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Volumn 1, Issue 48, 2008, Pages

Ligand-dependent and-independent regulation of PPARγ and orphan nuclear receptors

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 60849087703     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.148pe52c     Document Type: Review
Times cited : (26)

References (35)
  • 2
    • 0038646966 scopus 로고    scopus 로고
    • Activation of nuclear receptors: A perspective from structural genomics
    • Y. Li, M. H. Lambert, H. E. Xu, Activation of nuclear receptors: A perspective from structural genomics. Structure 11, 741-746 (2003).
    • (2003) Structure , vol.11 , pp. 741-746
    • Li, Y.1    Lambert, M.H.2    Xu, H.E.3
  • 3
    • 0033617520 scopus 로고    scopus 로고
    • Orphan nuclear receptors: Shifting endocrinology into reverse
    • S. A. Kliewer, J. M. Lehmann, T. M. Willson, Orphan nuclear receptors: Shifting endocrinology into reverse. Science 284, 757-760 (1999).
    • (1999) Science , vol.284 , pp. 757-760
    • Kliewer, S.A.1    Lehmann, J.M.2    Willson, T.M.3
  • 4
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (ppar γ)
    • J. M. Lehmann, L. B. Moore, T. A. Smith-Oliver, W. O. Wilkison, T. M. Willson, S. A. Kliewer, An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J. Biol. Chem. 270, 30221-30229 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 30221-30229
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 5
    • 1942518840 scopus 로고    scopus 로고
    • Ppars and the complex journey to obesity
    • R. M. Evans, G. D. Barish, Y. X. Wang, PPARs and the complex journey to obesity. Nat. Med. 10, 355-361 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.X.3
  • 6
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARγ
    • M. Lehrke, M. A. Lazar, The many faces of PPARγ. Cell 123, 993-999 (2005).
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 7
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • J. N. Feige, L. Gelman, L. Michalik, B. Desvergne, W. Wahli, From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog. Lipid Res. 45, 120-159 (2006).
    • (2006) Prog. Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 8
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor
    • P. Tontonoz, E. Hu, B. M. Spiegelman, Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor. Cell 79, 1147-1156 (1994).
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 17
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator- activated receptors α and δ
    • B. M. Forman, J. Chen, R. M. Evans, Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator- activated receptors α and δ. Proc. Natl. Acad. Sci. U.S.A. 94, 4312-4317 (1997).
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 19
    • 54049100418 scopus 로고    scopus 로고
    • A functional peroxisome proliferator-activated receptor-γ ligandbinding domain is not required for adipogenesis
    • C. J. Walkey, B. M. Spiegelman, A functional peroxisome proliferator-activated receptor-γ ligandbinding domain is not required for adipogenesis. J. Biol. Chem. 283, 24290-24294 (2008).
    • (2008) J. Biol. Chem , vol.283 , pp. 24290-24294
    • Walkey, C.J.1    Spiegelman, B.M.2
  • 22
    • 49649094046 scopus 로고    scopus 로고
    • Structural and biochemical basis for the binding selectivity of peroxisome proliferatoractivated receptor γ to PGC-1
    • Y. Li, A. Kovach, K. Suino-Powell, D. Martynowski, H. E. Xu, Structural and biochemical basis for the binding selectivity of peroxisome proliferatoractivated receptor γ to PGC-1α. J. Biol. Chem. 283, 19132-19139 (2008).
    • (2008) J. Biol. Chem , vol.283 , pp. 19132-19139
    • Li, Y.1    Kovach, A.2    Suino-Powell, K.3    Martynowski, D.4    Xu, H.E.5
  • 23
    • 4143099405 scopus 로고    scopus 로고
    • Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3t3-l1 adipocytes
    • I. Tzameli, H. Fang, M. Ollero, H. Shi, J. K. Hamm, P. Kievit, A. N. Hollenberg, J. S. Flier, Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes. J. Biol. Chem. 279, 36093-36102 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 36093-36102
    • Tzameli, I.1    Fang, H.2    Ollero, M.3    Shi, H.4    Hamm, J.K.5    Kievit, P.6    Hollenberg, A.N.7    Flier, J.S.8
  • 24
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
    • D. S. Straus, C. K. Glass, Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms. Trends Immunol. 28, 551-558 (2007).
    • (2007) Trends Immunol , vol.28 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 25
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARγ
    • P. Tontonoz, B. M. Spiegelman, Fat and beyond: The diverse biology of PPARγ. Annu. Rev. Biochem. 77, 289-312 (2008).
    • (2008) Annu. Rev. Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 27
    • 0036257153 scopus 로고    scopus 로고
    • Differential gene regulation by PPARγ agonist and constitutively active pparγ2
    • Y. Li, M. A. Lazar, Differential gene regulation by PPARγ agonist and constitutively active PPARγ2. Mol. Endocrinol. 16, 1040-1048 (2002).
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1040-1048
    • Li, Y.1    Lazar, M.A.2
  • 29
    • 13944276441 scopus 로고    scopus 로고
    • Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor
    • Y. Li, M. Choi, G. Cavey, J. Daugherty, K. Suino, A. Kovach, N. C. Bingham, S. A. Kliewer, H. E. Xu, Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor- Mol. Cell 17, 491-502 (2005).
    • (2005) Mol. Cell , vol.17 , pp. 491-502
    • Li, Y.1    Choi, M.2    Cavey, G.3    Daugherty, J.4    Suino, K.5    Kovach, A.6    Bingham, N.C.7    Kliewer, S.A.8    Xu, H.E.9
  • 32
    • 21644456253 scopus 로고    scopus 로고
    • Activation of nur77 by selected 1, 1-bis(3′-indolyl)-1-(p- substituted phenyl)methanes induces apoptosis through nuclear pathways
    • S. Chintharlapalli, R. Burghardt, S. Papineni, S. Ramaiah, K. Yoon, S. Safe, Activation of Nur77 by selected 1, 1-Bis(3′-indolyl)-1-(p- substituted phenyl)methanes induces apoptosis through nuclear pathways. J. Biol. Chem. 280, 24903-24914 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 24903-24914
    • Chintharlapalli, R.B.S.1    Papineni, S.R.S.2    Yoon, S.S.K.3
  • 35
    • 84890095519 scopus 로고    scopus 로고
    • We thank D. Nadziejka for editing the manuscript. This work was supported in part by the Jay and Betty Van Andel Foundation (H.E.X.), U.S. National Institutes of Health grants DK071662 and DK066202 (H.E.X.) and HL089301 (H.E.X. and Y.L
    • We thank D. Nadziejka for editing the manuscript. This work was supported in part by the Jay and Betty Van Andel Foundation (H.E.X.), U.S. National Institutes of Health grants DK071662 and DK066202 (H.E.X.) and HL089301 (H.E.X. and Y.L.).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.