Arachidonic acid improves aged rats' spatial cognition

Physiology and Behavior

Volumn 84, Issue 4, 2005, Pages 617-623

  Okaichi, Yoko ^a   Ishikura, Yoshiyuki ^b   Akimoto, Kengo ^b   Kawashima, Hiroshi ^b   Toyoda Ono, Yoshiko ^b   Kiso, Yoshinobu ^b   Okaichi, Hiroshige ^a  

^a DOSHISHA UNIVERSITY   (Japan)

^b SUNTORY LTD   (Japan)

Author keywords

Aged rats; Arachidonic acid; Cue task; Morris water maze; Place task; Spatial cognition

Indexed keywords

ARA VITA; ARACHIDONIC ACID; FATTY ACID; NOOTROPIC AGENT; PHOSPHOLIPID;

AGED; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BRAIN LEVEL; CHEMICAL COMPOSITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEPTH PERCEPTION; DIET SUPPLEMENTATION; DRUG EFFECT; ESCAPE BEHAVIOR; HIPPOCAMPUS; LATENT PERIOD; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; REGRESSION ANALYSIS; TASK PERFORMANCE;

EID: 16844364451     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2005.02.008     Document Type: Article

References (31)

1. M. Gallagher, and R.D. Burwell Relationship of age-related decline across several behavioral domains Neurobiol Aging 10 1989 691 708
2. M.D. Lindner Reliability, distribution, and validity of age-related cognitive deficits in the Morris water maze Neurobiol Learn Mem 68 1997 203 220
3. Y. Okaichi Spatial behavior of the rat: in relation to the hippocampal functions Jpn J Anim Psychol 52 2002 89 96 [in Japanese]
4. P.R. Rapp, R.A. Rosenberg, and M. Gallagher An evaluation of spatial information processing in aged rats Behav Neurosci 101 1987 3 12
5. F.J. van der Staay Shift in the performance of 24-month-old Wistar rats in the Morris water escape task: a comparison across 36 experiments Behav Brain Res 87 1997 213 222
6. A. Caprioli, O. Ghirardi, A. Giuliani, M.T. Ramacci, and L. Angelucci Spatial learning and memory in the radial maze: a longitudinal study in rats from 4 to 25 months of age Neurobiol Aging 12 1991 605 607
7. S. Ikegami Behavioral impairment in radial-arm maze learning and acetylcholine content of the hippocampus and cerebral cortex in aged mice Behav Brain Res 65 1994 103 111
8. T. Kadar, M. Silbermann, R. Brandeis, and A. Levy Age-related structural changes in the rat hippocampus: correlation with working memory deficiency Brain Res 512 1990 113 120
9. S.J.Y. Mizumori, A.M. Lavoie, and A. Kalyani Redistribution of spatial representation in the hippocampus of aged rats performing a spatial memory task Behav Neurosci 110 1996 1006 1016
10. S.J.Y. Mizumori, and A. Kalyani Age and experience-dependent representational organization during spatial learning Neurobiol Aging 18 1997 651 659
11. G. Winocur, and S. Gagnon Glucose treatment attenuates spatial learning and memory deficits of aged rats on tests of hippocampal function Neurobiol Aging 19 1998 233 241
12. C.A. Barnes Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat J Comp Physiol Psychol 93 1979 74 104
13. C.A. Barnes, L. Nadel, and W.K. Honig Spatial memory deficit in senescent rats Can J Psychol 34 1980 29 39
14. C.A. Barnes, and B.L. McNaughton An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses Behav Neurosci 99 1985 1040 1048
15. E.S. Rosenzweig, G. Rao, B.L. McNaughton, and C.A. Barnes Role of temporal summation in age-related long-term potentiation-induction deficits Hippocampus 7 1997 549 558
16. G. Diana, M.R. Domenicia, A.S. de Carolisa, A. Loizzoa, and S. Sagratellaa Reduced hippocampal CA1 Ca2+-induced long-term potentiation is associated with age-dependent impairment of spatial learning Brain Res 686 1995 107 110
17. M.A. Lynch, K.L. Voss, and A.J. Gower Impaired spatial memory in aged rats is associated with alterations in inositol phospholipid metabolism Neuro Rep 5 1994 1493 1497
18. M.A. Lynch, and K.L. Voss Membrane arachidonic acid concentration correlates with age and induction of long-term potentiation in the dentate gyrus in the rat Eur J Neurosci 6 1994 1008 1014
19. C.A. Murray, and M.A. Lynch Evidence that increased hippocampal expression of the cytokine interleukin-1 β is a common trigger for age- and stress-induced impairments in long-term potentiation J Neurosci 18 1998 2974 2981
20. S. Kotani, H. Nakazawa, T. Tokimasa, K. Akimoto, H. Kawashima, and Y. Toyoda-Ono Synaptic plasticity preserved with arachidonic acid diet in aged rats Neurosci Res 46 2003 453 461
21. B. McGahon, M.P. Clements, and M.A. Lynch The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed Neuroscience 81 1997 9 16
22. B. McGahon, C.A. Murray, M.P. Clements, and M.A. Lynch Analysis of the effect of membrane arachidonic acid concentration on modulation of glutamate release by interleukin-1: an age-related study Exp Gerontol 33 1998 343 354
23. S. Gamoh, M. Hashimoto, S. Hossain, and S. Masumura Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats Clin Exp Pharmacol Physiol 28 2001 266 270
24. S.Y. Lim, and H. Suzuki Intakes of dietary docosahexaenoic acid ethyl ester and egg phosphatidylcholine improve maze-learning ability in young and old mice J Nutr 130 2000 1629 1632
25. Y. Sugimoto, C. Taga, M. Nishiga, M. Fujiwara, F. Konishi, and K. Tanaka Effect of docosahexaenoic acid-fortified Chlorella vulgaris strain CK22 on the radial maze performance in aged mice Biol Pharm Bull 25 2002 1090 1092
26. R.G.M. Morris Spatial localization does not require the presence of local cues Learn Motiv 12 1981 239 260
27. H. Okaichi Effects of dorsal-striatum lesions and fimbria-fornix lesions on the problem-solving strategies of rats in a shallow water maze Cog Affect Behav Neurosci 1 2001 229 238
28. J. Folch, M. Lees, and G.H.S. Stanley A simple method for the isolation and purification of total lipids from animal tissues J Biol Chem 226 1957 497 509
29. E. Sakuradani, M. Kobayashi, and S. Shimizu Δ9-Fatty acid desaturase from arachidonic acid-producing fungus: unique gene sequence and its heterologous expression in a fungus Eur J Biochem 260 1999 208 216
30. F.J. van der Staay, and M. de Jonge Effects of age on water escape behavior and on repeated acquisition in rats Behav Neural Biol 60 1993 33 41
31. E.L. Lien, F.G. Boyle, R.J. Yuhas, and C.F. Kuhlman Effect of maternal dietary arachidonic or linoleic acid on rat pup fatty acid profiles Lipids 29 1994 53 59