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Volumn 52, Issue 2, 2009, Pages 299-305

The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice

Author keywords

Diabetes; Interferon; Non obese diabetic mouse; Pancreas; Suppressor of cytokine signalling 1

Indexed keywords

GAMMA INTERFERON; GLUCOSE 6 PHOSPHATASE; LECTIN RECEPTOR; MESSENGER RNA;

EID: 58149476636     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-008-1193-7     Document Type: Article
Times cited : (10)

References (41)
  • 2
    • 17644361955 scopus 로고    scopus 로고
    • The NOD mouse: A model of immune dysregulation
    • MS Anderson JA Bluestone 2005 The NOD mouse: a model of immune dysregulation Annu Rev Immunol 23 447 485
    • (2005) Annu Rev Immunol , vol.23 , pp. 447-485
    • Anderson, M.S.1    Bluestone, J.A.2
  • 3
    • 0242268904 scopus 로고    scopus 로고
    • Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse
    • M Flodstrom-Tullberg D Yadav R Hagerkvist 2003 Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse Diabetes 52 2696 2700
    • (2003) Diabetes , vol.52 , pp. 2696-2700
    • Flodstrom-Tullberg, M.1    Yadav, D.2    Hagerkvist, R.3
  • 4
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • A Yoshimura T Naka M Kubo 2007 SOCS proteins, cytokine signalling and immune regulation Nat Rev Immunol 7 454 465
    • (2007) Nat Rev Immunol , vol.7 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 5
    • 38449090623 scopus 로고    scopus 로고
    • Functional waning of naturally-occurring CD4+ regulatory T cells contributes to the onset of autoimmune diabetes
    • M Tritt E Sgouroudis E d'Hennezel A Albanese CA Piccirillo 2008 Functional waning of naturally-occurring CD4+ regulatory T cells contributes to the onset of autoimmune diabetes Diabetes 57 113 123
    • (2008) Diabetes , vol.57 , pp. 113-123
    • Tritt, M.1    Sgouroudis, E.2    D'Hennezel, E.3    Albanese, A.4    Piccirillo, C.A.5
  • 6
    • 0037237655 scopus 로고    scopus 로고
    • Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
    • JD Trudeau C Kelly-Smith CB Verchere 2003 Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood J Clin Invest 111 217 223
    • (2003) J Clin Invest , vol.111 , pp. 217-223
    • Trudeau, J.D.1    Kelly-Smith, C.2    Verchere, C.B.3
  • 9
    • 12444252033 scopus 로고    scopus 로고
    • RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection
    • M Flodstrom-Tullberg M Hultcrantz A Stotland 2005 RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection J Immunol 174 1171 1177
    • (2005) J Immunol , vol.174 , pp. 1171-1177
    • Flodstrom-Tullberg, M.1    Hultcrantz, M.2    Stotland, A.3
  • 10
    • 34548682991 scopus 로고    scopus 로고
    • Interferons induce an antiviral state in human pancreatic islet cells
    • M Hultcrantz MH Huhn M Wolf 2007 Interferons induce an antiviral state in human pancreatic islet cells Virology 367 92 101
    • (2007) Virology , vol.367 , pp. 92-101
    • Hultcrantz, M.1    Huhn, M.H.2    Wolf, M.3
  • 11
    • 0036913215 scopus 로고    scopus 로고
    • Beta cells are responsible for CXCR3-mediated T cell infiltration in insulitis
    • S Frigerio T Junt B Lu 2002 Beta cells are responsible for CXCR3-mediated T cell infiltration in insulitis Nat Med 8 1414 1420
    • (2002) Nat Med , vol.8 , pp. 1414-1420
    • Frigerio, S.1    Junt, T.2    Lu, B.3
  • 12
    • 4444250373 scopus 로고    scopus 로고
    • IP-10 and type 1 diabetes: A question of time and location
    • U Christen MG von Herrath 2004 IP-10 and type 1 diabetes: a question of time and location Autoimmunity 37 273 282
    • (2004) Autoimmunity , vol.37 , pp. 273-282
    • Christen, U.1    Von Herrath, M.G.2
  • 13
    • 2942546678 scopus 로고    scopus 로고
    • NKG2D blockade prevents autoimmune diabetes in NOD mice
    • K Ogasawara JA Hamerman LR Ehrlich 2004 NKG2D blockade prevents autoimmune diabetes in NOD mice Immunity 20 757 767
    • (2004) Immunity , vol.20 , pp. 757-767
    • Ogasawara, K.1    Hamerman, J.A.2    Ehrlich, L.R.3
  • 14
    • 0037300827 scopus 로고    scopus 로고
    • IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice
    • AK Cardozo P Proost C Gysemans MC Chen C Mathieu DL Eizirik 2003 IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice Diabetologia 46 255 266
    • (2003) Diabetologia , vol.46 , pp. 255-266
    • Cardozo, A.K.1    Proost, P.2    Gysemans, C.3    Chen, M.C.4    Mathieu, C.5    Eizirik, D.L.6
  • 15
    • 0035889934 scopus 로고    scopus 로고
    • NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment
    • AI Roberts L Lee E Schwarz 2001 NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment J Immunol 167 5527 5530
    • (2001) J Immunol , vol.167 , pp. 5527-5530
    • Roberts, A.I.1    Lee, L.2    Schwarz, E.3
  • 16
    • 2142761669 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction
    • MM Chong Y Chen R Darwiche 2004 Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction J Immunol 172 5714 5721
    • (2004) J Immunol , vol.172 , pp. 5714-5721
    • Chong, M.M.1    Chen, Y.2    Darwiche, R.3
  • 17
    • 33646596928 scopus 로고    scopus 로고
    • Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
    • Y Liu I Teige B Birnir S Issazadeh-Navikas 2006 Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE Nat Med 12 518 525
    • (2006) Nat Med , vol.12 , pp. 518-525
    • Liu, Y.1    Teige, I.2    Birnir, B.3    Issazadeh-Navikas, S.4
  • 18
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Y Zheng AY Rudensky 2007 Foxp3 in control of the regulatory T cell lineage Nat Immunol 8 457 462
    • (2007) Nat Immunol , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 19
    • 33846550244 scopus 로고    scopus 로고
    • Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets
    • CP Wong R Stevens B Long 2007 Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets J Immunol 178 1388 1395
    • (2007) J Immunol , vol.178 , pp. 1388-1395
    • Wong, C.P.1    Stevens, R.2    Long, B.3
  • 20
    • 0034680105 scopus 로고    scopus 로고
    • Progression of autoimmune diabetes driven by avidity maturation of a T cell population
    • A Amrani J Verdaguer P Serra S Tafuro R Tan P Santamaria 2000 Progression of autoimmune diabetes driven by avidity maturation of a T cell population Nature 406 739 742
    • (2000) Nature , vol.406 , pp. 739-742
    • Amrani, A.1    Verdaguer, J.2    Serra, P.3    Tafuro, S.4    Tan, R.5    Santamaria, P.6
  • 21
    • 0037478632 scopus 로고    scopus 로고
    • Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
    • SM Lieberman AM Evans B Han 2003 Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes Proc Natl Acad Sci U S A 100 8384 8388
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8384-8388
    • Lieberman, S.M.1    Evans, A.M.2    Han, B.3
  • 22
    • 33645071052 scopus 로고    scopus 로고
    • Central tolerance: Good but imperfect
    • AM Gallegos MJ Bevan 2006 Central tolerance: good but imperfect Immunol Rev 209 290 296
    • (2006) Immunol Rev , vol.209 , pp. 290-296
    • Gallegos, A.M.1    Bevan, M.J.2
  • 23
    • 15244355148 scopus 로고    scopus 로고
    • Peripheral tolerance of CD8 T lymphocytes
    • WL Redmond LA Sherman 2005 Peripheral tolerance of CD8 T lymphocytes Immunity 22 275 284
    • (2005) Immunity , vol.22 , pp. 275-284
    • Redmond, W.L.1    Sherman, L.A.2
  • 24
    • 0033520326 scopus 로고    scopus 로고
    • SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
    • WS Alexander R Starr JE Fenner 1999 SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine Cell 98 597 608
    • (1999) Cell , vol.98 , pp. 597-608
    • Alexander, W.S.1    Starr, R.2    Fenner, J.E.3
  • 25
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
    • DL Eizirik T Mandrup-Poulsen 2001 A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis Diabetologia 44 2115 2133
    • (2001) Diabetologia , vol.44 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 26
    • 0035834171 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 (SOCS-3) protects beta-cells against interleukin-1beta- and interferon-gamma-mediated toxicity
    • AE Karlsen SG Ronn K Lindberg 2001 Suppressor of cytokine signaling 3 (SOCS-3) protects beta-cells against interleukin-1beta- and interferon-gamma- mediated toxicity Proc Natl Acad Sci U S A 98 12191 12196
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12191-12196
    • Karlsen, A.E.1    Ronn, S.G.2    Lindberg, K.3
  • 27
    • 33750578280 scopus 로고    scopus 로고
    • CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets
    • FM Barbe-Tuana D Klein H Ichii 2006 CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets Diabetes 55 2437 2445
    • (2006) Diabetes , vol.55 , pp. 2437-2445
    • Barbe-Tuana, F.M.1    Klein, D.2    Ichii, H.3
  • 28
    • 0346366975 scopus 로고    scopus 로고
    • Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens
    • J Yamanouchi J Verdaguer B Han A Amrani P Serra P Santamaria 2003 Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens J Immunol 171 6900 6909
    • (2003) J Immunol , vol.171 , pp. 6900-6909
    • Yamanouchi, J.1    Verdaguer, J.2    Han, B.3    Amrani, A.4    Serra, P.5    Santamaria, P.6
  • 29
    • 33750602224 scopus 로고    scopus 로고
    • Cytotoxic T cells from T cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways
    • NL Dudek HE Thomas L Mariana 2006 Cytotoxic T cells from T cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways Diabetes 55 2412 2418
    • (2006) Diabetes , vol.55 , pp. 2412-2418
    • Dudek, N.L.1    Thomas, H.E.2    Mariana, L.3
  • 30
    • 33845995044 scopus 로고    scopus 로고
    • SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes
    • AM Barral HE Thomas EM Ling 2006 SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes J Autoimmun 27 166 173
    • (2006) J Autoimmun , vol.27 , pp. 166-173
    • Barral, A.M.1    Thomas, H.E.2    Ling, E.M.3
  • 31
    • 34548397755 scopus 로고    scopus 로고
    • Screening for insulitis in adult autoantibody-positive organ donors
    • P In't Veld D Lievens J de Grijse 2007 Screening for insulitis in adult autoantibody-positive organ donors Diabetes 56 2400 2404
    • (2007) Diabetes , vol.56 , pp. 2400-2404
    • In'T Veld, P.1    Lievens, D.2    De Grijse, J.3
  • 32
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
    • GF Bottazzo BM Dean JM McNally EH MacKay PG Swift DR Gamble 1985 In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis N Engl J Med 313 353 360
    • (1985) N Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1    Dean, B.M.2    McNally, J.M.3    MacKay, E.H.4    Swift, P.G.5    Gamble, D.R.6
  • 33
    • 34247627376 scopus 로고    scopus 로고
    • Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
    • F Dotta S Censini AG van Halteren 2007 Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients Proc Natl Acad Sci U S A 104 5115 5120
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5115-5120
    • Dotta, F.1    Censini, S.2    Van Halteren, A.G.3
  • 34
    • 0026492896 scopus 로고
    • Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus
    • A Hanninen S Jalkanen M Salmi S Toikkanen G Nikolakaros O Simell 1992 Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus J Clin Invest 90 1901 1910
    • (1992) J Clin Invest , vol.90 , pp. 1901-1910
    • Hanninen, A.1    Jalkanen, S.2    Salmi, M.3    Toikkanen, S.4    Nikolakaros, G.5    Simell, O.6
  • 35
    • 0028278373 scopus 로고
    • Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor v beta usage, and cytokine profile
    • N Somoza F Vargas C Roura-Mir 1994 Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile J Immunol 153 1360 1377
    • (1994) J Immunol , vol.153 , pp. 1360-1377
    • Somoza, N.1    Vargas, F.2    Roura-Mir, C.3
  • 36
    • 0036372419 scopus 로고    scopus 로고
    • Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed type i diabetes mellitus patients and subjects at risk of developing the disease
    • F Nicoletti I Conget M Di Mauro 2002 Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed type I diabetes mellitus patients and subjects at risk of developing the disease Diabetologia 45 1107 1110
    • (2002) Diabetologia , vol.45 , pp. 1107-1110
    • Nicoletti, F.1    Conget, I.2    Di Mauro, M.3
  • 37
    • 12944319826 scopus 로고    scopus 로고
    • Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice
    • AG van Halteren MJ Kardol A Mulder BO Roep 2005 Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice Diabetologia 48 75 82
    • (2005) Diabetologia , vol.48 , pp. 75-82
    • Van Halteren, A.G.1    Kardol, M.J.2    Mulder, A.3    Roep, B.O.4
  • 40
    • 34249107054 scopus 로고    scopus 로고
    • Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men
    • WW Unger GG Pinkse S Mulder-van der Kracht 2007 Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men Ann N Y Acad Sci 1103 192 195
    • (2007) Ann N y Acad Sci , vol.1103 , pp. 192-195
    • Unger, W.W.1    Pinkse, G.G.2    Mulder-Van Der Kracht, S.3
  • 41
    • 0346366978 scopus 로고    scopus 로고
    • Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease
    • U Christen DB McGavern AD Luster MG von Herrath MB Oldstone 2003 Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease J Immunol 171 6838 6845
    • (2003) J Immunol , vol.171 , pp. 6838-6845
    • Christen, U.1    McGavern, D.B.2    Luster, A.D.3    Von Herrath, M.G.4    Oldstone, M.B.5


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