Realistic approach for full-scale bioethanol production from lignocellulose: A review

Journal of Scientific and Industrial Research

Volumn 67, Issue 11, 2008, Pages 874-884

  Tomas Pejo E ^a   Oliva, J M ^a   Ballesteros, M ^a  

^a CIEMAT   (Spain)

Author keywords

Bioethanol; Lignocellulosic materials; Xylose

Indexed keywords

CELLULOSE; ETHANOL; MICROORGANISMS; SUBSTRATES;

CELLULOSE; ETHANOL; FERMENTATION; LITERATURE REVIEW; OPTIMIZATION; SUBSTRATE;

EID: 60649105383     PISSN: 00224456     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (129)

1. Aristidou A & Penttila M, Metabolic engineering application to renewable resource utilization, Curr Opin Biolechnol, 11 (2000) 187-198.
2. Sánchez O J & Cardona C A, Trends in biotechnological production of fuel ethanol from different feedstocks, Biores Technol, 99 (2008) 5270-5295.
3. Cazetta M L, Celligoi M A P C, Buzato J B & Scarmino I S, Fermentation of molasses by Zymomonas mobilis: Effects of temperature and sugar concentration on ethanol production, Biores Technol, 98 (2007) 2824-2828.
4. Limtong S, Sringiew C & Yongmanitchai W, Production of fuel ethanol at high temperature from sugar cane juice by a newly isolated Kluyveromyces marxianus, Biores Technol, 98 (2007) 3367-3374.
5. Devantier R, Pedersen S & Olsson L, Characterization of very high gravity ethanol fermentation of corn mash. Effect of glucoamylase dosage, pre-saccharification and yeast strain, Appl Biochem Biotechnol, 68 (2005) 622-629.
6. Bothast R J & Schlicher M A, Biotechnological process for conversion of corn into ethanol, Appl Biochem Biotechnol, 67 (2005) 19-25.
7. Wang S, Ingledew W M, Thomas K C, Sosulski K & Sosulski F W, Optimization of fermentation temperature and mash specific gravity for fuel alcohol production, Cereal Chem, 76 (1999) 82-86.
8. Blanco M I & Azqueta D, Can the environmental benefits of biomass support agriculture? The case of cereals for electricity and bioethanol production in Northern Spain, Energy Policy, 36 (2008) 357-366.
9. Rosenberger A, Identification of top-performing cereal cultivars for grain-to-ethanol operations, Zuckerindustrie 130 (2005) 697-701.
10. Aggarwal N K, Nigam P, Singh D & Yadav B S, Process optimization for the production of sugar for the bioethanoI industry from Tapioca, a non-conventional source of starch, World J Microbiol Biotechnol, 17 (2001) 783-787.
11. Wang S, Thomas K C, Sosulski K, Ingledew W M & Sosulski F W, Grain pearling and very high gravity (VHG) fermentation technologies for fuel alcohol production from rye and triticale, Process Biochem, 34 (1999) 421-428.
12. Laopaiboon L, Thanonkeo P, Jaisil P & Laopaiboon P, Ethanol production from sweet sorghum juice in batch and fed-batch fermentations by Saccharomyces cerevisiae, World J Microbiol Biotechnol, 23 (2007) 1497-1501.
13. Zhan X, Wang D, Tuinstra M R, Bean S, Seib P A & Sun X S, Ethanol and lactic acid production as affected by sorghum genotype and location, Ind Crops Prod, 18 (2003) 245-255.
14. Hahn-Hägerdal B, Galbe M, Gorwa-Grauslund M F, Liden G, Zacchi G, Bio-ethanol - the fuel of tomorrow from the residues of today, Trends Biotechnol, 24 (2006) 549-556.
15. Kim S & Dale B E, Global potential bioethanol production from wasted crops and crop residues, Biomass Bioenergy, 26 (2004) 361-375.
16. Lynd L R, Overview and evaluation of fuel ethanol from cellulosic biomas: technology, economics, the environment, and policy, Annu Rev Energy Env, 21 (1996) 403-465.
17. Solomon B D, Barnes J R & Halvorsen K E, Grain and cellulosic ethanol: History, economics, and energy policy, Biomass Bioenergy 31 (2007) 416-425.
18. Demirbas A, Progress and recent trends in biofuels, Prog Energy Combust Sci, 33 (2007) 1-18.
19. Wyman C E, Biomass ethanol: Technical progress, opportunities, and commercial challenges, Annu Rev Energy Env, 24 (1999) 199-226.
20. Berndes G, Azar C, Kaberger T & Abrahamson D, The feasibility of large-scale lignocellulose-based bioenergy production, Biomass Bioenergy, 20 (2001) 371-383.
21. Kalogo Y, Habibi S, Maclean H L & Joshi S V, Environmental implications of municipal solid waste-derived ethanol, Environ Sci Technol, 41, (2007) 35-41.
22. Broder J D, Harris RA & Ranney JT, Using MSW and industrial residues as ethanol feedstocks, Biocycle, 42 (2001) 23-26.
23. Ballesteros M, Oliva J M, Manzanares P, Negro M J & Ballesteros I, Ethanol production from paper material using a simultaneous saccharification and fermentation system in a fed-batch basis, World J Microbiol Biotechnol, 18 (2002) 559-561.
24. Bamaga O A, Verma M L & Thakur T C, Assessment of cereal straw availability in combine harvested fields and its recovery by baling, AMA Agricultural Mechanization in Asia, Africa and Latin America, 34 (2003) 53-58.
25. FAOSTAT: Food and Agricultural Organization (FAO): http://apps .fao.org/(2007)
26. Ruiz E, Cara C, Ballesteros M, Manzanares P, Ballesteros I & Castro E, Ethanol production from pretreated olive tree wood and sunflower stalks by an SSF process, Appl Biochem Biotechnol, 130 (2006) 631-643.
27. Berndes G, Hoogwijk M & Van Den Broek R, The contribution of biomass in the future global energy supply: a review of 17 studies, Biomass Bioenergy, 25 (2003) 1-28.
28. Negro M J, Manzanares P, Ballesteros I, Oliva JM, Cabañas A & Ballesteros M, Hydrothermal pretreatment conditions to enhance ethanol production from poplar biomass, Appl Biochem Biotechnol, 105 (2003) 87-100.
29. Wyman C E, Handbook on Bioethanol: Production and Utilization (Taylor & Francis, Washington) 1996, 105-118.
30. 4 impregnation for ethanol production, Biomass Bioenergy, 24 (2003) 475-486.
31. Sassner P, Galbe M & Zacchi G, Bioethanol production based on simultaneous saccharification and fermentation of steam- pretreated Salix at high dry-matter content, Enzyme Microb Technol, 39 (2006) 756-762.
32. Hayn M, Steiner W, Klinger R, Steinmüller H, Sinner M, Esterbauer H, Basic research and pilot studies on the enzymatic conversion of lignocellulosics, in Bioconversion of Forest and Agricultural Plant Residues (Saddler JN CAB International, Wallingford) 1993, 33-72.
33. 2-impregnated corn stover for fuel ethanol production, Appl Biochem Biotechnol, 121 (2005) 1055-1067.
34. Ballesteros I, Negro M, Oliva J M, Cabahas A, Manzanares P & Ballesteros M, Ethanol production from steam-explosion pretreated wheat straw, Appl Biochem Biotechnol, 130 (2006) 496-508.
35. García-Aparicio M, Ballesteros I, González A, Oliva J M, Ballesteros M & Negro M J, Effect of inhibitors released during steam-explosion pretreatment of barley straw on enzymatic hydrolysis, Appl Biochem Biotechnol, 129 (2006) 278-288.
36. Cara C, Ruiz E, Ballesteros M, Manzanares P, Negro M J & Castro E, Production of fuel ethanol from steam-explosion pretreated olive tree pruning, Fuel, 87 (2007) 692-700.
37. Lynd LR, Weimer P J, Van Zyl W H & Pretorius I S, Microbial cellulose utilization: Fundamentals and biotechnology, Microbiol Mol Biol R, 66 (2002) 506-577.
38. Fengel D & Wegener G, Wood, Chemistry, Ultrastructure and Reactions (Walter de Gruyter, Berlin-New York) 1989, 66-100.
39. Zhang H Y & Lynd L R, Toward an aggregated understanding of enzymatic hydrolysis of cellulose: noncomplexed cellulase systems, Biotechnol Bioeng, 88 (2004) 797-779.
40. Dahlman O, Jacobs A & Berg J, Molecular properties of hemicelluloses located in the surface and inner layers of hardwood and softwood pulps, Cellulose, 10 (2003) 325-334.
41. Howard R L, Abotsi E, Van Rensburg E L J & Howard S, Lignocellulose biotechnology: Issues of bioconversion and enzyme production. Afr J Biotechnol, 2 (2003) 602-619.
42. Higuchi T, Lignin Biochemistry: Biosynthesis and Biodegradation, Wood Sci Technol, 24 (1990) 23-63.
43. Evers A D, Blakeney A B & O'Brien L, Cereal structure and composition, Aust J Agric Res, 50 (1999) 629-650.
44. Pan X, Zhang X, Gregg D J & Saddler J N, Enhanced enzymatic hydrolysis of steam-exploded Douglas fir wood by alkali- oxygen post-treatment, Appl Biochem Biotechnol, 115 (2004) 1103-1114.
45. Berlin A, Gilkes N, Kilburnn D, Bura R, Markov A, Okunev O, Gusarov A, Maximenko V, Gregg D & Saddler J N, Evaluation of novel fungal cellulase prepration for ability to hydrolyze softwood substrate-evidence of the role of accesory enzymes, Enzyme Microb Technol, 37 (2005) 175-184.
46. Mosier N, Wyman C E, Dale B D, Elander R T, Lee Y Y, Holtzapple M & Ladisch C M, Features of promising technologies for pretreatment of lignocellulosic biomass, Biores Technol, 46 (2005) 673-686.
47. Curreli N, Agelli M, Pisu B, Rescigno A, Sanjust E & Rinaldi A, Complete and efficient enzymic hydrolysis of pretreated wheat straw, Process Biochem, 37 (2002) 937-941.
48. Gharpuray M M, Lee Y H & Fan L T, Structural modification of lignocellulosics by pretreatments to enhance enzymatic hydrolysis, Biotechnol Bioeng, 25 (1983) 157-172.
49. Wyman C E, Dale B E, Elander R T, Holtzapple M, Ladisch M R, Lee Y Y, Coordinated development of leading biomass pretreatment technologies, Biores Technol, 96 (2005) 1959-1966.
50. Van Walsum G P, Allen S G, Spenser M J, Laser M S, Antal M J & Lynd L R, Conversion of lignocelulosics pretreated with liquid hot water to ethanol, Appl Biochem Biotechnol, 57-58 (1996) 157-170.
51. Sun Y & Cheng J, Hydrolysis of lignocellulosic materials for ethanol production: a review, Biores Technol, 83 (2002) 1-11.
52. Tengerdy RP & Szakacs G, Bioconversion of lignocellulose in solid substrate fermentation, Biochem Eng J, 13 (2003) 169-179.
53. Cardona C A & Sánchez O J, Fuel ethanol production: Process design trends and integration opportunities, Biores Technol, 98 (2007) 2415-2457.
54. Esteghlalian A, Hashimoto A G, Fenske J J & Penner M H, Modeling and optimization of the dilute-sulfuric-acid pretreatment of corn stover, poplar and switchgrass, Biores Technol, 59 (1997) 129-136.
55. Ballesteros M, Negro M J, Manzanares P, Ballesteros I, Sáez F & Oliva J M, Fractionation of Cynara cardunculus (cardoon) biomass by dilute-acid pretreatment, Appl Biochem Biotechnol, 136-140 (2007) 239-252.
56. Scott D S, Paterson L, Piskorz J & Radlein D, Pretreatment of poplar wood for fast pyrolysis: rate of cation removal, J Anal Appl Pyrolysis, 57 (2001) 169-176.
57. Brownell H H & Saddler J N, Steam pretreatment of lignocellulosic material for enhanced enzymatic hydrolysis, Biotechnol Bioeng, 29 (1987) 228-235.
58. Avellar B K & Glasser W G, Steam-assisted biomass fractionation. I Process considerations and economic evaluation, Biomass Bioenergy, 14 (1998) 205-218.
59. Higuchi T, Steam explosion of wood-Biomass Handbook (Hall C.W. KO) 1989, 470-474.
60. Pérez JA, González A, Oliva J M, Ballesteros I & Manzanares P, Effect of process variables on liquid hot water pretreatment of wheat straw for bioconversion to fuel-ethanol in a batch reactor, J Chem Technol Biotechnol, 82 (2007) 929-939.
61. Ogier J C, Ballerini D, Leygue J P, Rigal L & Pourquié J, Production d'éthanol à partir de biomasse lignocellulosique, Oil Gas Sci Technol, 54 (1999) 67-94.
62. Teymouri F, Laureano-Perez L, Alizadeh H & Date B E, Optimization of the ammonia fiber explosion (AFEX) treatment parameters for enzymatic hydrolysis of corn stover, Biores Technol, 96 (2005) 2014-2018.
63. Himmel M E, Adney W S, Baker J O, Elander R, McMillan J D, Nieves RA, Sheehan J J, Thomas S R, Vinzant T B & Zhang M, Advanced bioethanol production technologies: A Perspective, ACS Symp Ser, 666 (1997) 1-45.
64. Gregg D & Saddler J N, Bioconversion of lignocellulosic residue to ethanol: Process flowsheet development, Biomass Bioenergy, 9 (1995) 287-302.
65. Schell DJ, Riley CJ, Dowe N, Farmer J, Ibsen K N, Ruth M F, Toon S T & Lumpkin R E, A bioethanol process development unit: initial operating experiences and results with a corn fiber feedstock, Biores Technol, 91 (2004) 179-188.
66. Schell D J & Duff B, Review of pilot plant programs for bioethanol conversion, in Handbook on Bioethanol: Production and Utilization (Taylor & Francis, Washington) 1996, 381-384.
67. Alfani A, Gallifuoco F, Saporosi A, Spera A & Cantarella M, Comparison of SHF and SSF process for the bioconversion of steam-exploded wheat straw, J Ind Microb Biotechnol, 25 (2000) 184-192.
68. Palonen H, Role of lignin in the enzymatic hydrolysis of lignocellulose, Ph D Thesis Dissertation, Helsinki University of Technology, Finland, 2004.
69. Oliva J M, Saez F, Ballesteros I, Gonzáleź A, Negro M J, Manzanares P & Ballesteros M, Effect of lignocellulosic degradation compounds from steam explosion pretreatment on ethanol fermentation by thermotolerant yeast Kluyveromyces marxianus, Appl Biochem Biotechnol, 105 (2003) 141-154.
70. Ramos L P, Breuil C, Kushner D J & Saddler J N, Steam pretreatment conditions for effective enzymatic hydrolysis and recovery yields of Eucalyptus viminalis wood chips, Holzforschung, 46 (1992) 149-154.
71. Fernández-Bolaños J, Rodríguez G, Rodríguez R, Heredia A, Guillen R & Jiménez A, Production in large quantities of highly purified hydroxytyrosol from liquid-solid waste of two-phase olive oil processing or "Alperujo", J Agric Food Chem, 50 (2002) 6804-6811.
72. Cara C, Ruiz E, Ballesteros I, Negro M J & Castro E, Enhanced enzymatic hydrolysis of olive tree wood by steam explosion and alkaline peroxide delignification, Process Biochem, 41 (2006) 423-429.
73. Varga E, Reczey K & Zacchi G, Optimization of steam pretreatment of corn stover to enhance enzymatic digestibility, Appl Biochem Biotechnol, 113-116 (2004) 509-523.
74. Öhgren K, Rudolf A, Galbe M & Zacchi G, Fuel ethanol production from steam-pretreated corn stover using SSF at higher dry matter content. Biomass Bioenergy, 30 (2006) 863-869.
75. Glasser W G & Wright R S, Steam-assisted biomass fractionation. II Fractionation behaviour of various biomass resources, Biomass Bioenergy, 14 (1998) 219-235.
76. Hamelinck C, Van Hooijdonk G & Faaij A, Ethanol from lignocellulosic biomass: techno-economic performance in short-, middle- and long-term, Biomass Bioenergy, 28 (2004) 384-410.
77. Clark T A & Mackie K L, Steam explosion of the softwood Pinus radiata with sulphur dioxide addition I. Process optimization, J Wood Chem Technol, 7 (1987) 373-403.
78. Ballesteros I, Oliva J M, Negro M J, Manzanares P & Ballesteros M, Enzymic hydrolysis of steam exploded herbaceous agricultural waste ( Brassica carinata) at different particle sizes, Process Biochem, 38 (2002) 187-192.
79. Linde M, Galbe M & Zacchi G, Simultaneous saccharification and fermentation of steam-preteated barley straw at low enzyme loading and low yeast concentration, Enzyme Microb Technol, 40 (2007) 1100-1107.
80. Stenberg K, Tengborg C, Galbe M, Zacchi G, Palmqvist E & Hahn-Hägerdal B, Recycling of process streams in ethanol production from softwoods based on enzymatic hydrolysis, Appl Biochem Biotechnol, 70-72 (1998) 697-708.
81. 4 impregnation of softwood prior to steam pretreatment on ethanol production, Appl Biochem Biotechnol, 70-72 (1998) 3-15.
82. 2 impregnation for ethanol production. Appl Biochem Biotechnol, 99-100 (2002) 5-21.
83. Galbe M & Zacchi G, A review of the production of ethanol from softwood, Appl Biochem Biotechnol, 59 (2002) 609-617.
84. Zaldivar J, Nielsen J & Olsson L, Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration, Appl Microbil Biotechnol, 56 (2001) 17-34.
85. Palmqvist E & Hahn-Hägerdal B, Fermentation of lignocellulosic hydrolysates II: inhibitors and mechanism of inhibition, Biores Technol, 74 (2000) 25-33.
86. Almeida J R M, Modig T, Petersson A, Hahn-Hägerdal B, Liden G & Gorwa-Grauslund MF, Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae, J Chem Technol Biotechnol, 82 (2007) 340-349.
87. Liu ZL, Slininger P J & Gorsich S W, Enhanced biotransformation of furfural and hydrolxymethylfurfural by newly developed ethanologenic yeast strains, Appl Biochem Biotechnol, 121-124 (2005) 451-460.
88. Tomás-Pejó E, Oliva J M, Ballesteros M & Olsson L, Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains, Biotechnol Bioeng, 100 (2008) 1122-1131.
89. Wingren A, Galbe M & Zacchi G, Techno-economic evaluation of producing ethanol from softwood: comparison of SSF and SHF and identification of bottlenecks, Biotechnol Progr, 19 (2003) 1109-1117.
90. Jorgensen H, Kristensen J B & Felby C, Enzymatic conversion of lignocellulose into fermentable sugars: challenges and opportunities. Biofuels, Bioprod Biorefin, 1 (2007) 119-134.
91. Ballesteros I, Oliva J M, Ballesteros M & Carrasco J, Optimization of the simultaneous saccharification and fermentation process using thermotolerant yeasts, Appl Biochem Biotechnol, 39-40 (1993) 201-211.
92. Banat I M, Nigam P, Singh D, Marchant R & McHale A P, Review: Ethanol production at elevated temperatures and alcohol concentrations: Part I - Yeast in general. World J Microbiol Biotechnol, 13 (1998) 809-829.
93. Palmqvist E, Hahn-Hägerdal B, Szengyel Z, Zacchi G & Rèczey K, Simultaneous detoxification and enzyme production of hemicellulose hydrolysates obtained after steam pretreatment, Enzyme Microb Technol 20 (1997) 286-293.
94. Klinke H B, Thomsen A B & Ahring B K, Inhibition of ethanol- producing yeast and bacteria by degradation products produced during pre-treatment of biomass, Appl Biochem Biotechnol, 66 (2004) 10-26.
95. Hahn-Hägerdal B, Jeppsson H & Prior B A, Biochemistry and physiology of xylose fermentation by yeast, Enzyme Microb Technol, 16 (1994) 933-943.
96. Ingram L O, Gomez P F, Moniruzzaman M, Wood B E, Yomano L P & York S W, Metabolic engineering of bacteria for ethanol production, Biotechnol Bioeng, 58 (1998) 205-214.
97. Dien B S, Cotta M A & Jeffries T W, Bacteria engineered for fuel ethanol production: Current status, Appl Biochem Biotechnol, 63 (2003) 258-266.
98. Wang Z, Chen M, Xu Y, Li S, Lu W, Ping S, Zhang W & Lin M, An ethanol-tolerant recombinant Escherichia coli expressing Zymomonas mobilis pdc and adhB genes for enhanced ethanol production from xylose, Biotechnol Lett, 30 (2008) 657-663.
99. Tao H, Gonzalez R, Martinez A, Rodriguez M, Ingram L O, Preston J F & Shanmugam K T, Engineering a homo-ethanol pathway in Escherichia coli: Increased glycolytic flux and levels of expression of glycolytic genes during xylose fermentation, J Bacteriol, 183 (2001) 2979-2988.
100. Doran-Peterson J, Cook D M & Brandon S K, Microbial conversion of sugars from plant biomass to lactic acid or ethanol, Plant J, 54 (2008) 582-592.
101. Kim T H, Taylor F & Hicks K B, Bioethanol production from barley hull using SAA (soaking in aqueous ammonia) pretreatment, Biores Technol, 99 (2008) 5694-5702.
102. Mishima D, Kuniki M, Sei K, Soda S, Ike M & Fujita M, Ethanol production from candidate energy crops: Water hyacinth (Eichhornia crassipes) and water lettuce (Pistia stratiotes L.), Biores Technol, 99 (2008) 2495-2500.
103. Grohmann K, Baldwin E A, Buslig B S & Ingram L O, Fermentation of galacturonic acid and other sugars in orange peel hydrolysates by the ethanologenic strain of Escherichia coli, Biotechnol Lett, 16 (1994) 281-286.
104. Dien B S, Hespell R B, Ingram L O & Bothast R J, Conversion of corn milling fibrous co-products into ethanol by recombinant Escherichia coli strains K011 and SL4, World J Microbiol Biotechnol, 13 (1997) 619-625.
105. Okuda N, Ninomiya K, Takao M, Katakura Y & Shioya S, Microaeration enhances productivity of bioethanol from hydrolysate of waste house wood using ethanologenic Escherichia coli KO11, J Biosci Bioeng, 103 (2007) 350-357.
106. Brandon S K, Eiteman M A, Patel K, Richbourg M M, Miller D J, Anderson W F & Peterson J D, Hydrolysis of Tifton 85 bermudagrass in a pressurized batch hot water reactor, J Chem Technol Biotechnol, 83 (2008) 505-512.
107. Zhang M, Eddy C, Deanda K, Finkelstein M & Picataggio S, Metabolic engineering of a pentose metabolism pathway in ethanologenic Zymomonas mobilis, Science, 267 (1995) 240-243.
108. Patle S & Lal B, Investigation of the potential of agro-industrial material as low cost substrate for ethanol production by using Candida tropicalis and Zymomonas mobilis, Biomass Bioenergy, 32 (2008) 596-602.
109. Mohagheghi A, Evans K, Chou Y C & Zhang M, Cofermentation of glucose, xylose, and arabinose by genomic dna-integrated xylose/arabinose fermenting strain of Zymomonas mobilis AX101, Appl Biochem Biotechnol, 98-100 (2002) 885-898.
110. Golias H, Dumsday G J, Stanley G A, Pamment N B, Evaluation of a recombinant Klebsiella oxytoca strain for ethanol production from cellulose by simultaneous saccharification and fermentation: comparison with native cellobiose-utilising yeast strains and performance in co-culture with thermotolerant yeast and Zymomonas mobilis, J Biotechnol, 96 (2002) 155-168.
111. Wood B E & Ingram L O, Ethanol production from cellobiose, amorphous cellulose, and crystalline cellulose by recombinant, Klebsiella oxytoca containing chromosomally integrated Zymomonas mobilis genes for ethanol production and plasmids expressing thermostable cellulase genes from Clostridium thermocellum, Appl Environ Microbiol, 58 (1992) 2103-2110.
112. Moniruzzaman M, Dien B S, Ferrer B, Hespell R B, Dale B E, Ingram L O & Bothast R J, Ethanol production from AFEX pretreated corn fiber by recombinant bacteria, Biotechnol Lett, 18 (1996) 985-990.
113. Doran J B, Cripe J, Sutton M & Foster B, Fermentations of pectin-rich biomass with recombinant bacteria to produce fuel ethanol, Appl Biochem Biotechnol, 84-86 (2000) 141-152.
114. Olsson L & Hahn-Hägerdal B, Fermentative performance of bacteria and yeast in lignocellulose hydrolysates, Process Biochem, 28 (1993) 249-257.
115. Karhumaa K, Sanchez R G, Hahn-Hägerdal B & Gorwa-Grauslund M F, Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae, Microb Cell Fact, 6 (2007) art.no.5.
116. Chandrakant P & Bisaria V S, Simultaneous bioconversion of glucose and xylose to ethanol of Saccharomyces cerevisiae in the presence of xylose isomerase, Appl Biochem Biotechnol, 53 (2000) 301-309.
117. Eliansson A, Christensson C, Wahlbom F & Hahn-Hägerdal B, Anaerobic xylose fermentation by recombinant Saccharomyces cerevisiae carrying XYL1, XYL2 and XKS1 in mineral medium chemostat cultures, Appl Environ Microbiol, 66 (2000) 3381-3386.
118. Zaldivar J, Borges A, Johansson B, Smits H P, Villas-Boas S G, Nielsen J & Olsson L, Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae, Appl Biochem Biotechnol, 59 (2002) 436-442.
119. Jeppsson M, Johansson B, Hahn-Hägerdal B & Gorwa-Grauslund M F, Reduced oxidative pentose phosphate pathway flux in recombinant xylose-utilizing Saccharomyces cerevisiae strains improves the ethanol yield from xylose, Appl Environ Microbiol, 68 (2002) 1604-1609.
120. Martin C, Galbe M, Wahlbom C F, Hahn-Hägerdal B & Jonsson L J, Ethanol production from enzymatic hydrolysates of sugarcane bagasse using recombinant xylose-utilising Saccharomyces cerevisiae, Enzyme Microb Technol, 31 (2002) 274-282.
121. Öhgren K, Bengtsson O, Gorwa-Grauslund M F, Galbe M, Hahn-Hägerdal B & Zacchi G, Simultaneous saccharification and co-fermentation of glucose and xylose in steam-pretreated corn stover at high fiber content with Saccharomyces cerevisiae TMB3400, J Biotechnol, 126 (2006) 488-498.
122. Olofsson K, Rudolf A & Liden G, Designing simultaneous saccharification and fermentation for improved xylose conversion by a recombinant strain of Saccharomyces cerevisiae, J Biotechnol, 134 (2008) 112-120.
123. Sonderegger M, Jeppsson H, Larsson C, Gorwa-Grauslund M F, Boles E, Olsson L, Spencer-Martins I, Hahn-Hägerdal B & Sauer V, Fermentation performance of engineered and evolve xylose-fermenting Saccharomyces cerevisiae strains, Biotechnol Bioeng, 87 (2004) 90-98.
124. Johansson B, Christensson C, Hobley T & Hahn-Hägerdal B, Xylulokinase overexpression in two strains of Saccharomyces cerevisiae also expressing xylose reductase and xylitol dehydrogenase and its effect on fermentation of xylose and lignocellulosic hydrolysate, Appl Environ Microbiol, 67 (2001) 4249-4255.
125. Meinander N Q & Hahn-Hägerdal B, Influence of co-substrate concentration on xylose conversion by recombinant, XL1- expressing Saccharomyces cerevisiae: a comparison of different sugars and ethanol as co-substrates. Appl Environ Microbiol, 63 (1997) 1959-1964.
126. Chu B C H & Lee H, Genetic improvement of Saccharomyces cerevisiae for xylose fermentation, Biotechnol Adv, 25 (2007) 425-441.
127. Hamacher T, Becker J, Gardonyi M, Hahn-Hägerdal B & Boles E, Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization, Microbiology, 148 (2002) 2783-2788.
128. Shi N Q & Jeffries T W, Anaerobic growth and improved fermentation of Pichia stipitis bearing a URA1 gene from Saccharomyces cerevisiae, Appl Biochem Biotechnol, 50 (1998) 339-345.
129. Shi N Q, Davis B, Sherman F, Cruz J & Jeffries T W, Disruption of the cytochrome c gene in xylose-utilizing yeast Pichia stipitis leads to higher ethanol production, Yeast, 15 (1999) 1021-1030.