Lead chromate-induced chromosome damage requires extracellular dissolution to liberate chromium ions but does not require particle internalization or intracellular dissolution

Chemical Research in Toxicology

Volumn 17, Issue 10, 2004, Pages 1362-1367

  Xie, Hong ^a   Holmes, Amie L ^a   Wise, Sandra S ^a   Gordon, Nancy ^a   Wise Sr , John Pierce ^a  

^a UNIVERSITY OF SOUTHERN MAINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CARCINOGEN; CHROMIC ACID; CHROMIUM; CLASTOGEN; LEAD CHROMATE;

ARTICLE; CARCINOGENICITY; CELL LINE; CELL VACUOLE; CELLULAR DISTRIBUTION; CHROMOSOME DAMAGE; CLASTOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISSOLUTION; EPITHELIUM CELL; FIBROBLAST; GENOTOXICITY; HUMAN; HUMAN CELL; INTERNALIZATION; LUNG ALVEOLUS CELL; LYSOSOME; PARTICLE SIZE; PARTICULATE MATTER; PHYSICAL CHEMISTRY; SOLUBILITY; TARGET CELL; TRANSMISSION ELECTRON MICROSCOPY;

ASCORBIC ACID; CELL CYCLE; CELL LINE; CHROMATES; CHROMIUM; CHROMOSOME ABERRATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FIBROBLASTS; HUMANS; INTRACELLULAR FLUID; LEAD; LUNG; LYSOSOMES; MICROSCOPY, ELECTRON; MUTAGENS; PARTICLE SIZE;

EID: 6344240821     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0498509     Document Type: Article

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