Association of Cumulative Lead and Neurocognitive Function in an Occupational Cohort

Neuropsychology

Volumn 23, Issue 1, 2009, Pages 10-19

  Khalil, Naila ^a   Morrow, Lisa A ^b   Needleman, Herbert ^b   Talbott, Evelyn O ^a   Wilson, John W ^a   Cauley, Jane A ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

cognitive; lead; longitudinal; neuropsychology; occupational

Indexed keywords

BIOLOGICAL MARKER; LEAD;

ADULT; AGE DISTRIBUTION; AGING; ARTICLE; BODY BURDEN; COGNITION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FOLLOW UP; HEALTH HAZARD; HUMAN; LEAD BLOOD LEVEL; MALE; NEUROPSYCHOLOGY; NEUROTOXICITY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PREDICTION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; SCORING SYSTEM; TASK PERFORMANCE; TIBIA; VULNERABLE POPULATION; WORKER;

ADOLESCENT; ADULT; BONE AND BONES; COGNITION DISORDERS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; HUMANS; LEAD; LEAD POISONING, NERVOUS SYSTEM, ADULT; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OCCUPATIONAL EXPOSURE; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 58749102441     PISSN: 08944105     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0013757     Document Type: Article

References (49)

1. Adult blood lead epidemiology and surveillance-United States, 2003-2004. Morbidity and Mortality Weekly Report 55 (2006, August 18) 876-879
2. Air quality criteria for lead (Final) (EPA/600/R-05/144aF-bF) (2006), U.S. Environmental Protection Agency, Washington, DC
3. Aro A.C., Todd A.C., Amarasiriwardena C., and Hu H. Improvements in the calibration of 109Cd K x-ray fluorescence systems for measuring bone lead in vivo. Physics in Medicine and Biology 39 (1994) 2263-2271
4. Bleecker M.L., Lindgren K.N., and Ford D.P. Differential contribution of current and cumulative indices of lead dose to neuropsychological performance by age. Neurology 48 (1997) 639-645
5. Brito J.A., McNeill F.E., Webber C.E., and Chettle D.R. Grid search: An innovative method for the estimation of the rates of lead exchange between body compartments. Journal of Environmental Monitoring 7 (2005) 241-247
6. Brito J.A., McNeill F.E., Webber C.E., Wells S., Richard N., Carvalho M.L., et al. Evaluation of a novel structural model to describe the endogenous release of lead from bone. Journal of Environmental Monitoring 4 (2002) 194-201
7. Chang W., Chen J., Wei Q.Y., and Chen X.M. Effects of Brn-3a protein and RNA expression in rat brain following low-level lead exposure during development on spatial learning and memory. Toxicology Letters 164 (2006) 63-70
8. Chettle D.R. Three decades of in vivo x-ray fluorescence of lead in bone. X-Ray Spectrometry 34 (2005) 446-450
9. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. (1988), Erlbaum, Hillsdale, NJ
10. Denburg N.L., Tranel D., and Bechara A. The ability to decide advantageously declines prematurely in some normal older persons. Neuropsychologia 43 (2005) 1099-1106
11. Dorsey C.D., Lee B.K., Bolla K.I., Weaver V.M., Lee S.S., Lee G.S., et al. Comparison of patella lead with blood lead and tibia lead and their associations with neurobehavioral test scores. Journal of Occupational and Environmental Medicine 48 (2006) 489-496
12. Fein G., McGillivray S., and Finn P. Older adults make less advantageous decisions than younger adults: Cognitive and psychological correlates. Journal of the International Neuropsychological Society 13 (2007) 480-489
13. Ganellin C.R., Bishop P.B., Bambal R.B., Chan S.M., Law J.K., Marabout B., et al. Inhibitors of tripeptidyl peptidase II. 2: Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: A strategy for the design of peptidase inhibitors. Journal of Medicinal Chemistry 43 (2000) 664-674
14. Gerhardsson L., Attewell R., Chettle D.R., Englyst V., Lundstrom N.G., Nordberg G.F., et al. In vivo measurements of lead in bone in long-term exposed lead smelter workers. Archives of Environmental Health 48 (1993) 147-156
15. Glenn B.S., Bandeen-Roche K., Lee B.K., Weaver V.M., Todd A.C., and Schwartz B.S. Changes in systolic blood pressure associated with lead in blood and bone. Epidemiology 17 (2006) 538-544
16. Glenn B.S., Stewart W.F., Links J.M., Todd A.C., and Schwartz B.S. The longitudinal association of lead with blood pressure. Epidemiology 14 (2003) 30-36
17. Heidmets L.T., Zharkovsky T., Jurgenson M., Jaako-Movits K., and Zharkovsky A. Early post-natal, low-level lead exposure increases the number of PSA-NCAM expressing cells in the dentate gyrus of adult rat hippocampus. Neurotoxicology 27 (2006) 39-43
18. Hu H., Aro A., and Rotnitzky A. Bone lead measured by X-ray fluorescence: Epidemiologic methods. Environmental Health Perspectives 103 Suppl. 1 (1995) 105-110
19. Hu H., Milder F.L., and Burger D.E. X-ray fluorescence measurements of lead burden in subjects with low-level community lead exposure. Archives of Environmental Health 45 (1990) 335-341
20. Hu H., Milder F.L., and Burger D.E. The use of K X-ray fluorescence for measuring lead burden in epidemiological studies: High and low lead burdens and measurement uncertainty. Environmental Health Perspectives 94 (1991) 107-110
21. Hu H., Pepper L., and Goldman R. Effect of repeated occupational exposure to lead, cessation of exposure, and chelation on levels of lead in bone. American Journal of Industrial Medicine 20 (1991) 723-735
22. Hu H., Shih R., Rothenberg S., and Schwartz B.S. The epidemiology of lead toxicity in adults: Measuring dose and consideration of other methodologic issues. Environmental Health Perspectives 115 (2007) 455-462
23. Hwang K.Y., Lee B.K., Bressler J.P., Bolla K.I., Stewart W.F., and Schwartz B.S. Protein kinase C activity and the relations between blood lead and neurobehavioral function in lead workers. Environmental Health Perspectives 110 (2002) 133-138
24. Lead. 29 C.F.R § 1910.1025. (2001). Retrieved April 25, 2008, from http://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=STANDARDS&p_id=10030
25. Lee B.K., Ahn K.D., Lee S.S., Lee G.S., Kim Y.B., and Schwartz B.S. A comparison of different lead biomarkers in their associations with lead-related symptoms. International Archives of Occupational and Environmental Health 73 (2000) 298-304
26. Li M.J., Liu Y.Z., Liu Y.X., Ge Y., and Zou W. [Brain impairment induced by oral intake of lead and its effects on expression of Hoxa9 Gen in rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 24 (2006) 591-593
27. Links J.M., Schwartz B.S., Simon D., Bandeen-Roche K., and Stewart W.F. Characterization of toxicokinetics and toxicodynamics with linear systems theory: Application to lead-associated cognitive decline. Environmental Health Perspectives 109 (2001) 361-368
28. Mandelbaum D. Effects of chronic lead exposure on 1H MRS of hippocampus and frontal lobes in children. Neurology 66 (2006) 614
29. Nawrot T.S., Thijs L., Den Hond E.M., Roels H.A., and Staessen J.A. An epidemiological re-appraisal of the association between blood pressure and blood lead: A meta-analysis. Journal of Human Hypertension 16 (2002) 123-131
30. Nilson L.N., Sallsten G., Hagberg S., Backman L., and Barregard L. Influence of solvent exposure and aging on cognitive functioning: An 18 year follow up of formerly exposed floor layers and their controls. Occupational and Environmental Medicine 59 (2002) 49-57
31. Parkinson D.K., Ryan C., Bromet E.J., and Connell M.M. A psychiatric epidemiologic study of occupational lead exposure. American Journal of Epidemiology 123 (1986) 261-269
32. Payton M., Riggs K.M., Spiro III A., Weiss S.T., and Hu H. Relations of bone and blood lead to cognitive function: The VA Normative Aging Study. Neurotoxicology and Teratology 20 (1998) 19-27
33. Ryan C., and Butters N. Learning and memory impairments in young and old alcoholics: Evidence for the premature aging hypothesis. Alcoholism: Clinical and Experimental Research 4 (1981) 288-293
34. Ryan C.M., Morrow L.A., Bromet E.J., and Parkinson D.K. Assessment of neuropsychological dysfunction in the workplace: Normative data from the Pittsburgh Occupational Exposures Test Battery. Journal of Clinical and Experimental Neuropsychology 9 (1987) 665-679
35. Ryan C.M., Morrow L., Parkinson D., and Bromet E. Low level lead exposure and neuropsychological functioning in blue collar males. International Journal of Neuroscience 36 1-2 (1987) 29-39
36. Schafer J.H., Glass T.A., Bolla K.I., Mintz M., Jedlicka A.E., and Schwartz B.S. Homocysteine and cognitive function in a population-based study of older adults. Journal of the American Geriatrics Society 53 (2005) 381-388
37. Schafer J.H., Glass T.A., Bressler J., Todd A.C., and Schwartz B.S. Blood lead is a predictor of homocysteine levels in a population-based study of older adults. Environmental Health Perspectives 113 (2005) 31-35
38. Schwartz B.S., Lee B.K., Bandeen-Roche K., Stewart W., Bolla K., Links J., et al. Occupational lead exposure and longitudinal decline in neurobehavioral test scores. Epidemiology 16 (2005) 106-113
39. Schwartz B.S., and Stewart W.F. Lead and cognitive function in adults: A questions and answers approach to a review of the evidence for cause, treatment, and prevention. International Review of Psychiatry 19 (2007) 671-692
40. Schwartz B.S., Stewart W.F., Bolla K.I., Simon P.D., Bandeen-Roche K., Gordon P.B., et al. Past adult lead exposure is associated with longitudinal decline in cognitive function. Neurology 55 (2000) 1144-1150
41. Shih R.A., Hu H., Weisskopf M.G., and Schwartz B.S. Cumulative lead dose and cognitive function in adults: A review of studies that measured both blood lead and bone lead. Environmental Health Perspectives 115 (2007) 483-492
42. Stewart W.F., and Schwartz B.S. Effects of lead on the adult brain: A 15-year exploration. American Journal of Industrial Medicine 50 (2007) 729-739
43. Stewart W.F., Schwartz B.S., Davatzikos C., Shen D., Liu D., Wu X., et al. Past adult lead exposure is linked to neurodegeneration measured by brain MRI. Neurology 66 (2006) 1476-1484
44. Stewart W.F., Schwartz B.S., Simon D., Bolla K.I., Todd A.C., and Links J. Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. Neurology 52 (1999) 1610-1617
45. Struzynska L., Walski M., Gadamski R., Dabrowska-Bouta B., and Rafalowska U. Lead-induced abnormalities in blood-brain barrier permeability in experimental chronic toxicity. Molecular and Chemical Neuropathology 31 (1997) 207-224
46. Todd A.C., and Chettle D.R. In vivo X-ray fluorescence of lead in bone: Review and current issues. Environmental Health Perspectives 102 (1994) 172-177
47. Wechsler D. A standardized memory scale for clinical use. Journal of Psychology 19 (1945) 87-95 Psychological Corporation
48. Weisskopf M.G., and Myers G. Cumulative effect of lead on cognition: Is bone more revealing than blood?. Neurology 67 (2006) 1536-1537
49. Weisskopf M.G., Wright R.O., Schwartz J., Spiro III A., Sparrow D., Aro A., et al. Cumulative lead exposure and prospective change in cognition among elderly men: The VA Normative Aging Study. American Journal of Epidemiology 160 (2004) 1184-1193