메뉴 건너뛰기




Volumn 292, Issue 2, 2009, Pages 225-233

Effects of intracerebroventricular injection of iron dextran on the iron concentration and divalent metal transporter 1 expression in the caudate putamen and substantia Nigra of rats

Author keywords

Brain iron metabolism; Caudate putamen; Divalent metal transporter 1; Intracerebroventricular injection; Substantia nigra

Indexed keywords

ANIMALS; CATION TRANSPORT PROTEINS; CAUDATE NUCLEUS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; IRON; IRON-DEXTRAN COMPLEX; MALE; PUTAMEN; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TIME FACTORS;

EID: 59949087430     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.20807     Document Type: Article
Times cited : (6)

References (53)
  • 2
  • 3
    • 0033044583 scopus 로고    scopus 로고
    • Iron transport across biologic membranes
    • Andrews NC, Fleming MD, Gunshin H. 1999 Iron transport across biologic membranes. Nutr Rev 57:114-123.
    • (1999) Nutr Rev , vol.57 , pp. 114-123
    • Andrews, N.C.1    Fleming, M.D.2    Gunshin, H.3
  • 6
    • 0031830710 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism
    • Calingasan NY, Park LCH, Calo LL, Trifiletti RR, Gandy SE, Gibson GE. 1998. Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism. Am J Pathol 153:599-610.
    • (1998) Am J Pathol , vol.153 , pp. 599-610
    • Calingasan, N.Y.1    Park, L.C.H.2    Calo, L.L.3    Trifiletti, R.R.4    Gandy, S.E.5    Gibson, G.E.6
  • 7
    • 0036310725 scopus 로고    scopus 로고
    • Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice
    • Canonne-Hergaux F, Gros P. 2002. Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice. Kidney Int 62:147-156.
    • (2002) Kidney Int , vol.62 , pp. 147-156
    • Canonne-Hergaux, F.1    Gros, P.2
  • 8
    • 0030058299 scopus 로고    scopus 로고
    • Molecular mechanisms of iron uptake in eukaryotes
    • De Silva DM, Askwith CC, Kaplan J. 1996. Molecular mechanisms of iron uptake in eukaryotes. Physiol Rev 76:31-47.
    • (1996) Physiol Rev , vol.76 , pp. 31-47
    • De Silva, D.M.1    Askwith, C.C.2    Kaplan, J.3
  • 9
    • 0024356620 scopus 로고
    • Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease
    • Dexter DT, Wells FR, Lees AJ, Agid F, Agid Y, Jenner P, Marsden CD. 1989. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J Neurochem 52:1830-1836.
    • (1989) J Neurochem , vol.52 , pp. 1830-1836
    • Dexter, D.T.1    Wells, F.R.2    Lees, A.J.3    Agid, F.4    Agid, Y.5    Jenner, P.6    Marsden, C.D.7
  • 10
  • 12
    • 0032898122 scopus 로고    scopus 로고
    • Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy
    • Griffiths PD, Dobson BR, Jones GR, Clarke DT. 1999. Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy. Brain 122:667-673.
    • (1999) Brain , vol.122 , pp. 667-673
    • Griffiths, P.D.1    Dobson, B.R.2    Jones, G.R.3    Clarke, D.T.4
  • 13
    • 0033103978 scopus 로고    scopus 로고
    • The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes
    • Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. 1999. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. J Exp Med 189:831-841.
    • (1999) J Exp Med , vol.189 , pp. 831-841
    • Gruenheid, S.1    Canonne-Hergaux, F.2    Gauthier, S.3    Hackam, D.J.4    Grinstein, S.5    Gros, P.6
  • 14
    • 0028962892 scopus 로고
    • Identification and characterization of a second mouse Nramp gene
    • Gruenheid S, Cellier M, Vidal S, Gros P. 1995. Identification and characterization of a second mouse Nramp gene. Genomics 25: 514-525.
    • (1995) Genomics , vol.25 , pp. 514-525
    • Gruenheid, S.1    Cellier, M.2    Vidal, S.3    Gros, P.4
  • 17
    • 0032875387 scopus 로고    scopus 로고
    • Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
    • Harris ZL, Durley AP, Man TK, Gitlin JD. 1999. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci USA 96:10812-10817.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10812-10817
    • Harris, Z.L.1    Durley, A.P.2    Man, T.K.3    Gitlin, J.D.4
  • 18
    • 4644365735 scopus 로고    scopus 로고
    • Distribution of divalent metal transporter-1 in the monkey basal ganglia
    • Huang E, Ong WY, Connor JR. 2004. Distribution of divalent metal transporter-1 in the monkey basal ganglia. Neuroscience 128: 487-496.
    • (2004) Neuroscience , vol.128 , pp. 487-496
    • Huang, E.1    Ong, W.Y.2    Connor, J.R.3
  • 19
    • 0037126002 scopus 로고    scopus 로고
    • Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
    • Hubert N, Hentze MW. 2002. Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc Natl Acad Sci USA 99:12345-12350.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12345-12350
    • Hubert, N.1    Hentze, M.W.2
  • 20
    • 0032975570 scopus 로고    scopus 로고
    • The role of iron in neurodegeneration: Prospects for pharmacotherapy of Parkinson's disease
    • Jellinger KA. 1999. The role of iron in neurodegeneration: prospects for pharmacotherapy of Parkinson's disease. Drugs Aging 14:115-140.
    • (1999) Drugs Aging , vol.14 , pp. 115-140
    • Jellinger, K.A.1
  • 21
    • 13644278965 scopus 로고    scopus 로고
    • Age-dependent and iron-independent expression of two mRNA isoforms of divalent metal transporter 1 in rat brain
    • Ke Y, Chang YZ, Duan XL, Du JR, Zhu L, Wang K, Yang XD, Ho KP, Qian ZM. 2005. Age-dependent and iron-independent expression of two mRNA isoforms of divalent metal transporter 1 in rat brain. Neurobiol Aging 26:739-748.
    • (2005) Neurobiol Aging , vol.26 , pp. 739-748
    • Ke, Y.1    Chang, Y.Z.2    Duan3    XL, D.J.4    Zhu, L.5    Wang, K.6    Yang, X.D.7    Ho, K.P.8    Qian, Z.M.9
  • 23
    • 0345714885 scopus 로고    scopus 로고
    • Iron misregulation in the brain: A primary cause of neurodegenerative disorders
    • Ke Y, Qian ZM. 2003. Iron misregulation in the brain: a primary cause of neurodegenerative disorders. Lancet Neurol 2:246-253.
    • (2003) Lancet Neurol , vol.2 , pp. 246-253
    • Ke, Y.1    Qian, Z.M.2
  • 24
    • 2542515348 scopus 로고    scopus 로고
    • Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain
    • Knutson M, Menzies S, Connor J, Wessling-Resnick M. 2004. Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain. J Neurosci Res 76:633-641.
    • (2004) J Neurosci Res , vol.76 , pp. 633-641
    • Knutson, M.1    Menzies, S.2    Connor, J.3    Wessling-Resnick, M.4
  • 25
    • 0032780616 scopus 로고    scopus 로고
    • Mechanisms underlying pressor response of subfornical organ to angiotensin II
    • Ku YH, Jia YF, Chang YZ. 1999. Mechanisms underlying pressor response of subfornical organ to angiotensin II. Peptides 20: 171-176.
    • (1999) Peptides , vol.20 , pp. 171-176
    • Ku, Y.H.1    Jia, Y.F.2    Chang, Y.Z.3
  • 26
    • 0032104739 scopus 로고    scopus 로고
    • The human Nramp2 gene: Characterization of the gene structure, alternative splicing, promoter region and polymorphisms
    • Lee PL, Gelbart T, West C, Halloran C, Beutler E. 1998. The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms. Blood Cell Mol Dis 24:199-215.
    • (1998) Blood Cell Mol Dis , vol.24 , pp. 199-215
    • Lee, P.L.1    Gelbart, T.2    West, C.3    Halloran, C.4    Beutler, E.5
  • 27
    • 0031918718 scopus 로고    scopus 로고
    • Increased basal ganglia iron in striatonigral degeneration: In vivo estimation with magnetic resonance
    • Martin W, Roberts T, Ye F, Allen P. 1998. Increased basal ganglia iron in striatonigral degeneration: in vivo estimation with magnetic resonance. Can J Neurol Sci 25:44-47.
    • (1998) Can J Neurol Sci , vol.25 , pp. 44-47
    • Martin, W.1    Roberts, T.2    Ye, F.3    Allen, P.4
  • 29
    • 0032549868 scopus 로고    scopus 로고
    • Kinetics and distribution of [59Fe-125I] transferrin injected into the ventricular system of the rat
    • Moos T, Morgan EH. 1998. Kinetics and distribution of [59Fe-125I] transferrin injected into the ventricular system of the rat. Brain Res 790:115-128.
    • (1998) Brain Res , vol.790 , pp. 115-128
    • Moos, T.1    Morgan, E.H.2
  • 30
    • 1842504357 scopus 로고    scopus 로고
    • The metabolism of neuronal iron and its pathogenic role in neurological disease: Review
    • Moos T, Morgan EH. 2004. The metabolism of neuronal iron and its pathogenic role in neurological disease: review. Ann NY Acad Sci 1012:14-26.
    • (2004) Ann NY Acad Sci , vol.1012 , pp. 14-26
    • Moos, T.1    Morgan, E.H.2
  • 31
    • 0036721552 scopus 로고    scopus 로고
    • Effect of iron status on DMT1 expression in duodenal enterocytes from beta 2-microglobulin knockout mice
    • Moos T, Trinder D, Morgan EH. 2002. Effect of iron status on DMT1 expression in duodenal enterocytes from beta 2-microglobulin knockout mice. Am J Physiol Gastrointest Liver Physiol 283:G687-G694.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Moos, T.1    Trinder, D.2    Morgan, E.H.3
  • 32
    • 0036703490 scopus 로고    scopus 로고
    • Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury
    • Patel BN, Dunn RJ, Jeong SY, Zhu Q, Julien JP, David S. 2002. Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury. J Neurosci 22:6578-6586.
    • (2002) J Neurosci , vol.22 , pp. 6578-6586
    • Patel, B.N.1    Dunn, R.J.2    Jeong, S.Y.3    Zhu, Q.4    Julien, J.P.5    David, S.6
  • 33
    • 0035095564 scopus 로고    scopus 로고
    • Brain iron transport and neurodegeneration
    • Qian ZM, Shen X. 2001. Brain iron transport and neurodegeneration. Trends Mol Med 7:103-108.
    • (2001) Trends Mol Med , vol.7 , pp. 103-108
    • Qian, Z.M.1    Shen, X.2
  • 34
    • 0010487727 scopus 로고    scopus 로고
    • Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders
    • Qian ZM, Wang Q. 1998. Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders. Brain Res Brain Res Rev 27:257-267.
    • (1998) Brain Res Brain Res Rev , vol.27 , pp. 257-267
    • Qian, Z.M.1    Wang, Q.2
  • 35
    • 0035824273 scopus 로고    scopus 로고
    • Distribution of iron in the parrot brain: Conserved (pallidal) and derived (nigral) labeling patterns
    • Roberts TF, Brauth SE, Hall WS. 2001. Distribution of iron in the parrot brain: conserved (pallidal) and derived (nigral) labeling patterns. Brain Res 921:138-149.
    • (2001) Brain Res , vol.921 , pp. 138-149
    • Roberts, T.F.1    Brauth, S.E.2    Hall, W.S.3
  • 37
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • Smith MA, Harris PL, Sayre LM, Perry G. 1997. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA 94:9866-9868.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 38
    • 0032530922 scopus 로고    scopus 로고
    • The G185R mutation disrupts function of the iron transporter Nramp2
    • Su MA, Trenor CC, Fleming JC, Templeton DM. 1998. The G185R mutation disrupts function of the iron transporter Nramp2. Blood 92:2157-2163.
    • (1998) Blood , vol.92 , pp. 2157-2163
    • Su, M.A.1    Trenor, C.C.2    Fleming, J.C.3    Templeton, D.M.4
  • 39
    • 0026317374 scopus 로고
    • Hallervorden-Spatz syndrome and brain iron metabolism
    • Swaiman KF. 1991. Hallervorden-Spatz syndrome and brain iron metabolism. Arch Neurol 48:1285-1293.
    • (1991) Arch Neurol , vol.48 , pp. 1285-1293
    • Swaiman, K.F.1
  • 40
    • 0034698023 scopus 로고    scopus 로고
    • Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 Cells
    • Tabuchi M, Yoshimori T, Yamaguchi K, Yoshida T, Kishi F. 2000. Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 Cells. J Biol Chem 275:22220-22228.
    • (2000) J Biol Chem , vol.275 , pp. 22220-22228
    • Tabuchi, M.1    Yoshimori, T.2    Yamaguchi, K.3    Yoshida, T.4    Kishi, F.5
  • 41
    • 0033984237 scopus 로고    scopus 로고
    • Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells
    • Tandy S, Williams M, Leggett A, Lopez-Jimenez M, Dedes M, Ramesh B, Srai SK, Sharp P 2000. Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells. J Biol Chem 275:1023-1029.
    • (2000) J Biol Chem , vol.275 , pp. 1023-1029
    • Tandy, S.1    Williams, M.2    Leggett, A.3    Lopez-Jimenez, M.4    Dedes, M.5    Ramesh, B.6    Srai, S.K.7    Sharp, P.8
  • 42
    • 0038491413 scopus 로고    scopus 로고
    • dynamic traf.c through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor
    • Touret N, Furuya W, Forbes J, Gros P, Grinstein S. 2003. dynamic traf.c through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem 278:25548-25557.
    • (2003) J Biol Chem , vol.278 , pp. 25548-25557
    • Touret, N.1    Furuya, W.2    Forbes, J.3    Gros, P.4    Grinstein, S.5
  • 43
    • 0034070941 scopus 로고    scopus 로고
    • Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload
    • Trinder D, Oates PS, Thomas C, Sadleir J, Morgan EH. 2000. Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload. Gut 46:270-276.
    • (2000) Gut , vol.46 , pp. 270-276
    • Trinder, D.1    Oates, P.S.2    Thomas, C.3    Sadleir, J.4    Morgan, E.H.5
  • 44
    • 0035732296 scopus 로고    scopus 로고
    • A light and electron microscopic study of the iron transporter protein DMT-1 in the monkey cerebral neocortex and hippocampus
    • Wang XS, Ong WY, Connor JR. 2001. A light and electron microscopic study of the iron transporter protein DMT-1 in the monkey cerebral neocortex and hippocampus. J Neurocytol 30:353-360.
    • (2001) J Neurocytol , vol.30 , pp. 353-360
    • Wang, X.S.1    Ong, W.Y.2    Connor, J.R.3
  • 45
    • 0036197931 scopus 로고    scopus 로고
    • Increase in ferric and ferrous iron in the rat hippocampus with time after kainate-induced excitotoxic injury
    • Wang XS, Ong WY, Connor JR. 2002a. Increase in ferric and ferrous iron in the rat hippocampus with time after kainate-induced excitotoxic injury. Exp Brain Res 143:137-148.
    • (2002) Exp Brain Res , vol.143 , pp. 137-148
    • Wang, X.S.1    Ong, W.Y.2    Connor, J.R.3
  • 46
    • 0036434205 scopus 로고    scopus 로고
    • A light and electron microscopic study of divalent metal transporter-1 distribution in the rat hippocampus, after kainate-induced neuronal injury
    • Wang XS, Ong WY, Connor JR. 2002b. A light and electron microscopic study of divalent metal transporter-1 distribution in the rat hippocampus, after kainate-induced neuronal injury. Exp Neurol 177:193-201.
    • (2002) Exp Neurol , vol.177 , pp. 193-201
    • Wang, X.S.1    Ong, W.Y.2    Connor, J.R.3
  • 47
    • 0033167931 scopus 로고    scopus 로고
    • The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake
    • Wardrop SL, Richardson DR. 1999. The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake. Eur J Biochem 263:41-49.
    • (1999) Eur J Biochem , vol.263 , pp. 41-49
    • Wardrop, S.L.1    Richardson, D.R.2
  • 48
    • 0033769626 scopus 로고    scopus 로고
    • Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages
    • Wardrop SL, Richardson DR. 2000. Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages. Eur J Biochem 267:6586-6593.
    • (2000) Eur J Biochem , vol.267 , pp. 6586-6593
    • Wardrop, S.L.1    Richardson, D.R.2
  • 49
    • 1042273883 scopus 로고    scopus 로고
    • Regulation and developmental expression of the divalent metal-ion transporter in the rat brain
    • Williams K, Wilson MA, Bressler J. 2000. Regulation and developmental expression of the divalent metal-ion transporter in the rat brain. Cell Mol Biol (Noisy-le-grand) 46:563-571.
    • (2000) Cell Mol Biol (Noisy-le-grand) , vol.46 , pp. 563-571
    • Williams, K.1    Wilson, M.A.2    Bressler, J.3
  • 50
    • 0036152892 scopus 로고    scopus 로고
    • Iron and Parkinson's disease
    • Wolozin B, Golts N. 2002. Iron and Parkinson's disease. Neuroscientist 8:22-32.
    • (2002) Neuroscientist , vol.8 , pp. 22-32
    • Wolozin, B.1    Golts, N.2
  • 52
    • 0035800585 scopus 로고    scopus 로고
    • In vivo perfusion Turnbull's reaction' for Fe(II) histochemistry in nonanoxic/ non-ischemic and anoxic/ischemic cat brains
    • Yu S, Iwatsuki H, Ichinohe N, Mori F, Shoumura K. 2001. 'In vivo perfusion Turnbull's reaction' for Fe(II) histochemistry in nonanoxic/ non-ischemic and anoxic/ischemic cat brains. Neurosci Lett 308:79-82.
    • (2001) Neurosci Lett , vol.308 , pp. 79-82
    • Yu, S.1    Iwatsuki, H.2    Ichinohe, N.3    Mori, F.4    Shoumura, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.