Sex difference in the response of melanin-concentrating hormone neurons in the lateral hypothalamic area to glucose, as revealed by the expression of phosphorylated cyclic adenosine 3′,5′-monophosphate response element-binding protein

Endocrinology

Volumn 146, Issue 8, 2005, Pages 3325-3333

  Mogi, Kazutaka ^a   Funabashi, Toshiya ^a   Mitsushima, Dai ^a   Hagiwara, Hiroko ^a   Kimura, Fukuko ^a,b  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTROGEN; GLUCOSE; MELANIN CONCENTRATING HORMONE; SODIUM CHLORIDE; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIESTRUS; DIET RESTRICTION; ESTRUS; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; GLUCOSE TRANSPORT; GONADECTOMY; HORMONE DETERMINATION; HORMONE SUBSTITUTION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPONSE TIME; SEX DIFFERENCE; TISSUE PREPARATION;

ANIMALS; BLOOD GLUCOSE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ESTRUS; FASTING; FEMALE; GLUCOSE; HYPOTHALAMIC AREA, LATERAL; HYPOTHALAMIC HORMONES; INSULIN; MALE; MELANINS; NEURONS; ORCHIECTOMY; OVARIECTOMY; PHOSPHOPROTEINS; PHOSPHORYLATION; PITUITARY HORMONES; RATS; RATS, WISTAR; SEX CHARACTERISTICS;

EID: 23044475918     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0078     Document Type: Article

References (56)

1. de Castro JM 1987 Circadian rhythms of the spontaneous meal pattern, macronutrient intake, and mood of humans. Physiol Behav 40:437-446
2. Laviano A, Meguid MM, Gleason JR, Yang ZJ, Renvyle T 1996 Comparison of long-term feeding pattern between male and female Fischer 344 rats: influence of estrous cycle. Am J Physiol 270:R413-R419
3. Dye L, Blundell JE 1997 Menstrual cycle and appetite control: implications for weight regulation. Hum Reprod 12:1142-1151
4. Eckel LA, Houpt TA, Geary N 2000 Spontaneous meal patterns in female rats with and without access to running wheels. Physiol Behav 70:397-405
5. Bell DD, Zucker I 1971 Sex differences in body weight and eating: organization and activation by gonadal hormones in the rat. Physiol Behav 7:27-34
6. Blaustein JD, Wade GN 1976 Ovarian influences on the meal patterns of female rats. Physiol Behav 17:201-208
7. Gentry RT, Wade GN 1976 Androgenic control of food intake and body weight in male rats. J Comp Physiol Psychol 90:18-25
8. Gentry RT, Wade GN 1976 Sex differences in sensitivity of food intake, body weight, and running-wheel activity to ovarian steroids in rats. J Comp Physiol Psychol 90:747-754
9. Varma M, Chai JK, Meguid MM, Laviano A, Gleason JR, Yang ZJ, Blaha V 1999 Effect of estradiol and progesterone on daily rhythm in food intake and feeding patterns in Fischer rats. Physiol Behav 68:99-107
10. Geary N 1999 Estradiol, CCK and satiation. Peptides 22:1251-1263
11. Wager-Srdar SA, Gannon M, Levine AS 1987 The effect of cholecystokinin on food intake in gonadectomized and intact rats: the influence of sex hormones. Physiol Behav 40:25-28
12. Flanagan-Cato LM, King JL, Blechman JG, O'Brien MP 1998 Estrogen reduces cholecystokinin-induced c-Fos expression in the rat brain. Neuroenedocrinology 67:384-391
13. Bittencourt JC, Presse F, Arias C, Peto C, Vaughan J, Nahon JL, Vale W, Sawchenko PE 1992 The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol 319:218-245
14. Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, Cullen MJ, Mathes WF, Przypek R, Kanarek R, Maratos-Flier E 1996 A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380:243-247
15. Rossi M, Choi SJ, O'Shea D, Miyoshi T, Ghatei MA, Bloom SR 1997 Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138:351-355
16. Allen YS, Adrian TE, Allen JM, Tatemoto K, Crow TJ, Bloom SR, Polak JM 1983 Neuropeptide Y distribution in the rat brain. Science 221:877-879
17. Clark JT, Kalra PS, Crowley WR, Kalra SP 1984 Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115:427-429
18. Stanley BG, Magdalin W, Seirafi A, Thomas WJ, Leibowitz SF 1993 The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s). Brain Res 604:304-317
19. Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG 2000 Central nervous system control of food intake. Nature 404:661-671
20. Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E 1998 Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396:670-674
21. Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E 2001 Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 107:379-386
22. Bahjaoui-Bouhaddi M, Fellmann D, Griffond B, Bugnon C 1994 Insulin treatment stimulates the rat melanin-concentrating hormone-producing neurons. Neuropeptides 27:251-258
23. Sergeyev V, Broberger C, Gorbatyuk O, Hokfelt T 2000 Effect of 2-mercaptoacetate and 2-deoxy-D-glucose administration on the expression of NPY, AGRP, POMC, MCH and hypocretin/orexin in the rat hypothalamus. Neuroreport 11:117-121
24. Erickson JC, Clegg KE, Palmiter RD 1996 Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381:415-421
25. Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M 1999 Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 98:437-451
26. Willie JT, Chemelli RM, Sinton CM, Yanagisawa M 2001 To eat or to sleep? Orexin in the regulation of feeding and wakefulness. Annu Rev Neurosci 24:429-458
27. Mystkowski P, Seeley RJ, Hahn TM, Baskin DG, Havel PJ, Matsumoto AM, Wilkinson CW, Peacock-Kinzig K, Blake KA, Schwartz MW 2000 Hypothalamic melanin-concentrating hormone and estrogen-induced weight loss. J Neurosci 20:8637-8642
28. Ji RR, Rupp F 1997 Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. J Neurosci 17:1776-1178
29. Montminy MR, Bilezikjian L 1987 Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 328:175-178
30. 2+/calmodulin- as well as cAMP-dependent protein kinase. Proc Natl Acad Sci USA 88:5061-5065
31. He D, Funabashi T, Sano A, Uemura T, Minaguchi H, Kimura F 1999 Effects of glucose and related substrates on the recovery of the electrical activity of gonadotropin-releasing hormone pulse generator which is decreased by insulin-induced hypoglycemia in the estrogen-primed ovariectomized rat. Brain Res 820:71-76
32. Mitsushima D, Tin-Tin-Win-Shwe, Kimura F 2003 Sexual dimorphism in the GABAergic control of gonadotropin release in intact rats. Neurosci Res 46:399-405
33. Steiner RA, Bremner WJ, Clifton DK 1982 Regulation of luteinizing hormone pulse frequency and amplitude by testosterone in the adult male rat. Endocrinology 111:2055-2061
34. Crace CJ, Swenne I, Milner RDG 1989 Long-term follow-up after early protein-calorie malnutrition in young rats: sex difference in glucose tolerance and serum insulin levels. Metabolism 38:933-938
35. Galipeau DM, Yao L, McNeill JH 2002 Relationship among hyperinsulinemia, insulin resistance, and hypertension is dependent on sex. Am J Phyisol 283:H562-H567
36. Mayer J 1953 Glucostatic mechanism of regulation of food intake. N Engl J Med 249:13-16
37. Bahjaoui-Bouhaddi M, Fellmann D, Bugnon C 1994 Induction of Fosimmunoreactivity in prolactin-like containing neurons of the rat lateral hypothalamus after insulin treatment. Neurosci Lett 168:11-15
38. Sheriff S, Chance WT, Fischer JE, Balasubramaniam A 1997 Neuropeptide Y treatment and food deprivation increase cyclic AMP response element-binding in rat hypothalamus. Mol Pharmacol 51:597-604
39. Gillard ER, Khan AM, Grewal RS, Mouradi B, Wolfsohn SD, Stanley BG 1998 The second messenger cAMP elicits eating by an anatomically specific action in the perifornical hypothalamus. J Neurosci 18:2646-2652
40. Yang X-J, Funabashi T, Kow L-M, Mobbs CV 2004 A glucokinase/AP-1 glucose transduction mechanism in the ventromedial hypothalamic satiety center. In: Matschinsky FM, Magnuson MA, eds. Frontiers in diabetes. Vol 16. Basel: Karger; 313-326
41. Levin BE, Dunn-Meynell AA, Routh VH 1999 Brain glucose sensing and body energy homeostasis: role in obesity and diabetes. Am J Physiol 276:R1223-R1231
42. Havel PJ 2001 Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med 226:963-977
43. Orsini JC, Armstrong DL, Wayner MJ 1992 Responses of lateral hypothalamic neurons recorded in vitro to moderate changes in glucose concentration. Brain Res Bull 29:503-505
44. Niijima A 1986 Neural control of blood glucose level. Jpn J Physiol 36:827-841
45. Muroya S, Yada T, Shioda S, Takigawa M 1999 Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. Neurosci Lett 264:113-116
46. Kakolewski JW, Cox VC, Valenstein ES 1968 Sex differences in body-weight changes following gonadectomy of rats. Psychol Rep 22:547-554
47. Rowland DL, Perrings TS, Thommes JA 1980 Comparison of androgenic effects on food intake and body weight in adult rats. Physiol Behav 24:205-209
48. Chai J-K, Blaha V, Meguid MM, Laviano A, Yang Z-J, Varma M 1999 Use of orchidectomy and testosterone replacement to explore number-to-meal size relationship in male rats. Am J Physiol 276:R1366-R1373
49. Murray JF, Baker BI, Levy A, Wilson CA 2000 The influence of gonadal steroids on pre-pro melanin-concentrating hormone mRNA in female rats. J Neuroendocrinol 12:53-59
50. Czaja JA 1984 Sex differences in the activational effects of gonadal hormones on food intake and body weight. Physiol Behav 33:553-558
51. Sandoval DA, Ertl AC, Richardson A, Tate DB, Davis SN 2003 Estrogen blunts neuroendocrine and metabolic responses to hypoglycemia. Diabetes 52:1749-1755
52. Adams JM, Legan SJ, Ott CE, Jackson BA 2005 Modulation of hypoglycemia-induced increases in plasma epinephrine by estrogen in the female rat. J Neurosci Res 79:360-367
53. Shi J, Zhang YQ, Simpkins JW 1997 Effects of 17b-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the rats. Exp Brain Res 117:200-206
54. Luine VN, Khylchevskaya RI, McEwen BS 1975 Effect of gonadal hormones in enzyme activities in brain and pituitary of male and female rats. Brain Res 86:283-292
55. Hamba H, Sokoloff L 1984 Acute administration of high doses of estrogen increases glucose utilization throughout brain. Brain Res 291:391-394
56. Wise PM 2003 Estrogens: protective or risk factors in brain function? Prog Neurobiol 69:181-191