메뉴 건너뛰기




Volumn 31, Issue 6, 2008, Pages 353-362

Role of sildenafil in neurological disorders

Author keywords

Amnesia; Cerebrovascular disorders; Intracranial hemorrhage; Neurodegenerative; Optic neuropathy; Phosphodiesterase 5 inhibitor; Retinal and ocular disorders; Seizures; Sildenafil; Subarachnoid hemorrhage

Indexed keywords

CYCLIC GMP; NITRIC OXIDE; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; CYCLIC GMP PHOSPHODIESTERASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SULFONE;

EID: 59849087724     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNF.0b013e31815cd94c     Document Type: Article
Times cited : (46)

References (74)
  • 1
    • 0036713960 scopus 로고    scopus 로고
    • The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects
    • Kruuse C, Thomsen LL, Jacobsen TB, et al. The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects. J Cereb Blood Flow Metab 2002;22: 1124-1131.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1124-1131
    • Kruuse, C.1    Thomsen, L.L.2    Jacobsen, T.B.3
  • 2
    • 84868951797 scopus 로고    scopus 로고
    • FDA sildenafil citrate information. Available at
    • FDA sildenafil citrate information. Available at: http://www.fda.gov/ cder/consumerinfo/viagra/.
  • 3
    • 0036673903 scopus 로고    scopus 로고
    • Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes
    • Desouza C, Parulkar A, Lumpkin D, et al. Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes. Diabetes Care 2002;25:1336-1339.
    • (2002) Diabetes Care , vol.25 , pp. 1336-1339
    • Desouza, C.1    Parulkar, A.2    Lumpkin, D.3
  • 4
    • 25444473998 scopus 로고    scopus 로고
    • Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study
    • Diomedi M, Sallustio F, Rizzato B, et al. Sildenafil increases cerebrovascular reactivity: a transcranial Doppler study. Neurology 2005;65:919-921.
    • (2005) Neurology , vol.65 , pp. 919-921
    • Diomedi, M.1    Sallustio, F.2    Rizzato, B.3
  • 5
    • 4644296436 scopus 로고    scopus 로고
    • Plasma levels of cAMP, cGMP and CGRP in sildenafil-induced headache
    • Kruuse C, Frandsen E, Schifter S, et al. Plasma levels of cAMP, cGMP and CGRP in sildenafil-induced headache. Cephalalgia 2004;24:547-553.
    • (2004) Cephalalgia , vol.24 , pp. 547-553
    • Kruuse, C.1    Frandsen, E.2    Schifter, S.3
  • 6
    • 0031861609 scopus 로고    scopus 로고
    • Clinical safety of oral sildenafil citrate (VIAGRA) in the treatment of erectile dysfunction
    • Morales AGC, Collins M, Wicker PA, et al. Clinical safety of oral sildenafil citrate (VIAGRA) in the treatment of erectile dysfunction. Int J Impot Res 1998;10:69-73.
    • (1998) Int J Impot Res , vol.10 , pp. 69-73
    • Morales, A.G.C.1    Collins, M.2    Wicker, P.A.3
  • 7
    • 0033522214 scopus 로고    scopus 로고
    • Overall cardiovascular profile of sildenafil citrate
    • Zusman RM, Morales A, Glasser DB, et al. Overall cardiovascular profile of sildenafil citrate. Am J Cardiol 1999;83:35C-44C.
    • (1999) Am J Cardiol , vol.83
    • Zusman, R.M.1    Morales, A.2    Glasser, D.B.3
  • 8
    • 66249100436 scopus 로고    scopus 로고
    • US Physician Prescribing Information. Division of Pfizer, Inc, NY
    • Labs. Viagra
    • Pfizer Labs. Viagra US Physician Prescribing Information. Division of Pfizer, Inc, NY; 2006:1-24.
    • (2006) , pp. 1-24
    • Pfizer1
  • 9
    • 0037383775 scopus 로고    scopus 로고
    • Effect of sildenafil (Viagra) on cerebral blood flow velocity: A pilot study
    • Arnavaz A, Aurich A, Weissenborn K, et al. Effect of sildenafil (Viagra) on cerebral blood flow velocity: a pilot study. Psychiatry Res 2003;122:207-209.
    • (2003) Psychiatry Res , vol.122 , pp. 207-209
    • Arnavaz, A.1    Aurich, A.2    Weissenborn, K.3
  • 10
    • 12844262177 scopus 로고    scopus 로고
    • Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts
    • Erceg S, Monfort P, Hernandez-Viadel M, et al. Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Hepatology 2005;41: 299-306.
    • (2005) Hepatology , vol.41 , pp. 299-306
    • Erceg, S.1    Monfort, P.2    Hernandez-Viadel, M.3
  • 11
    • 0018904811 scopus 로고
    • Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning
    • Fisher CM, Kistler JP, Davis JM. Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 1980;6:1-9.
    • (1980) Neurosurgery , vol.6 , pp. 1-9
    • Fisher, C.M.1    Kistler, J.P.2    Davis, J.M.3
  • 12
    • 25444436667 scopus 로고    scopus 로고
    • Effect of sildenafil (Viagra) on cerebral blood vessels
    • Johnston KC. Effect of sildenafil (Viagra) on cerebral blood vessels. Neurology 2005;65:785.
    • (2005) Neurology , vol.65 , pp. 785
    • Johnston, K.C.1
  • 13
    • 0036561750 scopus 로고    scopus 로고
    • Exaggerated interictal cerebrovascular reactivity but normal blood flow velocities in migraine without aura
    • Dora B, Balkan S. Exaggerated interictal cerebrovascular reactivity but normal blood flow velocities in migraine without aura. Cephalalgia 2002;22:288-290.
    • (2002) Cephalalgia , vol.22 , pp. 288-290
    • Dora, B.1    Balkan, S.2
  • 14
    • 0037137047 scopus 로고    scopus 로고
    • Tonic-clonic seizures in patients taking sildenafil
    • Gilad R, Lampl Y, Eshel Y, et al. Tonic-clonic seizures in patients taking sildenafil. BMJ. 2002; 325:869.
    • (2002) BMJ , vol.325 , pp. 869
    • Gilad, R.1    Lampl, Y.2    Eshel, Y.3
  • 15
    • 33646593150 scopus 로고    scopus 로고
    • The proconvulsant effect of sildenafil in mice: Role of nitric oxide-cGMP pathway
    • Riazi K, Roshanpour M, Rafiei-Tabatabaei N, et al. The proconvulsant effect of sildenafil in mice: role of nitric oxide-cGMP pathway. Br J Pharmacol 2006;147:935-943.
    • (2006) Br J Pharmacol , vol.147 , pp. 935-943
    • Riazi, K.1    Roshanpour, M.2    Rafiei-Tabatabaei, N.3
  • 16
    • 0032445219 scopus 로고    scopus 로고
    • Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes
    • Ballard SA, Gingell CJ, Tang K, et al. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 1998;159:2164-2171.
    • (1998) J Urol , vol.159 , pp. 2164-2171
    • Ballard, S.A.1    Gingell, C.J.2    Tang, K.3
  • 17
    • 0042844737 scopus 로고    scopus 로고
    • Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): In vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation
    • Shimizu-Albergine M, Rybalkin SD, Rybalkina IG, et al. Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): in vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation. J Neurosci 2003;23: 6452-6459.
    • (2003) J Neurosci , vol.23 , pp. 6452-6459
    • Shimizu-Albergine, M.1    Rybalkin, S.D.2    Rybalkina, I.G.3
  • 18
    • 0015231739 scopus 로고
    • Multiple cyclic nucleotide phosphodiesterase activities from rat brain
    • Thompson WJ, Appleman MM. Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry 1971;10:311-316.
    • (1971) Biochemistry , vol.10 , pp. 311-316
    • Thompson, W.J.1    Appleman, M.M.2
  • 19
    • 14844303317 scopus 로고    scopus 로고
    • Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    • Barnes AP, Livera G, Huang P, et al. Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium. J Biol Chem 2005;280:7997-8003.
    • (2005) J Biol Chem , vol.280 , pp. 7997-8003
    • Barnes, A.P.1    Livera, G.2    Huang, P.3
  • 20
    • 0026566697 scopus 로고
    • The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung
    • Burns F, Rodger IW, Pyne NJ. The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung. Biochem J 1992;283(Pt 2): 487-491.
    • (1992) Biochem J , vol.283 , Issue.PART 2 , pp. 487-491
    • Burns, F.1    Rodger, I.W.2    Pyne, N.J.3
  • 21
    • 33847068206 scopus 로고    scopus 로고
    • Overview of PDEs and their regulation
    • Omori K, Kotera J. Overview of PDEs and their regulation. Circ Res 2007;100:309-327.
    • (2007) Circ Res , vol.100 , pp. 309-327
    • Omori, K.1    Kotera, J.2
  • 22
    • 33947494913 scopus 로고    scopus 로고
    • Regulation of phospho-diesterase 3 and inducible cAMP early repressor in the heart
    • Yan C, Miller CL, Abe J. Regulation of phospho-diesterase 3 and inducible cAMP early repressor in the heart. Circ Res 2007;100:489-501.
    • (2007) Circ Res , vol.100 , pp. 489-501
    • Yan, C.1    Miller, C.L.2    Abe, J.3
  • 23
    • 33845188745 scopus 로고    scopus 로고
    • Systemic administration of phosphodiesterase V inhibitor, sildenafil citrate, for attenuation of cerebral vasospasm after experimental subarachnoid hemorrhage
    • discussion 1107-1108
    • Atalay B, Caner H, Cekinmez M, et al. Systemic administration of phosphodiesterase V inhibitor, sildenafil citrate, for attenuation of cerebral vasospasm after experimental subarachnoid hemorrhage. Neurosurgery 2006;59:1102-1107; discussion 1107-1108.
    • (2006) Neurosurgery , vol.59 , pp. 1102-1107
    • Atalay, B.1    Caner, H.2    Cekinmez, M.3
  • 25
    • 0036715708 scopus 로고    scopus 로고
    • Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model
    • Inoha S, Inamura T, Ikezaki K, et al. Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model. Neurol Res 2002;24:607-612.
    • (2002) Neurol Res , vol.24 , pp. 607-612
    • Inoha, S.1    Inamura, T.2    Ikezaki, K.3
  • 26
    • 33645788620 scopus 로고    scopus 로고
    • Sildenafil improves dynamic vascular function in the brain: Studies in patients with pulmonary hypertension
    • Rosengarten B, Schermuly RT, Voswinckel R, et al. Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension. Cerebrovasc Dis 2006; 21:194-200.
    • (2006) Cerebrovasc Dis , vol.21 , pp. 194-200
    • Rosengarten, B.1    Schermuly, R.T.2    Voswinckel, R.3
  • 27
    • 0035856423 scopus 로고    scopus 로고
    • Transient ischemic attack and stroke associated with sildenafil (Viagra) use
    • Morgan JC, Alhatou M, Oberlies J, et al. Transient ischemic attack and stroke associated with sildenafil (Viagra) use. Neurology 2001;57:1730-1731.
    • (2001) Neurology , vol.57 , pp. 1730-1731
    • Morgan, J.C.1    Alhatou, M.2    Oberlies, J.3
  • 28
    • 33746412518 scopus 로고    scopus 로고
    • Stroke-an adverse reaction to sildenafil
    • Habek M, Petravić D. Stroke-an adverse reaction to sildenafil. Clin Neuropharmacol. 2006;29:165-167.
    • (2006) Clin Neuropharmacol , vol.29 , pp. 165-167
    • Habek, M.1    Petravić, D.2
  • 29
    • 0342723791 scopus 로고    scopus 로고
    • Nitric Oxide in the pathogenesis of vascular disease
    • Li H, Forstermann U. Nitric Oxide in the pathogenesis of vascular disease. J Pathol 2000; 190:244-254.
    • (2000) J Pathol , vol.190 , pp. 244-254
    • Li, H.1    Forstermann, U.2
  • 30
    • 0029934405 scopus 로고    scopus 로고
    • ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats
    • Zhang Z, Reif D, Macdonald J, et al. ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 1996;16:599-604.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 599-604
    • Zhang, Z.1    Reif, D.2    Macdonald, J.3
  • 31
    • 0034754052 scopus 로고    scopus 로고
    • A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats
    • Zhang R, Zhang L, Zhang Z, et al. A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats. Ann Neurol 2001;50: 602-611.
    • (2001) Ann Neurol , vol.50 , pp. 602-611
    • Zhang, R.1    Zhang, L.2    Zhang, Z.3
  • 32
    • 0037458918 scopus 로고    scopus 로고
    • Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat
    • Zhang R, Wang L, Zhang L, et al. Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat. Circ Res 2003;92:308-313.
    • (2003) Circ Res , vol.92 , pp. 308-313
    • Zhang, R.1    Wang, L.2    Zhang, L.3
  • 33
    • 0034848647 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide
    • Bussolati B, Dunk C, Grohman M, et al. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide. Am J Pathol 2001;159: 993-1008.
    • (2001) Am J Pathol , vol.159 , pp. 993-1008
    • Bussolati, B.1    Dunk, C.2    Grohman, M.3
  • 34
    • 0033619780 scopus 로고    scopus 로고
    • A novel function of VEGF receptor-2 (KDR): Rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cells
    • Kroll J, Waltenberger J. A novel function of VEGF receptor-2 (KDR): rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cells. Biochem Biophys Res Commun 1999;265: 636-639.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 636-639
    • Kroll, J.1    Waltenberger, J.2
  • 35
    • 0034834809 scopus 로고    scopus 로고
    • Sildenafil (Viagra)-induced spontaneous intracerebral haemorrhage
    • Buxton N, Flannery T, Wild D, et al. Sildenafil (Viagra)-induced spontaneous intracerebral haemorrhage. Br J Neurosurg 2001;15:347-349.
    • (2001) Br J Neurosurg , vol.15 , pp. 347-349
    • Buxton, N.1    Flannery, T.2    Wild, D.3
  • 36
    • 0035082556 scopus 로고    scopus 로고
    • Intracerebral haemorrhage associated with sildenafil citrate
    • Monastero R, Pipia C, Camarda LK, et al. Intracerebral haemorrhage associated with sildenafil citrate. J Neurol 2001;248:141-142.
    • (2001) J Neurol , vol.248 , pp. 141-142
    • Monastero, R.1    Pipia, C.2    Camarda, L.K.3
  • 37
    • 3543081006 scopus 로고    scopus 로고
    • Hemiballism due to sildenafil use
    • Marti I, Marti Masso JF. Hemiballism due to sildenafil use. Neurology 2004;63:534.
    • (2004) Neurology , vol.63 , pp. 534
    • Marti, I.1    Marti Masso, J.F.2
  • 38
    • 0032167976 scopus 로고    scopus 로고
    • Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra)
    • Donahue SP, Taylor RJ. Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra). Am J Ophthalmol 1998;126:476-477.
    • (1998) Am J Ophthalmol , vol.126 , pp. 476-477
    • Donahue, S.P.1    Taylor, R.J.2
  • 39
    • 33645731017 scopus 로고    scopus 로고
    • Ocular safety in patients using sildenafil citrate therapy for erectile dysfunction
    • Laties A, Sharlip I. Ocular safety in patients using sildenafil citrate therapy for erectile dysfunction. J Sex Med 2006;3:12-27.
    • (2006) J Sex Med , vol.3 , pp. 12-27
    • Laties, A.1    Sharlip, I.2
  • 40
    • 1442274760 scopus 로고    scopus 로고
    • Blood pressure and stroke: An overview of published reviews
    • Lawes CM, Bennett DA, Feigin VL, et al. Blood pressure and stroke: an overview of published reviews. Stroke 2004;35:776-785.
    • (2004) Stroke , vol.35 , pp. 776-785
    • Lawes, C.M.1    Bennett, D.A.2    Feigin, V.L.3
  • 41
    • 0032445219 scopus 로고    scopus 로고
    • Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes
    • Ballard S, Gingell CJ, Tang K, et al. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 1998;159:2164-2171.
    • (1998) J Urol , vol.159 , pp. 2164-2171
    • Ballard, S.1    Gingell, C.J.2    Tang, K.3
  • 42
    • 0032516296 scopus 로고    scopus 로고
    • Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group
    • Goldstein I, Lue TF, Padma-Nathan H, et al. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med 1998;338: 1397-1404.
    • (1998) N Engl J Med , vol.338 , pp. 1397-1404
    • Goldstein, I.1    Lue, T.F.2    Padma-Nathan, H.3
  • 43
    • 33646712814 scopus 로고    scopus 로고
    • Sildenafil increases cerebrovascular reactivity: A transcranial Doppler study
    • Brenner S. Sildenafil increases cerebrovascular reactivity: a transcranial Doppler study. Neurology 2006;66:1455-1456.
    • (2006) Neurology , vol.66 , pp. 1455-1456
    • Brenner, S.1
  • 44
    • 33645978101 scopus 로고    scopus 로고
    • de L. Figuerola, M, Bruera O, Leston J, et al. Cluster headache attack due to sildenafil intake. Cephalalgia 2006;26:617-619.
    • de L. Figuerola, M, Bruera O, Leston J, et al. Cluster headache attack due to sildenafil intake. Cephalalgia 2006;26:617-619.
  • 45
    • 33645099900 scopus 로고    scopus 로고
    • Sildenafil can trigger cluster headaches
    • Evans RW. Sildenafil can trigger cluster headaches. Headache 2006;46:173-174.
    • (2006) Headache , vol.46 , pp. 173-174
    • Evans, R.W.1
  • 46
    • 0036715708 scopus 로고    scopus 로고
    • Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model
    • Inoha S, Inamura T, Ikezaki K, et al. Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model. Neurol Res 2002;24: 607-612.
    • (2002) Neurol Res , vol.24 , pp. 607-612
    • Inoha, S.1    Inamura, T.2    Ikezaki, K.3
  • 47
    • 0029878999 scopus 로고    scopus 로고
    • Risk factors for subarachnoid hemorrhage: A systematic review
    • Teunissen LL, Rinkel GJ, Algra A. Risk factors for subarachnoid hemorrhage: a systematic review. Stroke 1996;27:544-549.
    • (1996) Stroke , vol.27 , pp. 544-549
    • Teunissen, L.L.1    Rinkel, G.J.2    Algra, A.3
  • 48
    • 0033620379 scopus 로고    scopus 로고
    • Prevention of a first stroke: A review of guidelines and a multidisciplinary consensus statement from the National Stroke Association
    • Gorelick PB, Sacco RL, Smith DB, et al. Prevention of a first stroke: a review of guidelines and a multidisciplinary consensus statement from the National Stroke Association. JAMA 1999;281: 1112-1120.
    • (1999) JAMA , vol.281 , pp. 1112-1120
    • Gorelick, P.B.1    Sacco, R.L.2    Smith, D.B.3
  • 49
    • 0029061064 scopus 로고
    • Medical complications of aneurysmal subarachnoid hemorrhage: A report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study
    • Solenski NJ, Haley EC, Jr Kassell NF, et al. Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study. Crit Care Med 1995;23:1007-1017.
    • (1995) Crit Care Med , vol.23 , pp. 1007-1017
    • Solenski, N.J.1    Haley Jr, E.C.2    Kassell, N.F.3
  • 50
    • 1642346885 scopus 로고    scopus 로고
    • Subarachnoid hemmorhage
    • Manno EM. Subarachnoid hemmorhage. Neurol Clin 2004;22:347-366.
    • (2004) Neurol Clin , vol.22 , pp. 347-366
    • Manno, E.M.1
  • 51
    • 0036318246 scopus 로고    scopus 로고
    • Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: Caspase activation and oxidative stress
    • Wang X, Mori T, Sumii T, et al. Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress. Stroke 2002;33: 1882-1888.
    • (2002) Stroke , vol.33 , pp. 1882-1888
    • Wang, X.1    Mori, T.2    Sumii, T.3
  • 52
    • 0142186341 scopus 로고    scopus 로고
    • Sildenafil and transient global amnesia
    • Gandolfo C, Sugo A, Del Sette M. Sildenafil and transient global amnesia. Neurol Sci 2003;24: 145-146.
    • (2003) Neurol Sci , vol.24 , pp. 145-146
    • Gandolfo, C.1    Sugo, A.2    Del Sette, M.3
  • 53
    • 0037056370 scopus 로고    scopus 로고
    • Transient global amnesia after sildenafil (Viagra) use
    • Savitz SA, Caplan LR. Transient global amnesia after sildenafil (Viagra) use. Neurology 2002;59:778.
    • (2002) Neurology , vol.59 , pp. 778
    • Savitz, S.A.1    Caplan, L.R.2
  • 54
    • 22644445908 scopus 로고    scopus 로고
    • Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: A possible association?
    • Schiefer J, Sparing R. Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: a possible association? Int J Impot Res 2005;17:383-384.
    • (2005) Int J Impot Res , vol.17 , pp. 383-384
    • Schiefer, J.1    Sparing, R.2
  • 55
    • 28344453810 scopus 로고    scopus 로고
    • Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition
    • Devan BD, Bowker JL, Duffy KB, et al. Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition. Psychopharmacology (Berl) 2006;183:439-445.
    • (2006) Psychopharmacology (Berl) , vol.183 , pp. 439-445
    • Devan, B.D.1    Bowker, J.L.2    Duffy, K.B.3
  • 56
    • 10044297395 scopus 로고    scopus 로고
    • Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats
    • Devan BD, Sierra-Mercado D Jr, Jimenez M, et al. Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats. Pharmacol Biochem Behav 2004;79: 691-699.
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 691-699
    • Devan, B.D.1    Sierra-Mercado Jr, D.2    Jimenez, M.3
  • 57
    • 17644425986 scopus 로고    scopus 로고
    • A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis
    • Fowler CJMJ, Sharief MK, Hussain IF, et al. A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis. J Neurol Neurosurg Psychiatry 2005;76:700-705.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 700-705
    • Fowler, C.J.M.J.1    Sharief, M.K.2    Hussain, I.F.3
  • 58
    • 0036990049 scopus 로고    scopus 로고
    • Sildenafil in the treatment of erectile dysfunction in elderly depressed patients with idiopathic Parkinson's disease
    • Giammusso B, Raffaele R, Vecchio I, et al. Sildenafil in the treatment of erectile dysfunction in elderly depressed patients with idiopathic Parkinson's disease. Arch Gerontol Geriatr Suppl 2002;8: 157-163.
    • (2002) Arch Gerontol Geriatr Suppl , vol.8 , pp. 157-163
    • Giammusso, B.1    Raffaele, R.2    Vecchio, I.3
  • 59
    • 0034892569 scopus 로고    scopus 로고
    • Treatment of erectile dysfunction with sildenafil citrate (Viagra) in parkinsonism due to Parkinson's disease or multiple system atrophy with observations on orthostatic hypotension
    • Hussain IF, Brady CM, Swinn MJ, et al. Treatment of erectile dysfunction with sildenafil citrate (Viagra) in parkinsonism due to Parkinson's disease or multiple system atrophy with observations on orthostatic hypotension. J Neurol Neurosurg Psychiatry 2001;71:371-374.
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 371-374
    • Hussain, I.F.1    Brady, C.M.2    Swinn, M.J.3
  • 60
    • 0021920534 scopus 로고
    • cGMP phosphodiesterase in rod and cone outer segments of the retina
    • Hurwitz RL, Ann S, Bunt-Milamall H, et al. cGMP phosphodiesterase in rod and cone outer segments of the retina. J Biol Chem 1985;260:568-573.
    • (1985) J Biol Chem , vol.260 , pp. 568-573
    • Hurwitz, R.L.1    Ann, S.2    Bunt-Milamall, H.3
  • 61
    • 0033616487 scopus 로고    scopus 로고
    • Retinal side-effects of sildenafil
    • Vobig MA, Klotz T, Staak M, et al. Retinal side-effects of sildenafil. Lancet 1999;353:375.
    • (1999) Lancet , vol.353 , pp. 375
    • Vobig, M.A.1    Klotz, T.2    Staak, M.3
  • 62
    • 0033899475 scopus 로고    scopus 로고
    • Branch retinal artery occlusion; another complication of sildenafil
    • Tripathi A, O'Donnell NP. Branch retinal artery occlusion; another complication of sildenafil. Br J Ophthalmol 2000;84:934-935.
    • (2000) Br J Ophthalmol , vol.84 , pp. 934-935
    • Tripathi, A.1    O'Donnell, N.P.2
  • 64
    • 0033616487 scopus 로고    scopus 로고
    • Retinal side-effects of sildenafil
    • Vobig MA. Retinal side-effects of sildenafil. Lancet 1999;353:1442.
    • (1999) Lancet , vol.353 , pp. 1442
    • Vobig, M.A.1
  • 65
    • 0036248385 scopus 로고    scopus 로고
    • A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration
    • Birch D, Toler SM, Swanson WH, et al. A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration. Am J Ophthalmol 2002;133: 665-672.
    • (2002) Am J Ophthalmol , vol.133 , pp. 665-672
    • Birch, D.1    Toler, S.M.2    Swanson, W.H.3
  • 66
    • 84975515519 scopus 로고    scopus 로고
    • Anterior ischemic optic neuropathy associated with viagra
    • Cunningham AV, Smith KH. Anterior ischemic optic neuropathy associated with viagra. J Neuroophthalmol 2001;21:22-25.
    • (2001) J Neuroophthalmol , vol.21 , pp. 22-25
    • Cunningham, A.V.1    Smith, K.H.2
  • 67
    • 0033966053 scopus 로고    scopus 로고
    • Sildenafil (Viagra) associated anterior ischemic optic neuropathy
    • Egan R, Pomeranz H. Sildenafil (Viagra) associated anterior ischemic optic neuropathy. Arch Ophthalmol 2000;118:291-292.
    • (2000) Arch Ophthalmol , vol.118 , pp. 291-292
    • Egan, R.1    Pomeranz, H.2
  • 68
    • 0036184812 scopus 로고    scopus 로고
    • Sildenafil-associated nonarteritic anterior ischemic optic neuropathy
    • Pomeranz HD, Smith KH, Hart WM Jr, et al. Sildenafil-associated nonarteritic anterior ischemic optic neuropathy. Ophthalmology 2002;109: 584-587.
    • (2002) Ophthalmology , vol.109 , pp. 584-587
    • Pomeranz, H.D.1    Smith, K.H.2    Hart Jr, W.M.3
  • 69
    • 33646489801 scopus 로고    scopus 로고
    • Nonarteritic anterior ischemic optic neuropathy and sildenafil
    • Fraunfelder FW, Pomeranz HD, Egan RA. Nonarteritic anterior ischemic optic neuropathy and sildenafil. Arch Ophthalmol 2006;124:733-734.
    • (2006) Arch Ophthalmol , vol.124 , pp. 733-734
    • Fraunfelder, F.W.1    Pomeranz, H.D.2    Egan, R.A.3
  • 70
    • 85047054181 scopus 로고
    • Sildenafil-associated NAION
    • author reply
    • Gandhi JS. Sildenafil-associated NAION. Ophthalmology. 2003;110:1860-1861; author reply 1861.
    • (1861) Ophthalmology , vol.110 , pp. 1860-1861
    • Gandhi, J.S.1
  • 71
    • 33645052699 scopus 로고    scopus 로고
    • Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy
    • Gorkin L, Hvidsten K, Sobel RE, et al. Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy. Int J Clin Pract 2006; 60:500-503.
    • (2006) Int J Clin Pract , vol.60 , pp. 500-503
    • Gorkin, L.1    Hvidsten, K.2    Sobel, R.E.3
  • 72
    • 17644425986 scopus 로고    scopus 로고
    • A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis
    • Fowler CJ, Miller JR, Sharief MK, et al. A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis. J Neurol Neurosurg Psychiatry 2005;76:700-705.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 700-705
    • Fowler, C.J.1    Miller, J.R.2    Sharief, M.K.3
  • 73
    • 0033048386 scopus 로고    scopus 로고
    • Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group
    • Giuliano F, Hultling C, El Masry WS, et al. Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group. Ann Neurol 1999;46:15-21.
    • (1999) Ann Neurol , vol.46 , pp. 15-21
    • Giuliano, F.1    Hultling, C.2    El Masry, W.S.3
  • 74
    • 0034022209 scopus 로고    scopus 로고
    • Sildenafil citrate (Viagra) for the treatment of erectile dysfunction in men with Parkinson's disease
    • Zesiewicz TA, Helal M, Hauser RA. Sildenafil citrate (Viagra) for the treatment of erectile dysfunction in men with Parkinson's disease. Mov Disord 2000;15: 305-308.
    • (2000) Mov Disord , vol.15 , pp. 305-308
    • Zesiewicz, T.A.1    Helal, M.2    Hauser, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.