Targeting B cells in multiple sclerosis. Current concepts and strategies;B-zell-gerichtete multiple-sklerose-therapie. Aktueller stand

Nervenarzt

Volumn 80, Issue 2, 2009, Pages 190-198

  Menge, T ^a   Budingen H C ^b   Dalakas, M C ^c   Kieseier, B C ^a   Hartung, H P ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Abteilung für Neurorehabilitation   (Switzerland)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Autoimmunity; B cells; Clinical studies; Multiple sclerosis; Therapy

Indexed keywords

BETA INTERFERON; GLATIRAMER; GLUCOCORTICOID; MITOXANTRONE; RITUXIMAB;

B LYMPHOCYTE; CYTOLOGY; HUMAN; LYMPHOCYTE DEPLETION; MULTIPLE SCLEROSIS; REVIEW;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD20; B-LYMPHOCYTES; DRUG DELIVERY SYSTEMS; HUMANS; MODELS, IMMUNOLOGICAL; MULTIPLE SCLEROSIS;

EID: 60349098419     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-008-2664-2     Document Type: Review

References (77)

1. Rituxan warning (2007) FDA Consum. 41:3
2. Allen 2004 Nat Immunol 5 943
3. Aloisi 2006 Nat Rev Immunol 6 205
4. Archelos 2000 Trends Neurosci 23 317
5. Archelos 2000 Ann Neurol 47 694
6. Ascherio 2007 Ann Neurol 61 288
7. Baker 2003 Arthritis Rheum 48 3253
8. Bar-Or 2008 Ann Neurol 63 395
9. Baranzini 1999 J Immunol 163 5133
10. Binder 2006 Blood 108 1975
11. Browning 2006 Nat Rev Drug Discov 5 564
12. Cepok 2001 Brain 124 2169
13. Cepok 2005 Brain 128 1667
14. Cohen 2007 J Autoimmun 29 246
15. Cohen 2006 Arthritis Rheum 54 2793
16. Corcione 2004 Proc Natl Acad Sci U S A 101 11064
17. Cree 2005 Neurology 64 1270
18. Cross 2006 J Neuroimmunol 180 63
19. Cross 2001 J Neuroimmunol 112 1
20. Dalakas 2006 Pharmacol Ther 112 57
21. Di 2003 J Immunol 171 1581
22. Dillon 2006 Nat Rev Drug Discov 5 235
23. Dorner 2008 Curr Opin Rheumatol 20 263
24. Duddy 2006 Int MS J 13 84
25. Duddy 2007 J Immunol 178 6092
26. Fillatreau 2002 Nat Immunol 3 944
27. Genain 1999 Nat Med 5 170
28. Gold 2006 Brain 129 1953
29. Goldberg 2002 Blood 99 1486
30. Gommerman 2003 Nat Rev Immunol 3 642
31. Gross 2001 Immunity 15 289
32. Hafler 2007 N Engl J Med 357 851
33. Harris HE (2008) Progressive multifocal leucoencephalopathy in a patient with systemic lupus erythematosus treated with rituximab. Rheumatology (Oxford) 47:224-225
34. Hauser 2008 N Engl J Med 358 676
35. Hawker K (2008) B-cell-targeted treatment for multiple sclerosis: mechanism of action and clinical data. Curr Opin Neurol 21 [Suppl 1]:19-25
36. Hemmer 2006 Nat Clin Pract Neurol 2 201
37. Hohlfeld 2005 Nat Clin Pract Neurol 1 34
38. Kabat 1947 J Exp Med 85 117
39. Kalled 2005 Immunol Rev 204 43
40. Keegan 2005 Lancet 366 579
41. Kleinschnitz 2007 Nervenarzt 78 883
42. Kranick 2007 Neurology 69 704
43. Krumbholz 2006 Brain 129 200
44. Krumbholz 2005 J Exp Med 201 195
45. Kuenz 2008 PLoS ONE 3 e2559
46. Liossis 2008 Clin Immunol 127 280
47. Lucchinetti 2000 Ann Neurol 47 707
48. Lund 2005 Curr Dir Autoimmun 8 25
49. Lutz 2007 J Autoimmun 29 287
50. Lyons 1999 Eur J Immunol 29 3432
51. Magliozzi 2004 J Neuroimmunol 148 11
52. Magliozzi 2007 Brain 130 1089
53. Meinl 2006 Ann Neurol 59 880
54. Molina 2008 Annu Rev Med 59 237
55. Monson 2005 Arch Neurol 62 258
56. Noseworthy 2000 N Engl J Med 343 938
57. Onrust 1999 Drugs 58 79
58. Owens 1998 Ann Neurol 43 236
59. Prineas 1979 Science 203 1123
60. Qin 1998 J Clin Invest 102 1045
61. Raine 1999 Ann Neurol 46 144
62. Reff 1994 Blood 83 435
63. Reiber 1998 Mult Scler 4 111
64. Rock 1984 J Exp Med 160 1102
65. Serafini 2006 J Neuropathol Exp Neurol 65 124
66. Shlomchik 2001 Nat Rev Immunol 1 147
67. Sospedra 2005 Annu Rev Immunol 23 683
68. Stuve 2005 Arch Neurol 62 1620
69. Tedder 2006 Springer Semin Immunopathol 28 351
70. Tiller 2007 Immunity 26 205
71. Uccelli 2005 Trends Immunol 26 254
72. von 2008 Eur J Immunol 38 2014
73. Wardemann 2003 Science 301 1374
74. Wingerchuk 2007 Lancet Neurol 6 805
75. Yurasov 2005 J Exp Med 201 703
76. Zhou 2007 J Autoimmun 29 219
77. Menge 2009 Drugs 68 2445