Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-α

Journal of Immunology

Volumn 181, Issue 9, 2008, Pages 5875-5884

  Uccellini, Melissa B ^a   Busconi, Liliana ^a   Green, Nathaniel M ^a   Busto, Patricia ^a   Christensen, Sean R ^b   Shlomchik, Mark J ^b   Marshak Rothstein, Ann ^a   Viglianti, Gregory A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BREAKPOINT CLUSTER REGION PROTEIN; DNA; DNA FRAGMENT; IMMUNOGLOBULIN G2A; TOLL LIKE RECEPTOR 9; AUTOANTIGEN; BACTERIAL DNA; CPG DNA, E COLI; CPG-DNA, E COLI; LYMPHOCYTE ANTIGEN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; CPG ISLAND; CROSS LINKING; DNA SEQUENCE; LYMPHOCYTE PROLIFERATION; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSGENIC MOUSE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CLONE; COMPARATIVE STUDY; DOSE RESPONSE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; AUTOANTIGENS; B-LYMPHOCYTE SUBSETS; CLONE CELLS; CPG ISLANDS; DNA, BACTERIAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; INTERFERON-ALPHA; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, B-CELL;

EID: 58749093255     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.9.5875     Document Type: Article

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