Zinc chromate induces chromosome instability and DNA double strand breaks in human lung cells

Toxicology and Applied Pharmacology

Volumn 234, Issue 3, 2009, Pages 293-299

  Xie, Hong ^a   Holmes, Amie L ^a   Young, Jamie L ^a   Qin, Qin ^a   Joyce, Kellie ^a   Pelsue, Stephen C ^a   Peng, Cheng ^a   Wise, Sandra S ^a   Jeevarajan, Antony S ^b   Wallace, William T ^b   Hammond, Dianne ^b   Wise Sr , John Pierce ^a  

^a UNIVERSITY OF SOUTHERN MAINE   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Chromium; Chromosome instability; DNA double strand breaks; Zinc chromate

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHROMIUM DERIVATIVE; MRE11 PROTEIN; UNCLASSIFIED DRUG; ZINC CHROMATE;

ARTICLE; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CHROMOSOMAL INSTABILITY; CHROMOSOME DAMAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MOLECULAR MECHANICS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL SURVIVAL; CHROMATES; CHROMOSOMAL INSTABILITY; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HUMANS; LUNG; MUTAGENS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION; ZINC COMPOUNDS;

ANIMALIA;

EID: 58649106890     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.10.010     Document Type: Article

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