Structural insights into the inhibited states of the Mer receptor tyrosine kinase

Journal of Structural Biology

Volumn 165, Issue 2, 2009, Pages 88-96

  Huang, Xudong ^a,b   Finerty Jr , Patrick ^a   Walker, John R ^a   Butler Cole, Christine ^a   Vedadi, Masoud ^a   Schapira, Matthieu ^a,b   Parker, Sirlester A ^c   Turk, Benjamin E ^c   Thompson, Debra A ^d   Dhe Paganon, Sirano ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Autoinhibition; Chemical probe; Kinase; Mer; MerTK; Screen; Structure

Indexed keywords

ADRENALIN; ETHANOLAMINE; FERRIC CHLORIDE; PROTEIN MERTK; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; LUNG EMBOLISM; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; CATALYTIC DOMAIN; DNA MUTATIONAL ANALYSIS; EPINEPHRINE; HUMANS; IMMUNE SYSTEM; MICE; MOLECULAR CONFORMATION; MUTATION; PEPTIDES; PHAGOCYTOSIS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; THROMBOSIS;

MAMMALIA; MUS;

EID: 58349115867     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2008.10.003     Document Type: Article

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