Developmental pathways during in vitro progression of human islet neogenesis

Differentiation

Volumn 77, Issue 2, 2009, Pages 135-147

  Dodge, Rikke ^a   Loomans, Cindy ^a   Sharma, Arun ^a   Bonner Weir, Susan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Differentiation; Ductal cells; Islet; Neogenesis; Pancreas

Indexed keywords

AQUAPORIN 1; AQUAPORIN 5; AUTOANTIGEN; BONE MORPHOGENETIC PROTEIN; COMPLEMENTARY DNA; FOLLISTATIN; GLUCAGON; INSULIN; MUCIN 6; NOTCH RECEPTOR; RETINOIC ACID; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ARTICLE; CELL DIFFERENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; NUCLEOTIDE SEQUENCE; PANCREAS DUCT; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TISSUE REGENERATION; UNINDEXED SEQUENCE;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; DOWN-REGULATION; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UBIQUITIN THIOLESTERASE; UP-REGULATION;

EID: 60549107020     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2008.09.015     Document Type: Article

References (53)

1. Al Awqati Q., Vijayakumar S., Takito J., Hikita C., Yan L., and Wiederholt T. Terminal differentiation in epithelia: the Hensin pathway in intercalated cells. Semin. Nephrol. 19 (1999) 415-420
2. al-Katib A.M., Mohammad R.M., Maki A., and Smith M.R. Induced expression of a ubiquitin COOH-terminal hydrolase in acute lymphoblastic leukemia. Cell Growth Differ. 6 (1995) 211-217
3. Apelqvist A., Li H., Sommer L., Beatus P., Anderson D.J., Honjo T., Hrabe de A.M., Lendahl U., and Edlund H. Notch signalling controls pancreatic cell differentiation. Nature 400 (1999) 877-881
4. Bisgaard H.C., Holmskov U., Santoni-Rugiu E., Nagy P., Nielsen O., Ott P., Hage E., Dalhoff K., Rasmussen L.J., and Tygstrup N. Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1. Am. J. Pathol. 161 (2002) 1187-1198
5. Bonner-Weir S., Trent D.F., and Weir G.C. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J. Clin. Invest. 71 (1983) 1544-1553
6. Bonner-Weir S., Baxter L.A., Schuppin G.T., and Smith F.E. A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 42 (1993) 1715-1720
7. Bonner-Weir S., Taneja M., Weir G.C., Tatarkiewicz K., Song K.H., Sharma A., and O'Neil J.J. In vitro cultivation of human islets from expanded ductal tissue. Proc. Natl. Acad. Sci. USA 97 (2000) 7999-8004
8. Boquist L., and Edstrom C. Ultrastructure of pancreatic acinar and islet parenchyma in rats at various intervals after duct ligation. Virchows Arch. A Pathol. Pathol. Anat. 349 (1970) 69-79
9. Cheng H., Bjerknes M., and Chen H. CRP-ductin: a gene expressed in intestinal crypts and in pancreatic and hepatic ducts. Anat. Rec. 244 (1996) 327-343
10. Cras-Meneur C., Inoue H., Zhou Y., Ohsugi M., Bernal-Mizrachi E., Pape D., Clifton S.W., and Permutt M.A. An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene Expression (SAGE). Diabetologia 47 (2004) 284-299
11. De Boer J., Wang H.J., and Van Blitterswijk C. Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells. Tissue Eng. 10 (2004) 393-401
12. Dichmann D.S., Miller C.P., Jensen J., Scott H.R., and Serup P. Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev. Dyn. 226 (2003) 663-674
13. Esni F., Ghosh B., Biankin A.V., Lin J.W., Albert M.A., Yu X., MacDonald R.J., Civin C.I., Real F.X., Pack M.A., Ball D.W., and Leach S.D. Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development 131 (2004) 4213-4224
14. Gao R., Ustinov J., Pulkkinen M.A., Lundin K., Korsgren O., and Otonkoski T. Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. Diabetes 52 (2003) 2007-2015
15. Gouon-Evans V., Rothenberg M.E., and Pollard J.W. Postnatal mammary gland development requires macrophages and eosinophils. Development 127 (2000) 2269-2282
16. Gu D., and Sarvetnick N. Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice. Development 118 (1993) 33-46
17. Heller R.S., Dichmann D.S., Jensen J., Miller C., Wong G., Madsen O.D., and Serup P. Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev. Dyn. 225 (2002) 260-270
18. Hikita C., Vijayakumar S., Takito J., Erdjument-Bromage H., Tempst P., and Al-Awqati Q. Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3. J. Cell Biol. 151 (2000) 1235-1246
19. Holmskov U., Mollenhauer J., Madsen J., Vitved L., Gronlund J., Tornoe I., Kliem A., Reid K.B., Poustka A., and Skjodt K. Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Proc. Natl. Acad. Sci. USA 96 (1999) 10794-10799
20. Hultquist G.T., Karlsson U., and Hallner A.C. The regenerative capacity of the pancreas in duct-ligated rats. Exp. Pathol. (Jena) 17 (1979) 44-52
21. Jensen J., Heller R.S., Funder-Nielsen T., Pedersen E.E., Lindsell C., Weinmaster G., Madsen O.D., and Serup P. Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes 49 (2000) 163-176
22. Jiang F.X., Stanley E.G., Gonez L.J., and Harrison L.C. Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells. J. Cell Sci. 115 (2002) 753-760
23. Jonas J.C., Sharma A., Hasenkamp W., Ilkova H., Patane G., Laybutt R., Bonner-Weir S., and Weir G.C. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J. Biol. Chem. 274 (1999) 14112-14121
24. Kengaku M., Twombly V., and Tabin C. Expression of Wnt and Frizzled genes during chick limb bud development. Cold Spring Harb. Symp. Quant. Biol. 62 (1997) 421-429
25. Lammert E., Brown J., and Melton D.A. Notch gene expression during pancreatic organogenesis. Mech. Dev. 94 (2000) 199-203
26. Leung W.K., Yu J., Chan F.K., To K.F., Chan M.W., Ebert M.P., Ng E.K., Chung S.C., Malfertheiner P., and Sung J.J. Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues. J. Pathol. 197 (2002) 582-588
27. Lin H.M., Pestell R.G., Raz A., and Kim H.R. Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells. Oncogene 21 (2002) 8001-8010
28. Massague J. TGF-beta signal transduction. Annu. Rev. Biochem. 67 (1998) 753-791
29. Miralles F., Czernichow P., and Scharfmann R. Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development. Development 125 (1998) 1017-1024
30. Miralles F., Lamotte L., Couton D., and Joshi R.L. Interplay between FGF10 and Notch signalling is required for the self-renewal of pancreatic progenitors. Int. J. Dev. Biol. 50 (2006) 17-26
31. Mollenhauer J., Deichmann M., Helmke B., Muller H., Kollender G., Holmskov U., Ligtenberg T., Krebs I., Wiemann S., Bantel-Schaal U., Madsen J., Bikker F., Klauck S.M., Otto H.F., Moldenhauer G., and Poustka A. Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. Int. J. Cancer 105 (2003) 149-157
32. Nishimura W., Kondo T., Salameh T., El K.I., Dodge R., Bonner-Weir S., and Sharma A. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev. Biol. (2006)
33. Ogawa K., Abe K., Kurosawa N., Kurohmaru M., Sugino H., Takahashi M., and Hayashi Y. Expression of alpha, beta A and beta B subunits of inhibin or activin and follistatin in rat pancreatic islets. FEBS Lett. 319 (1993) 217-220
34. Papadopoulou S., and Edlund H. Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function. Diabetes 54 (2005) 2844-2851
35. Pedersen A.H., and Heller R.S. A possible role for the canonical Wnt pathway in endocrine cell development in chicks. Biochem. Biophys. Res. Commun. 333 (2005) 961-968
36. Rafaeloff R., Qin X.F., Barlow S.W., Rosenberg L., and Vinik A.I. Identification of differentially expressed genes induced in pancreatic islet neogenesis. FEBS Lett. 378 (1996) 219-223
37. Roberts C., Roberts G.A., Lobner K., Bearzatto M., Clark A., Bonifacio E., and Christie M.R. Expression of the protein tyrosine phosphatase-like protein IA-2 during pancreatic islet development. J. Histochem. Cytochem. 49 (2001) 767-776
38. Rooman I., Heremans Y., Heimberg H., and Bouwens L. Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. Diabetologia 43 (2000) 907-914
39. Satoh J.I., and Kuroda Y. Ubiquitin C-terminal hydrolase-L1 (PGP9.5) expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines, neurotrophic factors or heat stress. Neuropathol. Appl. Neurobiol. 27 (2001) 95-104
40. Shapiro A.M., Lakey J.R., Ryan E.A., Korbutt G.S., Toth E., Warnock G.L., Kneteman N.M., and Rajotte R.V. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343 (2000) 230-238
41. Stoffers D.A., Kieffer T.J., Hussain M.A., Drucker D.J., Bonner-Weir S., Habener J.F., and Egan J.M. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49 (2000) 741-748
42. Thim L., and Mortz E. Isolation and characterization of putative trefoil peptide receptors. Regul. Pept. 90 (2000) 61-68
43. Tino M.J., and Wright J.R. Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner. Am. J. Respir. Cell Mol. Biol. 20 (1999) 759-768
44. Wang T.C., Bonner-Weir S., Oates P.S., Chulak M., Simon B., Merlino G.T., Schmidt E.V., and Brand S.J. Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J. Clin. Invest. 92 (1993) 1349-1356
45. Weaver C.V., Sorenson R.L., and Kaung H.C. Immunocytochemical localization of insulin-immunoreactive cells in the pancreatic ducts of rats treated with trypsin inhibitor. Diabetologia 28 (1985) 781-785
46. Wei C., Geras-Raaka E., Marcus-Samuels B., Oron Y., and Gershengorn M.C. Trypsin and thrombin accelerate aggregation of human endocrine pancreas precursor cells. J. Cell. Physiol. 206 (2006) 322-328
47. Wrana J.L., and Attisano L. The Smad pathway. Cytokine Growth Factor Rev. 11 (2000) 5-13
48. Xu G., Stoffers D.A., Habener J.F., and Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 (1999) 2270-2276
49. Yamamoto K., Miyagawa J., Waguri M., Sasada R., Igarashi K., Li M., Nammo T., Moriwaki M., Imagawa A., Yamagata K., Nakajima H., Namba M., Tochino Y., Hanafusa T., and Matsuzawa Y. Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion. Diabetes 49 (2000) 2021-2027
50. Yamaoka T., Idehara C., Yano M., Matsushita T., Yamada T., Ii S., Moritani M., Hata J., Sugino H., Noji S., and Itakura M. Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants. J. Clin. Invest. 102 (1998) 294-301
51. Yokoyama-Hayashi K., Takahashi T., Kakita A., and Yamashina S. Expression of PGP9.5 in ductal cells of the rat pancreas during development and regeneration: can it be a marker for pancreatic progenitor cells?. Endocr. J. 49 (2002) 61-74
52. Zhang Y.Q., Zhang H., Maeshima A., Kurihara H., Miyagawa J., Takeuchi T., and Kojima I. Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass. Endocrinology 143 (2002) 3540-3547
53. Zhang Y.Q., Cleary M.M., Si Y., Liu G., Eto Y., Kritzik M., Dabernat S., Kayali A.G., and Sarvetnick N. Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells. Diabetes 53 (2004) 2024-2033