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Volumn 106, Issue 1, 2009, Pages 63-72

Cyclin D1 downregulation Is important for permanent cell cycle exit and initiation of differentiation induced by anchorage-deprivation in human keratinocytes

Author keywords

Anchorage deprivation; Cyclin D1; Differentiation; Keratinocytes; Permanent cell cycle Exit

Indexed keywords

CYCLIN D1; INVOLUCRIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

EID: 58649121993     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21978     Document Type: Article
Times cited : (28)

References (53)
  • 2
    • 33746524819 scopus 로고    scopus 로고
    • Gain of 11q/cyclin D1 overexpression is an essential early step in skin cancer development and causes abnormal tissue organization and differentiation
    • Burnworth B, Popp S, Stark HJ, Steinkraus V, Bröcker EB, Hartschuh W, Birek C, Boukamp P. 2006. Gain of 11q/cyclin D1 overexpression is an essential early step in skin cancer development and causes abnormal tissue organization and differentiation. Oncogene 25:4399-4412.
    • (2006) Oncogene , vol.25 , pp. 4399-4412
    • Burnworth, B.1    Popp, S.2    Stark, H.J.3    Steinkraus, V.4    Bröcker, E.B.5    Hartschuh, W.6    Birek, C.7    Boukamp, P.8
  • 3
    • 0031019197 scopus 로고    scopus 로고
    • Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation
    • Connell-Crowley L, Harper JW, Goodrich DW. 1997. Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. Mol Biol Cell 8:287-301.
    • (1997) Mol Biol Cell , vol.8 , pp. 287-301
    • Connell-Crowley, L.1    Harper, J.W.2    Goodrich, D.W.3
  • 4
    • 33750043466 scopus 로고    scopus 로고
    • p21WAF1/Cip1 suppresses keratinocyte differentiation independently of the cell cycle through transcriptional up-regulation of the IGF-I gene
    • Devgan V, Nguyen BC, Oh H, Dotto GP. 2006. p21WAF1/Cip1 suppresses keratinocyte differentiation independently of the cell cycle through transcriptional up-regulation of the IGF-I gene. J Biol Chem 281:30463-30470.
    • (2006) J Biol Chem , vol.281 , pp. 30463-30470
    • Devgan, V.1    Nguyen, B.C.2    Oh, H.3    Dotto, G.P.4
  • 5
    • 0032523239 scopus 로고    scopus 로고
    • Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control
    • Di Cunto F, Topley G, Calautti E, Hsiao J, Ong L, Seth PK, Dotto GP. 1998. Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control. Science 280:1069-1072.
    • (1998) Science , vol.280 , pp. 1069-1072
    • Di Cunto, F.1    Topley, G.2    Calautti, E.3    Hsiao, J.4    Ong, L.5    Seth, P.K.6    Dotto, G.P.7
  • 6
    • 0027361671 scopus 로고
    • Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations
    • Drozdoff V, Pledger WJ. 1993. Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations. J Cell Biol 123:909-919.
    • (1993) J Cell Biol , vol.123 , pp. 909-919
    • Drozdoff, V.1    Pledger, W.J.2
  • 7
    • 0033711708 scopus 로고    scopus 로고
    • Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle
    • Ekholm SV, Reed SI. 2000. Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle. Curr Opin Cell Biol 12:676-684.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 676-684
    • Ekholm, S.V.1    Reed, S.I.2
  • 8
    • 1642603438 scopus 로고    scopus 로고
    • The activities of cyclin D1 that drive tumorigenesis
    • Ewen ME, Lamb J. 2004. The activities of cyclin D1 that drive tumorigenesis. Trends Mol Med 10:158-162.
    • (2004) Trends Mol Med , vol.10 , pp. 158-162
    • Ewen, M.E.1    Lamb, J.2
  • 9
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM. 1993. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73:487-497.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 10
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. 2004. Minireview: Cyclin D1: Normal and abnormal functions. Endocrinology 145:5439-5447.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 11
    • 0025679060 scopus 로고
    • Epidermal differentiation: The bare essentials
    • Fuchs E. 1990. Epidermal differentiation: The bare essentials. J Cell Biol 111:2807-2814.
    • (1990) J Cell Biol , vol.111 , pp. 2807-2814
    • Fuchs, E.1
  • 12
    • 0017756282 scopus 로고
    • Terminal differentiation of cultured human epidermal cells
    • Green H. 1977. Terminal differentiation of cultured human epidermal cells. Cell 11:405-416.
    • (1977) Cell , vol.11 , pp. 405-416
    • Green, H.1
  • 13
    • 32244441908 scopus 로고    scopus 로고
    • From cell cycle to differentiation: An expanding role for cdk6
    • Grossel MJ, Hinds PW. 2006. From cell cycle to differentiation: An expanding role for cdk6. Cell Cycle 5:266-270.
    • (2006) Cell Cycle , vol.5 , pp. 266-270
    • Grossel, M.J.1    Hinds, P.W.2
  • 14
    • 0031750613 scopus 로고    scopus 로고
    • Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation
    • Harvat BL, Wang A, Seth P, Jetten AM. 1998. Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation. J Cell Sci 111:1185-1196.
    • (1998) J Cell Sci , vol.111 , pp. 1185-1196
    • Harvat, B.L.1    Wang, A.2    Seth, P.3    Jetten, A.M.4
  • 15
    • 0030614671 scopus 로고    scopus 로고
    • The role ofp27kip1 in the in vitro differentiation of murine keratinocytes
    • Hauser PJ, Agrawal D, Flanagan M, Pledger WJ. 1997. The role ofp27kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ 8:203-211.
    • (1997) Cell Growth Differ , vol.8 , pp. 203-211
    • Hauser, P.J.1    Agrawal, D.2    Flanagan, M.3    Pledger, W.J.4
  • 16
    • 1342301636 scopus 로고    scopus 로고
    • Efficient down-regulation of cyclin A-associated activity and expression in suspended primary keratinocytes requires p21(Cip1)
    • Hauser P, Ma L, Agrawal D, Haura E, Cress WD, Pledger WJ. 2004. Efficient down-regulation of cyclin A-associated activity and expression in suspended primary keratinocytes requires p21(Cip1). Mol Cancer Res 2:96-104.
    • (2004) Mol Cancer Res , vol.2 , pp. 96-104
    • Hauser, P.1    Ma, L.2    Agrawal, D.3    Haura, E.4    Cress, W.D.5    Pledger, W.J.6
  • 17
    • 0034768547 scopus 로고    scopus 로고
    • Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway
    • Jost M, Huggett TM, Kari C, Rodeck U. 2001. Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Mol Biol Cell 12:1519-1527.
    • (2001) Mol Biol Cell , vol.12 , pp. 1519-1527
    • Jost, M.1    Huggett, T.M.2    Kari, C.3    Rodeck, U.4
  • 19
    • 0033563702 scopus 로고    scopus 로고
    • NA22598, a novel antitumor compound, reduces cyclin D1 levels, arrests cell cycle at G1 phase, and inhibits anchorage-independent growth of human tumor cells
    • Kawada M, Kuwahara A, Nishikiori T, Mizuno S, Uehara Y. 1999. NA22598, a novel antitumor compound, reduces cyclin D1 levels, arrests cell cycle at G1 phase, and inhibits anchorage-independent growth of human tumor cells. Exp Cell Res 249:240-247.
    • (1999) Exp Cell Res , vol.249 , pp. 240-247
    • Kawada, M.1    Kuwahara, A.2    Nishikiori, T.3    Mizuno, S.4    Uehara, Y.5
  • 21
    • 0026318222 scopus 로고
    • Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally
    • Lechner MS, Laimins LA. 1991. Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally. Virology 185:563-571.
    • (1991) Virology , vol.185 , pp. 563-571
    • Lechner, M.S.1    Laimins, L.A.2
  • 23
    • 0038795323 scopus 로고    scopus 로고
    • Cyclin D1 is necessary but not sufficient for anchorage-independent growth of rat mammary tumor cells and is associated with resistance of the Copenhagen rat to mammary carcinogenesis
    • Li YJ, Song R, Korkola JE, Archer MC, Ben-David Y. 2003. Cyclin D1 is necessary but not sufficient for anchorage-independent growth of rat mammary tumor cells and is associated with resistance of the Copenhagen rat to mammary carcinogenesis. Oncogene 22:3452-3462.
    • (2003) Oncogene , vol.22 , pp. 3452-3462
    • Li, Y.J.1    Song, R.2    Korkola, J.E.3    Archer, M.C.4    Ben-David, Y.5
  • 24
    • 0033590071 scopus 로고    scopus 로고
    • The retinoblastoma gene family in differentiation and development
    • Lipinski MM, Jacks T. 1999. The retinoblastoma gene family in differentiation and development. Oncogene 18:7873-7882.
    • (1999) Oncogene , vol.18 , pp. 7873-7882
    • Lipinski, M.M.1    Jacks, T.2
  • 25
    • 0033552953 scopus 로고    scopus 로고
    • Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation
    • Martinez LA, Chen Y, Fischer SM, Conti CJ. 1999. Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation. Oncogene 18:397-406.
    • (1999) Oncogene , vol.18 , pp. 397-406
    • Martinez, L.A.1    Chen, Y.2    Fischer, S.M.3    Conti, C.J.4
  • 26
    • 0025819962 scopus 로고
    • Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
    • Matsushime H, Roussel MF, Ashmun RA, Sherr CJ. 1991. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65:701-713.
    • (1991) Cell , vol.65 , pp. 701-713
    • Matsushime, H.1    Roussel, M.F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 27
    • 0038375546 scopus 로고    scopus 로고
    • CDK6 blocks differentiation: Coupling cell proliferation to the block to differentiation in leukemic cells
    • Matushansky I, Radparvar F, Skoultchi AI. 2003. CDK6 blocks differentiation: Coupling cell proliferation to the block to differentiation in leukemic cells. Oncogene 22:4143-4149.
    • (2003) Oncogene , vol.22 , pp. 4143-4149
    • Matushansky, I.1    Radparvar, F.2    Skoultchi, A.I.3
  • 28
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • Meloche S, Pouyssegur J. 2007. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 26:3227-3239.
    • (2007) Oncogene , vol.26 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 29
    • 0029658030 scopus 로고    scopus 로고
    • The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
    • Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP. 1996. The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev 10:3065-3075.
    • (1996) Genes Dev , vol.10 , pp. 3065-3075
    • Missero, C.1    Di Cunto, F.2    Kiyokawa, H.3    Koff, A.4    Dotto, G.P.5
  • 31
    • 0036430684 scopus 로고    scopus 로고
    • Cell shape change precedes staurosporine-induced stabilization and accumulation of p27kip1
    • Nishi K, Schnier JB, Bradbury ME. 2002. Cell shape change precedes staurosporine-induced stabilization and accumulation of p27kip1. Exp Cell Res 280:233-243.
    • (2002) Exp Cell Res , vol.280 , pp. 233-243
    • Nishi, K.1    Schnier, J.B.2    Bradbury, M.E.3
  • 32
  • 33
    • 0032572755 scopus 로고    scopus 로고
    • Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiation
    • Paramio JM, Laín S, Segrelles C, Lane EB, Jorcano JL. 1998. Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiation. Oncogene 17:949-957.
    • (1998) Oncogene , vol.17 , pp. 949-957
    • Paramio, J.M.1    Laín, S.2    Segrelles, C.3    Lane, E.B.4    Jorcano, J.L.5
  • 34
    • 0030740215 scopus 로고    scopus 로고
    • Ectopic expression of cyclin D1 but not cyclin E induces anchorage-independent cell cycle progression
    • Resnitzky D. 1997. Ectopic expression of cyclin D1 but not cyclin E induces anchorage-independent cell cycle progression. Mol Cell Biol 17:5640-5647.
    • (1997) Mol Cell Biol , vol.17 , pp. 5640-5647
    • Resnitzky, D.1
  • 35
    • 0019124443 scopus 로고
    • Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes
    • Rheinwald JG, Beckett MA. 1980. Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell 22:629-632.
    • (1980) Cell , vol.22 , pp. 629-632
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 36
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas
    • Rheinwald JG, Beckett MA. 1981. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res 41:1657-1663.
    • (1981) Cancer Res , vol.41 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 37
    • 0016728261 scopus 로고
    • Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma
    • Rheinwald JG, Green H. 1975. Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma. Cell 6:317-330.
    • (1975) Cell , vol.6 , pp. 317-330
    • Rheinwald, J.G.1    Green, H.2
  • 38
    • 0027399720 scopus 로고
    • Elevation of cell cycle control proteins during spontaneous immortalization of human keratinocytes
    • Rice RH, Steinmann KE, deGraffenried LA, Qin Q, Taylor N, Schlegel R. 1993. Elevation of cell cycle control proteins during spontaneous immortalization of human keratinocytes. Mol Biol Cell 4:185-194.
    • (1993) Mol Biol Cell , vol.4 , pp. 185-194
    • Rice, R.H.1    Steinmann, K.E.2    deGraffenried, L.A.3    Qin, Q.4    Taylor, N.5    Schlegel, R.6
  • 39
    • 0033848878 scopus 로고    scopus 로고
    • Integrating the MAP kinase signal into the G1 phase cell cycle machinery
    • Roovers K, Assoian RK. 2000. Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays 22:818-826.
    • (2000) Bioessays , vol.22 , pp. 818-826
    • Roovers, K.1    Assoian, R.K.2
  • 40
    • 0032589393 scopus 로고    scopus 로고
    • Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells
    • Roovers K, Davey G, Zhu X, Bottazzi ME, Assoian RK. 1999. Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells. Mol Biol Cell 10: 3197-3204.
    • (1999) Mol Biol Cell , vol.10 , pp. 3197-3204
    • Roovers, K.1    Davey, G.2    Zhu, X.3    Bottazzi, M.E.4    Assoian, R.K.5
  • 41
    • 0032505579 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium
    • Ruesch MN, Laimins LA. 1998. Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium. Virology 250:19-29.
    • (1998) Virology , vol.250 , pp. 19-29
    • Ruesch, M.N.1    Laimins, L.A.2
  • 42
    • 0028073511 scopus 로고
    • The kinase inhibitor staurosporine induces G1 arrest at two points: Effect on retinoblastoma protein phosphorylation and cyclin-dependent kinase 2 in normal and transformed cells
    • Schnier JB, Gadbois DM, Nishi K, Bradbury EM. 1994. The kinase inhibitor staurosporine induces G1 arrest at two points: Effect on retinoblastoma protein phosphorylation and cyclin-dependent kinase 2 in normal and transformed cells. Cancer Res 54:5959-5963.
    • (1994) Cancer Res , vol.54 , pp. 5959-5963
    • Schnier, J.B.1    Gadbois, D.M.2    Nishi, K.3    Bradbury, E.M.4
  • 43
    • 0024259984 scopus 로고
    • Human squamous carcinoma cells express complex defects in the control of proliferation and differentiation
    • Scott RE, Wilke MS, Wille JJ, Jr., Pittelkow MR, Hsu BM, Kasperbauer JL. 1988. Human squamous carcinoma cells express complex defects in the control of proliferation and differentiation. Am J Pathol 133:374-380.
    • (1988) Am J Pathol , vol.133 , pp. 374-380
    • Scott, R.E.1    Wilke, M.S.2    Wille Jr., J.J.3    Pittelkow, M.R.4    Hsu, B.M.5    Kasperbauer, J.L.6
  • 44
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. 1996. Cancer cell cycles. Science 274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 45
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. 1999. CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev 13:1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 46
    • 0031876217 scopus 로고    scopus 로고
    • Regulation of differentiation by HBP1, a target of the retinoblastoma protein
    • Shih HH, Tevosian SG, Yee AS. 1998. Regulation of differentiation by HBP1, a target of the retinoblastoma protein. Mol Cell Biol 18:4732-4743.
    • (1998) Mol Cell Biol , vol.18 , pp. 4732-4743
    • Shih, H.H.1    Tevosian, S.G.2    Yee, A.S.3
  • 47
    • 33748945325 scopus 로고    scopus 로고
    • Changes in motility, gene expression and actin dynamics: Cdk6-induced cytoskeletal changes associated with differentiation in mouse astrocytes
    • Slomiany P, Baker T, Elliott ER, Grossel MJ. 2006. Changes in motility, gene expression and actin dynamics: Cdk6-induced cytoskeletal changes associated with differentiation in mouse astrocytes. J Cell Biochem 99:635-646.
    • (2006) J Cell Biochem , vol.99 , pp. 635-646
    • Slomiany, P.1    Baker, T.2    Elliott, E.R.3    Grossel, M.J.4
  • 49
    • 0034682037 scopus 로고    scopus 로고
    • Cell-cycle inhibitors: Three families united by a common cause
    • Vidal A, Koff A. 2000. Cell-cycle inhibitors: Three families united by a common cause. Gene 247:1-15.
    • (2000) Gene , vol.247 , pp. 1-15
    • Vidal, A.1    Koff, A.2
  • 50
    • 0030883584 scopus 로고    scopus 로고
    • Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase
    • Weber JD, Raben DM, Phillips PJ, Baldassare JJ. 1997. Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase. Biochem J 326:61 - 68.
    • (1997) Biochem J , vol.326 , pp. 61-68
    • Weber, J.D.1    Raben, D.M.2    Phillips, P.J.3    Baldassare, J.J.4
  • 52
    • 0021855166 scopus 로고
    • Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
    • Zetterberg A, Larsson O. 1985. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc Natl Acad Sci USA 82:5365-5369.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5365-5369
    • Zetterberg, A.1    Larsson, O.2
  • 53
    • 0034629319 scopus 로고    scopus 로고
    • Induction of anchorage-independent growth by transforming growth factor-beta linked to anchorage-independent expression of cyclin D1
    • Zhu X, Scharf E, Assoian RK. 2000. Induction of anchorage-independent growth by transforming growth factor-beta linked to anchorage-independent expression of cyclin D1. J Biol Chem 275:6703-6706.
    • (2000) J Biol Chem , vol.275 , pp. 6703-6706
    • Zhu, X.1    Scharf, E.2    Assoian, R.K.3


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