Peptide mapping of therapeutic monoclonal antibodies: Improvements for increased speed and fewer artifacts

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 3, 2009, Pages 230-236

  Dick Jr , Lawrence W ^a   Mahon, David ^a   Qiu, Difei ^a   Cheng, Kuang Chuan ^a  

^a MEDAREX INC   (United States)

Author keywords

Deamidation; Peptide mapping; Sample preparation; Trypsin digestion

Indexed keywords

A STABILITIES; DEAMIDATION; MAPPING METHODS; OPTIMIZATION SCHEMES; PEPTIDE MAPPING; PRODUCT IDENTITIES; REAL SAMPLES; SAMPLE PREPARATION; SOLVENT SELECTIONS; THERAPEUTIC MONOCLONAL ANTIBODIES; TIME CONSUMING; TRYPSIN DIGESTION;

ANTIBODIES; CONFORMAL MAPPING; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE;

AMINES;

MONOCLONAL ANTIBODY; TRYPSIN; UREA;

ARTICLE; ARTIFACT REDUCTION; CONTROLLED STUDY; DENATURATION; DIGESTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PEPTIDE MAPPING; PH MEASUREMENT; PRIORITY JOURNAL; REDUCTION; TEMPERATURE; VELOCITY;

ANTIBODIES, MONOCLONAL; ARTIFACTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEAMINATION; HUMANS; HYDROGEN-ION CONCENTRATION; PEPTIDE MAPPING; PROTEIN DENATURATION; REDUCING AGENTS; SOLVENTS; TEMPERATURE; TIME FACTORS; TRYPSIN; UREA;

EID: 58149314023     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.12.009     Document Type: Article

References (30)

1. Aires da Silva F., Corte-Real S., and Goncalves J. Biodrugs 22 (2008) 301
2. Bongers J., Cummings J., Ebert M., Federici M., Gledhill L., Gulati D., Hilliard G., Jones B., Lee K., Mozdzanowski J., Naimoli M., and Burman S. J. Pharm. Biomed. Anal. 21 (2000) 1099
3. Kleeman G., Beierle J., Nichols A., Dillon T., Pipes G., and Bondarenko P. Anal. Chem. 80 (2008) 2001
4. Huhmer A., Aced G., Perkins M., Gursoy R., Jois D., Larive C., Siahaan T., and Schoneich C. Anal. Chem. 69 (1997) 29R
5. Roberts G., Johnson W., Burman S., Anumula K., and Carr S. Anal. Chem. 67 (1995) 3613
6. Wang L., Amphlett G., Blattler W., Lambert J., and Zhang W. Protein Sci. 14 (2005) 2436
7. Wang L., Amphlett G., Lambert J., Blattler W., and Zhang W. Pharm. Res. 22 (2005) 1338
8. Kannan K., Mulkerrin M., Zhang M., Gray R., Steinharter T., Sewerin K., Baffi R., Harris R., and Karunatilake C. J. Pharm. Biomed. Anal. 16 (1997) 631
9. Hirayama K., Yuji R., Yamada N., Kato K., Arata Y., and Shimada I. Anal. Chem. 70 (1998) 2718
10. Fernandez L., Kalume D., Calvo L., Mallo M., Vallin A., and Roepstorff P. J. Chromatogr. B 752 (2001) 247
11. Griffiths S., and Cooney C. J. Chromatogr. A 942 (2002) 133
12. Liu H., Gaza-Bulseco G., and Sun J. J. Chromatogr. B 837 (2006) 35
13. Harris R., Kabakoff B., Macchia F., Shen F., Kwong M., Andya J., Shire S., Bjork N., Totpal K., and Chen A. J. Chromatogr. B 752 (2001) 233
14. Xiao G., and Bondarenko P. J. Pharm. Biomed. Anal. 47 (2008) 23
15. Lewis D., Guzzetta A., Hancock W., and Costello M. Anal. Chem. 66 (1994) 585
16. Dick Jr. L., Kim C., Qiu D., and Cheng K. Biotechnol. Bioeng. 97 (2006) 544
17. Dick Jr. L., Qiu D., Mahon D., Adamo M., and Cheng K. Biotechnol. Bioeng. 100 (2008) 1132
18. Wagner-Rousset E., Bednarczyk A., Bussat M., Colas O., Corvaia N., Schaeffer C., Van Dorsselaer A., and Beck A. J. Chromatogr. B 872 (2008) 23
19. Beck A., Bussat M., Zorn N., Robillard V., Klinguer-Hamour C., Chenu S., Goetsch L., Corvaia N., Van Dorsselaer A., and Haeuw J. J. Chromatogr. B 819 (2005) 203
20. Schaefer H., Chamrad D., Marcus K., Reidegeld K., Bluggel M., and Meyer H. Proteomics 5 (2005) 846
21. Lippincott J., and Apostol I. Anal. Biochem. 267 (1999) 57
22. Lundell N., and Schreitmuller T. Anal. Biochem. 266 (1999) 31
23. Chelius D., Xiao G., Nichols A., Vizel A., He B., Dillon T., Rehder D., Pipes G., Kraft E., Oroska A., Treuheit M., and Bondarenko P. J. Pharm. Biomed. Anal. 47 (2008) 285
24. Tous G., Wei Z., Feng J., Bowen S., Smith J., Strouse R., McGeehan P., Casas-Finet J., and Schenerman M. Anal. Chem. 77 (2005) 2675
25. Wei Z., Feng J., Lin H., Sombabu M., Bishop E., Tous G., Casas-Finet J., Hakki F., Strouse R., and Schenerman M. Anal. Chem. 79 (2007) 2797
26. McCarthy J., Hopwood F., Oxley D., Laver M., Castagna A., Righettti P., Williams K., and Herbert B. J. Proteome Res. 2 (2003) 239
27. Stark G. Biochemistry 4 (1965) 1030
28. Chelius D., Rehder D., and Bondarenko P. Anal. Chem. 77 (2005) 6004
29. Lill J., Ingle E., Liu P., Pham V., and Sandoval W. Mass Spectrom. Rev. 26 (2007) 657
30. Tran J., and Doucette A. J. Am. Soc. Mass Spectrom. 17 (2006) 652