Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis

Brain Research

Volumn 1250, Issue , 2009, Pages 63-74

  Loucks, F Alexandra ^a   Schroeder, Emily K ^a   Zommer, Amelia E ^b   Hilger, Shea ^c   Kelsey, Natalie A ^b   Bouchard, Ron J ^a   Blackstone, Craig ^d   Brewster, Jay L ^c   Linseman, Daniel A ^a,b,e  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF DENVER   (United States)

^c PEPPERDINE UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Apoptosis; Caspase; Cerebellar granule neuron; Dynamin GTPase; Mitochondrial fusion; Optic atrophy type 1 (OPA1)

Indexed keywords

CASPASE 3; CASPASE 8; CYTOCHROME C; DIGITONIN; GUANOSINE TRIPHOSPHATASE; OPA1 ENZYME; POTASSIUM; PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; BRAIN NERVE CELL; CELL FUSION; CEREBELLUM; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVATION; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL DEGENERATION; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECRETION; RAT;

ANIMALS; APOPTOSIS; BRAIN; CASPASE 3; CASPASE 8; CASPASES; CELLS, CULTURED; CEREBELLUM; CYTOCHROMES C; DIGITONIN; GTP PHOSPHOHYDROLASES; HUMANS; MITOCHONDRIA; NEUROBLASTOMA; NEURONS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; STAUROSPORINE;

RATTUS;

EID: 58149314033     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.081     Document Type: Article

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