Lin A. Giles S. K. Bisland L. D. Lilge J. M. Bilbao P. J. Muller B. C. Wilson Fluorescence-guided resection of intracranial VX2 tumor in a preclinical model using 5-aminolevulinic acid (ALA): preliminary results Proc. SPIE 2003 4952 91-96.
19. A. Bogaards, A. Varma, A. Lin, A. Giles, S. K. Bisland, L. Lilge, J. M. Bilbao, P. J. Muller, and B. C. Wilson, Preclinical feasibility of fluorescence-guided tumor resection followed by metronomic photodynamic therapy (mPDT) using 5-aminolevulinic acid induced protoporphyrin IX: Preliminary results, SPIE Photonics North, abstract, 2003.
20. L. D. Lilge K. Menzies S. K. Bisland A. Lin B. C. Wilson PDT-induced apoptosis: investigations using two malignant brain tumor models Proc. SPIE 2002 4612 136-142.
21. Z. Darzynkiewics X. Li J. Gong Discrimination of cells dying by apoptosis Methods Cell Biol. 1994 41 15-38.
22. K. E. Wallner J. H. Galicich G. Krol E. Arbit M. G. Malkin S. F. Wallner Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma. Evidence that inhibition of erythropoiesis is important in the anemia of chronic renal failure Int. J. Rad. Oncol., Biol., Phys. 1989 16 1405-1409.
23. W. R. Shapiro L. S. Ashby E. A. Obbens Current therapy for brain tumors: back to the future brain tumors Arch. Neurol. 1999 56 429-432.
24. E. H. Moriyama S. K. Bisland L. Lilge B. C. Wilson Bioluminescence imaging of the response of rat gliosarcoma to ALA–PpIX mediated photodynamic therapy Photochem. Photobiol. 2004 80 242-249.