-
1
-
-
0021256125
-
Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity
-
Tokunaga, T., Yamamoto, H., Shimada, S., Abe, H., Fukuda, T., Fujisawa, Y., Furutani, Y., Yano, O., Kataoka, T. and Sudo, T. 1984. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity. J. Natl Cancer Inst. 72:955.
-
(1984)
J. Natl. Cancer Inst.
, vol.72
, pp. 955
-
-
Tokunaga, T.1
Yamamoto, H.2
Shimada, S.3
Abe, H.4
Fukuda, T.5
Fujisawa, Y.6
Furutani, Y.7
Yano, O.8
Kataoka, T.9
Sudo, T.10
-
2
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg, A. M., Yi, A. K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A. and Klinman, D. M. 1995. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374:546.
-
(1995)
Nature
, vol.374
, pp. 546
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
3
-
-
0032995849
-
Bacterial CpG DNA activates immune cells to signal infectious danger
-
Wagner, H. 1999. Bacterial CpG DNA activates immune cells to signal infectious danger. Adv. Immunol. 73:329.
-
(1999)
Adv. Immunol.
, vol.73
, pp. 329
-
-
Wagner, H.1
-
4
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg, A. M. 2002. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20:709.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 709
-
-
Krieg, A.M.1
-
6
-
-
0035109939
-
CpG-containing oligodeoxynucleotides induce TNF-alpha and IL-6 production but not degranulation from murine bone marrow-derived mast cells
-
Zhu, F. G. and Marshall, J. S. 2001. CpG-containing oligodeoxynucleotides induce TNF-alpha and IL-6 production but not degranulation from murine bone marrow-derived mast cells. J. Leukoc. Biol. 69:253.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 253
-
-
Zhu, F.G.1
Marshall, J.S.2
-
7
-
-
0035137604
-
CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes
-
Stan, A. C., Casares, S., Brumeanu, T. D., Klinman, D. M. and Bona, C. A. 2001. CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes. Eur. J. Immunol. 31:301.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 301
-
-
Stan, A.C.1
Casares, S.2
Brumeanu, T.D.3
Klinman, D.M.4
Bona, C.A.5
-
8
-
-
0034668119
-
Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response
-
Weighardt, H., Feterowski, C., Veit, M., Rump, M., Wagner, H. and Holzmann, B. 2000. Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response. J. Immunol. 165:4537.
-
(2000)
J. Immunol.
, vol.165
, pp. 4537
-
-
Weighardt, H.1
Feterowski, C.2
Veit, M.3
Rump, M.4
Wagner, H.5
Holzmann, B.6
-
9
-
-
0035255056
-
Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides
-
Schluesener, H. J., Seld, K., Deininger, M. and Schwab, J. 2001. Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides. J. Neuroimmunol. 113:89.
-
(2001)
J. Neuroimmunol.
, vol.113
, pp. 89
-
-
Schluesener, H.J.1
Seld, K.2
Deininger, M.3
Schwab, J.4
-
11
-
-
0033536013
-
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms
-
Walker, P. S., Scharton-Kersten, T., Krieg, A. M., Love-Homan, L., Rowton, E. D., Udey, M. C. and Vogel, J. C. 1999. Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc. Natl Acad. Sci. USA 96:6970.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6970
-
-
Walker, P.S.1
Scharton-Kersten, T.2
Krieg, A.M.3
Love-Homan, L.4
Rowton, E.D.5
Udey, M.C.6
Vogel, J.C.7
-
12
-
-
0033558121
-
Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria
-
Elkins, K. L., Rhinehart-Jones, T. R., Stibitz, S., Conover, J. S. and Klinman, D. M. 1999. Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J. Immunol. 162:2291.
-
(1999)
J. Immunol.
, vol.162
, pp. 2291
-
-
Elkins, K.L.1
Rhinehart-Jones, T.R.2
Stibitz, S.3
Conover, J.S.4
Klinman, D.M.5
-
13
-
-
0032168355
-
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge
-
Krieg, A. M., Love-Homan, L., Yi, A. K. and Harty, J. T. 1998. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge. J. Immunol. 161:2428.
-
(1998)
J. Immunol.
, vol.161
, pp. 2428
-
-
Krieg, A.M.1
Love-Homan, L.2
Yi, A.K.3
Harty, J.T.4
-
14
-
-
0034666740
-
h1-promoting adjuvant in immunization against Trypanosoma cruzi
-
h1-promoting adjuvant in immunization against Trypanosoma cruzi. Vaccine 19:234.
-
(2000)
Vaccine
, vol.19
, pp. 234
-
-
Corral, R.S.1
Petray, P.B.2
-
15
-
-
0035815501
-
Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89. 6P)
-
Cafaro, A., Titti, F., Fracasso, C., Maggiorella, M. T., Baroncelli, S., Caputo, A., Goletti, D., Borsetti, A., Pace, M., Fanales-Belasio, E., Ridolfi, B., Negri, D. R., Sernicola, L., Belli, R., Corrias, F,, Macchia, I., Leone, P., Michelini, Z., ten Haaft, P., Butto, S., Verani, P. and Ensoli, B. 2001. Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89. 6P). Vaccine 19:2862.
-
(2001)
Vaccine
, vol.19
, pp. 2862
-
-
Cafaro, A.1
Titti, F.2
Fracasso, C.3
Maggiorella, M.T.4
Baroncelli, S.5
Caputo, A.6
Goletti, D.7
Borsetti, A.8
Pace, M.9
Fanales-Belasio, E.10
Ridolfi, B.11
Negri, D.R.12
Sernicola, L.13
Belli, R.14
Corrias, F.15
Macchia, I.16
Leone, P.17
Michelini, Z.18
ten Haaft, P.19
Butto, S.20
Verani, P.21
Ensoli, B.22
more..
-
16
-
-
0032944291
-
Immunostimulatory CpG motifs trigger a T helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins
-
Deml, L., Schirmbeck, R., Reimann, J., Wolf, H. and Wagner, R. 1999. Immunostimulatory CpG motifs trigger a T helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins. Clin. Chem. Lab. Med. 37:199.
-
(1999)
Clin. Chem. Lab. Med.
, vol.37
, pp. 199
-
-
Deml, L.1
Schirmbeck, R.2
Reimann, J.3
Wolf, H.4
Wagner, R.5
-
17
-
-
0035147582
-
Human immunodeficiency virus (HIV)-specific immune responses are generated with the simultaneous vaccination of a gp120-depleted, whole- killed HIV-1 immunogen with cytosine-phosphorothioate-guanine dinucleotide immunostimulatory sequences of DNA
-
Moss, R. B., Diveley, J., Jensen, F. C., Gouveia, E. and Carlo, D. J. 2001. Human immunodeficiency virus (HIV)-specific immune responses are generated with the simultaneous vaccination of a gp120-depleted, whole- killed HIV-1 immunogen with cytosine-phosphorothioate-guanine dinucleotide immunostimulatory sequences of DNA. J. Hum. Virol. 4:39.
-
(2001)
J. Hum. Virol.
, vol.4
, pp. 39
-
-
Moss, R.B.1
Diveley, J.2
Jensen, F.C.3
Gouveia, E.4
Carlo, D.J.5
-
19
-
-
0032534602
-
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
-
Broide, D., Schwarze, J., Tighe, H., Gifford, T., Nguyen, M. D., Malek, S., Van Uden, J., Martin-Orozco, E., Gelfand, E. W. and Raz, E. 1998. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 161:7054.
-
(1998)
J. Immunol.
, vol.161
, pp. 7054
-
-
Broide, D.1
Schwarze, J.2
Tighe, H.3
Gifford, T.4
Nguyen, M.D.5
Malek, S.6
Van Uden, J.7
Martin-Orozco, E.8
Gelfand, E.W.9
Raz, E.10
-
20
-
-
0033563211
-
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
-
Sur, S., Wild, J. S., Choudhury, B. K., Sur, N., Alam, R. and Klinman, D. M. 1999. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J. Immunol. 162:6284.
-
(1999)
J. Immunol.
, vol.162
, pp. 6284
-
-
Sur, S.1
Wild, J.S.2
Choudhury, B.K.3
Sur, N.4
Alam, R.5
Klinman, D.M.6
-
21
-
-
0032521274
-
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
-
Kline, J. N., Waldschmidt, T. J., Businga, T. R., Lemish, J. E., Weinstock, J. V., Thorne, P. S. and Krieg, A. M. 1998. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J. Immunol. 160:2555.
-
(1998)
J. Immunol.
, vol.160
, pp. 2555
-
-
Kline, J.N.1
Waldschmidt, T.J.2
Businga, T.R.3
Lemish, J.E.4
Weinstock, J.V.5
Thorne, P.S.6
Krieg, A.M.7
-
23
-
-
0030955249
-
Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization
-
Weiner, G. J., Liu, H. M., Wooldridge, J. E., Dahle, C. E. and Krieg, A. M. 1997. Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. Proc. Natl Acad. Sci. USA 94:10833.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10833
-
-
Weiner, G.J.1
Liu, H.M.2
Wooldridge, J.E.3
Dahle, C.E.4
Krieg, A.M.5
-
24
-
-
0032533269
-
Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor
-
Liu, H. M., Newbrough, S. E., Bhatia, S. K., Dahle, C. E., Krieg, A. M. and Weiner, G. J. 1998. Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor. Blood 92:3730.
-
(1998)
Blood
, vol.92
, pp. 3730
-
-
Liu, H.M.1
Newbrough, S.E.2
Bhatia, S.K.3
Dahle, C.E.4
Krieg, A.M.5
Weiner, G.J.6
-
25
-
-
0034235701
-
Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity
-
Davila, E. and Celis, E. 2000. Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity. J. Immunol. 165:539.
-
(2000)
J. Immunol.
, vol.165
, pp. 539
-
-
Davila, E.1
Celis, E.2
-
27
-
-
0034087729
-
Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs
-
Carpentier, A. F., Xie, J., Mokhtari, K. and Delattre, J. Y. 2000. Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs. Clin. Cancer Res. 6:2469.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2469
-
-
Carpentier, A.F.1
Xie, J.2
Mokhtari, K.3
Delattre, J.Y.4
-
28
-
-
0033230505
-
Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice
-
Carpentier, A. F., Chen, L., Maltonti, F. and Delattre, J. Y. 1999. Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice. Cancer Res. 59:5429.
-
(1999)
Cancer Res.
, vol.59
, pp. 5429
-
-
Carpentier, A.F.1
Chen, L.2
Maltonti, F.3
Delattre, J.Y.4
-
29
-
-
18344398322
-
Cationic lipid:Bacterial DNA complexes elicit adaptive cellular immunity in murine intraperitoneal tumor models
-
Lanuti, M., Rudginsky, S., Force, S. D., Lambright, E. S., Siders, W. M., Chang, M. Y., Amin, K. M., Kaiser, L. R., Scheule, R. K. and Albelda, S. M. 2000. Cationic lipid:bacterial DNA complexes elicit adaptive cellular immunity in murine intraperitoneal tumor models. Cancer Res. 60:2955.
-
(2000)
Cancer Res.
, vol.60
, pp. 2955
-
-
Lanuti, M.1
Rudginsky, S.2
Force, S.D.3
Lambright, E.S.4
Siders, W.M.5
Chang, M.Y.6
Amin, K.M.7
Kaiser, L.R.8
Scheule, R.K.9
Albelda, S.M.10
-
30
-
-
0030900680
-
Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma
-
Wooldridge, J. E., Ballas, Z., Krieg, A. M. and Weiner, G. J. 1997. Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma. Blood 89:2994.
-
(1997)
Blood
, vol.89
, pp. 2994
-
-
Wooldridge, J.E.1
Ballas, Z.2
Krieg, A.M.3
Weiner, G.J.4
-
31
-
-
0034018567
-
Immunostimulatory CpG-oligonucleotides induce functional high affinity IL-2 receptors on B-CLI cells: Costimulation with IL-2 results in a highly immunogenic phenotype
-
Decker, T., Schneller, F., Kronschnabl, M., Dechow, T., Lipford, G. B., Wagner, H. and Peschel, C. 2000. Immunostimulatory CpG-oligonucleotides induce functional high affinity IL-2 receptors on B-CLI cells: costimulation with IL-2 results in a highly immunogenic phenotype. Exp. Hematol. 28:558.
-
(2000)
Exp. Hematol.
, vol.28
, pp. 558
-
-
Decker, T.1
Schneller, F.2
Kronschnabl, M.3
Dechow, T.4
Lipford, G.B.5
Wagner, H.6
Peschel, C.7
-
32
-
-
0034141541
-
Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells
-
Decker, T., Schneller, F., Sparwasser, T., Tretter, T., Lipford, G. B., Wagner, H. and Peschel, C. 2000. Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells. Blood 95:999.
-
(2000)
Blood
, vol.95
, pp. 999
-
-
Decker, T.1
Schneller, F.2
Sparwasser, T.3
Tretter, T.4
Lipford, G.B.5
Wagner, H.6
Peschel, C.7
-
33
-
-
0035155134
-
CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens
-
Jahrsdorfer, B., Hartmann, G., Racila, E., Jackson, W., Muhlenhoff, L., Meinhardt, G., Endres, S., Link, B. K., Krieg, A. M. and Weiner, G. J. 2001. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. J. Leukoc. Biol. 69:81.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 81
-
-
Jahrsdorfer, B.1
Hartmann, G.2
Racila, E.3
Jackson, W.4
Muhlenhoff, L.5
Meinhardt, G.6
Endres, S.7
Link, B.K.8
Krieg, A.M.9
Weiner, G.J.10
-
34
-
-
0033281621
-
A possible cause of joint destruction in septic arthritis
-
Krieg, A. M. 1999. A possible cause of joint destruction in septic arthritis. Arthritis Res. 1:3.
-
(1999)
Arthritis Res.
, vol.1
, pp. 3
-
-
Krieg, A.M.1
-
35
-
-
0033038486
-
Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis
-
Deng, G. M., Nilsson, I. M., Verdrengh, M., Collins, L. V. and Tarkowski, A. 1999. Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis. Nat. Med. 5:702.
-
(1999)
Nat. Med.
, vol.5
, pp. 702
-
-
Deng, G.M.1
Nilsson, I.M.2
Verdrengh, M.3
Collins, L.V.4
Tarkowski, A.5
-
36
-
-
0033758480
-
Unmethylated oligo-DNA containing CpG motifs aggravates collagen- induced arthritis in mice
-
Miyata, M., Kobayashi, H., Sasajima, T., Sato, Y. and Kasukawa, R. 2000. Unmethylated oligo-DNA containing CpG motifs aggravates collagen- induced arthritis in mice. Arthritis Rheum. 43:2578.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2578
-
-
Miyata, M.1
Kobayashi, H.2
Sasajima, T.3
Sato, Y.4
Kasukawa, R.5
-
37
-
-
0029934754
-
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
-
Cowdery, J. S., Chace, J. H., Yi, A. K. and Krieg, A. M. 1996. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J. Immunol. 156:4570.
-
(1996)
J. Immunol.
, vol.156
, pp. 4570
-
-
Cowdery, J.S.1
Chace, J.H.2
Yi, A.K.3
Krieg, A.M.4
-
38
-
-
0035112910
-
Enhancing vaccines with immune stimulatory CpG DNA
-
Krieg, A. M. and Davis, H. L. 2001. Enhancing vaccines with immune stimulatory CpG DNA. Curr. Opin. Mol. Ther. 3:15.
-
(2001)
Curr. Opin. Mol. Ther.
, vol.3
, pp. 15
-
-
Krieg, A.M.1
Davis, H.L.2
-
39
-
-
0031569601
-
Contribution of CpG motifs to the immunogenicity of DNA vaccines
-
Klinman, D. M., Yamshchikov, G. and Ishigatsubo, Y. 1997. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 158:3635.
-
(1997)
J. Immunol.
, vol.158
, pp. 3635
-
-
Klinman, D.M.1
Yamshchikov, G.2
Ishigatsubo, Y.3
-
40
-
-
8944253295
-
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization
-
Sato, Y., Roman, M., Tighe, H., Lee, D., Corr, M., Nguyen, M. D., Silverman, G. J., Lotz, M., Carson, D. A. and Raz, E. 1996. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273:352.
-
(1996)
Science
, vol.273
, pp. 352
-
-
Sato, Y.1
Roman, M.2
Tighe, H.3
Lee, D.4
Corr, M.5
Nguyen, M.D.6
Silverman, G.J.7
Lotz, M.8
Carson, D.A.9
Raz, E.10
-
41
-
-
0033762213
-
Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs
-
Zhao, H., Cheng, S. H. and Yew, N. S. 2000. Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs. Antisense Nucleic Acid Drug Dev. 10:381.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 381
-
-
Zhao, H.1
Cheng, S.H.2
Yew, N.S.3
-
42
-
-
0034149827
-
Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
-
Yew, N. S., Zhao, H., Wu, I. H., Song, A., Tousignant, J. D., Przybylska, M. and Cheng, S. H. 2000. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol. Ther. 1:255.
-
(2000)
Mol. Ther.
, vol.1
, pp. 255
-
-
Yew, N.S.1
Zhao, H.2
Wu, I.H.3
Song, A.4
Tousignant, J.D.5
Przybylska, M.6
Cheng, S.H.7
-
43
-
-
0033199598
-
The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo
-
Tan, Y., Li, S., Pitt, B. R. and Huang, L. 1999. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum. Gene Ther. 10:2153.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2153
-
-
Tan, Y.1
Li, S.2
Pitt, B.R.3
Huang, L.4
-
44
-
-
0033749220
-
The role of immunostimulatory CpG-DNA in septic shock
-
Wagner, H., Lipford, G. B. and Hacker, H. 2000. The role of immunostimulatory CpG-DNA in septic shock. Semin. Immunopathol. 22:167.
-
(2000)
Semin. Immunopathol.
, vol.22
, pp. 167
-
-
Wagner, H.1
Lipford, G.B.2
Hacker, H.3
-
45
-
-
0030897625
-
Bacterial DNA causes septic shock
-
Sparwasser, T., Miethke, T., Lipford, G., Borschert, K., Hacker, H., Heeg, K. and Wagner, H. 1997. Bacterial DNA causes septic shock. Nature 386:336.
-
(1997)
Nature
, vol.386
, pp. 336
-
-
Sparwasser, T.1
Miethke, T.2
Lipford, G.3
Borschert, K.4
Hacker, H.5
Heeg, K.6
Wagner, H.7
-
46
-
-
0032844828
-
Multivalent cross-linking of membrane Ig sensitizes murine B cells to a broader spectrum of CpG-containing oligodeoxynucleotide motifs, including their methylated counterparts, for stimulation of proliferation and Ig secretion
-
Goeckeritz, B. E., Flora, M., Witherspoon, K., Vos, Q., Lees, A., Dennis, G. J., Pisetsky, D. S., Klinman, D. M., Snapper, C. M. and Mond, J. J. 1999. Multivalent cross-linking of membrane Ig sensitizes murine B cells to a broader spectrum of CpG-containing oligodeoxynucleotide motifs, including their methylated counterparts, for stimulation of proliferation and Ig secretion. Int. Immunol. 11:1693.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1693
-
-
Goeckeritz, B.E.1
Flora, M.2
Witherspoon, K.3
Vos, Q.4
Lees, A.5
Dennis, G.J.6
Pisetsky, D.S.7
Klinman, D.M.8
Snapper, C.M.9
Mond, J.J.10
-
47
-
-
0023729241
-
Altered immunoglobulin expression and functional silencing of self- reactive B lymphocytes in transgenic mice
-
Goodnow, C. C., Crosbie, J., Adelstein, S., Lavoie, T. B., Smith-Gill, S. J., Brink, R. A., Pritchard-Briscoe, H., Wotherspoon, J. S., Loblay, R. H., Raphael, K., Trent, R. J. and Basten, A.. 1988. Altered immunoglobulin expression and functional silencing of self- reactive B lymphocytes in transgenic mice. Nature 334:676.
-
(1988)
Nature
, vol.334
, pp. 676
-
-
Goodnow, C.C.1
Crosbie, J.2
Adelstein, S.3
Lavoie, T.B.4
Smith-Gill, S.J.5
Brink, R.A.6
Pritchard-Briscoe, H.7
Wotherspoon, J.S.8
Loblay, R.H.9
Raphael, K.10
Trent, R.J.11
Basten, A.12
-
48
-
-
0022980048
-
Studies on the specificity of antibodies to ovalbumin in normal human serum: Technical considerations in the use of ELISA methods
-
Kilshaw, P. J., McEwan, F. J., Baker, K. C. and Cant, A. J. 1986. Studies on the specificity of antibodies to ovalbumin in normal human serum: technical considerations in the use of ELISA methods. Clin. Exp. Immunol. 66:481.
-
(1986)
Clin. Exp. Immunol.
, vol.66
, pp. 481
-
-
Kilshaw, P.J.1
McEwan, F.J.2
Baker, K.C.3
Cant, A.J.4
-
50
-
-
0031915373
-
CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel
-
Yi, A. K. and Krieg, A. M. 1998. CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel. J. Immunol. 160:1240.
-
(1998)
J. Immunol.
, vol.160
, pp. 1240
-
-
Yi, A.K.1
Krieg, A.M.2
-
52
-
-
0034254713
-
The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides
-
Liang, H., Reich, C. F., Pisetsky, D. S. and Lipsky, P. E. 2000. The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides. J. Immunol. 165:1438.
-
(2000)
J. Immunol.
, vol.165
, pp. 1438
-
-
Liang, H.1
Reich, C.F.2
Pisetsky, D.S.3
Lipsky, P.E.4
-
53
-
-
0030806663
-
Characterization and modulation of immune stimulation by modified oligonucleotides
-
Boggs, R. T., McGraw, K., Condon, T., Flournoy, S., Villiet, P., Bennett, C. F. and Monia, B. P. 1997. Characterization and modulation of immune stimulation by modified oligonucleotides. Antisense Nucleic Acid Drug Dev. 7:461.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 461
-
-
Boggs, R.T.1
McGraw, K.2
Condon, T.3
Flournoy, S.4
Villiet, P.5
Bennett, C.F.6
Monia, B.P.7
-
54
-
-
0034668209
-
Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants
-
McCluskie, M. J. and Davis, H. L. 2000. Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants. Vaccine 19:413.
-
(2000)
Vaccine
, vol.19
, pp. 413
-
-
McCluskie, M.J.1
Davis, H.L.2
-
56
-
-
0035451081
-
Genomic DNA released by dying cells induces the maturation of APCs
-
Ishii, K. J., Suzuki, K., Coban, C., Takeshita, F., Itoh, Y., Matoba, H., Kohn, L. D. and Klinman, D. M. 2001. Genomic DNA released by dying cells induces the maturation of APCs. J. Immunol. 167:2602.
-
(2001)
J. Immunol.
, vol.167
, pp. 2602
-
-
Ishii, K.J.1
Suzuki, K.2
Coban, C.3
Takeshita, F.4
Itoh, Y.5
Matoba, H.6
Kohn, L.D.7
Klinman, D.M.8
-
57
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K. and Akira, S. 2000. A Toll-like receptor recognizes bacterial DNA. Nature 408:740.
-
(2000)
Nature
, vol.408
, pp. 740
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
58
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer, S., Kirschning, C. J., Hacker, H., Redecke, V., Hausmann, S., Akira, S., Wagner, H. and Lipford, G. B. 2001. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc. Natl Acad. Sci. USA 98:9237.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9237
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
Wagner, H.7
Lipford, G.B.8
-
59
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter, E. A., Rifkin, I. R., Hohlbaum, A. M., Beaudette, B. C., Shlomchilk, M. J. and Marshak-Rothstein, A. 2002. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416:603.
-
(2002)
Nature
, vol.416
, pp. 603
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchilk, M.J.5
Marshak-Rothstein, A.6
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