The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects

Journal of Cerebral Blood Flow and Metabolism

Volumn 22, Issue 9, 2002, Pages 1124-1131

  Kruuse, Christina ^a   Thomsen, Lars Lykke ^a   Jacobsen, Torsten Bjørn ^a   Olesen, Jes ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cerebral artery dilatation; Cerebral blood flow; Headache; Nitric oxide; Phosphodiesterase inhibitors; Sildenafil

Indexed keywords

DIPYRIDAMOLE; LOPRINONE; NIMODIPINE; PAPAVERINE; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITOR; PLACEBO; SILDENAFIL; THEOPHYLLINE; XENON 133;

ADULT; ARTERY DIAMETER; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE MEASUREMENT; BRAIN BLOOD FLOW; BRAIN PERFUSION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOPPLER ECHOGRAPHY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HEADACHE; HEART RATE; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; MALE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; PRIORITY JOURNAL; RADIAL ARTERY; RANDOMIZED CONTROLLED TRIAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL ARTERY;

EID: 0036713960     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200209000-00010     Document Type: Article

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