-
1
-
-
0025892694
-
Insulin stimulation of gene expression mediated by p21ras activation
-
Burgering BM, Medema RH, Maassen JA, van de Wetering ML, van der Eb AJ, McCormick F et al. (1991). Insulin stimulation of gene expression mediated by p21ras activation. EMBO J 10: 1103-1109.
-
(1991)
EMBO J
, vol.10
, pp. 1103-1109
-
-
Burgering, B.M.1
Medema, R.H.2
Maassen, J.A.3
van de Wetering, M.L.4
van der Eb, A.J.5
McCormick, F.6
-
2
-
-
0033869876
-
Translational control of C/EBPalpha and C/EBPbeta isoform expression
-
Calkhoven CF, Muller C, Leutz A. (2000). Translational control of C/EBPalpha and C/EBPbeta isoform expression. Genes Dev 14: 1920-1932.
-
(2000)
Genes Dev
, vol.14
, pp. 1920-1932
-
-
Calkhoven, C.F.1
Muller, C.2
Leutz, A.3
-
3
-
-
0037017396
-
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
-
Dijkers PF, Birkenkamp KU, Lam EW, Thomas NS, Lammers JW, Koenderman L et al. (2002b). FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 156: 531-542.
-
(2002)
J Cell Biol
, vol.156
, pp. 531-542
-
-
Dijkers, P.F.1
Birkenkamp, K.U.2
Lam, E.W.3
Thomas, N.S.4
Lammers, J.W.5
Koenderman, L.6
-
4
-
-
0037017396
-
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
-
Dijkers PF, Birkenkamp KU, Lam EW, Thomas NS, Lammers JW, Koenderman L et al. (2002a). FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 156: 531-542.
-
(2002)
J Cell Biol
, vol.156
, pp. 531-542
-
-
Dijkers, P.F.1
Birkenkamp, K.U.2
Lam, E.W.3
Thomas, N.S.4
Lammers, J.W.5
Koenderman, L.6
-
5
-
-
0021228666
-
Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation
-
Duncan R, Hershey JW. (1984). Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation. J Biol Chem 259: 11882-11889.
-
(1984)
J Biol Chem
, vol.259
, pp. 11882-11889
-
-
Duncan, R.1
Hershey, J.W.2
-
6
-
-
0022260969
-
Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification
-
Duncan R, Hershey JW. (1985). Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification. J Biol Chem 260: 5493-5497.
-
(1985)
J Biol Chem
, vol.260
, pp. 5493-5497
-
-
Duncan, R.1
Hershey, J.W.2
-
7
-
-
0017235694
-
The nucleoli of cultured human lymphocytes. I nucleolar morphology in relation to transformation and the DNA cycle
-
Gani R. (1976). The nucleoli of cultured human lymphocytes. I nucleolar morphology in relation to transformation and the DNA cycle. Exp Cell Res 97: 249-258.
-
(1976)
Exp Cell Res
, vol.97
, pp. 249-258
-
-
Gani, R.1
-
8
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta
-
Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL et al. (2003). Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta. J Clin Invest 112: 197-208.
-
(2003)
J Clin Invest
, vol.112
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
-
9
-
-
0032834055
-
eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
-
Gingras AC, Raught B, Sonenberg N. (1999). eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 68: 913-963.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 913-963
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
10
-
-
23144467910
-
An expanding role for mTOR in cancer
-
Guertin DA, Sabatini DM. (2005). An expanding role for mTOR in cancer. Trends Mol Med 11: 353-361.
-
(2005)
Trends Mol Med
, vol.11
, pp. 353-361
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
11
-
-
0000091608
-
Pathway and mechanism of initiation of protein synthesis
-
Sonenberg N, Hershey JWB, Merrick WC eds, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, pp
-
Hershey JW, Merrick WC. (2000). Pathway and mechanism of initiation of protein synthesis. In: Sonenberg N, Hershey JWB, Merrick WC (eds). Translational Control of Gene Expression. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, pp 33-88.
-
(2000)
Translational Control of Gene Expression
, pp. 33-88
-
-
Hershey, J.W.1
Merrick, W.C.2
-
12
-
-
2342639670
-
Signaling control of mRNA translation in cancer pathogenesis
-
Holland EC, Sonenberg N, Pandolfi PP, Thomas G. (2004b). Signaling control of mRNA translation in cancer pathogenesis. Oncogene 23: 3138-3144.
-
(2004)
Oncogene
, vol.23
, pp. 3138-3144
-
-
Holland, E.C.1
Sonenberg, N.2
Pandolfi, P.P.3
Thomas, G.4
-
13
-
-
2342639670
-
Signaling control of mRNA translation in cancer pathogenesis
-
Holland EC, Sonenberg N, Pandolfi PP, Thomas G. (2004a). Signaling control of mRNA translation in cancer pathogenesis. Oncogene 23: 3138-3144.
-
(2004)
Oncogene
, vol.23
, pp. 3138-3144
-
-
Holland, E.C.1
Sonenberg, N.2
Pandolfi, P.P.3
Thomas, G.4
-
14
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz MK, Ballif BA, Gygi SP, Blenis J. (2005). mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123: 569-580.
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
15
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. (2002). TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4: 648-657.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
16
-
-
24944519450
-
Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns
-
Larsen MR, Thingholm TE, Jensen ON, Roepstorff P, Jorgensen TJ. (2005). Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns. Mol Cell Proteomics 4: 873-886.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 873-886
-
-
Larsen, M.R.1
Thingholm, T.E.2
Jensen, O.N.3
Roepstorff, P.4
Jorgensen, T.J.5
-
17
-
-
0024356599
-
Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay
-
Lawson TG, Lee KA, Maimone MM, Abramson RD, Dever TE, Merrick WC et al. (1989). Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay. Biochemistry 28: 4729-4734.
-
(1989)
Biochemistry
, vol.28
, pp. 4729-4734
-
-
Lawson, T.G.1
Lee, K.A.2
Maimone, M.M.3
Abramson, R.D.4
Dever, T.E.5
Merrick, W.C.6
-
18
-
-
0016910350
-
Translational control of protein synthesis
-
Lodish HF. (1976). Translational control of protein synthesis. Annu Rev Biochem 45: 39-72.
-
(1976)
Annu Rev Biochem
, vol.45
, pp. 39-72
-
-
Lodish, H.F.1
-
19
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
Luo J, Manning BD, Cantley LC. (2003). Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4: 257-262.
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
20
-
-
33750068623
-
mTOR, translation initiation and cancer
-
Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N. (2006). mTOR, translation initiation and cancer. Oncogene 25: 6416-6422.
-
(2006)
Oncogene
, vol.25
, pp. 6416-6422
-
-
Mamane, Y.1
Petroulakis, E.2
LeBacquer, O.3
Sonenberg, N.4
-
21
-
-
0028331455
-
The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence
-
Methot N, Pause A, Hershey JW, Sonenberg N. (1994). The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence. Mol Cell Biol 14: 2307-2316.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2307-2316
-
-
Methot, N.1
Pause, A.2
Hershey, J.W.3
Sonenberg, N.4
-
22
-
-
0029805730
-
In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: The role of the RNA remotif
-
Methot N, Pickett G, Keene JD, Sonenberg N. (1996a). In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif. RNA 2: 38-50.
-
(1996)
RNA
, vol.2
, pp. 38-50
-
-
Methot, N.1
Pickett, G.2
Keene, J.D.3
Sonenberg, N.4
-
23
-
-
0039799706
-
A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3
-
Methot N, Song MS, Sonenberg N. (1996b). A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3. Mol Cell Biol 16: 5328-5334.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5328-5334
-
-
Methot, N.1
Song, M.S.2
Sonenberg, N.3
-
24
-
-
0028285942
-
Two structural domains of initiation factor eIF-4B are involved in binding to RNA
-
Naranda T, Strong WB, Menaya J, Fabbri BJ, Hershey JW. (1994). Two structural domains of initiation factor eIF-4B are involved in binding to RNA. J Biol Chem 269: 14465-14472.
-
(1994)
J Biol Chem
, vol.269
, pp. 14465-14472
-
-
Naranda, T.1
Strong, W.B.2
Menaya, J.3
Fabbri, B.J.4
Hershey, J.W.5
-
25
-
-
0033429554
-
Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation
-
Nave BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR. (1999). Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J 344(Pt 2): 427-431.
-
(1999)
Biochem J
, vol.344
, Issue.PART 2
, pp. 427-431
-
-
Nave, B.T.1
Ouwens, M.2
Withers, D.J.3
Alessi, D.R.4
Shepherd, P.R.5
-
26
-
-
26444575415
-
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
-
Nobukuni T, Joaquin M, Roccio M, Dann SG, Kim SY, Gulati P et al. (2005). Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. Proc Natl Acad Sci USA 102: 14238-14243.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14238-14243
-
-
Nobukuni, T.1
Joaquin, M.2
Roccio, M.3
Dann, S.G.4
Kim, S.Y.5
Gulati, P.6
-
27
-
-
0034680838
-
Peptide and protein library screening defines optimal substrate motifs for AKT/PKB
-
Obata T, Yaffe MB, Leparc GG, Piro ET, Maegawa H, Kashiwagi A et al. (2000). Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem 275: 36108-36115.
-
(2000)
J Biol Chem
, vol.275
, pp. 36108-36115
-
-
Obata, T.1
Yaffe, M.B.2
Leparc, G.G.3
Piro, E.T.4
Maegawa, H.5
Kashiwagi, A.6
-
28
-
-
0042622251
-
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
-
Obenauer JC, Cantley LC, Yaffe MB. (2003). Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res 31: 3635-3641.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3635-3641
-
-
Obenauer, J.C.1
Cantley, L.C.2
Yaffe, M.B.3
-
29
-
-
2342538485
-
Aberrant mRNA translation in cancer pathogenesis: An old concept revisited comes finally of age
-
Pandolfi PP. (2004). Aberrant mRNA translation in cancer pathogenesis: an old concept revisited comes finally of age. Oncogene 23: 3134-3137.
-
(2004)
Oncogene
, vol.23
, pp. 3134-3137
-
-
Pandolfi, P.P.1
-
30
-
-
0035213641
-
AGC protein kinase phosphorylation and protein kinase C
-
Parker PJ, Parkinson SJ. (2001). AGC protein kinase phosphorylation and protein kinase C. Biochem Soc Trans 29: 860-863.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 860-863
-
-
Parker, P.J.1
Parkinson, S.J.2
-
31
-
-
0242361561
-
Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes
-
Rajasekhar VK, Viale A, Socci ND, Wiedmann M, Hu X, Holland EC. (2003). Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes. Mol Cell 12: 889-901.
-
(2003)
Mol Cell
, vol.12
, pp. 889-901
-
-
Rajasekhar, V.K.1
Viale, A.2
Socci, N.D.3
Wiedmann, M.4
Hu, X.5
Holland, E.C.6
-
32
-
-
0001902617
-
Regulation of ribosomal recruitment in eukaryotes
-
Sonenberg N, Hershey JWB, Merrick WC eds, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, pp
-
Raught B, Gingras AC, Sonenberg N. (2000). Regulation of ribosomal recruitment in eukaryotes. In: Sonenberg N, Hershey JWB, Merrick WC (eds). Translational Control of Gene Expression. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, pp 245-295.
-
(2000)
Translational Control of Gene Expression
, pp. 245-295
-
-
Raught, B.1
Gingras, A.C.2
Sonenberg, N.3
-
33
-
-
2442574729
-
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
-
Raught B, Peiretti F, Gingras AC, Livingstone M, Shahbazian D, Mayeur GL et al. (2004). Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J 23: 1761-1769.
-
(2004)
EMBO J
, vol.23
, pp. 1761-1769
-
-
Raught, B.1
Peiretti, F.2
Gingras, A.C.3
Livingstone, M.4
Shahbazian, D.5
Mayeur, G.L.6
-
34
-
-
13444259647
-
Regulation of cap-dependent translation by eIF4E inhibitory proteins
-
Richter JD, Sonenberg N. (2005). Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433: 477-480.
-
(2005)
Nature
, vol.433
, pp. 477-480
-
-
Richter, J.D.1
Sonenberg, N.2
-
35
-
-
0035903136
-
Modulation of the helicase activity of eIF4A by eIF4B, eIF4 H, and eIF4F
-
Rogers Jr GW, Richter NJ, Lima WF, Merrick WC. (2001). Modulation of the helicase activity of eIF4A by eIF4B, eIF4 H, and eIF4F. J Biol Chem 276: 30914-30922.
-
(2001)
J Biol Chem
, vol.276
, pp. 30914-30922
-
-
Rogers Jr, G.W.1
Richter, N.J.2
Lima, W.F.3
Merrick, W.C.4
-
36
-
-
0025176473
-
Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F
-
Rozen F, Edery I, Meerovitch K, Dever TE, Merrick WC, Sonenberg N. (1990). Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F. Mol Cell Biol 10: 1134-1144.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 1134-1144
-
-
Rozen, F.1
Edery, I.2
Meerovitch, K.3
Dever, T.E.4
Merrick, W.C.5
Sonenberg, N.6
-
37
-
-
2442648845
-
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
-
Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C et al. (2004). The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nat Med 10: 484-486.
-
(2004)
Nat Med
, vol.10
, pp. 484-486
-
-
Ruggero, D.1
Montanaro, L.2
Ma, L.3
Xu, W.4
Londei, P.5
Cordon-Cardo, C.6
-
38
-
-
0037363075
-
Does the ribosome translate cancer?
-
Ruggero D, Pandolfi PP. (2003). Does the ribosome translate cancer? Nat Rev Cancer 3: 179-192.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 179-192
-
-
Ruggero, D.1
Pandolfi, P.P.2
-
39
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF et al. (2006). Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 22: 159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
-
40
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. (2005). Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
41
-
-
33745570504
-
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
-
Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J et al. (2006). The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J 25: 2781-2791.
-
(2006)
EMBO J
, vol.25
, pp. 2781-2791
-
-
Shahbazian, D.1
Roux, P.P.2
Mieulet, V.3
Cohen, M.S.4
Raught, B.5
Taunton, J.6
-
42
-
-
33845340834
-
Chronic Protein Kinase B (PKB/c-akt) Activation Leads to Apoptosis Induced by Oxidative Stress-Mediated Foxo3a Transcriptional Up-regulation
-
van Gorp AG, Pomeranz KM, Birkenkamp KU, Hui RC, Lam EW, Coffer PJ. (2006). Chronic Protein Kinase B (PKB/c-akt) Activation Leads to Apoptosis Induced by Oxidative Stress-Mediated Foxo3a Transcriptional Up-regulation. Cancer Res 66: 10760-10769.
-
(2006)
Cancer Res
, vol.66
, pp. 10760-10769
-
-
van Gorp, A.G.1
Pomeranz, K.M.2
Birkenkamp, K.U.3
Hui, R.C.4
Lam, E.W.5
Coffer, P.J.6
-
43
-
-
33644856280
-
A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell
-
Wiesenthal V, Leutz A, Calkhoven CF. (2006). A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell. Nucleic Acids Res 34: e23.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Wiesenthal, V.1
Leutz, A.2
Calkhoven, C.F.3
-
44
-
-
0037131411
-
Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs
-
Zhang H, Zha X, Tan Y, Hornbeck PV, Mastrangelo AJ, Alessi DR et al. (2002). Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs. J Biol Chem 277: 39379-39387.
-
(2002)
J Biol Chem
, vol.277
, pp. 39379-39387
-
-
Zhang, H.1
Zha, X.2
Tan, Y.3
Hornbeck, P.V.4
Mastrangelo, A.J.5
Alessi, D.R.6
|