Potential masking effects of salmeterol on airway inflammation in asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 158, Issue 3, 1998, Pages 924-930

  McIvor, R Andrew ^a   Pizzichini, Emilio ^a   Turner, Mark O ^a   Hussack, Patricia ^a   Hargreave, Frederick E ^a   Sears, Malcolm R ^a  

^a ST JOSEPH S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; SALMETEROL;

ADULT; ARTICLE; ASTHMA; BRONCHODILATATION; CONTROLLED STUDY; DISEASE COURSE; EOSINOPHILIA; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MASKING; PATHOGENESIS; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; PROVOCATION TEST; RESPIRATORY TRACT INFLAMMATION; SPIROMETRY; SPUTUM ANALYSIS;

EID: 0031750702     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.158.3.9802069     Document Type: Article

References (24)

1. Guidelines for the diagnosis and management of asthma. Expert panel report II. National Asthma Education and Prevention Program, April 1997. National Heart, Blood and Lung Institute, Bethesda, MD. NIH Publication No. 97-4051.
2. Greening, A. P., P. Wind, M. Northfield, and G. Shaw, on behalf of Allen & Hanburys Limited UK Study Group. 1994. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Lancet 344:219-224.
3. Woolcock, A., B. Lundback, N. Ringdal, and L. A. Jacques. 1996. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am. J. Respir. Crit. Care Med. 153:1481-1488.
4. Cumming, R. G., P. Mitchell, and S. R. Leeder. 1997. Use of inhaled corticosteroids and the risk of cataracts. N. Engl. J. Med. 337:8-14.
5. Kamada, A. K., S. J. Szefler, R. J. Martin, H. A. Boushey, V. M. Chinchilli, J. M. Drazen, J. E. Fish, E. Israel, S. C. Lazarus, and R. F. Lemanske. 1996. Issues in the use of inhaled glucocorticoids. Am. J. Respir. Crit. Care Med. 153:1739-1748.
6. Toogood, J. H. G., J. C. Baskerville, A. E. Markov, A. B. Hodsman, L. J. Fraher, B. Jennings, R. G. Haddad, and D. Drost. 1995. Bone mineral density and the risk of fracture in patients receiving long-term inhaled steroid therapy for asthma. J. Allergy Clin. Immunol. 96:157-166.
7. Arvidsson, P., S. Larsson, C.-G. Lofdahl, B. Melander, N. Svedmyr, and L. Wahlander. 1991. Inhaled formoterol during one year in asthma: a comparison with salbutamol. Eur. Respir. J. 4:1168-1173.
8. Pizzichini, E., M. M. M. Pizzichini, A. Efthimiadis, S. Evans, M. M. Morris, D. Squillace, G. J. Gleich, J. Dolovich, and F. E. Hargreave. 1996. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am. J. Respir. Crit. Care Med. 154:308-317.
9. Gibson, P. G., B. J. O. Wong, M. J. E. Hepperle, P. A. Kline, A. Girgis-Gabardo, G. Guyatt, J. Dolovich, J. A. Denburg, E. H. Ramsdale, and F. E. Hargreave. 1992. A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid. Clin. Exp. Allergy 22:525-532.
10. Marks, G. B., S. M. Dunn, and A. J. Woolcock. 1992. A scale for the measurement of quality of life in adults with asthma. J. Clin. Epidemiol. 45:461-472.
11. American Thoracic Society. 1995. Standardization of spirometry. Am. J. Respir. Crit. Care Med. 152:1107-1136.
12. Cockcroft, D. W., D. N. Killian, J. A. Mellon, and F. E. Hargreave. 1997. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin. Allergy 7:235-243.
13. Pepys, J. 1994. "Atopy": a study in definition. Allergy 49:397-399.
14. Pizzichini, E., M. M. M. Pizzichini, A. Efthimiadis, F. E. Hargreave, and J. Dolovich. 1996. Measurement of inflammatory indices in induced sputum: effects of selection of sputum to minimize salivary contamination. Eur. Respir. J. 9:1174-1180.
15. Pearlman, D. S., P. Chervinsky, C. LaForce, J. M. Seltzer, D. L. Southern, J. P. Kemp, R. J. Dockhorn, J. Grossman, R. F. Liddle, S. W. Yancey, D. M. Cocchetto, and W. J. Alexander. 1992. A comparison of salmeterol with albuterol in the treatment of mild to moderate asthma. N. Engl. J. Med. 327:1420-1425.
16. Leblanc, P., A. Knight, H. Kreisman, C. M. Borkhoff, and P. R. Johnston. 1996. A placebo-controlled, crossover comparison of salmeterol and salbutamol in patients with asthma. Am. J. Respir. Crit. Care Med. 154:324-328.
17. Boulet, L.-P., M. Laviolette, S. Boucher, A. Knight, J. Herbert, and K. R. Chapman. 1997. A twelve-week comparison of salmeterol and salbutamol in the treatment of mild to moderate asthma: a Canadian multicenter study. J. Allergy Clin. Immunol. 99:13-21.
18. Pizzichini, M. M. M., E. Pizzichini, I. Pavord, C. Lemiere, L. Clelland, A. Efthimiadis, S. Evans, J. Dolovich, and F. E. Hargreave. 1997. Sputum in prednisone dependent asthma (abstract). Am. J. Respir. Crit. Care Med. 155:A288.
19. Pedersen, B., P. Faurschou, F. Madsen, K. Viskum, T. Wilcke, and R. Dahl. 1996. Salmeterol treatment reduces the need for inhaled steroids in steroid dependent asthmatics - a randomised, double-blind, placebo-controlled parallel group study (abstract). Eur. Respir. J. 9:50s.
20. Rennard, S., K. Rickard, M. Wisniewski, J. Alexander, and the Salmeterol MDI Study Group. 1994. Comparison of daily markers of asthma in patients who experience exacerbations during maintenance treatment with salmeterol or albuterol (abstract). Am. J. Respir. Crit. Care Med. 149:A208.
21. Pauwels, R. A., C.-G. Lofdahl, D. S. Postma, A. E. Tattersfield, P. M. O'Byrne, P. J. Barnes, and A. Ullman. 1997. Effect of inhaled formoterol and hudesonide on exacerbations of asthma. N. Engl. J. Med. 337:1405-1411.
22. O'Connor, B. J., J. C. Kips, K. Svensson, R. A. Pauwels, and P. M. O'Byrne. 1998. Comparison of low dose hudesonide plus formoterol versus high dose hudesonide on markers of airway inflammation in asthma (abstract). Am. J. Respir. Crit. Care Med. 157:A415.
23. Pizzichini, M. M. M., J. C. Kidney, B. J. O. Wong, M. M. Morris, A. Efthimiadis, J. Dolovich, and F. E. Hargreave. 1996. Effect of salmeterol compared with beclomethasone on allergen-induced asthmatic and inflammatory responses. Eur. Respir. J. 9:449-455.
24. Wong, B. J., J. Dolovich, E. H. Ramsdale, P. M. O'Byrne, L. Gontovnick, J. A. Denburg, and F. E. Hargreave. 1992. Formoterol compared with beclomethasone and placebo on allergen-induced asthmatic responses. Am. Rev. Respir. Dis. 146:1156-1160.