Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: A strategy for the design of peptidase inhibitors

Journal of Medicinal Chemistry

Volumn 43, Issue 4, 2000, Pages 664-674

  Ganellin, C Robin ^a   Bishop, Paul B ^a   Bambal, Ramesh B ^a   Chan, Suzanne M T ^a   Law, James K ^a   Marabout, Benoit ^a   Luthra, Pratibha Mehta ^a   Moore, Andrew N J ^a   Peschard, Olivier ^a   Bourgeat, Pierre ^b   Rose, Christiane ^b   Vargas, Froylan ^b   Schwartz, Jean Charles ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CENTRE PAUL BROCA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTABINDIDE; CHOLECYSTOKININ OCTAPEPTIDE; COUMARIN DERIVATIVE; DIPEPTIDE; ENZYME INHIBITOR; PEPTIDASE; TRIPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING SITE; DRUG DESIGN; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RAT;

ANIMALS; CEREBRAL CORTEX; DIPEPTIDES; DRUG DESIGN; OLIGOPEPTIDES; RATS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SINCALIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033996196     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990226g     Document Type: Article

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