Fos expression in hypocretinergic neurons in C57B1/6 male and female mice after long-term consumption of high fat diet

Endocrine Regulations

Volumn 42, Issue 1, 2008, Pages 137-146

  Pirnik, Zdeno ^a   Bundzikova, Jana ^a   Mikkelsen, Jens D ^b   Zelezna, Blanka ^b   Maletinska, Lenka ^c   Kiss, Alexander ^a  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^b NEUROSEARCH A S   (Denmark)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Fos; High fat diet; Hypocretin neurons; Lateral hypothalamus; Male and female c57b1 6 mice

Indexed keywords

AVIDIN; BIOTIN; DIAMINOBENZIDINE; NICKEL CHLORIDE; OREXIN; PEROXIDASE; PROTEIN FOS; NEUROPEPTIDE; OREXINS; PROTEIN C FOS; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY FAT; BODY WEIGHT; BRAIN; CONTROLLED STUDY; FEMALE; LATERAL HYPOTHALAMUS; LIPID DIET; MALE; MICROSCOPY; MOUSE; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; SEX DIFFERENCE; ADIPOSE TISSUE; ANIMAL; ATHEROGENIC DIET; BIOLOGICAL MODEL; C57BL MOUSE; DRUG EFFECT; EATING; FAT INTAKE; METABOLISM; PHYSIOLOGY; SEXUAL DEVELOPMENT; TIME; WEIGHT GAIN;

ADIPOSE TISSUE; ANIMALS; BODY WEIGHT; DIET, ATHEROGENIC; DIETARY FATS; EATING; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NEURONS; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-FOS; SEX CHARACTERISTICS; TIME FACTORS; WEIGHT GAIN;

EID: 58849138433     PISSN: 12100668     EISSN: 13360329     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. ANTUNES VR, BRAILOIU GC, KWOK EH, SCRUGGS P, DUN NJ: Orexins/hypocretins excite rat sympathetic preganglionic neurons in vivo and invitro. Am J Physiol Regul Integr Comp Physiol 281, R1801-R1807, 2001
2. BALDO BA, DANIEL RA, BERRIDGE CW, KELLEY AE: Overlapping distributions of orexin/hypocretin and dopamine-betahydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress. J Comp Neurol 464, 220-237, 2003
3. BAYER L, COLARD C, NGUYEN NU, RISOLD PY, FELLMANN D, GRIFFOND B: Alteration of the expression of the hypocretin (orexin) gene by 2-deoxyglucose in the rat lateral hypothalamic area. Neuroreport 11, 531-533, 2000
4. BURDAKOV D, ALEXOPOULOS H: Metabolic state signalling through central hypocretin/orexin neurons. J. Cell Mol Med 9, 795-803, 2005
5. CAI XJ, EVANS ML, LISTER CA, LESLIE RA, ARCH JR, WILSON S, WILLIAMS G: Hypoglycemia activates orexin neurons and selectively indreases hypothalamic orexin-B levels: responses inhibited by feeding and possibly mediated by the nucleus of the solitary tract. Diabetes 50, 105-112, 2001
6. CHANG GQ, KARATAYEV O, DAVYDOVA Z, LEIBOWITZ SF: Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus. Endocrinology 145, 3904-3912, 2004
7. CIRIELLO J, MCMURRAY JC, BABIC T, DE OLIVEIRA CV: Collateral axonal projections from hypothalamic hypocretin neurons to cardiovascular sites in nucleus ambiguus and nucleus tractus solitarius. Brain Res 991, 133-141, 2003
8. CUTLER DJ, MORRIS R, SHERIDHAR V, WATTAM TA, HOLMES SS, PATEL S, ARCH JR, WILSON S, BUCKINGHAM RE, EVANS ML, LESLIE RA, WILLIAMS G: Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord. Peptides 20, 1455-1470, 1999
9. D'ANNA KL, GAMMIE SC: Hypocretin-1 dose-dependently modulates maternal behaviour in mice. J Neuroendocrinol 18, 553-566, 2006
10. DATE Y, UETA Y, YAMASHITA H, YAMAGUCHI H, MATSUKURA S, KANGAWA K, SAKURAI T, YANAGISAWA M, NAKAZATO M: Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci USA 96, 748-753, 1999
11. DE LECEA L, KILDUFF TS, PEYRON C, GAO X, FOYE PE, DANIELSON PE, FUKUHARA C, BATTENBERG EL, GAUTVIK VT, BARTLETT FS, 2ND FRANKEL WN, VAN DEN POL AN, BLOOM FE, GAUTVIK KM, SUTCLIFFE JG: The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95, 322-327, 1998
12. DE LECEA L, SUTCLIFFE JG: The hypocretins and sleep. FEBS J 272, 5675-5688, 2005
13. DIANO S, HORVATH B, URBANSKI HF, SOTONYI P, HORVATH TL: Fasting activates the nonhuman primate hypocretin (orexin) system and its postsynaptic targets. Endocrinology 144, 3774-3778, 2003
14. DYER CJ, TOUCHETTE KJ, CARROLL JA, ALLEE GL, MATTERI RL: Cloning of porcine prepro-orexin cDNA and effects of an intramuscular injection of synthetic porcine orexin-B on feed intake in young pigs. Domest Anim Endocrinol 16, 145-148, 1999
15. EDWARDS CM, ABUSNANA S, SUNTER D, MURPHY KG, GHATEI MA, BLOOM SR: The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin. J Endocrinol 160, 7-12, 1999
16. ESTABROOKE IV, MCCARTHY MT, KO E, CHOU TC, CHEMELLI RM, YANAGISAWA M, SAPER CB, SCAMMELL TE: Fos expression in orexin neurons varies with behavioral state. J Neurosci 21, 1656-1662, 2001
17. FARADAY MM, BLAKEMAN KH, GRUNBERG NE: Strain and sex alter effects of stress and nicotine on feeding, body weight, and HPA axis hormones. Pharmacol Biochem Behav 80, 577-589, 2005
18. FRANKIN K, PAXINOS TG: The mouse brain in stereotaxic coordinates. New York: Academic Press. p. 216, 1997
19. GENTRY RT, WADE GN: Androgenic control of food intake and body weight in male rats. J Comp Physiol Psychol 90, 18-25, 1976
20. GRIFFOND B, RISOLD PY, JACQUEMARD C, COLARD C, FELLMAN D: Insulin-induced hypoglycemia increases preprohypocretin (orexin) mRNA in the rat lateral hypothalami area. Neurosci Lett 5, 77-80, 1999
21. HARRIS GC, ASTON-JONES G: Arousal and reward: a dichotomy in orexin function. Trends Neurosci 29, 571-577, 2006
22. HINOJOSA-LABORDE C, CHAPA I, LANGE D, HAYWOOD JR: Gender differences in sympathetic nervous system regulation. Clin Exp Pharmacol Physiol 26, 122-126, 1999
23. IDA T, NAKAHARA K, MURAKAMI T, HANADA R, NAKAZATO M, MURAKAMI N: Possible involvement of orexin in the stress reaction in rats. Biochem Biophys Res Commun 270, 318-323, 2000
24. JOHREN O, NEIDERT SJ, KUMMER M, DENDORFER A, DOMINIAK P: Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats. Endocrinology 142, 3324-3331, 2001
25. KALRA S, DUBE MG, PU S, XU B, HORVATH TL, KALRA PS: Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20, 68-100, 1999
26. KISS A, PALKOVITS M, SKIRBOLL LR: Light microscopic-triple-colored immunohistochemical staining on the same vibratome section using the avidin-biotin-peroxidase complex technique. Histochemistry 88, 353-356, 1988
27. KOPECKY J, HODNY Z, ROSSMEISL M, SYROVY I, KOZAK LP: Reduction of dietary obesity in aP2-Ucp transgenic mice: physiology and adipose tissue distribution. Am J Physiol 270, 768-775, 1996
28. KUDIELKA BM, BUSKE-KIRSCHBAUM A, HELLHAMMER DH, KIRSCHBAUM C: Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: the impact of age and gender. Int J Behav Med 11, 116-121, 2004
29. LAVIANO A, MEGUID MM, GLEASON JR, YANG ZJ, RENVYLE T: Comparison of long-term feeding pattern between male and female Fischer 344 rats: influence of estrous cycle. Am J Physiol 270, 413-419, 1996
30. LENARD L, SANDOR P, HAJNAL A, JANDO G, KARADI Z, KAI Y: Sex-dependent body weight changes after iontophoretic application of kainic acid into the LH or VMH. Brain Res Bull 26, 141-148, 1991
31. LIN S, HUANG XF: Altered hypothalamic c-Fos-like immunoreactivity in diet-induced obese mice. Brain Res Bull 49, 215-219, 1999
32. LIU XH, MORRIS R, SPILLER D, WHITE M, WILLIAMS G: Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro. Diabetes 50, 2431-2437, 2001
33. MARTYNSKA L, WOLINSKA-WITORT E, CHMIELOWSKA M, BIK W, BARANOWSKA B: The physiological role of orexins. Neuro Endocrinol Lett 26, 289-292, 2005
34. MEISTER B: Control of food intake via leptin receptors in the hypothalamus. Vitam Horm 59, 265-304, 2000
35. MIKKELSEN JD, VRANG N, MROSOVSKY N: Expression of Fos in the circadian system following nonphotic stimulation. Brain Res Bull 47, 367-376, 1998
36. MIKKELSEN JD, HAUSER F, DELECEA L, SUTCLIFFE JG, KILDUFF TS, CALGARI C, PEVET P, SIMONNEAUX V: Hypocretin (orexin) in the rat pineal gland: a central transmitter with effects on noradrenaline-induced release of melatonin. Eur J Neurosci 14, 419-425, 2001
37. MOGI K, FUNABASHI T, MITSUSGIMA D, HAGIWARA H, KIMURA F: Sex difference in the response of melanin-concentrating hormone neurons in the lateral hypothalamic area to glucose, as revealed by the expression of phosphorylated cyclic adenosine 3',5'-monophosphate response element-binding protein. Endocrinology 146, 3325-3333, 2005
38. MUROYA S, FUNAHASHI H, YAMANAKA A, KOHNO D, URAMURA K, NAMBU T, SHIBAHARA M, KURAMOCHI M, TAKIGAWA M, YANAGISAWA M, SAKURAI T, SHIODA S, YADA T: Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. Eur J Neurosci 19, 1524-1534, 2004
39. NOVAK CM, ALBERS HE: Localization of hypocretin-like immunoreactivity in the brain of the diurnal rodent, Arvicanthis niloticus. J Chem Neuroanat 23, 49-58, 2002
40. QU D, LUDWIG DS, GAMMELTOFT S, PIPER M, PELLEYMOUNTER MA, CULLEN MJ, MATHES WF, PRZYPEK R, KANAREK R, MARATOS-FLIER E: A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380, 243-247, 1996
41. PEYRON C, TIGHE DK, VAN DEN POL AN, DE LECEA L, HELLER HC, SUTCLIFFE JG, KILDUFF TS: Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 18, 9996-10015, 1998
42. PRETI A: Orexins (hypocretins): their role in appetite and arousal. Curr Opin Investig Drugs 3, 1199-1206, 2002
43. Russell SH, Small CJ, Kennedy AR, Stanley SA, Seth A, Murphy KG, Taheri S, Ghatei MA, BLOOM SR: Orexin A interactions in the hypothalamo-pituitary gonadal axis. Endocrinology 142, 5294-5302, 2001
44. SAKURAI T, AMEMIYA A, ISHII M, MATSUZAKI I, CHEMELLI RM, TANAKA H, WILLIAMS SC, RICHARSON JA, KOZLOWSKI GP, WILSON S, ARCH JR, BUCKINGHAM RE, HAYNES AC, CARR SA, ANNAN RS, MCNULTY DE, LIU WS, TERRETT JA, ELSHOURBAGY NA, BERGSMA DJ, YANAGISAWA M: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92, 573-585, 1998
45. SAMSON WK, GOSNELL B, CHANG JK, RESCH ZT, MURPHY TC: Cardiovascular regulatory actions of the hypocretins in brain. Brain Res 831, 248-253, 1999
46. SAMSON WK, TAYLOR MM, FERGUSON AV: Non-sleep effects of hypocretin/orexin. Sleep Med Rev 9, 243-252, 2005
47. SARTIN JL, DYER C, MATTERI R, BUXTON D, BUONOMO F, SHORES M, BAKER J, OSBORNE JA, BRADEN T, STEELE B: Effect of intracerebroventricular orexin-B on food intake in sheep. J Anim Sci 79, 1573-1577, 2001
48. SHIMADA M, TRITOS NA, LOWELL BB, FLIER JS, MARATOS-FLIER E: Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396, 670-674, 1998
49. TAHERI S, MAHMOODI M, OPACKA-JUFFRY J, GHATEI MA, BLOOM SR: Distribution and quantification of immunoreactive orexin A in rat tissues. FEBS Lett 457, 157-161, 1999
50. TAHERI S, ZEITZER JM, MIGNOT E: The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annu Rev Neurosci 25, 283-313, 2002
51. TRIVEDI P, YU H, MACNEIL DJ, VAN DER PLOEG LH, GUAN XM: Distribution of orexin receptor mRNA in the rat brain. FEBS Lett 438, 71-75, 1998
52. WAGNER D, SALIN-PASCUAL R, GRECO MA, SHIROMANI PJ: Distribution of hypocretin-containing neurons in the lateral hypothalamus and C-fos-immunoreactive neurons in the VLPO. Sleep Res Online 3, 35-42, 2000
53. WHYTE JJ, ALEXENKO AP, DAVIS AM, ELLERSIECK MR, FOUNTAIN ED, ROSENFELD CS: Maternal diet composition alters serum steroid and free fatty acid concentrations and vaginal pH in mice. J Endocrinol 192, 75-81, 2007
54. WILLIAMS G, HARROLD JA, CUTLER DJ: The hypothalamus and the regulation of energy homeostasis: lifting the lid on a black box. Proc Nutr Soc 59, 385-396, 2000
55. WILLIAMS G, BING C, CAI XJ, HARROLD JA, KING PJ, LIU XH: The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol Behav 74, 683-701, 2001
56. WILLIE JT, CHEMELLI RM, SINTON CM, YANAGISAWA M: To eat or to sleep? Orexin in the regulation of feeding and wakefulness. Annu Rev Neurosci 24, 429-458, 2001
57. WINSKY-SOMMERER R, YAMANAKA A, DIANO S, BOROK E, ROBERTS AJ, SAKURAI T, KILDUFF TS, HORVATH TL, DE LECEA L: Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. J Neurosci 24, 11439-11448, 2004
58. WOLDBYE DP, GREISEN MH, BOLWIG TG, LARSEN PJ, MIKKELSEN JD: Prolonged induction of c-fos in neuropeptide Y and somatostatin-immunoreactive neurons of the rat dentate gyrus after electroconvulsive stimulation. Brain Res 720, 111-119, 1996
59. XIN X, STORLIEN LH, HUANG XF: Hypothalamic c-fos-like immunoreactivity in high-fat diet-induced obese and resistant mice. Brain Res Bull 52, 235-242, 2000