1,3-Capryloyl-2-arachidonoyl glycerol activates α-secretase activity and suppresses Aβ40 secretion in A172 cells

Neuroscience Letters

Volumn 450, Issue 3, 2009, Pages 324-326

  Tanabe, Chiaki ^a   Ebina, Maiko ^a   Asai, Masashi ^b   Futai, Eugene ^a   Sasagawa, Noboru ^a   Katano, Kenji ^c   Fukami, Harukazu ^d   Ishiura, Shoichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c SUNTORY LTD   (Japan)

^d Ukyo ku   (Japan)

Author keywords

Secretase; Secretase; Alzheimer's disease; Amyloid precursor protein (APP); Arachidonic acid; Medium chain fatty acid

Indexed keywords

1,3 CAPRYLOYL 2 ARACHIDONOYLGLYCEROL; 2 ARACHIDONOYLGLYCEROL; 8A8; ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-40]; BETA SECRETASE; OCTANOIC ACID; POLYUNSATURATED FATTY ACID; SECRETASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIPID MEMBRANE; MEMBRANE FLUIDITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; BRAIN; CAPRYLATES; CELL LINE; CELL LINE, TUMOR; DOWN-REGULATION; ENZYME ACTIVATION; FATTY ACIDS, UNSATURATED; HUMANS; NEURONS; PEPTIDE FRAGMENTS; TRIGLYCERIDES;

EID: 58149470372     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.11.039     Document Type: Article

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