PGC-1α induces dynamic protein interactions on the ERRα gene multi-hormone response element nucleosome in kidney cells

Biochemical Journal

Volumn 416, Issue 3, 2008, Pages 407-419

  Wang, Liangli ^a   Li, Yin ^a   Hu, Peng ^a   Teng, Christina T ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Chromatin immunoprecipitation (ChIP); Co regulator; Human kidney HK2 cell; Nucleosome; Oestrogen related receptor (ERR) and ; Peroxisome proliferator activated receptor coactivator 1 (PGC 1 )

Indexed keywords

BEFORE AND AFTER; CBP [CREB (CAMP-RESPONSE-ELEMENT-BINDING PROTEIN)-BINDING PROTEIN]; CHROMATIN IMMUNOPRECIPITATION (CHIP); CO-REGULATOR; COACTIVATOR; COACTIVATORS; COREPRESSOR; DNA-BINDING PROTEIN; DYNAMIC PROTEINS; GENE PROMOTER; HISTONE ACETYLATION; HOMOEOSTASIS; HORMONE RESPONSE; HUMAN KIDNEY; HUMAN KIDNEY HK2 CELL; KIDNEY CELLS; MASTER REGULATORS; MOLECULAR MECHANISM; NUCLEOSOME; OESTROGEN; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEIN INTERACTION; RECEPTOR-INTERACTING PROTEINS; RESPONSE ELEMENTS; RNA POLYMERASE II; SIGNALLING PATHWAYS; SMALL INTERFERING RNA; STRUCTURAL CHANGE;

BINDING ENERGY; BIOASSAY; BIOCHIPS; CYTOLOGY; FETAL MONITORING; GENES; NUCLEIC ACIDS; PROTEINS; RNA;

DYNAMIC RESPONSE;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA BINDING PROTEIN; ESTROGEN RECEPTOR; ESTROGEN RELATED RECEPTOR ALPHA; ESTROGEN RELATED RECEPTOR GAMMA; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; HISTONE H4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P300; RECEPTOR INTERACTING PROTEIN 140; RNA POLYMERASE II; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ERRALPHA ESTROGEN RELATED RECEPTOR; ERRALPHA ESTROGEN-RELATED RECEPTOR; ESRRG PROTEIN, HUMAN; HEAT SHOCK PROTEIN; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ACETYLATION; ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; GENE MAPPING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KIDNEY CELL; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; STRUCTURE ANALYSIS; ANIMAL; CELL LINE; CHEMISTRY; CHROMATIN; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; KIDNEY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

ANIMALS; BASE SEQUENCE; CELL LINE; CHROMATIN; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HOMEOSTASIS; HUMANS; KIDNEY; MOLECULAR SEQUENCE DATA; NUCLEOSOMES; PROMOTER REGIONS, GENETIC; RECEPTORS, ESTROGEN; RNA INTERFERENCE; RNA POLYMERASE II; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EID: 58949092974     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081085     Document Type: Article

References (41)

1. Giguere, V., Yang, N., Segui, P. and Evans, R. M. (1988) Identification of a new class of steroid hormone receptors. Nature 331, 91-94
2. Giguere, V. (2002) To ERR in the estrogen pathway. Trends. Endocrinol. Metab. 13, 220-225
3. Yang, N., Shigeta, H., Shi, H. and Teng, C. T. (1996) Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter. J. Biol. Chem. 271, 5795-5804
4. Sladek, R., Bader, J. A. and Giguere, V. (1997) The orphan nuclear receptor estrogen-related receptor á is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol. Cell. Biol. 17, 5400-5409
5. Johnston, S. D., Liu, X., Zuo, F., Eisenbraun, T. L., Wiley, S. R., Kraus, R. J. and Mertz, J. E. (1997) Estrogen-related receptor α 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements. Mol. Endocrinol. 11, 342-352
6. Zhang, Z., Chen, K., Shih, J. C. and Teng, C. T. (2006) Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. Mol. Endocrinol. 20, 1547-1561
7. Zhang, Z. and Teng, C. T. (2000) Estrogen receptor-related receptor α 1 interacts with coactivator and constitutively activates the estrogen response elements of the human lactoferrin gene. J. Biol. Chem. 275, 20837-20846
8. Heard, D. J., Norby, P. L., Holloway, J. and Vissing, H. (2000) Human ERRγ, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult. Mol. Endocrinol. 14, 382-392
9. Zhang, Z. and Teng, C. T. (2007) Interplay between estrogen-related receptor α (ERRα) and γ (ERRγ) on the regulation of ERRα gene expression. Mol. Cell. Endocrinol. 264, 128-141
10. Huss, J. M., Kopp, R. P. and Kelly, D. P. (2002) Peroxisome proliferator-activated receptor coactivator-1α (PGC-1α) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and -γ. Identification of novel leucine-rich interaction motif within PGC-1α. J. Biol. Chem. 277, 40265-40274
11. Laganiere, J., Tremblay, G. B., Dufour, C. R., Giroux, S., Rousseau, F. and Giguere, V. (2004) A polymorphic autoregulatory hormone response element in the human estrogen-related receptor α (ERRα) promoter dictates peroxisome proliferator-activated receptor γ coactivator-1α control of ERRα expression. J. Biol. Chem. 279, 18504-18510
12. Mootha, V. K., Handschin, C., Arlow, D., Xie, X., St Pierre, J., Sihag, S., Yang, W., Altshuler, D., Puigserver, P., Patterson, N. et al. (2004) Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc. Natl. Acad. Sci. U.S.A. 101, 6570-6575
13. Schreiber, S. N., Knutti, D., Brogli, K., Uhlmann, T. and Kralli, A. (2003) The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor α (ERRα). J. Biol. Chem. 278, 9013-9018
14. Knutti, D. and Kralli, A. (2001) PGC-1, a versatile coactivator. Trends Endocrinol. Metab. 12, 360-365
15. Puigserver, P. and Spiegelman, B. M. (2003) Peroxisome proliferator-activated receptor-γ coactivator 1 α (PGC-1 α): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90
16. Baar, K., Wende, A. R., Jones, T. E., Marison, M., Nolte, L. A., Chen, M., Kelly, D. P. and Holloszy, J. O. (2002) Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 16, 1879-1886
17. Ichida, M., Nemoto, S. and Finkel, T. (2002) Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α). J. Biol. Chem. 277, 50991-50995
18. Cartoni, R., Leger, B., Hock, M. B., Praz, M., Crettenand, A., Pich, S., Ziltener, J. L., Luthi, F., Deriaz, O., Zorzano, A. et al. (2005) Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise. J. Physiol. 567, 349-358
19. Kim, M. S., Shigenaga, J. K., Moser, A. H., Feingold, K. R. and Grunfeld, C. (2005) Suppression of estrogen-related receptor α and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response. J. Lipid Res. 46, 2282-2288
20. Hu, P., Kinyamu, H. K., Wang, L., Martin, J., Archer, T. K. and Teng, C. (2008) Estrogen induces estrogen-related receptor α gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells. J. Biol. Chem. 283, 6752-6763
21. Liu, D., Zhang, Z. and Teng, C. T. (2005) Estrogen-related receptor-γ and peroxisome proliferator-activated receptor-γ coactivator-1α regulate estrogen-related receptor-α gene expression via a conserved multi-hormone response element. J. Mol. Endocrinol. 34, 473-487
22. Metivier, R., Penot, G., Hubner, M. R., Reid, G., Brand, H., Kos, M. and Gannon, F. (2003) Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115, 751-763
23. Shang, Y., Hu, X., DiRenzo, J., Lazar, M. A. and Brown, M. (2000) Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103, 843-852
24. Wang, Q., Carroll, J. S. and Brown, M. (2005) Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Mol. Cell 19, 631-642
25. Kang, Z., Pirskanen, A., Janne, O. A. and Palvimo, J. J. (2002) Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex. J. Biol. Chem. 277, 48366-48371
26. Vaisanen, S., Dunlop, T. W., Sinkkonen, L., Frank, C. and Carlberg, C. (2005) Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1α,25-dihydroxyvitamin D3. J. Mol. Biol. 350, 65-77
27. Shigeta, H., Zuo, W., Yang, N., DiAugustine, R. and Teng, C. T. (1997) The mouse estrogen receptor-related orphan receptor α1: molecular cloning and estrogen responsiveness. J. Mol. Endocrinol. 19, 299-309
28. Archer, T. K., Cordingley, M. G., Wolford, R. G. and Hager, G. L. (1991) Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter. Mol. Cell. Biol. 11, 688-698
29. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
30. Workman, J. L. and Kingston, R. E. (1998) Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67, 545-579
31. Calestagne-Morelli, A. and Ausio, J. (2006) Long-range histone acetylation: biological significance, structural implications, and mechanisms. Biochem. Cell Biol. 84, 518-527
32. Fukuda, H., Sano, N., Muto, S. and Horikoshi, M. (2006) Simple histone acetylation plays a complex role in the regulation of gene expression. Brief. Funct. Genomic. Proteomic. 5, 190-208
33. O'Neill, L. P. and Turner, B. M. (2003) Immunoprecipitation of native chromatin: NChIP. Methods 31, 76-82
34. Liu, D., Zhang, Z., Gladwell, W. and Teng, C. T. (2003) Estrogen stimulates estrogen-related receptor α gene expression through conserved hormone response elements. Endocrinology 144, 4894-4904
35. Dufour, C. R., Wilson, B. J., Huss, J. M., Kelly, D. P., Alaynick, W. A., Downes, M., Evans, R. M., Blanchette, M. and Giguere, V. (2007) Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRα and γ. Cell Metab. 5, 345-356
36. Struhl, K. (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12, 599-606
37. Li, X., Wong, J., Tsai, S. Y., Tsai, M. J. and O'Malley, B. W. (2003) Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol. Cell. Biol. 23, 3763-3773
38. Sandoval, J., Rodriguez, J. L., Tur, G., Serviddio, G., Pereda, J., Boukaba, A., Sastre, J., Torres, L., Franco, L. and Lopez-Rodas, G. (2004) RNAPol-ChIP: a novel application of chromatin immunoprecipitation to the analysis of real-time gene transcription. Nucleic Acids Res. 32, e88
39. Proudfoot, N. J., Furger, A. and Dye, M. J. (2002) Integrating mRNA processing with transcription. Cell 108, 501-512
40. Palancade, B. and Bensaude, O. (2003) Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation. Eur. J. Biochem. 270, 3859-3870
41. Meinhart, A., Kamenski, T., Hoeppner, S., Baumli, S. and Cramer, P. (2005) A structural perspective of CTD function. Genes Dev. 19, 1401-1415