Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury

Hepatology

Volumn 32, Issue 2, 2000, Pages 169-173

  Lentsch, Alex B ^a   Kato, Atsushi ^a   Yoshidome, Hiroyuki ^a   McMasters, Kelly M ^a   Edwards, Michael J ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN EXPRESSION; CYTOKINE PRODUCTION; IMMUNOREGULATION; INFLAMMATION; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LIVER CELL DAMAGE; LIVER ISCHEMIA; LIVER PROTECTION; LIVER REGENERATION; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW;

EID: 0033853801     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.9323     Document Type: Article

References (53)

1. Hepatic resection with ischemia of the liver exceeding one hour
2. Multiple-system organ damage resulting from prolonged hepatic inflow interruption
3. Reperfusion injury after liver preservation for transplantation
4. Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock
5. Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver
6. Neutrophil and Kupffer cell-induced oxidant stress and ischemia- reperfusion injury in rat liver
7. Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia
8. Reactive oxygen and ischemia/reperfusion injury of the liver
9. Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia
10. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo
11. Liver ischemia and reperfusion induces a systemic inflammatory response through Kupffer cell activation
12. Activation of nuclear factor-κB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells
13. Kupffer cell depletion abolishes induction of interleukin-10 and permits sustained overexpression of tumor necrosis factor alpha messenger RNA in the regenerating rat liver
14. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice
15. Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat
16. The production of tumor necrosis factor alpha and the development of a pulmonary capillary injury following hepatic ischemia/reperfusion
17. Tumor necrosis factor up-regulates intercellular adhesion molecule 1, which is important in the neutrophil-dependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat
18. Role of P-selectin expression in hepatic ischemia and reperfusion injury
19. Hepatic ischemia-reperfusion injury causes E-selectin upregulation
20. L-selectin and ICAM-1 mediate reperfusion injury and neutrophil adhesion in the warm ischemic mouse liver
21. P-selectin contributes to the initial recruitment of rolling and adherent leukocytes in hepatic venules after ischemia/reperfusion
22. P-selectin mediates reperfusion injury through neutrophil and platelet sequestration in the warm ischemic mouse liver
23. Platelets induced sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver
24. Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver
25. Intercellular adhesion molecule1 (ICAM-1) expression and its role in neutrophil-induced ischemia-reperfusion injury in rat liver
26. Chemokines - chemotactic cytokines that mediate inflammation
27. Chemokine expression during hepatic ischemia/reperfusion-induced lung injury in the rat. The role of epithelial neutrophil activating protein
28. Chemokine involvement in hepatic ischemia/reperfusion injury in mice: Roles for macrophage inflammatory protein-2 and KC
29. Enhanced pulmonary expression of CXC chemokines during hepatic ischemia/reperfusion-induced lung injury in mice
30. Ischemia-reperfusion injury: The role of Kupffer cells in the production of cytokine-induced neutrophil chemoattractant, a member of the interleukin-8 family
31. CD18 integrin and CD54-dependent neutrophil adhesion to cytokine- stimulated human hepatocytes
32. Listeria monocytogenes infection increases neutrophil adhesion and damage to a murine hepatocyte cell line in vitro
33. Trilox protects rat hepatocytes against oxyradical damage and the ischemic rat liver from reperfusion injury
34. In vitro toxicity of polymorphonuclear neutrophils to rat hepatocytes: Evidence for a proteinase-mediated mechanism
35. Effect of protease inhibitor on ischemia-reperfusion injury of the rat liver
36. Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent
37. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: Implications of a central role for nuclear factor κB
38. Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion
39. NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
40. Ischemia/reperfusion injury in the liver of BALB/C mice activates AP-1 and nuclear factor κB independently of IκB degradation
41. In vivo suppression of NF-κB and preservation of IκB alpha by interleukin-10 and interleukin-13
42. Inhibition of NF-κB activation and augmentation of IκBβ by secretory leukocyte protease inhibitor during lung inflammation
43. Protective effect of ischemic preconditioning on liver preservation- reperfusion injury in rats
44. Preconditioning protects against ischemia/reperfusion injury of the liver
45. Protective effect of liver ischemic preconditioning on liver and lung injury induced by hepatic ischemia-reperfusion in the rat
46. The role of ischemic preconditioning in the recruitment of roiling and adherent leukocytes in hepatic venules after ischemia/reperfusion
47. Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat
48. Cytokines and adhesion molecules in elective and accidental trauma- related ischemia/reperfusion
49. Pilot clinical trial of an anti-TNFa monoclonal antibody for the treatment of septic shock
50. Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial. The interleukin-1 receptor antagonist sepsis investigator group
51. IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion
52. Reduced hepatic ischemia/reperfusion injury by IL-4: Potential anti- inflammatory role of STAT6
53. Regulation of inflammatory liver injury by STAT6