Nuclear translocation of active AKT is required for erythroid differentiation in erythropoietin treated K562 erythroleukemia cells

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 3, 2009, Pages 570-577

  Missiroli, Silvia ^a   Etro, Daniela ^a   Buontempo, Francesca ^a   Ye, Keqiang ^b   Capitani, Silvano ^a   Neri, Luca Maria ^a  

^a Signal Transduction Unit   (Italy)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Erythroid differentiation; Erythropoietin; Nucleus; PI3K Akt; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AKT INHIBITOR IX; AKT INHIBITOR VI; AKT INHIBITOR VII; AKT INHIBITOR VIII; ERYTHROPOIETIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; SERINE 473; SERINE DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL ACTIVATION; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL FREE SYSTEM; CELL NUCLEUS; CELL STIMULATION; CELL STRAIN K 562; COMPARATIVE STUDY; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INTRANUCLEAR SPACE; MOLECULE; RNA SEQUENCE; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANDROSTADIENES; CELL DIFFERENTIATION; CELL LINEAGE; CELL NUCLEUS; CHROMONES; ERYTHROCYTES; ERYTHROPOIETIN; HUMANS; K562 CELLS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 58149305491     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.07.002     Document Type: Article

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