-
1
-
-
13244292389
-
Protective effects of insulin-like growth factor-I on the somatostatinergic system in the temporal cortex of β-amyloid-treated rats
-
Aguado-Llera D., Arilla-Ferreiro E., Campos-Barros A., Puebla-Jimenez L., and Barrios V. Protective effects of insulin-like growth factor-I on the somatostatinergic system in the temporal cortex of β-amyloid-treated rats. J. Neurochem. 92 3 (2005) 607-615
-
(2005)
J. Neurochem.
, vol.92
, Issue.3
, pp. 607-615
-
-
Aguado-Llera, D.1
Arilla-Ferreiro, E.2
Campos-Barros, A.3
Puebla-Jimenez, L.4
Barrios, V.5
-
2
-
-
0032859938
-
Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death
-
Alvarez A., Toro R., Caceres A., and Maccioni R.B. Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death. FEBS Lett. 459 3 (1999) 421-426
-
(1999)
FEBS Lett.
, vol.459
, Issue.3
, pp. 421-426
-
-
Alvarez, A.1
Toro, R.2
Caceres, A.3
Maccioni, R.B.4
-
3
-
-
0030664286
-
Transport of insulin across the blood-brain barrier: saturability at euglycemic doses of insulin
-
Banks W.A., Jaspan J.B., Huang W., and Kastin A.J. Transport of insulin across the blood-brain barrier: saturability at euglycemic doses of insulin. Peptides 18 9 (1997) 1423-1429
-
(1997)
Peptides
, vol.18
, Issue.9
, pp. 1423-1429
-
-
Banks, W.A.1
Jaspan, J.B.2
Huang, W.3
Kastin, A.J.4
-
4
-
-
0033696622
-
Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD
-
Beattie E.C., Carroll R.C., Yu X., Morishita W., Yasuda H., von Zastrow M., and Malenka R.C. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nat. Neurosci. 3 12 (2000) 1291-1300
-
(2000)
Nat. Neurosci.
, vol.3
, Issue.12
, pp. 1291-1300
-
-
Beattie, E.C.1
Carroll, R.C.2
Yu, X.3
Morishita, W.4
Yasuda, H.5
von Zastrow, M.6
Malenka, R.C.7
-
6
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
Chapman P.F., White G.L., Jones M.W., Cooper-Blacketer D., Marshall V.J., Irizarry M., Younkin L., Good M.A., Bliss T.V., Hyman B.T., Younkin S.G., and Hsiao K.K. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat. Neurosci. 2 3 (1999) 271-276
-
(1999)
Nat. Neurosci.
, vol.2
, Issue.3
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
Cooper-Blacketer, D.4
Marshall, V.J.5
Irizarry, M.6
Younkin, L.7
Good, M.A.8
Bliss, T.V.9
Hyman, B.T.10
Younkin, S.G.11
Hsiao, K.K.12
-
7
-
-
0034069795
-
Impairment of hippocampal long-term potentiation by Alzheimer amyloid β-peptides
-
Chen Q.S., Kagan B.L., Hirakura Y., and Xie C.W. Impairment of hippocampal long-term potentiation by Alzheimer amyloid β-peptides. J. Neurosci. Res. 60 1 (2000) 65-72
-
(2000)
J. Neurosci. Res.
, vol.60
, Issue.1
, pp. 65-72
-
-
Chen, Q.S.1
Kagan, B.L.2
Hirakura, Y.3
Xie, C.W.4
-
8
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype
-
Craft S., Peskind E., Schwartz M.W., Schellenberg G.D., Raskind M., and Porte Jr. D. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 50 1 (1998) 164-168
-
(1998)
Neurology
, vol.50
, Issue.1
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
Schellenberg, G.D.4
Raskind, M.5
Porte Jr., D.6
-
9
-
-
1042265187
-
Neuropathology and pathogenesis of encephalitis following amyloid-β immunization in Alzheimer's disease
-
Ferrer I., Boada Rovira M., Sanchez Guerra M.L., Rey M.J., and Costa-Jussa F. Neuropathology and pathogenesis of encephalitis following amyloid-β immunization in Alzheimer's disease. Brain Pathol. 14 1 (2004) 11-20
-
(2004)
Brain Pathol.
, vol.14
, Issue.1
, pp. 11-20
-
-
Ferrer, I.1
Boada Rovira, M.2
Sanchez Guerra, M.L.3
Rey, M.J.4
Costa-Jussa, F.5
-
10
-
-
0038581893
-
1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo
-
1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo. J. Neurophysiol. 89 6 (2003) 2917-2922
-
(2003)
J. Neurophysiol.
, vol.89
, Issue.6
, pp. 2917-2922
-
-
Freir, D.B.1
Herron, C.E.2
-
11
-
-
0035128734
-
Blockade of long-term potentiation by β-amyloid peptides in the CA1 region of the rat hippocampus in vivo
-
Freir D.B., Holscher C., and Herron C.E. Blockade of long-term potentiation by β-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J. Neurophysiol. 85 2 (2001) 708-713
-
(2001)
J. Neurophysiol.
, vol.85
, Issue.2
, pp. 708-713
-
-
Freir, D.B.1
Holscher, C.2
Herron, C.E.3
-
12
-
-
0035871641
-
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L., Gouras G.K., Wang R., Gross R.S., Beal M.F., Greengard P., and Xu H. Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling. J. Neurosci. 21 8 (2001) 2561-2570
-
(2001)
J. Neurosci.
, vol.21
, Issue.8
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
Xu, H.7
-
13
-
-
0036591657
-
Does insulin dysfunction play a role in Alzheimer's disease?
-
Gasparini L., Netzer W.J., Greengard P., and Xu H. Does insulin dysfunction play a role in Alzheimer's disease?. Trends Pharmacol. Sci. 23 6 (2002) 288-293
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, Issue.6
, pp. 288-293
-
-
Gasparini, L.1
Netzer, W.J.2
Greengard, P.3
Xu, H.4
-
14
-
-
0142026832
-
Potential roles of insulin and IGF-1 in Alzheimer's disease
-
Gasparini L., and Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci. 26 8 (2003) 404-406
-
(2003)
Trends Neurosci.
, vol.26
, Issue.8
, pp. 404-406
-
-
Gasparini, L.1
Xu, H.2
-
15
-
-
34249024370
-
Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background
-
Gengler S., Gault V.A., Harriott P., and Holscher C. Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background. Exp. Brain Res. 179 4 (2007) 621-630
-
(2007)
Exp. Brain Res.
, vol.179
, Issue.4
, pp. 621-630
-
-
Gengler, S.1
Gault, V.A.2
Harriott, P.3
Holscher, C.4
-
16
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner G.G., and Wong C.W. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun. 122 3 (1984) 1131-1135
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, Issue.3
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
17
-
-
0023009658
-
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments
-
Grundke-Iqbal I., Iqbal K., Quinlan M., Tung Y.C., Zaidi M.S., and Wisniewski H.M. Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J. Biol. Chem. 261 13 (1986) 6084-6089
-
(1986)
J. Biol. Chem.
, vol.261
, Issue.13
, pp. 6084-6089
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Quinlan, M.3
Tung, Y.C.4
Zaidi, M.S.5
Wisniewski, H.M.6
-
18
-
-
0033043939
-
p38 kinase is activated in the Alzheimer's disease brain
-
Hensley K., Floyd R.A., Zheng N.Y., Nael R., Robinson K.A., Nguyen X., Pye Q.N., Stewart C.A., Geddes J., Markesbery W.R., Patel E., Johnson G.V., and Bing G. p38 kinase is activated in the Alzheimer's disease brain. J. Neurochem. 72 5 (1999) 2053-2058
-
(1999)
J. Neurochem.
, vol.72
, Issue.5
, pp. 2053-2058
-
-
Hensley, K.1
Floyd, R.A.2
Zheng, N.Y.3
Nael, R.4
Robinson, K.A.5
Nguyen, X.6
Pye, Q.N.7
Stewart, C.A.8
Geddes, J.9
Markesbery, W.R.10
Patel, E.11
Johnson, G.V.12
Bing, G.13
-
19
-
-
0022510796
-
Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas
-
Hill J.M., Lesniak M.A., Pert C.B., and Roth J. Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 17 4 (1986) 1127-1138
-
(1986)
Neuroscience
, vol.17
, Issue.4
, pp. 1127-1138
-
-
Hill, J.M.1
Lesniak, M.A.2
Pert, C.B.3
Roth, J.4
-
20
-
-
0033571910
-
A role for extracellular adenosine in time-dependent reversal of long-term potentiation by low-frequency stimulation at hippocampal CA1 synapses
-
Huang C.C., Liang Y.C., and Hsu K.S. A role for extracellular adenosine in time-dependent reversal of long-term potentiation by low-frequency stimulation at hippocampal CA1 synapses. J. Neurosci. 19 22 (1999) 9728-9738
-
(1999)
J. Neurosci.
, vol.19
, Issue.22
, pp. 9728-9738
-
-
Huang, C.C.1
Liang, Y.C.2
Hsu, K.S.3
-
21
-
-
1842562359
-
An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus
-
Huang C.C., Lee C.C., and Hsu K.S. An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus. J. Neurochem. 89 1 (2004) 217-231
-
(2004)
J. Neurochem.
, vol.89
, Issue.1
, pp. 217-231
-
-
Huang, C.C.1
Lee, C.C.2
Hsu, K.S.3
-
22
-
-
32644483115
-
Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of (S)-3,5-dihydroxyphenylglycine-induced long-term depression in the hippocampal CA1 region
-
Huang C.C., and Hsu K.S. Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of (S)-3,5-dihydroxyphenylglycine-induced long-term depression in the hippocampal CA1 region. J. Neurochem. 96 1 (2006) 179-194
-
(2006)
J. Neurochem.
, vol.96
, Issue.1
, pp. 179-194
-
-
Huang, C.C.1
Hsu, K.S.2
-
23
-
-
25844477102
-
Current concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer's disease
-
Jacobsen J.S., Reinhart P., and Pangalos M.N. Current concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer's disease. NeuroRx 2 4 (2005) 612-626
-
(2005)
NeuroRx
, vol.2
, Issue.4
, pp. 612-626
-
-
Jacobsen, J.S.1
Reinhart, P.2
Pangalos, M.N.3
-
24
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., and Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300 5618 (2003) 486-489
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
25
-
-
21044453723
-
Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I., Walsh D.M., Lemere C.A., Cullen W.K., Shankar G.M., Betts V., Spooner E.T., Jiang L., Anwyl R., Selkoe D.J., and Rowan M.J. Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo. Nat. Med. 11 5 (2005) 556-561
-
(2005)
Nat. Med.
, vol.11
, Issue.5
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
Spooner, E.T.7
Jiang, L.8
Anwyl, R.9
Selkoe, D.J.10
Rowan, M.J.11
-
26
-
-
0032496368
-
Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme
-
Kurochkin I.V. Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme. FEBS Lett. 427 2 (1998) 153-156
-
(1998)
FEBS Lett.
, vol.427
, Issue.2
, pp. 153-156
-
-
Kurochkin, I.V.1
-
27
-
-
17044439021
-
Alzheimer's disease: Aβ, tau and synaptic dysfunction
-
LaFerla F.M., and Oddo S. Alzheimer's disease: Aβ, tau and synaptic dysfunction. Trends Mol. Med. 11 4 (2005) 170-176
-
(2005)
Trends Mol. Med.
, vol.11
, Issue.4
, pp. 170-176
-
-
LaFerla, F.M.1
Oddo, S.2
-
28
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U.S.A. 95 11 (1998) 6448-6453
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
29
-
-
0034682414
-
Neurotoxicity induces cleavage of p35 to p25 by calpain
-
Lee M.S., Kwon Y.T., Li M., Peng J., Friedlander R.M., and Tsai L.H. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 405 6784 (2000) 360-364
-
(2000)
Nature
, vol.405
, Issue.6784
, pp. 360-364
-
-
Lee, M.S.1
Kwon, Y.T.2
Li, M.3
Peng, J.4
Friedlander, R.M.5
Tsai, L.H.6
-
30
-
-
0030663143
-
The risk of dementia among persons with diabetes mellitus: a population-based cohort study
-
Leibson C.L., Rocca W.A., Hanson V.A., Cha R., Kokmen E., O'Brien P.C., and Palumbo P.J. The risk of dementia among persons with diabetes mellitus: a population-based cohort study. Ann. N. Y. Acad. Sci. 826 (1997) 422-427
-
(1997)
Ann. N. Y. Acad. Sci.
, vol.826
, pp. 422-427
-
-
Leibson, C.L.1
Rocca, W.A.2
Hanson, V.A.3
Cha, R.4
Kokmen, E.5
O'Brien, P.C.6
Palumbo, P.J.7
-
31
-
-
0027502784
-
Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: detection of amyloid aggregation in solution
-
LeVine III H. Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci. 2 3 (1993) 404-410
-
(1993)
Protein Sci.
, vol.2
, Issue.3
, pp. 404-410
-
-
LeVine III, H.1
-
32
-
-
0033695663
-
Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization
-
Lin J.W., Ju W., Foster K., Lee S.H., Ahmadian G., Wyszynski M., Wang Y.T., and Sheng M. Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization. Nat. Neurosci. 3 12 (2000) 1282-1290
-
(2000)
Nat. Neurosci.
, vol.3
, Issue.12
, pp. 1282-1290
-
-
Lin, J.W.1
Ju, W.2
Foster, K.3
Lee, S.H.4
Ahmadian, G.5
Wyszynski, M.6
Wang, Y.T.7
Sheng, M.8
-
33
-
-
0346099098
-
Residues 17-20 and 30-35 of β-amyloid play critical roles in aggregation
-
Liu R., McAllister C., Lyubchenko Y., and Sierks M.R. Residues 17-20 and 30-35 of β-amyloid play critical roles in aggregation. J. Neurosci. Res. 75 2 (2004) 162-171
-
(2004)
J. Neurosci. Res.
, vol.75
, Issue.2
, pp. 162-171
-
-
Liu, R.1
McAllister, C.2
Lyubchenko, Y.3
Sierks, M.R.4
-
34
-
-
0033681557
-
Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
-
Man H.Y., Lin J.W., Ju W.H., Ahmadian G., Liu L., Becker L.E., Sheng M., and Wang Y.T. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25 3 (2000) 649-662
-
(2000)
Neuron
, vol.25
, Issue.3
, pp. 649-662
-
-
Man, H.Y.1
Lin, J.W.2
Ju, W.H.3
Ahmadian, G.4
Liu, L.5
Becker, L.E.6
Sheng, M.7
Wang, Y.T.8
-
35
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters C.L., Simms G., Weinman N.A., Multhaup G., McDonald B.L., and Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. U.S.A. 82 12 (1985) 4245-4249
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, Issue.12
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
36
-
-
0032526423
-
β-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes
-
McDonald D.R., Bamberger M.E., Combs C.K., and Landreth G.E. β-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes. J. Neurosci. 18 12 (1998) 4451-4460
-
(1998)
J. Neurosci.
, vol.18
, Issue.12
, pp. 4451-4460
-
-
McDonald, D.R.1
Bamberger, M.E.2
Combs, C.K.3
Landreth, G.E.4
-
37
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantoglu J., Tirado-Santiago G., Lahsaini A., Poirier J., Goncalves O., Verge G., Momoli F., Welner S.A., Massicotte G., Julien J.P., and Shapiro M.L. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature 387 6632 (1997) 500-505
-
(1997)
Nature
, vol.387
, Issue.6632
, pp. 500-505
-
-
Nalbantoglu, J.1
Tirado-Santiago, G.2
Lahsaini, A.3
Poirier, J.4
Goncalves, O.5
Verge, G.6
Momoli, F.7
Welner, S.A.8
Massicotte, G.9
Julien, J.P.10
Shapiro, M.L.11
-
38
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report
-
Nicoll J.A., Wilkinson D., Holmes C., Steart P., Markham H., and Weller R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat. Med. 9 4 (2003) 448-452
-
(2003)
Nat. Med.
, vol.9
, Issue.4
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
39
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A., Stolk R.P., van Harskamp F., Pols H.A., Hofman A., and Breteler M.M. Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 53 9 (1999) 1937-1942
-
(1999)
Neurology
, vol.53
, Issue.9
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
40
-
-
0028981219
-
Structure-activity analyses of β-amyloid peptides: contributions of the β 25-35 region to aggregation and neurotoxicity
-
Pike C.J., Walencewicz-Wasserman A.J., Kosmoski J., Cribbs D.H., Glabe C.G., and Cotman C.W. Structure-activity analyses of β-amyloid peptides: contributions of the β 25-35 region to aggregation and neurotoxicity. J. Neurochem. 64 1 (1995) 253-265
-
(1995)
J. Neurochem.
, vol.64
, Issue.1
, pp. 253-265
-
-
Pike, C.J.1
Walencewicz-Wasserman, A.J.2
Kosmoski, J.3
Cribbs, D.H.4
Glabe, C.G.5
Cotman, C.W.6
-
42
-
-
0028301348
-
Macromolecular permeability across the blood-nerve and blood-brain barriers
-
Poduslo J.F., Curran G.L., and Berg C.T. Macromolecular permeability across the blood-nerve and blood-brain barriers. Proc. Natl. Acad. Sci. U.S.A. 91 12 (1994) 5705-5709
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, Issue.12
, pp. 5705-5709
-
-
Poduslo, J.F.1
Curran, G.L.2
Berg, C.T.3
-
43
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis
-
Qiu W.Q., and Folstein M.F. Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis. Neurobiol. Aging 27 2 (2006) 190-198
-
(2006)
Neurobiol. Aging
, vol.27
, Issue.2
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
44
-
-
0034711277
-
Activation of insulin signal transduction pathway and anti-diabetic activity of small molecule insulin receptor activators
-
Qureshi S.A., Ding V., Li Z., Szalkowski D., Biazzo-Ashnault D.E., Xie D., Saperstein R., Brady E., Huskey S., Shen X., Liu K., Xu L., Salituro G.M., Heck J.V., Moller D.E., Jones A.B., and Zhang B.B. Activation of insulin signal transduction pathway and anti-diabetic activity of small molecule insulin receptor activators. J. Biol. Chem. 275 47 (2000) 36590-36595
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.47
, pp. 36590-36595
-
-
Qureshi, S.A.1
Ding, V.2
Li, Z.3
Szalkowski, D.4
Biazzo-Ashnault, D.E.5
Xie, D.6
Saperstein, R.7
Brady, E.8
Huskey, S.9
Shen, X.10
Liu, K.11
Xu, L.12
Salituro, G.M.13
Heck, J.V.14
Moller, D.E.15
Jones, A.B.16
Zhang, B.B.17
-
45
-
-
0346220380
-
Insulin inhibits amyloid β-induced cell death in cultured human brain pericytes
-
Rensink A.A., Otte-Holler I., de Boer R., Bosch R.R., ten Donkelaar H.J., de Waal R.M., Verbeek M.M., and Kremer B. Insulin inhibits amyloid β-induced cell death in cultured human brain pericytes. Neurobiol. Aging 25 1 (2004) 93-103
-
(2004)
Neurobiol. Aging
, vol.25
, Issue.1
, pp. 93-103
-
-
Rensink, A.A.1
Otte-Holler, I.2
de Boer, R.3
Bosch, R.R.4
ten Donkelaar, H.J.5
de Waal, R.M.6
Verbeek, M.M.7
Kremer, B.8
-
46
-
-
31844434789
-
Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype
-
Reger M.A., Watson G.S., Frey II W.H., Baker L.D., Cholerton B., Keeling M.L., Belongia D.A., Fishel M.A., Plymate S.R., Schellenberg G.D., Cherrier M.M., and Craft S. Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype. Neurobiol. Aging 27 3 (2006) 451-458
-
(2006)
Neurobiol. Aging
, vol.27
, Issue.3
, pp. 451-458
-
-
Reger, M.A.1
Watson, G.S.2
Frey II, W.H.3
Baker, L.D.4
Cholerton, B.5
Keeling, M.L.6
Belongia, D.A.7
Fishel, M.A.8
Plymate, S.R.9
Schellenberg, G.D.10
Cherrier, M.M.11
Craft, S.12
-
47
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., and Seubert P. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400 6740 (1999) 173-177
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
48
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe D.J. Clearing the brain's amyloid cobwebs. Neuron 32 2 (2001) 177-180
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 177-180
-
-
Selkoe, D.J.1
-
49
-
-
0001181116
-
Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
-
Selkoe D.J., and Schenk D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu. Rev. Pharmacol. Toxicol. 43 (2003) 545-584
-
(2003)
Annu. Rev. Pharmacol. Toxicol.
, vol.43
, pp. 545-584
-
-
Selkoe, D.J.1
Schenk, D.2
-
50
-
-
0034727889
-
JNK activation is associated with intracellular β-amyloid accumulation
-
Shoji M., Iwakami N., Takeuchi S., Waragai M., Suzuki M., Kanazawa I., Lippa C.F., Ono S., and Okazawa H. JNK activation is associated with intracellular β-amyloid accumulation. Brain Res. Mol. Brain Res. 85 1-2 (2000) 221-233
-
(2000)
Brain Res. Mol. Brain Res.
, vol.85
, Issue.1-2
, pp. 221-233
-
-
Shoji, M.1
Iwakami, N.2
Takeuchi, S.3
Waragai, M.4
Suzuki, M.5
Kanazawa, I.6
Lippa, C.F.7
Ono, S.8
Okazawa, H.9
-
52
-
-
33645505550
-
Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers
-
Townsend M., Shankar G.M., Mehta T., Walsh D.M., and Selkoe D.J. Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers. J. Physiol. 572 2 (2006) 477-492
-
(2006)
J. Physiol.
, vol.572
, Issue.2
, pp. 477-492
-
-
Townsend, M.1
Shankar, G.M.2
Mehta, T.3
Walsh, D.M.4
Selkoe, D.J.5
-
53
-
-
0035076483
-
β-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation
-
Troy C.M., Rabacchi S.A., Xu Z., Maroney A.C., Connors T.J., Shelanski M.L., and Greene L.A. β-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. J. Neurochem. 77 1 (2001) 157-164
-
(2001)
J. Neurochem.
, vol.77
, Issue.1
, pp. 157-164
-
-
Troy, C.M.1
Rabacchi, S.A.2
Xu, Z.3
Maroney, A.C.4
Connors, T.J.5
Shelanski, M.L.6
Greene, L.A.7
-
54
-
-
0037041426
-
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., and Selkoe D.J. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416 6880 (2002) 535-539
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
55
-
-
0030799122
-
Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate
-
Walsh D.M., Lomakin A., Benedek G.B., Condron M.M., and Teplow D.B. Amyloid β-protein fibrillogenesis. Detection of a protofibrillar intermediate. J. Biol. Chem. 272 35 (1997) 22364-22372
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.35
, pp. 22364-22372
-
-
Walsh, D.M.1
Lomakin, A.2
Benedek, G.B.3
Condron, M.M.4
Teplow, D.B.5
-
56
-
-
14944378094
-
Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation
-
Walsh D.M., Townsend M., Podlisny M.B., Shankar G.M., Fadeeva J.V., Agnaf O.E., Hartley D.M., and Selkoe D.J. Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation. J. Neurosci. 25 10 (2005) 2455-2462
-
(2005)
J. Neurosci.
, vol.25
, Issue.10
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
Shankar, G.M.4
Fadeeva, J.V.5
Agnaf, O.E.6
Hartley, D.M.7
Selkoe, D.J.8
-
57
-
-
1842610852
-
Block of long-term potentiation by naturally secreted and synthetic amyloid β-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
-
Wang Q., Walsh D.M., Rowan M.J., Selkoe D.J., and Anwyl R. Block of long-term potentiation by naturally secreted and synthetic amyloid β-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5. J. Neurosci. 24 13 (2004) 3370-3378
-
(2004)
J. Neurosci.
, vol.24
, Issue.13
, pp. 3370-3378
-
-
Wang, Q.1
Walsh, D.M.2
Rowan, M.J.3
Selkoe, D.J.4
Anwyl, R.5
-
58
-
-
0032562694
-
Tracking insulin to the mind
-
Wickelgren I. Tracking insulin to the mind. Science 280 5363 (1998) 517-519
-
(1998)
Science
, vol.280
, Issue.5363
, pp. 517-519
-
-
Wickelgren, I.1
-
59
-
-
0027391758
-
The cellular and physiological actions of insulin in the central nervous system
-
Wozniak M., Rydzewski B., Baker S.P., and Raizada M.K. The cellular and physiological actions of insulin in the central nervous system. Neurochem. Int. 22 1 (1993) 1-10
-
(1993)
Neurochem. Int.
, vol.22
, Issue.1
, pp. 1-10
-
-
Wozniak, M.1
Rydzewski, B.2
Baker, S.P.3
Raizada, M.K.4
-
60
-
-
9644302450
-
Hemoglobin promotes Aβ oligomer formation and localizes in neurons and amyloid deposits
-
Wu C.W., Liao P.C., Yu L., Wang S.T., Chen S.T., Wu C.M., and Kuo Y.M. Hemoglobin promotes Aβ oligomer formation and localizes in neurons and amyloid deposits. Neurobiol. Dis. 17 3 (2004) 367-377
-
(2004)
Neurobiol. Dis.
, vol.17
, Issue.3
, pp. 367-377
-
-
Wu, C.W.1
Liao, P.C.2
Yu, L.3
Wang, S.T.4
Chen, S.T.5
Wu, C.M.6
Kuo, Y.M.7
-
61
-
-
18744438248
-
Alzheimer's β-amyloid peptides compete for insulin binding to the insulin receptor
-
Xie L., Helmerhorst E., Taddei K., Plewright B., Van Bronswijk W., and Martins R. Alzheimer's β-amyloid peptides compete for insulin binding to the insulin receptor. J. Neurosci. 22 10 (2002) RC221
-
(2002)
J. Neurosci.
, vol.22
, Issue.10
-
-
Xie, L.1
Helmerhorst, E.2
Taddei, K.3
Plewright, B.4
Van Bronswijk, W.5
Martins, R.6
-
62
-
-
0033532347
-
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
-
Zhang B., Salituro G., Szalkowski D., Li Z., Zhang Y., Royo I., Vilella D., Diez M.T., Pelaez F., Ruby C., Kendall R.L., Mao X., Griffin P., Calaycay J., Zierath J.R., Heck J.V., Smith R.G., and Moller D.E. Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science 284 5416 (1999) 974-977
-
(1999)
Science
, vol.284
, Issue.5416
, pp. 974-977
-
-
Zhang, B.1
Salituro, G.2
Szalkowski, D.3
Li, Z.4
Zhang, Y.5
Royo, I.6
Vilella, D.7
Diez, M.T.8
Pelaez, F.9
Ruby, C.10
Kendall, R.L.11
Mao, X.12
Griffin, P.13
Calaycay, J.14
Zierath, J.R.15
Heck, J.V.16
Smith, R.G.17
Moller, D.E.18
-
63
-
-
0035142804
-
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
-
Zhu X., Raina A.K., Rottkamp C.A., Aliev G., Perry G., Boux H., and Smith M.A. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76 2 (2001) 435-441
-
(2001)
J. Neurochem.
, vol.76
, Issue.2
, pp. 435-441
-
-
Zhu, X.1
Raina, A.K.2
Rottkamp, C.A.3
Aliev, G.4
Perry, G.5
Boux, H.6
Smith, M.A.7
|