Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4). Protein kinase modulation and reactive oxygen species generation

Biochemical Pharmacology

Volumn 77, Issue 3, 2009, Pages 384-396

  Sánchez, Yolanda ^a   Amrán, Donna ^a   de Blas, Elena ^a   Aller, Patricio ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Differentiation; Genistein; Myeloid leukaemia cells; Oxidative stress; Protein kinases

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ARSENIC TRIOXIDE; ATM PROTEIN; CAFFEINE; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; GENISTEIN; ISOFLAVONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PROTEIN KINASE; PROTEIN KINASE B; RAF PROTEIN; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; SMALL INTERFERING RNA;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXICITY;

CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; ENZYME ACTIVATION; FLOW CYTOMETRY; GENISTEIN; HUMANS; LEUKEMIA, MYELOID, ACUTE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 58249139882     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.10.035     Document Type: Article

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