A Caco-2 cell based screening method for compounds interacting with MRP2 efflux protein

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 71, Issue 2, 2009, Pages 332-338

  Siissalo, Sanna ^a   Hannukainen, Jenni ^a   Kolehmainen, Johanna ^a   Hirvonen, Jouni ^a   Kaukonen, Ann Marie ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

5(6) Carboxy 2 ,7 dichlorofluorescein; Caco 2 cell line; CDCF; Intracellular de esterification; MRP2 efflux protein; Screening method

Indexed keywords

4 AMINOHIPPURIC ACID; 5(6) CARBOXY 2',7' DICHLOROFLUORESCEIN; 5(6) CARBOXY 2',7' DICHLOROFLUORESCEIN DIACETATE; DICLOFENAC; ESTERASE; FUROSEMIDE; INDOMETACIN; MULTIDRUG RESISTANCE PROTEIN 2; PARACETAMOL; PHENOBARBITAL; PROBENECID; UNCLASSIFIED DRUG; VERAPAMIL; VERLUKAST;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL STRAIN CACO 2; DRUG ABSORPTION; DRUG DISPOSITION; DRUG SCREENING; FLUORESCENCE; HUMAN; HUMAN CELL; PASSIVE TRANSPORT; PROTEIN LOCALIZATION; SCREENING TEST;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; FLUORESCEINS; FLUORESCENT DYES; HUMANS; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PHARMACEUTICAL PREPARATIONS;

EID: 59649121121     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.08.010     Document Type: Article

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