Early post-natal, low-level lead exposure increases the number of PSA-NCAM expressing cells in the dentate gyrus of adult rat hippocampus

NeuroToxicology

Volumn 27, Issue 1, 2006, Pages 39-43

  Heidmets, Lenne Triin ^a   Zharkovsky, Tamara ^a   Jurgenson, Monika ^a   Jaako Movits, Kulli ^a   Zharkovsky, Alexander ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

Dentate gyms; Post natal lead exposure; PSA NCAM expressing cells

Indexed keywords

BIOLOGICAL MARKER; CALBINDIN; GLIAL FIBRILLARY ACIDIC PROTEIN; LEAD ACETATE; NERVE CELL ADHESION MOLECULE; POLYSIALIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENTATE GYRUS; ENVIRONMENTAL EXPOSURE; FEMALE; GLIA CELL; HIPPOCAMPUS; LEAD BLOOD LEVEL; LEARNING DISORDER; MEMORY DISORDER; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; WEANING;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL COUNT; DENTATE GYRUS; IMMUNOHISTOCHEMISTRY; LEAD; NEURAL CELL ADHESION MOLECULE L1; NEURONS; RATS; RATS, WISTAR; SIALIC ACIDS; TIME FACTORS; TUBULIN;

ANIMALIA; RATTUS NORVEGICUS;

EID: 28544437014     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2005.05.015     Document Type: Article

References (32)

1. J. Altman, and G.D. Das Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats J Comp Neurol 124 1965 319 335
2. T. Arendt Alzheimer's disease as a loss of differentiation control in a subset of neurons that retain immature features in the adult brain Neurobiol Aging 21 2000 783 796
3. K.C. Breen, and C.M. Regan Lead stimulates Golgi sialyltransferase at times coincident with the embryonic to adult conversion of the neural cell adhesion molecule (N-CAM) Toxicology 49 1988 71 76
4. J.L. Bruses, and U. Rutishauser Roles, regulation, and mechanism of polysialic acid function during neural development Biochimie 83 2001 635 643
5. G.R. Cookman, W. King, and C.M. Regan Chronic low-level lead exposure impairs embryonic to adult conversion of the neural cell adhesion molecule J Neurochem 49 1987 399 403
6. G.R. Cookman, and C.M. Regan Studies of the antiproliferative action of inorganic lead in relation to the phases of the rat glial cell cycle Toxic in vitro 5 1991 127 132
7. H. Cremer, G. Chazal, P.M. Lledo, G. Rougon, M.F. Montaron, and W. Mayo PSA-NCAM: an important regulator of hippocampal plasticity Int J Dev Neurosci 18 2000 213 220
8. K.L. Crossin, and L.A. Krushel Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily Dev Dyn 218 2000 260 279
9. P. Doherty, and F.S. Walsh CAM-FGF receptor interactions: a model for axonal growth Mol Cell Neurosci 8 1996 99 111
10. G.M. Edelman, and C.M. Chuong Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice Proc Natl Acad Sci 79 1982 7036 7040
11. G.M. Edelman Modulation of cell adhesion during induction, histogenesis, and perinatal development of the nervous system Ann Rev Neurosci 7 1984 339 377
12. G.M. Edelman Cell adhesion molecules in the regulation of animal form and tissue pattern Ann Rev Cell Biol 2 1986 81 116
13. E. Gould, and P. Tanapat Lesion-induced proliferation of neuronal progenitors in the dentate gyrus of the adult rat Neuroscience 80 1997 427 436
14. Jaako-Movits K, Zharkovsky T, Romantchik O, Merisalu E, Heidmets L-T, Zharkovsky A. Developmental lead exposure impairs contextual fear conditioning and reduces adult hippocampal neurogenesis in the rat brain. Int J Devel Neurosci 2005; in press.
15. J.Z. Kiss, and G. Rougon Cell biology of polysialic acid Curr Opin Neurobiol. 7 1997 640 646
16. T.I. Lidsky, and J.S. Schneider Lead neurotoxicity in children: basic mechanisms and clinical correlates Brain 126 2003 5 19
17. M. Mackowiak, A. Chocyk, K. Markowicz-Kula, and K. Wedzony Neurogenesis in the adult Pol J Pharmacol 56 2004 673 687
18. T.M. Madsen, P.E. Kristjansen, T.G. Bolwig, and G. Wortwein Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat Neuroscience 119 2003 635 642
19. C.S.K. Mayanil, D. George, B. Mania-Farnell, C.L. Bremer, D.G. McLone, and E.G. Bremer Overexpression of murine Pax3 increases NCAM polysialylation in a human medulloblastoma cell line J Biol Chem 275 2000 23259 23266
20. D. Muller, Z. Djebbara-Hannas, P. Jourdain, L. Vutskits, P. Durbec, and G. Rougon Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus Proc Natl Acad Sci 97 2000 4315 4320
21. K.J. Murphy, G.B. Fox, J. Kelly, and C.M. Regan Influence of toxicants on neural cell adhesion molecule-mediated neuroplasticity in the developing and adult animal: persistent effects of chronic perinatal low-level lead exposure Toxicol Lett 82-83 1995 271 276
22. K.J. Murphy, and C.M. Regan Low-level lead exposure in the early postnatal period results in persisting neuroplastic deficits associated with memory consolidation J Neurochem 72 1999 2099 2104
23. J. Nacher, D.R. Rosell, G. Alonso-Llosa, and B.S. McEwen NMDA receptor antagonist treatment induces a long-lasting increase in the number of proliferating cells, PSA-NCAM-immunoreactive granule neurons and radial glia in the adult rat dentate gyrus Eur J Neurosci 13 2001 512 520
24. H.L. Needleman, and C.A. Gatsonis Low-level lead exposure and the IQ of children. A meta-analysis of modern studies JAMA 263 1990 673 678
25. C.M. Regan, and K. Keegan Neuroteratological consequences of chronic low-level lead exposure Dev Pharmacol Ther 15 1990 189 195
26. U. Rutishauser Polysialic acid and the regulation of cell interactions Curr Opin Cell Biol 8 1996 679 684
27. J.S. Schneider, D.W. Anderson, T.V. Wade, M.G. Smith, P. Leibrandt, and L. Zuck Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure Neurotoxicology 26 2005 141 145
28. T. Seki, and Y. Arai Distribution and possible roles of the highly polysialylated neural cell adhesion molecule (NCAM-H) in the developing and adult central nervous system Neurosci Res 17 1993 265 290
29. T. Seki Expression patterns of immature neuronal markers PSA-NCAM, CRMP-4 and NeuroD in the hippocampus of young adult and aged rodents J Neurosci Res 70 2002 327 334
30. M.J. West New stereological methods for counting neurons Neurobiol Aging 14 1993 275 285
31. G. Winneke, A. Brockhaus, and R. Baltissen Neurobehavioral and systemic effects of long term blood lead-elevation in rats. I. Discrimination learning and open field-behavior Arch Toxicol 4 1977 247 263
32. T. Zharkovsky, A. Kaasik, K. Jaako, and A. Zharkovsky Neurodegeneration and production of the new cells in the dentate gyrus of juvenile rat hippocampus after a single administration of ethanol Brain Res 978 2003 115 123