메뉴 건너뛰기




Volumn , Issue , 2008, Pages 163-185

Steroid-Sparing Strategies: Long-Acting Inhaled β2-Agonists

Author keywords

Budesonide formoterol (BUD FORM); Chronic obstructive pulmonary disease (COPD); Hypothalamic pituitary adrenal (HPA) axis; Long acting inhaled 2 agonists (LABA); Salmeterol fluticasone (SALM FP)

Indexed keywords


EID: 58349120261     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470985731.ch10     Document Type: Chapter
Times cited : (1)

References (121)
  • 1
    • 1042279583 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/formoterol improves asthma control compared with fi xeddose salmeterol/fl uticasone
    • Aalbers R, Backer V, Kava TTK, Omenaas ER, Sandström T, Jorup C, Welte T. Adjustable maintenance dosing with budesonide/formoterol improves asthma control compared with fi xeddose salmeterol/fl uticasone. Curr Med Res Opin 2004; 20: 225-240.
    • (2004) Curr Med Res Opin , vol.20 , pp. 225-240
    • Aalbers, R.1    Backer, V.2    Kava, T.T.K.3    Omenaas, E.R.4    Sandström, T.5    Jorup, C.6    Welte, T.7
  • 2
    • 0032982717 scopus 로고    scopus 로고
    • Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-?B and lack of I-?B involvement
    • Adcock IM, Nasuhara Y, Stevens DA, Barnes PJ. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-?B and lack of I-?B involvement. Br J Pharmacol 1999; 127: 1003-10011.
    • (1999) Br J Pharmacol , vol.127 , pp. 1003-10011
    • Adcock, I.M.1    Nasuhara, Y.2    Stevens, D.A.3    Barnes, P.J.4
  • 4
    • 33846104450 scopus 로고    scopus 로고
    • Effects of salmeterol xinafoate and fl uticasone propionate on immunological activation of human cultured mast cells
    • Akabane H, Murata M, Kufota M, Takashima E, Tanaka H, Inagaki N, Horifa M, Nagai H. Effects of salmeterol xinafoate and fl uticasone propionate on immunological activation of human cultured mast cells. Allergol Int 2006; 55: 387-393.
    • (2006) Allergol Int , vol.55 , pp. 387-393
    • Akabane, H.1    Murata, M.2    Kufota, M.3    Takashima, E.4    Tanaka, H.5    Inagaki, N.6    Horifa, M.7    Nagai, H.8
  • 5
    • 0036009461 scopus 로고    scopus 로고
    • Tumor necrosis factor-a-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists
    • Ammit AJ, Lazaar AL, Irani C, O'Neill GM et al. Tumor necrosis factor-a-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol 2002; 26: 465-474.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 465-474
    • Ammit, A.J.1    Lazaar, A.L.2    Irani, C.3    O'Neill, G.M.4
  • 6
    • 28744445466 scopus 로고    scopus 로고
    • Combination inhalers containing inhaled corticosteroids and long-acting ß2-agonists: improved clinical effi cacy and dosing options in patients with asthma
    • Ankerst J. Combination inhalers containing inhaled corticosteroids and long-acting ß2-agonists: improved clinical effi cacy and dosing options in patients with asthma. J Asthma 2005; 42: 715-724.
    • (2005) J Asthma , vol.42 , pp. 715-724
    • Ankerst, J.1
  • 7
    • 27744441314 scopus 로고    scopus 로고
    • Lung myofi broblasts as targets of salmeterol and fl uticasone propionate: inhibition of a-SMA and NF-?B
    • Baouz S, Giron-Michel J, Azzarone B, Giuliani M et al. Lung myofi broblasts as targets of salmeterol and fl uticasone propionate: inhibition of a-SMA and NF-?B. Int Immunol 2005; 17: 1473-1481.
    • (2005) Int Immunol , vol.17 , pp. 1473-1481
    • Baouz, S.1    Giron-Michel, J.2    Azzarone, B.3    Giuliani, M.4
  • 8
    • 0032820252 scopus 로고    scopus 로고
    • Fluticasone alone or in combination with salmeterol versus triamcinolone in asthma
    • Baraniuk J, Murray JJ, Nathan RA, Berger WE et al. Fluticasone alone or in combination with salmeterol versus triamcinolone in asthma. Chest 1999; 116: 625-632.
    • (1999) Chest , vol.116 , pp. 625-632
    • Baraniuk, J.1    Murray, J.J.2    Nathan, R.A.3    Berger, W.E.4
  • 9
    • 23044502066 scopus 로고    scopus 로고
    • Corticosteroid resistance in airway disease
    • Barnes PJ. Corticosteroid resistance in airway disease Proc Am Thorac Soc 2004; 1: 264-268.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 264-268
    • Barnes, P.J.1
  • 10
    • 14744285888 scopus 로고    scopus 로고
    • Histone acetylation and deacetylation: importance in infl ammatory lung diseases
    • Barnes PJ, Adcock IM, Ito K. Histone acetylation and deacetylation: importance in infl ammatory lung diseases. Eur Respir J 2005; 25: 552-563.
    • (2005) Eur Respir J , vol.25 , pp. 552-563
    • Barnes, P.J.1    Adcock, I.M.2    Ito, K.3
  • 12
    • 0038266131 scopus 로고    scopus 로고
    • Combination therapy with single inhaler budesonide/formoterol compared with high dose of fl uticasone propionate alone in patients with moderate persistent asthma
    • Bateman ED, Bantje TA, Joao Gomes M, Toumbis M, Huber R, Naya I, Eliraz A. Combination therapy with single inhaler budesonide/formoterol compared with high dose of fl uticasone propionate alone in patients with moderate persistent asthma. Am J Respir Med 2003; 2: 275-281.
    • (2003) Am J Respir Med , vol.2 , pp. 275-281
    • Bateman, E.D.1    Bantje, T.A.2    Joao Gomes, M.3    Toumbis, M.4    Huber, R.5    Naya, I.6    Eliraz, A.7
  • 13
    • 26144471319 scopus 로고    scopus 로고
    • Rhinovirus infection reduces glucocorticoid receptor nuclear translocation in airway epithelial cells
    • Bellettato C, Adcock IM, Ito K, Caramori G et al. Rhinovirus infection reduces glucocorticoid receptor nuclear translocation in airway epithelial cells. Am J Respir Crit Care Med 2003; 167: A578.
    • (2003) Am J Respir Crit Care Med , vol.167
    • Bellettato, C.1    Adcock, I.M.2    Ito, K.3    Caramori, G.4
  • 14
    • 33845928663 scopus 로고    scopus 로고
    • Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma
    • Bisgaard H, LeRoux P, Bjåmer D, Dymek A, Vermeulen JH, Hultquist C. Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma. Chest 2006; 130: 1733-1743.
    • (2006) Chest , vol.130 , pp. 1733-1743
    • Bisgaard, H.1    Leroux, P.2    Bjåmer, D.3    Dymek, A.4    Vermeulen, J.H.5    Hultquist, C.6
  • 15
    • 24744458727 scopus 로고    scopus 로고
    • Fluticasone propionate/salmeterol 100/50 mcg is inhaled steroid sparing in patients who require fl uticasone propionate 250 mcg for asthma stability
    • Bloom J, Calhoun W, Koenig S, Yancey S et al. Fluticasone propionate/salmeterol 100/50 mcg is inhaled steroid sparing in patients who require fl uticasone propionate 250 mcg for asthma stability. Am J Respir Crit Care Med 2003; 167: A891.
    • (2003) Am J Respir Crit Care Med , vol.167
    • Bloom, J.1    Calhoun, W.2    Koenig, S.3    Yancey, S.4
  • 16
    • 0043136462 scopus 로고    scopus 로고
    • Budesonide/formoterol for the treatment of asthma
    • Buhl R. Budesonide/formoterol for the treatment of asthma. Expert Opin Pharmacother 2003; 4: 1393-1406.
    • (2003) Expert Opin Pharmacother , vol.4 , pp. 1393-1406
    • Buhl, R.1
  • 17
    • 4344664690 scopus 로고    scopus 로고
    • The effect of adjustable dosing with budesonide/formoterol on health-related quality of life and asthma control compared with fi xed dosing
    • Buhl R, Kardos P, Richter K, Meyer-Sabellek W, Brüggenjürgen B, Willich SN, Vogelmeier C. The effect of adjustable dosing with budesonide/formoterol on health-related quality of life and asthma control compared with fi xed dosing. Curr Med Res Opin 2004; 20: 1209-1220.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1209-1220
    • Buhl, R.1    Kardos, P.2    Richter, K.3    Meyer-Sabellek, W.4    Brüggenjürgen, B.5    Willich, S.N.6    Vogelmeier, C.7
  • 18
    • 0031958895 scopus 로고    scopus 로고
    • Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adults with chronic asthma
    • Busse WW, Chervinsky P, Condemi J, Lumry WR, Petty TL, Rennard S, Townley RG. Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adults with chronic asthma. J Allergy Clin Immunol 1998; 101: 457-463.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 457-463
    • Busse, W.W.1    Chervinsky, P.2    Condemi, J.3    Lumry, W.R.4    Petty, T.L.5    Rennard, S.6    Townley, R.G.7
  • 19
    • 0037247229 scopus 로고    scopus 로고
    • Steroid-sparing effects of fl uticasone propionate 100 μg and salmeterol 50 μg administered twice daily in a single product in patients previously controlled with fl uticasone propionate 250 μg administered twice daily
    • Busse W, Koenig SM, Oppenheimer J, Sahn SA et al. Steroid-sparing effects of fl uticasone propionate 100 μg and salmeterol 50 μg administered twice daily in a single product in patients previously controlled with fl uticasone propionate 250 μg administered twice daily. J Allergy Clin Immunol 2003; 111: 57-65.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 57-65
    • Busse, W.1    Koenig, S.M.2    Oppenheimer, J.3    Sahn, S.A.4
  • 20
    • 0347473812 scopus 로고    scopus 로고
    • Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
    • Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H. Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003; 22: 912-919.
    • (2003) Eur Respir J , vol.22 , pp. 912-919
    • Calverley, P.M.1    Boonsawat, W.2    Cseke, Z.3    Zhong, N.4    Peterson, S.5    Olsson, H.6
  • 21
    • 3042674380 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/formoterol in a single inhaler provides effective asthma symptom control at a lower dose than fi xed maintenance dosing
    • Canonica GW, Castellani P, Cazzola M, Fabbri LM et al. Adjustable maintenance dosing with budesonide/formoterol in a single inhaler provides effective asthma symptom control at a lower dose than fi xed maintenance dosing. Pulm Pharmacol Ther 2004; 17: 239-247.
    • (2004) Pulm Pharmacol Ther , vol.17 , pp. 239-247
    • Canonica, G.W.1    Castellani, P.2    Cazzola, M.3    Fabbri, L.M.4
  • 22
    • 0041802817 scopus 로고    scopus 로고
    • Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways
    • Clark AR, Lasa M. Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways. Curr Opin Pharmacol 2003; 3: 404-411.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 404-411
    • Clark, A.R.1    Lasa, M.2
  • 23
    • 33748446393 scopus 로고    scopus 로고
    • Role of defi cient type III interferonlambda production in asthma exacerbations
    • Contoli M, Message SD, Laza-Stanca V, Edwards MR et al. Role of defi cient type III interferonlambda production in asthma exacerbations. Nat Med 2006; 12: 1023-1026.
    • (2006) Nat Med , vol.12 , pp. 1023-1026
    • Contoli, M.1    Message, S.D.2    Laza-Stanca, V.3    Edwards, M.R.4
  • 24
    • 33646452550 scopus 로고    scopus 로고
    • Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells
    • Edwards MR, Johnson MW, Johnston SL. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. Am J Respir Cell Mol Biol 2006; 34: 616-624.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 616-624
    • Edwards, M.R.1    Johnson, M.W.2    Johnston, S.L.3
  • 25
    • 0033534727 scopus 로고    scopus 로고
    • Ligand-independent activation of the glucocorticoid receptor by ß2-adrenergic receptor agonists in primary human lung fi broblasts and vascular smooth muscle cells
    • Eickelberg O, Roth M, Lörx R, Bruce V, Rüdiger J, Johnson M, Block LH. Ligand-independent activation of the glucocorticoid receptor by ß2-adrenergic receptor agonists in primary human lung fi broblasts and vascular smooth muscle cells. J Biol Chem 1999; 274: 1005-1010.
    • (1999) J Biol Chem , vol.274 , pp. 1005-1010
    • Eickelberg, O.1    Roth, M.2    Lörx, R.3    Bruce, V.4    Rüdiger, J.5    Johnson, M.6    Block, L.H.7
  • 26
    • 0020639160 scopus 로고
    • Acute dose-response studies in bronchial asthma with a new corticosteroid, budesonide
    • Ellul-Micallef R, Johansson SÅ. Acute dose-response studies in bronchial asthma with a new corticosteroid, budesonide. Brit J Clin Pharmacol 1983; 15: 419-422.
    • (1983) Brit J Clin Pharmacol , vol.15 , pp. 419-422
    • Ellul-Micallef, R.1    Johansson, S.Å.2
  • 27
    • 3142517969 scopus 로고    scopus 로고
    • Canadian Asthma Exacerbation Study Group. Doubling the dose of budesonide versus maintenance treatment in asthma exacerbations
    • FitzGerald JM, Becker A, Sears MR, Mink S, Chung K, Lee J, Canadian Asthma Exacerbation Study Group. Doubling the dose of budesonide versus maintenance treatment in asthma exacerbations. Thorax 2004a; 59: 550-556.
    • (2004) Thorax , vol.59 , pp. 550-556
    • FitzGerald, J.M.1    Becker, A.2    Sears, M.R.3    Mink, S.4    Chung, K.5    Lee, J.6
  • 28
    • 33751242561 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/formoterol in a single inhaler-effi cacy and safety
    • FitzGerald JM, Olsson P, Michils A. Adjustable maintenance dosing with budesonide/formoterol in a single inhaler-effi cacy and safety. Int J Clin Pract 2004b; 58: 18-25.
    • (2004) Int J Clin Pract , vol.58 , pp. 18-25
    • FitzGerald, J.M.1    Olsson, P.2    Michils, A.3
  • 29
    • 10744229972 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fi xed dosing: a fi ve-month multicentre Canadian study
    • FitzGerald JM, Sears MR, Boulet L-P, Becker AB et al. Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fi xed dosing: a fi ve-month multicentre Canadian study. Can Respir J 2003; 10: 427-434.
    • (2003) Can Respir J , vol.10 , pp. 427-434
    • FitzGerald, J.M.1    Sears, M.R.2    Boulet, L.-P.3    Becker, A.B.4
  • 30
    • 0033998016 scopus 로고    scopus 로고
    • Low-dose budesonide with the addition of an increased dose during exacerbations is effective in long-term asthma control
    • Foresi A, Morelli MC, Catena E. Low-dose budesonide with the addition of an increased dose during exacerbations is effective in long-term asthma control. Chest 2000; 117: 400-406.
    • (2000) Chest , vol.117 , pp. 400-406
    • Foresi, A.1    Morelli, M.C.2    Catena, E.3
  • 31
    • 33745714436 scopus 로고    scopus 로고
    • Downregulation by a long-acting ß2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial infl ammatory mediator production
    • Fragaki K, Kileztky C, Trentesaux C, Zahm JM, Bajolet O, Johnson M, Puchelle E. Downregulation by a long-acting ß2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial infl ammatory mediator production. Am J Physiol Lung Cell Mol Physiol 2006; 291: L11-18.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Fragaki, K.1    Kileztky, C.2    Trentesaux, C.3    Zahm, J.M.4    Bajolet, O.5    Johnson, M.6    Puchelle, E.7
  • 32
    • 14744288245 scopus 로고    scopus 로고
    • Teaching old drugs new tricks: asthma therapy adjusted by patient perception or noninvasive markers
    • Gibson PG. Teaching old drugs new tricks: asthma therapy adjusted by patient perception or noninvasive markers. Eur Respir J 2005; 25: 397-399.
    • (2005) Eur Respir J , vol.25 , pp. 397-399
    • Gibson, P.G.1
  • 33
    • 33644874322 scopus 로고    scopus 로고
    • Long-acting beta2-agonists as an inhaled corticosteroidsparing agent for chronic asthma in adults and children
    • Gibson PG, Powell H, Ducharme F. Long-acting beta2-agonists as an inhaled corticosteroidsparing agent for chronic asthma in adults and children. Cochrane Database Systematic Review 2005; 4: CD005076.
    • (2005) Cochrane Database Systematic Review , vol.4
    • Gibson, P.G.1    Powell, H.2    Ducharme, F.3
  • 34
    • 84890680010 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. Publication no. NIH-NHLI 02-3569. Bethesda, MD: National Institutes of Health 2002.
    • Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. Publication no. NIH-NHLI 02-3569. Bethesda, MD: National Institutes of Health 2002.
  • 35
    • 33750685972 scopus 로고    scopus 로고
    • Comparison of asthma treatment given in addition to inhaled corticosteroids on airway infl ammation and responsiveness
    • Green RH, Brightling CE, McKenna S, Hargadon B et al. Comparison of asthma treatment given in addition to inhaled corticosteroids on airway infl ammation and responsiveness. Eur Respir J 2006; 27: 1144-1151.
    • (2006) Eur Respir J , vol.27 , pp. 1144-1151
    • Green, R.H.1    Brightling, C.E.2    McKenna, S.3    Hargadon, B.4
  • 36
    • 0028264310 scopus 로고
    • Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled steroid
    • Greening AP, Ind PW, Northfield M, Shaw G. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled steroid. Lancet 1994; 344: 219-224.
    • (1994) Lancet , vol.344 , pp. 219-224
    • Greening, A.P.1    Ind, P.W.2    Northfield, M.3    Shaw, G.4
  • 37
    • 0030976597 scopus 로고    scopus 로고
    • Effects of two weeks of topical budesonide treatment on microvascular exudative responsiveness in healthy human nasal airways
    • Greiff L, Andersson M, Svensson C, Akerlund A, Alkner U, Persson CG. Effects of two weeks of topical budesonide treatment on microvascular exudative responsiveness in healthy human nasal airways. Eur Respir J 1997; 10: 841-845.
    • (1997) Eur Respir J , vol.10 , pp. 841-845
    • Greiff, L.1    Andersson, M.2    Svensson, C.3    Akerlund, A.4    Alkner, U.5    Persson, C.G.6
  • 38
    • 0031701119 scopus 로고    scopus 로고
    • Effects of formoterol on histamine induced plasma exudation in induced sputum from normal subjects
    • Greiff L, Wollmer P, Andersson M, Svensson C, Persson CGA. Effects of formoterol on histamine induced plasma exudation in induced sputum from normal subjects. Thorax 1998; 53, 1010-1013.
    • (1998) Thorax , vol.53 , pp. 1010-1013
    • Greiff, L.1    Wollmer, P.2    Andersson, M.3    Svensson, C.4    Persson, C.G.A.5
  • 39
    • 0942278956 scopus 로고    scopus 로고
    • Doubling the dose of inhaled corticosteroid to prevent asthma exacerbations: randomised controlled trial
    • Harrison TW, Oborne J, Newton S, Tattersfield AE. Doubling the dose of inhaled corticosteroid to prevent asthma exacerbations: randomised controlled trial. Lancet 2004; 363: 271-275.
    • (2004) Lancet , vol.363 , pp. 271-275
    • Harrison, T.W.1    Oborne, J.2    Newton, S.3    Tattersfield, A.E.4
  • 40
    • 34250005443 scopus 로고    scopus 로고
    • Addition of salmeterol to fl uticasone prolongs retention of glucocorticoid receptors within the nucleus of BEAS-2B cells and enhances downstream glucocorticoid effects
    • Haque RA, Johnson M, Adcock IM, Barnes PJ. Addition of salmeterol to fl uticasone prolongs retention of glucocorticoid receptors within the nucleus of BEAS-2B cells and enhances downstream glucocorticoid effects. Proc Am Thorac Soc 2006; 3: A78.
    • (2006) Proc Am Thorac Soc , vol.3
    • Haque, R.A.1    Johnson, M.2    Adcock, I.M.3    Barnes, P.J.4
  • 41
    • 33745746529 scopus 로고    scopus 로고
    • Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma
    • Hew M, Bhavsar P, Torrego A, Meah S et al. Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma. Am J Respir Crit Care Med 2006; 174: 134-141.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 134-141
    • Hew, M.1    Bhavsar, P.2    Torrego, A.3    Meah, S.4
  • 42
  • 43
    • 2342625407 scopus 로고    scopus 로고
    • Adjustable and fi xed dosing with budesonide/ formoterol via a single inhaler in asthma patients: the ASSURE study
    • Ind PW, Haughney J, Price D, Rosen J-P, Kennelly J. Adjustable and fi xed dosing with budesonide/ formoterol via a single inhaler in asthma patients: the ASSURE study. Respir Med 2004; 98: 464-475.
    • (2004) Respir Med , vol.98 , pp. 464-475
    • Ind, P.W.1    Haughney, J.2    Price, D.3    Rosen, J.-P.4    Kennelly, J.5
  • 44
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-?B suppression
    • Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcock IM. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-?B suppression. J Exp Med 2006; 203: 7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 45
    • 33745356774 scopus 로고    scopus 로고
    • Control of airway infl ammation maintained at a lower steroid dose with 100/50 μg of fl uticasone propionate/salmeterol
    • Jarjour NN, Wilson SJ, Koenig SM, Laviolette M et al. Control of airway infl ammation maintained at a lower steroid dose with 100/50 μg of fl uticasone propionate/salmeterol. J Allergy Clin Immunol 2006; 118: 44-52.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 44-52
    • Jarjour, N.N.1    Wilson, S.J.2    Koenig, S.M.3    Laviolette, M.4
  • 46
    • 84889282518 scopus 로고    scopus 로고
    • Effect of budesonide and formoterol on glucocorticoid receptor DNA binding and transactivation in BEAS-2B cells
    • Jazrawi E, Ito K, Barnes PJ, Adcock IM. Effect of budesonide and formoterol on glucocorticoid receptor DNA binding and transactivation in BEAS-2B cells Proc Am Thorac Soc 2005; 2: A108.
    • (2005) Proc Am Thorac Soc , vol.2
    • Jazrawi, E.1    Ito, K.2    Barnes, P.J.3    Adcock, I.M.4
  • 47
    • 18744362435 scopus 로고    scopus 로고
    • Effects of salmeterol on mucosal infl ammation in asthma: a placebo-controlled study
    • Jeffery PK, Venge P, Gizycki MJ, Egerod I, Dahl R, Faurschou P. Effects of salmeterol on mucosal infl ammation in asthma: a placebo-controlled study. Eur Respir J 2002; 20: 1378-1385.
    • (2002) Eur Respir J , vol.20 , pp. 1378-1385
    • Jeffery, P.K.1    Venge, P.2    Gizycki, M.J.3    Egerod, I.4    Dahl, R.5    Faurschou, P.6
  • 48
    • 0035042689 scopus 로고    scopus 로고
    • Pharmacokinetics of budesonide and its major ester metabolite after inhalation and intravenous administration of budesonide in the rat
    • Jendbro M, Johansson CJ, Strandberg P, Falk-Nilsson H, Edsbäcker S. Pharmacokinetics of budesonide and its major ester metabolite after inhalation and intravenous administration of budesonide in the rat. Drug Metab Dispos 2001; 29: 769-776.
    • (2001) Drug Metab Dispos , vol.29 , pp. 769-776
    • Jendbro, M.1    Johansson, C.J.2    Strandberg, P.3    Falk-Nilsson, H.4    Edsbäcker, S.5
  • 49
    • 0033910893 scopus 로고    scopus 로고
    • Salmeterol/fl uticasone propionate combination therapy 50/250 μg bid is more effective than budesonide 800 μg bid in treating moderate-to-severe asthma
    • Jenkins C, Woolcock AJ, Saarelainen P, Lundbäck B, James MH. Salmeterol/fl uticasone propionate combination therapy 50/250 μg bid is more effective than budesonide 800 μg bid in treating moderate-to-severe asthma. Respir Med 2000; 94: 715-723.
    • (2000) Respir Med , vol.94 , pp. 715-723
    • Jenkins, C.1    Woolcock, A.J.2    Saarelainen, P.3    Lundbäck, B.4    James, M.H.5
  • 50
    • 0034784038 scopus 로고    scopus 로고
    • Comparison of salmeterol/ fl uticasone propionate combination with budesonide in patients with mild-to-moderate asthma
    • Johansson G, McIvor RA, Purello D'Ambrosio F, Gratziou C, James MH. Comparison of salmeterol/ fl uticasone propionate combination with budesonide in patients with mild-to-moderate asthma. Clin Drug Invest 2001; 21: 633-642.
    • (2001) Clin Drug Invest , vol.21 , pp. 633-642
    • Johansson, G.1    McIvor, R.A.2    Purello D'Ambrosio, F.3    Gratziou, C.4    James, M.H.5
  • 51
    • 84890734440 scopus 로고    scopus 로고
    • Long-acting ß2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airways epithelial and smooth muscle cells
    • [Epub ahead of print]
    • Kaur M, Chivers JE, Giembycz MA, Newton R. Long-acting ß2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airways epithelial and smooth muscle cells. Mol Pharmacol 2007; [Epub ahead of print]
    • (2007) Mol Pharmacol
    • Kaur, M.1    Chivers, J.E.2    Giembycz, M.A.3    Newton, R.4
  • 52
    • 0034105388 scopus 로고    scopus 로고
    • A long-term study of the antiinfl ammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma
    • Kips JC, O'Connor J, Inman MD, Svensson K, Pauwels RA, O'Byrne PM. A long-term study of the antiinfl ammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma. Am J Respir Crit Care Med 2000; 161: 996-1001.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 996-1001
    • Kips, J.C.1    O'Connor, J.2    Inman, M.D.3    Svensson, K.4    Pauwels, R.A.5    O'Byrne, P.M.6
  • 53
    • 33645564704 scopus 로고    scopus 로고
    • Adding salmeterol to an inhaled corticosteroid: long term effects on bronchial infl ammation in asthma
    • Koopmans JG, Lutter R, Jansen HM, van der Zee JS. Adding salmeterol to an inhaled corticosteroid: long term effects on bronchial infl ammation in asthma. Thorax 2006; 61: 306-312.
    • (2006) Thorax , vol.61 , pp. 306-312
    • Koopmans, J.G.1    Lutter, R.2    Jansen, H.M.3    van der Zee, J.S.4
  • 54
    • 0034901163 scopus 로고    scopus 로고
    • Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells
    • Korn SH, Jerre A, Brattsand R. Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells. Eur Respir J 2001; 17: 1070-1077.
    • (2001) Eur Respir J , vol.17 , pp. 1070-1077
    • Korn, S.H.1    Jerre, A.2    Brattsand, R.3
  • 55
    • 0038216589 scopus 로고    scopus 로고
    • Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma
    • Lalloo UG, Malolepszy J, Kozma D, Krofta K, Ankerst J, Johansen B, Thomson NC. Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma. Chest 2003; 123: 1480-1487.
    • (2003) Chest , vol.123 , pp. 1480-1487
    • Lalloo, U.G.1    Malolepszy, J.2    Kozma, D.3    Krofta, K.4    Ankerst, J.5    Johansen, B.6    Thomson, N.C.7
  • 56
    • 0342419450 scopus 로고    scopus 로고
    • Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol
    • Lemanske RF, Sorkness CA, Mauger EA, Lazarus SC et al. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol. J Amer Med Assoc 2001; 285: 2594-2603.
    • (2001) J Amer Med Assoc , vol.285 , pp. 2594-2603
    • Lemanske, R.F.1    Sorkness, C.A.2    Mauger, E.A.3    Lazarus, S.C.4
  • 57
    • 0142194042 scopus 로고    scopus 로고
    • Glucocorticoid receptor activation by steroids and long-acting ß2-agonists in vivo: A double-blind crossover study
    • Leufgen H, Rüdiger JJ, Herrmann MJ, Meyer L et al. Glucocorticoid receptor activation by steroids and long-acting ß2-agonists in vivo: A double-blind crossover study. Am J Respir Crit Care Med 2002; 165: A618.
    • (2002) Am J Respir Crit Care Med , vol.165
    • Leufgen, H.1    Rüdiger, J.J.2    Herrmann, M.J.3    Meyer, L.4
  • 58
    • 0037248247 scopus 로고    scopus 로고
    • Update on glucocorticoid action and resistance
    • Leung DY, Bloom JW. Update on glucocorticoid action and resistance. J Allergy Clin Immunol 2003; 111: 3-22.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 3-22
    • Leung, D.Y.1    Bloom, J.W.2
  • 59
    • 0041366026 scopus 로고    scopus 로고
    • An individualized, adjustable maintenance regimen of budesonide/formoterol provides effective asthma symptom control at a lower overall dose than fi xed dosing
    • Leuppi JD, Salzberg M, Meyer L, Bucher SE, Nief M, Brutsche MH, Tamm M. An individualized, adjustable maintenance regimen of budesonide/formoterol provides effective asthma symptom control at a lower overall dose than fi xed dosing. Swiss Med Wkly 2003; 133: 302-309.
    • (2003) Swiss Med Wkly , vol.133 , pp. 302-309
    • Leuppi, J.D.1    Salzberg, M.2    Meyer, L.3    Bucher, S.E.4    Nief, M.5    Brutsche, M.H.6    Tamm, M.7
  • 60
    • 0032724631 scopus 로고    scopus 로고
    • An antiinfl ammatory effect of salmeterol, a long-acting ß2 agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma
    • Li X, Ward C, Thien F, Bish R et al. An antiinfl ammatory effect of salmeterol, a long-acting ß2 agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma. Am J Respir Crit Care Med 1999; 160: 1493-1499.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1493-1499
    • Li, X.1    Ward, C.2    Thien, F.3    Bish, R.4
  • 62
    • 38849123625 scopus 로고    scopus 로고
    • Anti-infl ammatory activity of ß2-agonists in primary lung epithelial cells is independent of glucocorticoid receptor
    • Lovén J, Svitacheva N, Jerre A, Miller-Larsson A, Korn SH. Anti-infl ammatory activity of ß2-agonists in primary lung epithelial cells is independent of glucocorticoid receptor. Eur Respir J 2007; 30: 848-856.
    • (2007) Eur Respir J , vol.30 , pp. 848-856
    • Lovén, J.1    Svitacheva, N.2    Jerre, A.3    Miller-Larsson, A.4    Korn, S.H.5
  • 64
    • 2342567291 scopus 로고    scopus 로고
    • Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
    • Matthews JG, Ito K, Barnes PJ, Adcock IM. Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J Allergy Clin Immunol 2004; 113: 1100-1108.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 1100-1108
    • Matthews, J.G.1    Ito, K.2    Barnes, P.J.3    Adcock, I.M.4
  • 68
    • 0031846019 scopus 로고    scopus 로고
    • Reversible fatty acid conjugation of budesonide. Novel mechanism for prolonged retention of topically applied steroid in airway tissue
    • Miller-Larsson A, Mattsson H, Hjertberg E, Dahlbäck M, Tunek A, Brattsand R. Reversible fatty acid conjugation of budesonide. Novel mechanism for prolonged retention of topically applied steroid in airway tissue. Drug Metab Dispos 1998; 26: 623-630
    • (1998) Drug Metab Dispos , vol.26 , pp. 623-630
    • Miller-Larsson, A.1    Mattsson, H.2    Hjertberg, E.3    Dahlbäck, M.4    Tunek, A.5    Brattsand, R.6
  • 69
    • 11144355937 scopus 로고    scopus 로고
    • Additive blockade of ß2-integrin adhesion of eosinophils by salmeterol and fl uticasone propionate
    • Myo S, Zhu X, Myou S, Meliton AY et al. Additive blockade of ß2-integrin adhesion of eosinophils by salmeterol and fl uticasone propionate. Eur Respir J 2004; 23: 511-517.
    • (2004) Eur Respir J , vol.23 , pp. 511-517
    • Myo, S.1    Zhu, X.2    Myou, S.3    Meliton, A.Y.4
  • 70
    • 21244495174 scopus 로고    scopus 로고
    • ß2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation
    • Nie M, Knox AJ, Pang L. ß2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation. J Immunol 2005; 175: 478-86.
    • (2005) J Immunol , vol.175 , pp. 478-86
    • Nie, M.1    Knox, A.J.2    Pang, L.3
  • 71
    • 0033451025 scopus 로고    scopus 로고
    • Salmeterol reduces the need for inhaled corticosteroids in steroid-dependent asthmatics
    • Nielsen LP, Pedersen B, Faurschou P, Madsen F, Wilcke JTR, Dahl R. Salmeterol reduces the need for inhaled corticosteroids in steroid-dependent asthmatics. Respir Med 1999; 93: 863-868.
    • (1999) Respir Med , vol.93 , pp. 863-868
    • Nielsen, L.P.1    Pedersen, B.2    Faurschou, P.3    Madsen, F.4    Wilcke, J.T.R.5    Dahl, R.6
  • 72
    • 0031896352 scopus 로고    scopus 로고
    • Beta-adrenoceptor agonists block corticosteroid inhibition in eosinophils
    • Nielson CP, Hadjokas NE. Beta-adrenoceptor agonists block corticosteroid inhibition in eosinophils. Am J Respir Crit Care Med 1998; 157: 184-191.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 184-191
    • Nielson, C.P.1    Hadjokas, N.E.2
  • 73
    • 0345874610 scopus 로고    scopus 로고
    • Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model
    • Norman AW, Mizwicki MT, Norman DP. Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model. Nat Rev Drug Discov 2004; 3: 27-41.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 27-41
    • Norman, A.W.1    Mizwicki, M.T.2    Norman, D.P.3
  • 75
    • 12144270425 scopus 로고    scopus 로고
    • Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma
    • O'Byrne PM, Bisgaard H, Godard PP, Pistolesi M et al. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med 2005; 171: 129-136.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 129-136
    • O'Byrne, P.M.1    Bisgaard, H.2    Godard, P.P.3    Pistolesi, M.4
  • 76
    • 0031838170 scopus 로고    scopus 로고
    • Salmeterol enhances the inhibitory activity of dexamethasone on allergen-induced blood mononuclear cell activation
    • Oddera S, Silvestri M, Testi R, Rossi GA. Salmeterol enhances the inhibitory activity of dexamethasone on allergen-induced blood mononuclear cell activation. Respiration 1998; 65: 199-204.
    • (1998) Respiration , vol.65 , pp. 199-204
    • Oddera, S.1    Silvestri, M.2    Testi, R.3    Rossi, G.A.4
  • 78
    • 24944501227 scopus 로고    scopus 로고
    • Formoterol added to lowdose budesonide has no additional antiinfl ammatory effect in asthmatic patients
    • Overbeek SE, Mulder PG, Baelemans SM, Hoogsteden HC, Prins JB. Formoterol added to lowdose budesonide has no additional antiinfl ammatory effect in asthmatic patients. Chest 2005; 128: 1121-1127.
    • (2005) Chest , vol.128 , pp. 1121-1127
    • Overbeek, S.E.1    Mulder, P.G.2    Baelemans, S.M.3    Hoogsteden, H.C.4    Prins, J.B.5
  • 79
    • 7944233169 scopus 로고    scopus 로고
    • Synergistic effects of fl uticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma
    • Pace E, Gagliardo R, Melis M, La Grutta S et al. Synergistic effects of fl uticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma. J Allergy Clin Immunol 2004; 114: 1216-1223.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1216-1223
    • Pace, E.1    Gagliardo, R.2    Melis, M.3    La Grutta, S.4
  • 80
    • 0028277771 scopus 로고
    • Postallergen inhaled budesonide reduces late asthmatic response and inhibits the associated increase of airway responsiveness to methacholine in asthmatics
    • Paggiaro PL, Dente FL, Morelli MC, Bancalari L et al. Postallergen inhaled budesonide reduces late asthmatic response and inhibits the associated increase of airway responsiveness to methacholine in asthmatics. Am J Respir Crit Care Med 1994; 149: 1447-1451.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 1447-1451
    • Paggiaro, P.L.1    Dente, F.L.2    Morelli, M.C.3    Bancalari, L.4
  • 81
    • 0032793507 scopus 로고    scopus 로고
    • Comparison of the relative effi cacy of formoterol and salmeterol in asthmatic patients
    • Palmqvist M, Ibsen T, Mellén A, Lötvall J. Comparison of the relative effi cacy of formoterol and salmeterol in asthmatic patients. Am J Respir Crit Care Med 1999; 160: 244-249.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 244-249
    • Palmqvist, M.1    Ibsen, T.2    Mellén, A.3    Lötvall, J.4
  • 82
    • 0033899452 scopus 로고    scopus 로고
    • Synergistic inhibition by ß2-agonists and corticosteroids on tumor necrosis factor-a-induced interleukin-8 release from cultured human airway smooth-muscle cells
    • Pang L, Knox AJ. Synergistic inhibition by ß2-agonists and corticosteroids on tumor necrosis factor-a-induced interleukin-8 release from cultured human airway smooth-muscle cells. Am J Respir Cell Mol Biol 2000; 23: 79-85.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , pp. 79-85
    • Pang, L.1    Knox, A.J.2
  • 83
    • 0035148088 scopus 로고    scopus 로고
    • Regulation of TNF-a-induced eotaxin release from cultured human airway smooth muscle cells by ß2-agonists and corticosteroids
    • Pang L, Knox AJ. Regulation of TNF-a-induced eotaxin release from cultured human airway smooth muscle cells by ß2-agonists and corticosteroids. FASEB J 2001; 15: 261-269.
    • (2001) FASEB J , vol.15 , pp. 261-269
    • Pang, L.1    Knox, A.J.2
  • 84
    • 0033833679 scopus 로고    scopus 로고
    • Protective effects of fl uticasone on allergen-induced airway responses and sputum infl ammatory markers
    • Parameswaran K, Inman MD, Watson RM, Morris MM et al. Protective effects of fl uticasone on allergen-induced airway responses and sputum infl ammatory markers. Can Respir J 2000; 7: 313-319.
    • (2000) Can Respir J , vol.7 , pp. 313-319
    • Parameswaran, K.1    Inman, M.D.2    Watson, R.M.3    Morris, M.M.4
  • 87
    • 14344264164 scopus 로고    scopus 로고
    • Biochemical interaction between effects of beclomethasone dipropionate and salbutamol or formoterol in sputum cells from mild to moderate asthmatics
    • Profita M, Gagliardo R, Di Giorgi R, Pompeo F et al. Biochemical interaction between effects of beclomethasone dipropionate and salbutamol or formoterol in sputum cells from mild to moderate asthmatics. Allergy 2005; 60: 323-329.
    • (2005) Allergy , vol.60 , pp. 323-329
    • Profita, M.1    Gagliardo, R.2    Di Giorgi, R.3    Pompeo, F.4
  • 88
    • 33344471388 scopus 로고    scopus 로고
    • Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma
    • Rabe KF, Pizzichini E, Ställberg B, Romero S et al. Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma. A randomized, double-blind trial. Chest 2006; 129: 246-256.
    • (2006) A randomized, double-blind trial. Chest , vol.129 , pp. 246-256
    • Rabe, K.F.1    Pizzichini, E.2    Ställberg, B.3    Romero, S.4
  • 89
    • 0037975664 scopus 로고    scopus 로고
    • Possible anti-infl ammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo
    • Reid DW, Ward C, Wang N, Zheng L, Bish R, Orsida B, Walters EH. Possible anti-infl ammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo. Eur Respir J 2003; 21: 994-999.
    • (2003) Eur Respir J , vol.21 , pp. 994-999
    • Reid, D.W.1    Ward, C.2    Wang, N.3    Zheng, L.4    Bish, R.5    Orsida, B.6    Walters, E.H.7
  • 90
    • 0031667891 scopus 로고    scopus 로고
    • Onset and duration of action of single doses of formoterol inhaled via Turbuhaler
    • Ringdal N, Derom E, Wåhlin-Boll E, Pauwels R. Onset and duration of action of single doses of formoterol inhaled via Turbuhaler. Respir Med 1998; 92: 1017-1021.
    • (1998) Respir Med , vol.92 , pp. 1017-1021
    • Ringdal, N.1    Derom, E.2    Wåhlin-Boll, E.3    Pauwels, R.4
  • 91
    • 0037180086 scopus 로고    scopus 로고
    • Interaction between glucocorticoids and ß2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
    • Roth M, Johnson PRA, Rüdiger JJ, King GG et al. Interaction between glucocorticoids and ß2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet 2002; 360: 1293-1299.
    • (2002) Lancet , vol.360 , pp. 1293-1299
    • Roth, M.1    Johnson, P.R.A.2    Rüdiger, J.J.3    King, G.G.4
  • 92
    • 5444248773 scopus 로고    scopus 로고
    • Effi cacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma
    • Scicchitano R, Aalbers R, Ukena D, Manjra A et al. Effi cacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma. Curr Med Res Opin 2004; 20: 1403-1418.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1403-1418
    • Scicchitano, R.1    Aalbers, R.2    Ukena, D.3    Manjra, A.4
  • 93
    • 0033623853 scopus 로고    scopus 로고
    • Oxis (formoterol given by Turbuhaler) showed as rapid an onset of action as salbutamol given by a pMDI
    • Seberová E, Andersson A. Oxis (formoterol given by Turbuhaler) showed as rapid an onset of action as salbutamol given by a pMDI. Respir Med 2000; 94: 607-611.
    • (2000) Respir Med , vol.94 , pp. 607-611
    • Seberová, E.1    Andersson, A.2
  • 94
    • 0031755222 scopus 로고    scopus 로고
    • Does salmeterol facilitate "step-down" therapy in patients with asthma receiving moderate to high doses of inhaled corticosteroids?
    • Self T, Rumbak MJ, Kelso T, Eberle L et al. Does salmeterol facilitate "step-down" therapy in patients with asthma receiving moderate to high doses of inhaled corticosteroids? Curr Ther Res 1998; 59: 803-811.
    • (1998) Curr Ther Res , vol.59 , pp. 803-811
    • Self, T.1    Rumbak, M.J.2    Kelso, T.3    Eberle, L.4
  • 95
    • 0034900615 scopus 로고    scopus 로고
    • Fluticasone and salmeterol downregulate in vitro, fi broblast proliferation and ICAM-1 or H-CAM expression
    • Silvestri M, Fregonese L, Sabatini F, Dasic G, Rossi GA. Fluticasone and salmeterol downregulate in vitro, fi broblast proliferation and ICAM-1 or H-CAM expression. Eur Respir J 2001; 18: 139-145.
    • (2001) Eur Respir J , vol.18 , pp. 139-145
    • Silvestri, M.1    Fregonese, L.2    Sabatini, F.3    Dasic, G.4    Rossi, G.A.5
  • 96
    • 3142655932 scopus 로고    scopus 로고
    • Pharmacological management to reduce exacerbations in adults with asthma: A systematic review and meta-analysis
    • Sin DD, Man J, Sharpe H, Gan WQ, Man SFP. Pharmacological management to reduce exacerbations in adults with asthma: A systematic review and meta-analysis. J Am Med Assoc 2004; 292: 367-376.
    • (2004) J Am Med Assoc , vol.292 , pp. 367-376
    • Sin, D.D.1    Man, J.2    Sharpe, H.3    Gan, W.Q.4    Man, S.F.P.5
  • 97
    • 0036191465 scopus 로고    scopus 로고
    • Additive anti-infl ammatory effect of formoterol and budesonide on human lung fi broblasts
    • Spoelstra FM, Postma DS, Hovenga H, Noordhoek JA, Kauffman HF. Additive anti-infl ammatory effect of formoterol and budesonide on human lung fi broblasts. Thorax 2002; 57: 237-241.
    • (2002) Thorax , vol.57 , pp. 237-241
    • Spoelstra, F.M.1    Postma, D.S.2    Hovenga, H.3    Noordhoek, J.A.4    Kauffman, H.F.5
  • 98
    • 0242575119 scopus 로고    scopus 로고
    • Budesonide/formoterol adjustable maintenance dosing reduces asthma exacerbations versus fi xed dosing
    • Ställberg B, Olsson P, Jörgensen LA, Lindarck N, Ekström T. Budesonide/formoterol adjustable maintenance dosing reduces asthma exacerbations versus fi xed dosing. Int J Clin Pract 2003; 57: 656-661.
    • (2003) Int J Clin Pract , vol.57 , pp. 656-661
    • Ställberg, B.1    Olsson, P.2    Jörgensen, L.A.3    Lindarck, N.4    Ekström, T.5
  • 99
  • 100
    • 0037246566 scopus 로고    scopus 로고
    • Effi cacy and safety of budesonide/formoterol in the management of obstructive pulmonary disease
    • Szafranski W, Cukier A, Ramirez A, Menga G et al. Effi cacy and safety of budesonide/formoterol in the management of obstructive pulmonary disease. Eur Respir J 2003; 21: 74-81.
    • (2003) Eur Respir J , vol.21 , pp. 74-81
    • Szafranski, W.1    Cukier, A.2    Ramirez, A.3    Menga, G.4
  • 102
    • 0033998927 scopus 로고    scopus 로고
    • Comparison of the effects of selective and non-selective beta-adrenoreceptor agonists on the pro-infl ammatory activities of human neutrophils in vitro
    • Tintinger GR, Anderson R, Theron AJ, Ramafi G, Ker JA. Comparison of the effects of selective and non-selective beta-adrenoreceptor agonists on the pro-infl ammatory activities of human neutrophils in vitro. Infl ammation 2000; 24: 239-249.
    • (2000) Infl ammation , vol.24 , pp. 239-249
    • Tintinger, G.R.1    Anderson, R.2    Theron, A.J.3    Ramafi, G.4    Ker, J.A.5
  • 103
    • 84890738019 scopus 로고    scopus 로고
    • Formoterol restores corticosteroid responses in corticosteroid-insensitive
    • To Y, Ito M, Adcock IM, Barnes PJ, Ito K. Formoterol restores corticosteroid responses in corticosteroid-insensitive asthma. Eur Respir J 2005a; 26: 50s
    • (2005) Eur Respir J , vol.26 , pp. 50
    • To, Y.1    Ito, M.2    Adcock, I.M.3    Barnes, P.J.4    Ito, K.5
  • 104
    • 84890707168 scopus 로고    scopus 로고
    • Salmeterol treatment improves corticosteroid responsiveness in patients with corticosteroid-insensitive severe
    • To Y, Adcock IM, Barnes PJ, Ito K. Salmeterol treatment improves corticosteroid responsiveness in patients with corticosteroid-insensitive severe asthma Eur Respir J 2005b; 26: 465s.
    • (2005) Asthma Eur Respir J , vol.26 , pp. 465
    • To, Y.1    Adcock, I.M.2    Barnes, P.J.3    Ito, K.4
  • 106
    • 84890661547 scopus 로고    scopus 로고
    • Inhibitory effects of fudesonide and formoterol in combination on TGFß-induced proteoglycan production by bronchial biopsy fi broblasts from healthy and mild asthmatic subjects
    • Todorova L, Bjermer L, Miller-Larsson A, Westergren-Thorsson G. Inhibitory effects of fudesonide and formoterol in combination on TGFß-induced proteoglycan production by bronchial biopsy fi broblasts from healthy and mild asthmatic subjects. Eur Respir J 2007; 30: 352
    • (2007) Eur Respir J , vol.30 , pp. 352
    • Todorova, L.1    Bjermer, L.2    Miller-Larsson, A.3    Westergren-Thorsson, G.4
  • 107
    • 0019986101 scopus 로고
    • Influence of dosing frequency and schedule on the response of chronic asthmatics to the aerosol steroid, budesonide
    • Toogood JH, Baskerville JC, Jennings B, Lefcoe NM, Johansson SA. Influence of dosing frequency and schedule on the response of chronic asthmatics to the aerosol steroid, budesonide. J Allergy Clin Immunol 1982; 70: 288-298.
    • (1982) J Allergy Clin Immunol , vol.70 , pp. 288-298
    • Toogood, J.H.1    Baskerville, J.C.2    Jennings, B.3    Lefcoe, N.M.4    Johansson, S.A.5
  • 108
    • 0023762749 scopus 로고
    • Salmeterol, a new long acting inhaled beta2adrenoceptor agonist: comparison with salbutamol in adult asthmatic patients
    • Ullman A, Svedmyr N. Salmeterol, a new long acting inhaled beta2adrenoceptor agonist: comparison with salbutamol in adult asthmatic patients. Thorax 1988; 43: 674-678.
    • (1988) Thorax , vol.43 , pp. 674-678
    • Ullman, A.1    Svedmyr, N.2
  • 110
    • 0037108635 scopus 로고    scopus 로고
    • Effect of combining salmeterol and fl uticasone on the progression of airway remodeling
    • Vanacker NJ, Palmans E, Pauwels RA, Kips JC. Effect of combining salmeterol and fl uticasone on the progression of airway remodeling. Am J Respir Crit Care Med 2002; 166: 1128-1134.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1128-1134
    • Vanacker, N.J.1    Palmans, E.2    Pauwels, R.A.3    Kips, J.C.4
  • 111
    • 27744557795 scopus 로고    scopus 로고
    • Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option?
    • Vogelmeier C, D'Urzo A, Pauwels R, Merino JM et al. Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? Eur Respir J 2005; 26: 819-828.
    • (2005) Eur Respir J , vol.26 , pp. 819-828
    • Vogelmeier, C.1    D'Urzo, A.2    Pauwels, R.3    Merino, J.M.4
  • 112
    • 33749338671 scopus 로고    scopus 로고
    • Synergistic effects of fl uticasone propionate and salmeterol on inhibiting rhinovirus-induced epithelial production of remodelling-associated growth factors
    • Volonaki E, Psarras S, Xepapadaki P, Psomali D, Gourgiotis D, Papadopoulos NG. Synergistic effects of fl uticasone propionate and salmeterol on inhibiting rhinovirus-induced epithelial production of remodelling-associated growth factors. Clin Exp Allergy 2006; 36: 1268-1273.
    • (2006) Clin Exp Allergy , vol.36 , pp. 1268-1273
    • Volonaki, E.1    Psarras, S.2    Xepapadaki, P.3    Psomali, D.4    Gourgiotis, D.5    Papadopoulos, N.G.6
  • 114
    • 0036893330 scopus 로고    scopus 로고
    • The effects of regular inhaled formoterol and budesonide on preformed Th-2 cytokines in mild asthmatics
    • Wallin A, Sandström T, Cioppa GD, Holgate S, Wilson S. The effects of regular inhaled formoterol and budesonide on preformed Th-2 cytokines in mild asthmatics. Respir Med 2002; 96: 1021-1025.
    • (2002) Respir Med , vol.96 , pp. 1021-1025
    • Wallin, A.1    Sandström, T.2    Cioppa, G.D.3    Holgate, S.4    Wilson, S.5
  • 115
    • 0032924959 scopus 로고    scopus 로고
    • The effects of regular inhaled formoterol, budesonide, and placebo on mucosal infl ammation and clinical indices in mild asthma
    • Wallin A, Sandström T, Söderberg M, Howarth P et al. The effects of regular inhaled formoterol, budesonide, and placebo on mucosal infl ammation and clinical indices in mild asthma. Am J Respir Crit Care Med 1999; 159: 79-86.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 79-86
    • Wallin, A.1    Sandström, T.2    Söderberg, M.3    Howarth, P.4
  • 116
    • 0038681170 scopus 로고    scopus 로고
    • Effect of inhaled fl uticasone with and without salmeterol on airway infl ammation in asthma
    • Wallin A, Sue-Chu M, Bjermer L, Ward J et al. Effect of inhaled fl uticasone with and without salmeterol on airway infl ammation in asthma. J Allergy Clin Immunol 2003; 112: 72-78.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 72-78
    • Wallin, A.1    Sue-Chu, M.2    Bjermer, L.3    Ward, J.4
  • 117
    • 17144403499 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelial cells have a defi cient innate immune response to infection with rhinovirus
    • Wark PA, Johnston SL, Bucchieri F, Powell R et al. Asthmatic bronchial epithelial cells have a defi cient innate immune response to infection with rhinovirus. J Exp Med 2005; 201: 937-947.
    • (2005) J Exp Med , vol.201 , pp. 937-947
    • Wark, P.A.1    Johnston, S.L.2    Bucchieri, F.3    Powell, R.4
  • 118
    • 0030965337 scopus 로고    scopus 로고
    • Effect of long term treatment with salmeterol on asthma control: a double blind, randomised crossover study
    • Wilding P, Clark M, Thompson Coon J, Lewis S et al. Effect of long term treatment with salmeterol on asthma control: a double blind, randomised crossover study. BMJ 1997; 314: 1441-1446.
    • (1997) BMJ , vol.314 , pp. 1441-1446
    • Wilding, P.1    Clark, M.2    Thompson Coon, J.3    Lewis, S.4
  • 120
    • 0029880013 scopus 로고    scopus 로고
    • Comparison of the addition of salmeterol to inhaled steroids with doubling the dose of inhaled steroids
    • Woolcock A, Lundback B, Ringdal, Jacques LA. Comparison of the addition of salmeterol to inhaled steroids with doubling the dose of inhaled steroids. Am J Respir Crit Care Med 1996; 153: 1481-1488.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1481-1488
    • Woolcock, A.1    Lundback, B.2    Ringdal3    Jacques, L.A.4
  • 121
    • 33748538090 scopus 로고    scopus 로고
    • Formoterol-induced glucocorticoid receptor nuclear translocation in monocytes and U937 cells but not epithelial cell lines
    • Yanagawa H, Ito K, Barnes PJ, Adcock IM. Formoterol-induced glucocorticoid receptor nuclear translocation in monocytes and U937 cells but not epithelial cell lines. Am J Respir Crit Care Med 2001; 163: A734.
    • (2001) Am J Respir Crit Care Med , vol.163
    • Yanagawa, H.1    Ito, K.2    Barnes, P.J.3    Adcock, I.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.