Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2)

Toxicology and Applied Pharmacology

Volumn 234, Issue 3, 2009, Pages 281-292

  Qadri, Ishtiaq ^a   Hu, Ling Jia ^b   Iwahashi, Mieko ^b   Al Zuabi, Subhi ^b   Quattrochi, Linda C ^b   Simon, Francis R ^b  

^a NATIONAL UNIVERSITY OF SCIENCES AND TECHNOLOGY   (Pakistan)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Cellular detoxification; HNF1 and HNF4 role; Liver specific expression; MRP2 regulation

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE 2; GLUCOCORTICOID; HEPATOCYTE NUCLEAR FACTOR; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LUCIFERASE; MULTIDRUG RESISTANCE PROTEIN 2;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CLONE; CONTROLLED STUDY; DNA BINDING; GENE CONTROL; GENE DELETION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; MOLECULAR MECHANICS; MUTAGENESIS; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION;

5' FLANKING REGION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; CCAAT-ENHANCER-BINDING PROTEINS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; DEXAMETHASONE; GENES, REPORTER; GLUCOCORTICOIDS; HELA CELLS; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTE NUCLEAR FACTOR 6; HEPATOCYTE NUCLEAR FACTORS; HEPATOCYTES; HUMANS; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; RATS; TRANSCRIPTION, GENETIC; TRANSFECTION;

MAMMALIA;

EID: 58649088927     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.10.005     Document Type: Article

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