Evaluation of drug-metabolizing and functional competence of human hepatocytes incubated under hypothermia in different media for clinical infusion

Cell Transplantation

Volumn 17, Issue 8, 2008, Pages 887-897

  Gómez Lechón, María José ^a,b   Lahoz, Agustín ^a   Jiménez, Nuria ^a,b   Bonora, Ana ^a,b   Castell, José V ^a,b,c   Donato, María Teresa ^a,b,c  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b FIS   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Apoptosis; Glycogen; Hepatocytes; Hypothermia; Infusion medium; N acetyl cystein; P450 enzymes; Ureogenesis

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ANTICOAGULANT AGENT; CASPASE 3; CYTOCHROME P450; DRUG METABOLIZING ENZYME; GLUCOSE; GLUTATHIONE; GLYCOGEN; PHOSPHATE BUFFERED SALINE; SERUM ALBUMIN; CASPASE; UREA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; CULTURE MEDIUM; FUNCTIONAL ASSESSMENT; HEPATOCYTE TRANSPLANTATION; INCUBATION TIME; INFUSION SYSTEM; MALE; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SUSPENSION CELL CULTURE; UREA CYCLE; ANIMAL; CELL ADHESION; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CULTURE TECHNIQUE; DRUG DETOXIFICATION; DRUG EFFECT; ENERGY METABOLISM; HUMAN; HYPERTHERMIC THERAPY; LIVER CELL; LIVER DISEASE; METABOLISM; METHODOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TISSUE TRANSPLANTATION; TRANSPLANTATION;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CASPASES; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA; CYTOCHROME P-450 ENZYME SYSTEM; ENERGY METABOLISM; GLUCOSE; HEPATOCYTES; HUMANS; HYPERTHERMIA, INDUCED; LIVER DISEASES; MALE; METABOLIC DETOXICATION, DRUG; RATS; RATS, SPRAGUE-DAWLEY; TISSUE TRANSPLANTATION; UREA;

EID: 58149373639     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368908786576534     Document Type: Article

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