Automated tryptic digestion procedure for HPLC/MS/MS peptide mapping of immunoglobulin gamma antibodies in pharmaceutics

Journal of Pharmaceutical and Biomedical Analysis

Volumn 47, Issue 2, 2008, Pages 285-294

  Chelius, Dirk ^a   Xiao, Gang ^a   Nichols, Andrew C ^a   Vizel, Alona ^a   He, Bing ^a   Dillon, Thomas M ^a   Rehder, Douglas S ^b   Pipes, Gary D ^a   Kraft, Edmund ^c   Oroska, Asha ^d   Treuheit, Michael J ^a   Bondarenko, Pavel V ^a  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

^c Tecan US   (United States)

^d Orochem Technologies Inc   (United States)

Author keywords

Automated proteolytic digestion; Immunoglobulin gamma antibody; Liquid handling system; Quantitative peptide mapping; Reversed phase HPLC MS MS

Indexed keywords

BUFFER; GUANIDINE; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN G2; TRYPSIN;

ALKYLATION; ANTIBODY DETECTION; ARTICLE; AUTOMATION; ENZYMATIC DEGRADATION; HIGH THROUGHPUT SCREENING; INTERMETHOD COMPARISON; LIQUID; MANUAL LABOR; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEOMICS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; TUBE;

ANTIBODIES; AUTOMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMMUNOGLOBULIN G; PEPTIDE MAPPING; PHARMACEUTICAL PREPARATIONS; TANDEM MASS SPECTROMETRY; TRYPSIN;

EID: 42749088930     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.01.018     Document Type: Article

References (24)

1. Shevchenko A.A., Jensen O.N., Podtelejnikov A.V., Sagliocco F., Wilm M., Vorm O., Mortensen P., Shevchenko A., Boucherie H., and Mann M. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 14440-14445
2. Henzel W.J., Billeci T.M., Stults J.T., Wong S.C., Grimley C., and Watanabe C. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 5011-5015
3. Houthaeve T., Gausepohl H., Mann M., and Ashman K. FEBS Lett. 376 (1995) 91-94
4. Houthaeve T., Gausepohl H., Ashman K., Nillson T., and Mann M. J. Protein Chem. 16 (1997) 343-348
5. Yokono T., Mineki R., Taka H., Kotaniguchi H., and Murayama K. J. Biomol. Tech. 14 (2003) 191-196
6. Steenvoorde R.J.J.M., Isaac I.S., Miller D.E., Woolsey R., Zhang H., Plumley F.G., Martinson T., and Quilici D. Proceedings of the 52nd ASMS Conference. Nashville, TN (2004)
7. Honegger A., and Pluckthun A. J. Mol. Biol. 309 (2001) 657-670
8. Oliner J., Min H., Leal J., Yu D., Rao S., You E., Tang X., Kim H., Meyer S., Han S.J., Hawkins N., Rosenfeld R., Davy E., Graham K., Jacobsen F., Stevenson S., Ho J., Chen Q., Hartmann T., Michaels M., Kelley M., Li L., Sitney K., Martin F., Sun J.R., Zhang N., Lu J., Estrada J., Kumar R., Coxon A., Kaufman S., Pretorius J., Scully S., Cattley R., Payton M., Coats S., Nguyen L., Desilva B., Ndifor A., Hayward I., Radinsky R., Boone T.C., and Kendall R. Cancer Cell 6 (2004) 507-516
9. Lewis D.A., Guzzetta A.W., Hancock W.S., and Costello M. Anal. Chem. 66 (1994) 585-595
10. Bongers J., Cummings J.J., Ebert M.B., Federici M.M., Gledhill L., Gulati D., Hilliard G.M., Jones B.H., Lee K.R., Mozdzanowski J., Naimoli M., and Burman S. J. Pharm. Biomed. Anal. 21 (2000) 1099-1128
11. Huang L., Lu J., Wroblewski V.J., Beals J.M., and Riggin R.M. Anal. Chem. 77 (2005) 1432-1439
12. Kannan K., Mulkerrin M.G., Zhang M., Gray R., Steinharter T., Sewerin K., Baffi R., Harris R.J., and Karunatilake C. J. Pharm. Biomed. Anal. 16 (1997) 631-640
13. Rehder D.S., Dillon T.M., Pipes G.D., and Bondarenko P.V. J. Chromatogr. A 1102 (2006) 164-175
14. Liu H., Gaza-Bulseco G., and Sun J. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 837 (2006) 35-43
15. Hale J.E., Butler J.P., Gelfanova V., You J.-S., and Knierman M.D. Anal. Biochem. 333 (2004) 174-181
16. Washburn M.P., Wolters D., and Yates III J.R. Nat. Biotechnol. 19 (2001) 242-247
17. Chelius D., Rehder D.S., and Bondarenko P.V. Anal. Chem. 77 (2005) 6004-6011
18. Zhang Z. Anal. Chem. 76 (2004) 3908-3922
19. Zhang Z. Anal. Chem. 76 (2004) 6374-6383
20. Chelius D., Jing K., Lueras A., Rehder D.S., Dillon T.M., Vizel A., Rajan R.S., Li T., Treuheit M.J., and Bondarenko P.V. Anal. Chem. 78 (2006) 2370-2376
21. Bondarenko P.V., Chelius D., and Shaler T.A. Anal. Chem. 74 (2002) 4741-4749
22. Chelius D., and Bondarenko P.V. J. Proteome Res. 1 (2002) 317-323
23. Berg M., Parbel A., Pettersen H., Fenyo D., and Bjorkesten L. Rapid Commun. Mass Spectrom. 20 (2006) 1558-1562
24. Berg M., Parbel A., Pettersen H., Fenyo D., and Bjorkesten L. J. Exp. Bot. 57 (2006) 1509-1514