-
1
-
-
15644381140
-
Amphistin, a new melanogenesis inhibitor, produced by an actinomycete
-
Arai, N., Shiomi, K., Takamatsu, S., Komiyama, K., Shinose, M., Takahashi, Y., Tanaka, Y., Iwai, Y., Liu, J. R., and Omura, S. (1997). Amphistin, a new melanogenesis inhibitor, produced by an actinomycete. J. Antibiot. (Tokyo) 50, 808-814.
-
(1997)
J. Antibiot. (Tokyo)
, vol.50
, pp. 808-814
-
-
Arai, N.1
Shiomi, K.2
Takamatsu, S.3
Komiyama, K.4
Shinose, M.5
Takahashi, Y.6
Tanaka, Y.7
Iwai, Y.8
Liu, J.R.9
Omura, S.10
-
2
-
-
0022491419
-
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase
-
Tamaoki, T., Nomoto, H., Takahashi, I., Kato, Y., Morimoto, M., and Tomita, F. (1986). Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Biochem. Biophys. Res. Commum. 135, 397-402.
-
(1986)
Biochem. Biophys. Res. Commum.
, vol.135
, pp. 397-402
-
-
Tamaoki, T.1
Nomoto, H.2
Takahashi, I.3
Kato, Y.4
Morimoto, M.5
Tomita, F.6
-
3
-
-
0026548701
-
Kinetic analysis of protein kinase C inhibition by staurosporine: Evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates
-
Ward, N. E., and O'Brian, C. A. (1992). Kinetic analysis of protein kinase C inhibition by staurosporine: Evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates. Mol. Pharmacol. 41, 387-392.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 387-392
-
-
Ward, N.E.1
O'Brian, C.A.2
-
4
-
-
0023258497
-
Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60
-
Nakano, H., Kobayashi, E., Takahashi, I., Tamaoki, T., Kuzuu, Y., and Iba, H. (1987). Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60. J. Antibiot. (Tokyo) 40, 706-708.
-
(1987)
J. Antibiot. (Tokyo)
, vol.40
, pp. 706-708
-
-
Nakano, H.1
Kobayashi, E.2
Takahashi, I.3
Tamaoki, T.4
Kuzuu, Y.5
Iba, H.6
-
6
-
-
0026650953
-
Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases
-
Gadbois, D. M., Hamaguchi, J. R., Swank, R. A., and Bradbury, E. M. (1992). Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases. Biochem. Biophys. Res. Commun. 184, 80-85.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.184
, pp. 80-85
-
-
Gadbois, D.M.1
Hamaguchi, J.R.2
Swank, R.A.3
Bradbury, E.M.4
-
7
-
-
0025871634
-
Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle
-
Crissman, H. A., Gadbois, D. M., Tobey, R. A., and Bradbury, E. M. (1991). Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle. Proc. Natl. Acad. Sci. USA 88, 7580-7584.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7580-7584
-
-
Crissman, H.A.1
Gadbois, D.M.2
Tobey, R.A.3
Bradbury, E.M.4
-
8
-
-
0026081048
-
Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, apotent inhibitor of protein kinases
-
Abe, K., Yoshida, M., Usui, T., Horinouchi, S., and Beppu, T. (1991). Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, apotent inhibitor of protein kinases. Exp. Cell Res. 192, 122-127.
-
(1991)
Exp. Cell Res.
, vol.192
, pp. 122-127
-
-
Abe, K.1
Yoshida, M.2
Usui, T.3
Horinouchi, S.4
Beppu, T.5
-
9
-
-
0026794211
-
Reversible G1 arrest of a human lung epithelial cell line by staurosporine
-
Lin, Y., Chrest, F. J., and Gabrielson, E. W. (1992). Reversible G1 arrest of a human lung epithelial cell line by staurosporine. J. Cell Physiol. 152, 646-653.
-
(1992)
J. Cell Physiol.
, vol.152
, pp. 646-653
-
-
Lin, Y.1
Chrest, F.J.2
Gabrielson, E.W.3
-
10
-
-
0028073511
-
The kinase inhibitor staurosporine induces G1 arrest at two points: Effect on retinoblastoma protein phosphorylation and cyclin-dependent kinase 2 in normal and transformed cells
-
Schnier, J. B., Gadbois, D. M., Nishi, K., and Bradbury, E. M. (1994). The kinase inhibitor staurosporine induces G1 arrest at two points: Effect on retinoblastoma protein phosphorylation and cyclin-dependent kinase 2 in normal and transformed cells. Cancer Res. 54, 5959-5963.
-
(1994)
Cancer Res.
, vol.54
, pp. 5959-5963
-
-
Schnier, J.B.1
Gadbois, D.M.2
Nishi, K.3
Bradbury, E.M.4
-
11
-
-
0029664906
-
G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637
-
Schnier, J. B., Nishi, K., Goodrich, D. W., and Bradbury, E. M. (1996). G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637. Proc. Natl. Acad. Sci. USA 93, 5941-5946.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5941-5946
-
-
Schnier, J.B.1
Nishi, K.2
Goodrich, D.W.3
Bradbury, E.M.4
-
12
-
-
0032531142
-
The accumulation of cyclin-dependent kinase inhibitor p27kip1 is a primary response to staurosporine and independent of G1 cell cycle arrest
-
Nishi, K., Schnier, J. B., and Bradbury, E. M. (1998). The accumulation of cyclin-dependent kinase inhibitor p27kip1 is a primary response to staurosporine and independent of G1 cell cycle arrest. Exp. Cell Res. 243, 222-231.
-
(1998)
Exp. Cell Res.
, vol.243
, pp. 222-231
-
-
Nishi, K.1
Schnier, J.B.2
Bradbury, E.M.3
-
13
-
-
0025335601
-
Staurosporine induces dissolution of microfilament bundles by a protein kinase C-independent pathway
-
Hedberg, K. K., Birrell, G. B., Habliston, D. L., and Griffith, O. H. (1990) Staurosporine induces dissolution of microfilament bundles by a protein kinase C-independent pathway. Exp. Cell Res. 188, 199-208.
-
(1990)
Exp. Cell Res.
, vol.188
, pp. 199-208
-
-
Hedberg, K.K.1
Birrell, G.B.2
Habliston, D.L.3
Griffith, O.H.4
-
14
-
-
0028108047
-
Decreased phosphorylation of four 20-kDa proteins precedes staurosporine-induced disruption of the actin/myosin cytoskeleton in rat astrocytes
-
Mobley, P. L., Hedberg, K., Bonin, L., Chen, B., and Griffith, O. H. (1994). Decreased phosphorylation of four 20-kDa proteins precedes staurosporine-induced disruption of the actin/myosin cytoskeleton in rat astrocytes. Exp. Cell Res. 214, 55-66.
-
(1994)
Exp. Cell Res.
, vol.214
, pp. 55-66
-
-
Mobley, P.L.1
Hedberg, K.2
Bonin, L.3
Chen, B.4
Griffith, O.H.5
-
15
-
-
0030956506
-
Mechanism of the morphological changes induced by staurosporine in rat osteoblasts
-
Yang, R., Fu, W., Wang, S., Liu, T., and Lin-Shiau, S. (1997). Mechanism of the morphological changes induced by staurosporine in rat osteoblasts. Calcif. Tissue Int. 61, 68-73.
-
(1997)
Calcif. Tissue Int.
, vol.61
, pp. 68-73
-
-
Yang, R.1
Fu, W.2
Wang, S.3
Liu, T.4
Lin-Shiau, S.5
-
16
-
-
0021210339
-
A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells
-
Schliwa, M., Nakamura, T., Porter, K. R., and Euteneuer, U. (1984). A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells. J. Cell Biol. 99, 1045-1059.
-
(1984)
J. Cell Biol.
, vol.99
, pp. 1045-1059
-
-
Schliwa, M.1
Nakamura, T.2
Porter, K.R.3
Euteneuer, U.4
-
17
-
-
0023674315
-
Tumor promoter induces reorganization of actin filaments and calspectin (fodrin or nonerythroid spectrin) in 3T3 cells
-
Sobue, K., Fujio, Y., and Kanda, K. (1988). Tumor promoter induces reorganization of actin filaments and calspectin (fodrin or nonerythroid spectrin) in 3T3 cells. Proc. Natl. Acad. Sci. USA 85, 482-486.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 482-486
-
-
Sobue, K.1
Fujio, Y.2
Kanda, K.3
-
18
-
-
0023631394
-
GC-7 cells are growth arrested by cytochalasin D at two different points in the cell cycle
-
Takasuka, T., Ishibashi, S., and Ide, T. (1987). GC-7 cells are growth arrested by cytochalasin D at two different points in the cell cycle. Exp. Cell Res. 173, 287-293.
-
(1987)
Exp. Cell Res.
, vol.173
, pp. 287-293
-
-
Takasuka, T.1
Ishibashi, S.2
Ide, T.3
-
19
-
-
0025287304
-
Actin gene expression in murine erythroleukemia cells treated with cytochalasin D
-
Sympson, C. J., and Geoghegan, T. E. (1990). Actin gene expression in murine erythroleukemia cells treated with cytochalasin D. Exp. Cell Res. 189, 28-32.
-
(1990)
Exp. Cell Res.
, vol.189
, pp. 28-32
-
-
Sympson, C.J.1
Geoghegan, T.E.2
-
20
-
-
0031739360
-
Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension
-
Huang, S., Chen, C. S., and Ingber, D. E. (1998). Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Mol. Biol. Cell 9, 3179-3193.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3179-3193
-
-
Huang, S.1
Chen, C.S.2
Ingber, D.E.3
-
21
-
-
0034714510
-
Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein
-
Reshetnikova, G., Barkan, R., Popov, B., Nikolsky, N., and Chang, L. S. (2000). Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein. Exp. Cell Res. 259, 35-53.
-
(2000)
Exp. Cell Res.
, vol.259
, pp. 35-53
-
-
Reshetnikova, G.1
Barkan, R.2
Popov, B.3
Nikolsky, N.4
Chang, L.S.5
-
22
-
-
0030027049
-
Dependence of cyclin E-CDK2 kinase activity on cell anchorage
-
Fang, F., Orend, G., Watanabe, N., Hunter, T., and Ruoslahti, E. (1996). Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science 271, 499-502.
-
(1996)
Science
, vol.271
, pp. 499-502
-
-
Fang, F.1
Orend, G.2
Watanabe, N.3
Hunter, T.4
Ruoslahti, E.5
-
23
-
-
0029876639
-
Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
-
Zhu, X., Ohtsubo, M., Bohmer, R. M., Roberts, J. M., and As-soian, R. K. (1996). Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol. 133, 391-403.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 391-403
-
-
Zhu, X.1
Ohtsubo, M.2
Bohmer, R.M.3
Roberts, J.M.4
Assoian, R.K.5
-
24
-
-
0029783294
-
Anchorage-dependent transcription of the cyclin A gene
-
Schulze, A., Zerfass-Thome, K., Berges, J., Middendorp, S., Jansen-Durr, P., and Henglein, B. (1996). Anchorage-dependent transcription of the cyclin A gene. Mol. Cell Biol. 16, 4632-4638.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4632-4638
-
-
Schulze, A.1
Zerfass-Thome, K.2
Berges, J.3
Middendorp, S.4
Jansen-Durr, P.5
Henglein, B.6
-
25
-
-
0029417840
-
p27KIP1, an inhibitor of cyclin-dependent kinases
-
Koff, A., and Polyak, K. (1995). p27KIP1, an inhibitor of cyclin-dependent kinases. Prog. Cell Cycle Res. 1, 141-147.
-
(1995)
Prog. Cell Cycle Res.
, vol.1
, pp. 141-147
-
-
Koff, A.1
Polyak, K.2
-
26
-
-
0034092911
-
Regulation of the cdk inhibitor p27 and its deregulation in cancer
-
Slingerland, J., and Pagano, M. (2000). Regulation of the cdk inhibitor p27 and its deregulation in cancer. J. Cell Physiol. 183, 10-17.
-
(2000)
J. Cell Physiol.
, vol.183
, pp. 10-17
-
-
Slingerland, J.1
Pagano, M.2
-
27
-
-
0030727466
-
Cell cycle regulation by the ubiquitin pathway
-
Pagano, M. (1997). Cell cycle regulation by the ubiquitin pathway. FASEB J. 11, 1067-1075.
-
(1997)
FASEB J.
, vol.11
, pp. 1067-1075
-
-
Pagano, M.1
-
28
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano, M., Tam, S. W., Theodoras, A. M., Beer-Romero, P., Del Sal, G., Chau, V., Yew, P. R., Draetta, G. F., and Rolfe, M. (1995). Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269, 682-685.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
29
-
-
0033553390
-
Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation andproteolytic processing
-
Shirane, M., Harumiya, Y., Ishida, N., Hirai, A., Miyamoto, C., Hatakeyama, S., Nakayama, K., and Kitagawa, M. (1999). Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation andproteolytic processing. J. Biol. Chem. 274, 13886-13893.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13886-13893
-
-
Shirane, M.1
Harumiya, Y.2
Ishida, N.3
Hirai, A.4
Miyamoto, C.5
Hatakeyama, S.6
Nakayama, K.7
Kitagawa, M.8
-
30
-
-
0030847760
-
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
-
Vlach, J., Hennecke, S., and Amati, B. (1997). Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J. 16, 5334-5344.
-
(1997)
EMBO J.
, vol.16
, pp. 5334-5344
-
-
Vlach, J.1
Hennecke, S.2
Amati, B.3
-
31
-
-
0030997297
-
Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation
-
Alessandrini, A., Chiaur, D. S., and Pagano, M. (1997) Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation. Leukemia 11, 342-345.
-
(1997)
Leukemia
, vol.11
, pp. 342-345
-
-
Alessandrini, A.1
Chiaur, D.S.2
Pagano, M.3
-
32
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff, R. J., Groudine, M., Gordon, M., Roberts, J. M., and Clurman, B. E. (1997). Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11, 1464-1478.
-
(1997)
Genes Dev.
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
33
-
-
0035901969
-
Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells
-
Frost, V., Al-Mehairi, S., and Sinclair, A. J. (2001). Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells. Oncogene 20, 2737-2748.
-
(2001)
Oncogene
, vol.20
, pp. 2737-2748
-
-
Frost, V.1
Al-Mehairi, S.2
Sinclair, A.J.3
-
34
-
-
0035921821
-
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 phase
-
Malek, N. P., Sundberg, H., McGrew, S., Nakayama, K., Kyriakides, T. R., Roberts, J. M., and Kyriakidis, T. R. (2001). A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 phase. Nature 413, 323-327.
-
(2001)
Nature
, vol.413
, pp. 323-327
-
-
Malek, N.P.1
Sundberg, H.2
McGrew, S.3
Nakayama, K.4
Kyriakides, T.R.5
Roberts, J.M.6
Kyriakidis, T.R.7
-
35
-
-
0019320646
-
Cytochalasins block actin filament elongation by binding to high affinity sites associated with F-actin
-
Flanagan, M. D., and Lin, S. (1980). Cytochalasins block actin filament elongation by binding to high affinity sites associated with F-actin. J. Biol. Chem. 255, 835-838.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 835-838
-
-
Flanagan, M.D.1
Lin, S.2
-
36
-
-
0024502467
-
Actin filament capping and cleaving activity of cytochalasins B, D, E, and H
-
Urbanik, E., and Ware, B. R. (1989). Actin filament capping and cleaving activity of cytochalasins B, D, E, and H. Arch. Biochem. Biophys. 269, 181-187.
-
(1989)
Arch. Biochem. Biophys.
, vol.269
, pp. 181-187
-
-
Urbanik, E.1
Ware, B.R.2
-
37
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka, M., and Burridge, K. (1996). Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133, 1403-1415.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
38
-
-
0031050451
-
Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression
-
Assoian, R. K., and Zhu, X. (1997). Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. Curr. Opin. Cell Biol. 9, 93-98.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 93-98
-
-
Assoian, R.K.1
Zhu, X.2
-
39
-
-
0032936195
-
Cytoplasmic elongation and rupture in megakaryoblastic leukemia cells via activation of adhesion and motility by staurosporine on fibronectin-bound substratum
-
Yamazaki, Y., Sanokawa, R., Fujita, Y., Zhou, D., Kawasaki, K., Tanaka, H., Komatsu, T., Nagasawa, T., and Oka, S. (1999). Cytoplasmic elongation and rupture in megakaryoblastic leukemia cells via activation of adhesion and motility by staurosporine on fibronectin-bound substratum. J. Cell Physiol. 179, 179-192.
-
(1999)
J. Cell Physiol.
, vol.179
, pp. 179-192
-
-
Yamazaki, Y.1
Sanokawa, R.2
Fujita, Y.3
Zhou, D.4
Kawasaki, K.5
Tanaka, H.6
Komatsu, T.7
Nagasawa, T.8
Oka, S.9
-
40
-
-
0030582716
-
Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors
-
Koyama, H., Raines, E. W., Bornfeldt, K. E., Roberts, J. M., and Ross, R. (1996). Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors. Cell 87, 1069-1078.
-
(1996)
Cell
, vol.87
, pp. 1069-1078
-
-
Koyama, H.1
Raines, E.W.2
Bornfeldt, K.E.3
Roberts, J.M.4
Ross, R.5
-
41
-
-
15644378138
-
Geranyl-geranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progressionfrom G1 to S phase in growth-stimulated rat FRTL-5 cells
-
Hirai, A., Nakamura, S., Noguchi, Y., Yasuda, T., Kitagawa, M., Tatsuno, I., Oeda, T., Tahara, K., Terano, T., Narumiya, S., Kohn, L. D., and Saito, Y. (1997). Geranyl-geranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progressionfrom G1 to S phase in growth-stimulated rat FRTL-5 cells. J. Biol. Chem. 272, 13-16.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13-16
-
-
Hirai, A.1
Nakamura, S.2
Noguchi, Y.3
Yasuda, T.4
Kitagawa, M.5
Tatsuno, I.6
Oeda, T.7
Tahara, K.8
Terano, T.9
Narumiya, S.10
Kohn, L.D.11
Saito, Y.12
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