A truncation in the aryl hydrocarbon receptor of the CRL:WI(Han) rat does not affect the developmental toxicity of TCDD

Toxicological Sciences

Volumn 107, Issue 2, 2009, Pages 512-521

  Jiang, Tao ^a   Bell, David R ^a   Clode, Sally ^b   Fan, Ming Qi ^a   Fernandes, Alwyn ^c   Foster, Paul M D ^d   Loizou, George ^e   Macnicoll, Alan ^c   Miller, Brian G ^f   Rose, Martin ^c   Tran, Lang ^f   White, Shaun ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UK   (United Kingdom)

^c CENTRAL SCIENCE LABORATORY   (United Kingdom)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e HEALTH AND SAFETY LABORATORY   (United Kingdom)

^f INSTITUTE OF OCCUPATIONAL MEDICINE   (United Kingdom)

Author keywords

Aryl hydrocarbon receptor; Developmental toxicity; Genetics; SNP; TCDD

Indexed keywords

3,7,8 TRICHLORO 2 IODODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; COMPLEMENTARY DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; LIVER DEVELOPMENT; LIVER TOXICITY; MALE; MOLECULAR CLONING; NONHUMAN; POINT MUTATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; RECEPTOR BINDING; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL HOMOLOGY; WESTERN BLOTTING; WISTAR HANNOVER RAT;

ALLELES; ANIMALS; BLOTTING, WESTERN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENVIRONMENTAL POLLUTANTS; GENOTYPE; GROWTH DISORDERS; LIGANDS; PLASMIDS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, ARYL HYDROCARBON; RECOMBINANT PROTEINS; TETRACHLORODIBENZODIOXIN;

RATTUS; RATTUS NORVEGICUS;

EID: 59149092191     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn252     Document Type: Article

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