Characterisation of the advanced glycation endproduct receptor complex in the retinal pigment epithelium

British Journal of Ophthalmology

Volumn 89, Issue 1, 2005, Pages 107-112

  McFarlane, S ^a   Glenn, J V ^a   Lichanska, A M ^a   Simpson, D A C ^a   Stitt, A W ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ALBUMIN; BINDING PROTEIN; GALECTIN 3; MESSENGER RNA;

AGING; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COW; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RETINA MACULA AGE RELATED DEGENERATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CATTLE; CELL LINE; CULTURE MEDIA; GALECTIN 3; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; IMMUNOHISTOCHEMISTRY; PIGMENT EPITHELIUM OF EYE; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOLUBILITY; TRANSFECTION; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 11144267118     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2004.045914     Document Type: Article

References (32)

1. Boulton M, Dayhaw-Barker P. The role of the retinal pigment epithelium: topographical variation and ageing changes. Eye 2001;15:384-9.
2. Hageman GS, Luthert PJ, Victor Chong NH, et al. An integrated hypothesis that considers drusen as biomarkers or immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 2001;20:705-32.
3. Baynes JW. The role of AGEs in aging: causation or correlation. Exp Gerontol 2001;36:1527-37.
4. Thornalley PJ. Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs. Cell Mol Biol (Noisyle-grand) 1998;44:1013-23.
5. Schmidt AM, Yan SD, Yan SF, et al. The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta 2000;1498:99-111.
6. Li YM, Mitsuhashi T, Wojciechowicz D, et al. Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins. Proc Natl Acad Sci U S A 1996;93:11047-52.
7. Vlassara H, Li YM, Imani F, et al. Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex. Mol Med 1995;1:634-46.
8. Stitt AW, He C, Vlassara H. Characterization of the advanced glycation endproduct receptor complex in human vascular endothelial cells. Biochem Biophys Res Commun 1999;256:549-56.
9. Stitt AW, Burke GA, Chen F, et al. Advanced glycation end-product receptor interactions on microvascular cells occur within caveolin-rich membrane domains. Faseb J 2000;14:2390-2.
10. Zhu W, Sano H, Nagai R, et al. The role of galectin-3 in endocytosis of advanced glycation end products and modified low density lipoproteins. Biochem Biophys Res Commun 2001;280:1183-8.
11. Seki N, Hashimoto N, Sano H, et al. Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells. Metabolism 2003;52:1558-03.
12. Handa JT, Reiser KM, Matsunaga H, et al. The advanced glycation endproduct pentosidine induces the expression of PDGF-B in human retinal pigment epithelial cells. Exp Eye Res 1998;66:411-19.
13. Lu M, Kuroki M, Amano S, et al. Advanced glycation end products increase retinal vascular endothelial growth factor expression. J Clin Invest 1998;101:1219-24.
14. Esposito C, Gerlach H, Brett J, et al. Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. J Exp Med 1989;170:1387-407.
15. Vlassara H, Brownlee M, Cerami A. Novel macrophage receptor for glucose-modified proteins is distinct from previously described scavenger receptors. J Exp Med 1986;164:1301-9.
16. Abel M, Ritthaler U, Zhang Y, et al. Expression of receptors for advanced glycosylated end-products in renal disease. Nephrol Dial Transplant 1995;10:1662-7.
17. Sano H, Nagai R, Matsumoto K, et al. Receptors for proteins modified by advanced glycation endproducts (AGE)-their functional role in atherosclerosis. Mech Ageing Dev 1999;107:333-46.
18. Li JJ, Dickson D, Hof PR, et al. Receptors for advanced glycosylation endproducts in human brain: role in brain homeostasis. Mol Med 1998;4:46-60.
19. Festa A, Schmolzer B, Schernthaner G, et al. Differential expression of receptors for advanced glycation end products on monocytes in patients with IDDM. Diabetologia 1998;41:674-80.
20. Patton WP, Chakravarthy U, Davies RJ, et al. Comet assay of UV-induced DNA damage in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1999;40:3268-75.
21. Stitt AW, Li YM, Gardiner TA, et al. Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats. Am J Pathol 1997;150:523-31.
22. Pugliese G, Pricci F, Leto G, et al. The diabetic milieu modulates the advanced glycation end product-receptor complex in the mesangium by inducing or upregulating galectin-3 expression. Diabetes 2000;49:1249-57.
23. Vlassara H. The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab Res Rev 2001;17:436-43.
24. He CJ, Koschinsky T, Buenting C, et al. Presence of diabetic complications in type 1 diabetic patients correlates with low expression of mononucleor cell AGE-receptor-1 and elevated serum AGE. Mol Med 2001;7:159-68.
25. Poirier O, Nicaud V, Vionnet N, et al. Polymorphism screening of four genes encoding advanced glycation end-product putative receptors. Association study with nephropathy in type 1 diabetic patients. Diabetes 2001;50:1214-18.
26. Pugliese G, Pricci F, Romeo G, et al. Upregulation of mesangial growth factor and extracellular matrix synthesis by advanced glycation end products via a receptor-mediated mechanism. Diabetes 1997;46:1881-7.
27. Gugliucci A, Bendayan M. Renal fate of circulating advanced glycated end products (AGE): evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells. Diabetologia 1996;39:149-60.
28. Kennedy CJ, Rakoczy PE, Constable IJ. Lipofuscin of the retinal pigment epithelium: a review. Eye 1995;9:763-71.
29. Pugliese G, Pricci F, Iacobini C, et al. Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice. Faseb J 2001;15:2471-9.
30. Iacobini C, Amadio L, Oddi G, et al. Role of galectin-3 in diabetic nephropathy. J Am Soc Nephrol 2003;14(Suppl 3):S264-70.
31. Yang RY, Liu FT. Galectins in cell growth and apaptosis. Cell Mol Life Sci 2003;60:267-76.
32. Menon RP, Hughes RC. Determinants in the N-terminal domains of galectin-3 for secretion by a novel pathway circumventing the endoplasmic reticulum-Golgi complex. Eur J Biochem 1999;264:569-76.