Comparison of patella lead with blood lead and tibia lead and their associations with neurobehavioral test scores

Journal of Occupational and Environmental Medicine

Volumn 48, Issue 5, 2006, Pages 489-496

  Dorsey, Carrie D ^a,b   Lee, Byung Kook ^c   Bolla, Karen I ^b   Weaver, Virginia M ^a,b   Lee, Sung Soo ^c   Lee, Gap Soo ^c   Todd, Andrew C ^d   Shi, Weiping ^e   Schwartz, Brian S ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Soonchunhyang University   (South Korea)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e College of Medicine ^*

Author keywords

[No Author keywords available]

Indexed keywords

LEAD;

ADULT; ARTICLE; COGNITION; CONTROLLED STUDY; DEPRESSION; DEXTERITY; HUMAN; INDUSTRIAL WORKER; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; METAL INDUSTRY; MOTOR PERFORMANCE; NEUROPSYCHOLOGICAL TEST; OCCUPATIONAL EXPOSURE; PATELLA; PERIPHERAL NERVOUS SYSTEM; PREVALENCE; TIBIA; TISSUE LEVEL; TRABECULAR BONE; VIBRATION SENSE;

ADULT; AGED; BLOOD; COGNITION DISORDERS; CROSS-SECTIONAL STUDIES; HUMANS; KOREA; LEAD; LEAD POISONING, NERVOUS SYSTEM, ADULT; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PATELLA; TIBIA;

EID: 33646838600     PISSN: 10762752     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.jom.0000199678.86629.3b     Document Type: Article

References (26)

1. Rabinowitz MB. Toxicokinetics of bone lead. Environ Health Perspect. 1991;91:33-37.
2. Rabinowitz MB, Wetherill GW, Kopple JD. Kinetic analysis of lead metabolism in healthy humans. J Clin Invest. 1977;58:260-270.
3. Legget RW. An age-specific kinetic model of lead metabolism in humans. Environ Health Perspect. 1993;101:598-616.
4. Tsaih S-W, Korrick S, Schwartz J, et al. Influence of bone resorption on the mobilization of lead from bone among middle-aged and elderly men: the Normative Aging Study. Environ Health Perspect. 2001;109:995-999.
5. Hu H, Rabinowitz M, Smith D. Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms. Environ Health Perspect. 1998;106:1-8.
6. Meyer-Baron M, Seeber A. A meta-analysis for neurobehavioral results due to occupational lead exposure with blood lead concentration <70 μg/100 ml. Arch Toxicol. 2000;73:510-518.
7. Goodman M, LaVerda N, Clarke C, et al. Neurobehavioral testing in workers occupationally exposed to lead: systematic review and meta-analysis of publications. Occup Environ Med. 2002;59:217-223.
8. Balbus-Kornfeld JM, Stewart W, Bolla K, et al. Cumulative exposure to inorganic lead and neurobehavioral test performance in adults: an epidemiological review. Occup Environ Med. 1995;52:2-12.
9. Bleecker ML, Lindgren KN, Ford DP. Differential contribution of current and cumulative indices of lead dose to neuropsychological performance by age. Neurology. 1997;48:639-645.
10. Österberg K, Börjesson J, Gerhardsson L, Schütz A, Skerfving S. A neurobehavioral study of long-term occupational inorganic lead exposure. Sci Total Environ. 1997;201:39-51.
11. Hänninen H, Aitio A, Kovala T, et al. Occupational exposure to lead and neuropsychological dysfunction. Occup Environ Med. 1998;55:202-209.
12. Payton M, Riggs KM, Spiro A III, Weiss ST, Hu U. Relations of bone and blood lead to cognitive function: the VA Normative Aging Study. Neurotoxicol Teratol. 1998;20:19-27.
13. Stokes L, Letz R, Gerr F, et al. Neurotoxicity in young adults 20 years after childhood exposure to lead: the Bunker Hill experience. Occup Environ Med. 1998;55:507-515.
14. Stewart WF, Schwartz BS, Simon D, Bolla KI, Todd AC, Links J. Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. Neurology. 1999;52:1610-1617.
15. Rhodes D, Spiro A, Aro A, Hu H. Relationship of bone and blood lead levels to psychiatric symptoms: the VA Normative Aging Study. J Occup Environ Med. 2003;45:1144-1151.
16. Wright RO, Tsaih SW, Schwartz J, et al. Lead exposure biomarkers and Mini-Mental Status Exam scores in older men. Epidemiology. 2003;14:713-718.
17. Weisskopf MG, Wright RO, Schwartz J, et al. Cumulative lead exposure and prospective change in cognition among elderly men: the VA Normative Aging Study. Am J Epidemiol. 2004;160:1184-1193.
18. Schwartz BS, Lee B-K, Lee G-S, et al. Associations of blood lead, dimercapto-succinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am J Epidemiol. 2001;153:453-464.
19. Schwartz BS, Lee B-K, Bandeen-Roche K, et al. Occupational lead exposure and longitudinal decline in neurobehavioral test scores. Epidemiology. 2005;16:106-113.
20. Todd AC, Lee B-K, Lee G-S, Ahn KD, Moshier EL, Schwartz BS. Predictors of DMSA chelatable lead, tibial lead, and blood lead in 802 Korean lead workers. Occup Environ Med. 2001;58:73-80.
21. Schwartz BS, Lee B-K, Lee G-S, et al. Associations of blood lead, dimercapto-succinic acid-chelatable lead, and tibia lead with polymorphisms in the vitamin D receptor and δ-aminolevulinic acid dehydratase genes. Environ Health Perspect. 2000;108:949-954.
22. Weaver VM, Lee B-K, Ahn KD, et al. Associations of lead biomarkers with renal outcomes in Korean lead workers. Occup Environ Med. 2003;60:551-562.
23. Weaver VM, Lee B-K, Todd AC, et al. Associations of patella lead and other lead biomarkers with renal function in lead workers. J Occup Environ Med. 2005;47:235-243.
24. Fernandez FJ. Micromethod for lead determination in whole blood by atomic absorption, with use of the graphite furnace. Clin Chem. 1975;21:558-561.
25. Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc. 1979;74:829-836.
26. Hu H, Milder FL, Burger DE. The use of K x-ray fluorescence for measuring lead burden in epidemiological studies: high and low lead burdens and measurement uncertainty. Environ Health Perspect. 1991;94:107-110.