Carcinogenic lead chromate induces DNA double-strand breaks in human lung cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 586, Issue 2, 2005, Pages 160-172

  Xie, Hong ^a   Wise, Sandra S ^a   Holmes, Amie L ^a   Xu, Bo ^b   Wakeman, Timothy P ^b   Pelsue, Stephen C ^a   Singh, Narendra P ^c   Wise Sr , John Pierce ^a  

^a UNIVERSITY OF SOUTHERN MAINE   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Washington   (United States)

Author keywords

ATM; DNA double strand breaks; Hexavalent chromium; Lead chromate; Smc1

Indexed keywords

ATM PROTEIN; CARCINOGEN; DOUBLE STRANDED DNA; H2 ANTIGEN; LEAD CHROMATE; SERINE;

ARTICLE; BRONCHUS; CARCINOGENIC ACTIVITY; CELL COUNT; CHEMICAL CARCINOGENESIS; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IONIZING RADIATION; LUNG ALVEOLUS CELL; LUNG CARCINOGENESIS; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

CELL CYCLE PROTEINS; CHROMATES; COMET ASSAY; DNA DAMAGE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; LEAD; LUNG; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SODIUM COMPOUNDS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

ATAXIA TELANGIECTASIA;

EID: 28644436221     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2005.06.002     Document Type: Article

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