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Volumn 155, Issue 2, 2009, Pages 257-265

Spontaneous and cytokine induced expression and activity of matrix metalloproteinases in human colonic epithelium

Author keywords

Crohn's disease; Cytokines; Intestinal epithelial cells; MMP; Ulcerative colitis

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; ILOMASTAT; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; NEUTROPHIL COLLAGENASE; STROMELYSIN; STROMELYSIN 3; TUMOR NECROSIS FACTOR ALPHA;

EID: 58149291786     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03836.x     Document Type: Article
Times cited : (54)

References (44)
  • 1
  • 2
    • 0036288520 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease
    • Brynskov J, Foegh P, Pedersen G et al. Tumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease. Gut 2002 51 : 37 43.
    • (2002) Gut , vol.51 , pp. 37-43
    • Brynskov, J.1    Foegh, P.2    Pedersen, G.3
  • 3
    • 0034075936 scopus 로고    scopus 로고
    • Increased production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 by inflamed mucosa in inflammatory bowel disease
    • Louis E, Ribbens C, Godon A et al. Increased production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 by inflamed mucosa in inflammatory bowel disease. Clin Exp Immunol 2000 120 : 241 6.
    • (2000) Clin Exp Immunol , vol.120 , pp. 241-6
    • Louis, E.1    Ribbens, C.2    Godon, A.3
  • 4
    • 0033916643 scopus 로고    scopus 로고
    • Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease
    • Heuschkel RB, MacDonald TT, Monteleone G, Bajaj-Elliott M, Smith JA, Pender SL. Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease. Gut 2000 47 : 57 62.
    • (2000) Gut , vol.47 , pp. 57-62
    • Heuschkel, R.B.1    MacDonald, T.T.2    Monteleone, G.3    Bajaj-Elliott, M.4    Smith, J.A.5    Pender, S.L.6
  • 5
    • 0032880168 scopus 로고    scopus 로고
    • Matrix metalloproteinase levels are elevated in inflammatory bowel disease
    • Baugh MD, Perry MJ, Hollander AP et al. Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology 1999 117 : 814 22.
    • (1999) Gastroenterology , vol.117 , pp. 814-22
    • Baugh, M.D.1    Perry, M.J.2    Hollander, A.P.3
  • 6
    • 0033933804 scopus 로고    scopus 로고
    • Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease
    • von Lampe B, Barthel B, Coupland SE, Riecken EO, Rosewicz S. Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 2000 47 : 63 73.
    • (2000) Gut , vol.47 , pp. 63-73
    • Von Lampe, B.1    Barthel, B.2    Coupland, S.E.3    Riecken, E.O.4    Rosewicz, S.5
  • 7
    • 33748455465 scopus 로고    scopus 로고
    • Matrix metalloproteinases as profibrotic factors in terminal ileum in Crohn's disease
    • Warnaar N, Hofker HS, Maathuis MH et al. Matrix metalloproteinases as profibrotic factors in terminal ileum in Crohn's disease. Inflamm Bowel Dis 2006 12 : 863 9.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 863-9
    • Warnaar, N.1    Hofker, H.S.2    Maathuis, M.H.3
  • 8
    • 0034856382 scopus 로고    scopus 로고
    • Vascular smooth muscle cells and pericytes express MMP-1, MMP-9, TIMP-1 and type I procollagen in inflammatory bowel disease
    • Arihiro S, Ohtani H, Hiwatashi N, Torii A, Sorsa T, Nagura H. Vascular smooth muscle cells and pericytes express MMP-1, MMP-9, TIMP-1 and type I procollagen in inflammatory bowel disease. Histopathology 2001 39 : 50 9.
    • (2001) Histopathology , vol.39 , pp. 50-9
    • Arihiro, S.1    Ohtani, H.2    Hiwatashi, N.3    Torii, A.4    Sorsa, T.5    Nagura, H.6
  • 9
    • 0036785258 scopus 로고    scopus 로고
    • Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: Analysis by gene array and in situ hybridisation
    • Salmela MT, MacDonald TT, Black D et al. Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. Gut 2002 51 : 540 7.
    • (2002) Gut , vol.51 , pp. 540-7
    • Salmela, M.T.1    MacDonald, T.T.2    Black, D.3
  • 10
    • 33748477283 scopus 로고    scopus 로고
    • Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: Contrasting role of gelatinases in the pathogenesis of colitis
    • Garg P, Rojas M, Ravi A et al. Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis. J Immunol 2006 177 : 4103 12.
    • (2006) J Immunol , vol.177 , pp. 4103-12
    • Garg, P.1    Rojas, M.2    Ravi, A.3
  • 11
    • 0032063661 scopus 로고    scopus 로고
    • Proteolytic enzymes in inflammatory bowel disease
    • MacDonald TT, Pender SL. Proteolytic enzymes in inflammatory bowel disease. Inflamm Bowel Dis 1998 4 : 157 64.
    • (1998) Inflamm Bowel Dis , vol.4 , pp. 157-64
    • MacDonald, T.T.1    Pender, S.L.2
  • 13
    • 0030740249 scopus 로고    scopus 로고
    • Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds
    • Vaalamo M, Mattila L, Johansson N et al. Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds. J Invest Dermatol 1997 109 : 96 101.
    • (1997) J Invest Dermatol , vol.109 , pp. 96-101
    • Vaalamo, M.1    Mattila, L.2    Johansson, N.3
  • 14
    • 0037229533 scopus 로고    scopus 로고
    • Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis
    • Medina C, Videla S, Radomski A et al. Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis. Am J Physiol Gastrointest Liver Physiol 2003 284 : G116 G122.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Medina, C.1    Videla, S.2    Radomski, A.3
  • 15
    • 6044263423 scopus 로고    scopus 로고
    • An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice
    • Naito Y, Takagi T, Kuroda M et al. An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice. Inflamm Res 2004 53 : 462 8.
    • (2004) Inflamm Res , vol.53 , pp. 462-8
    • Naito, Y.1    Takagi, T.2    Kuroda, M.3
  • 16
    • 28844444159 scopus 로고    scopus 로고
    • Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: Central role of epithelial-derived MMP
    • Castaneda FE, Walia B, Vijay-Kumar M et al. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology 2005 129 : 1991 2008.
    • (2005) Gastroenterology , vol.129 , pp. 1991-2008
    • Castaneda, F.E.1    Walia, B.2    Vijay-Kumar, M.3
  • 17
    • 33745698756 scopus 로고    scopus 로고
    • Therapeutic implications of the specific inhibition of causative matrix metalloproteinases in experimental colitis induced by dextran sulphate sodium
    • Kobayashi K, Arimura Y, Goto A et al. Therapeutic implications of the specific inhibition of causative matrix metalloproteinases in experimental colitis induced by dextran sulphate sodium. J Pathol 2006 209 : 376 83.
    • (2006) J Pathol , vol.209 , pp. 376-83
    • Kobayashi, K.1    Arimura, Y.2    Goto, A.3
  • 18
    • 30044433929 scopus 로고    scopus 로고
    • Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells
    • Kruidenier L, MacDonald TT, Collins JE, Pender SL, Sanderson IR. Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Gastroenterology 2006 130 : 127 36.
    • (2006) Gastroenterology , vol.130 , pp. 127-36
    • Kruidenier, L.1    MacDonald, T.T.2    Collins, J.E.3    Pender, S.L.4    Sanderson, I.R.5
  • 19
    • 0031898338 scopus 로고    scopus 로고
    • Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations
    • Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P, Kere J, Saarialho-Kere U. Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations. Am J Pathol 1998 152 : 1005 14.
    • (1998) Am J Pathol , vol.152 , pp. 1005-14
    • Vaalamo, M.1    Karjalainen-Lindsberg, M.L.2    Puolakkainen, P.3    Kere, J.4    Saarialho-Kere, U.5
  • 20
    • 0345237913 scopus 로고    scopus 로고
    • Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease
    • McKaig BC, McWilliams D, Watson SA, Mahida YR. Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease. Am J Pathol 2003 162 : 1355 60.
    • (2003) Am J Pathol , vol.162 , pp. 1355-60
    • McKaig, B.C.1    McWilliams, D.2    Watson, S.A.3    Mahida, Y.R.4
  • 22
    • 2342417829 scopus 로고    scopus 로고
    • Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease
    • Kirkegaard T, Hansen A, Bruun E, Brynskov J. Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease. Gut 2004 53 : 701 9.
    • (2004) Gut , vol.53 , pp. 701-9
    • Kirkegaard, T.1    Hansen, A.2    Bruun, E.3    Brynskov, J.4
  • 23
    • 0038529391 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis
    • Matsuno K, Adachi Y, Yamamoto H et al. The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis. J Gastroenterol 2003 38 : 348 54.
    • (2003) J Gastroenterol , vol.38 , pp. 348-54
    • Matsuno, K.1    Adachi, Y.2    Yamamoto, H.3
  • 24
    • 33846413555 scopus 로고    scopus 로고
    • Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies
    • Pirila E, Korpi JT, Korkiamaki T et al. Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies. Wound Repair Regen 2007 15 : 47 57.
    • (2007) Wound Repair Regen , vol.15 , pp. 47-57
    • Pirila, E.1    Korpi, J.T.2    Korkiamaki, T.3
  • 25
    • 0033740718 scopus 로고    scopus 로고
    • Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines
    • Rechardt O, Elomaa O, Vaalamo M et al. Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines. J Invest Dermatol 2000 115 : 778 87.
    • (2000) J Invest Dermatol , vol.115 , pp. 778-87
    • Rechardt, O.1    Elomaa, O.2    Vaalamo, M.3
  • 26
    • 0037295912 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva
    • Ejeil AL, Igondjo-Tchen S, Ghomrasseni S, Pellat B, Godeau G, Gogly B. Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva. J Periodontol 2003 74 : 188 95.
    • (2003) J Periodontol , vol.74 , pp. 188-95
    • Ejeil, A.L.1    Igondjo-Tchen, S.2    Ghomrasseni, S.3    Pellat, B.4    Godeau, G.5    Gogly, B.6
  • 27
    • 0033636735 scopus 로고    scopus 로고
    • The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis
    • Tarlton JF, Whiting CV, Tunmore D, Bregenholt S, Claesson MH, Bland PW. The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis. Am J Pathol 2000 157 : 1927 35.
    • (2000) Am J Pathol , vol.157 , pp. 1927-35
    • Tarlton, J.F.1    Whiting, C.V.2    Tunmore, D.3    Bregenholt, S.4    Claesson, M.H.5    Bland, P.W.6
  • 28
    • 0037303555 scopus 로고    scopus 로고
    • Superoxide production and expression of NAD(P)H oxidases by transformed and primary human colonic epithelial cells
    • Perner A, Andresen L, Pedersen G, Rask-Madsen J. Superoxide production and expression of NAD(P)H oxidases by transformed and primary human colonic epithelial cells. Gut 2003 52 : 231 6.
    • (2003) Gut , vol.52 , pp. 231-6
    • Perner, A.1    Andresen, L.2    Pedersen, G.3    Rask-Madsen, J.4
  • 29
    • 0346057808 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha converting enzyme (TACE) activity in human colonic epithelial cells
    • Kirkegaard T, Pedersen G, Saermark T, Brynskov J. Tumour necrosis factor-alpha converting enzyme (TACE) activity in human colonic epithelial cells. Clin Exp Immunol 2004 135 : 146 53.
    • (2004) Clin Exp Immunol , vol.135 , pp. 146-53
    • Kirkegaard, T.1    Pedersen, G.2    Saermark, T.3    Brynskov, J.4
  • 30
    • 22344440495 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium
    • Pedersen G, Andresen L, Matthiessen MW, Rask-Madsen J, Brynskov J. Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium. Clin Exp Immunol 2005 141 : 298 306.
    • (2005) Clin Exp Immunol , vol.141 , pp. 298-306
    • Pedersen, G.1    Andresen, L.2    Matthiessen, M.W.3    Rask-Madsen, J.4    Brynskov, J.5
  • 31
    • 0033851841 scopus 로고    scopus 로고
    • Comparative studies of the colonic in situ expression of intercellular adhesion molecules (ICAM-1, -2, and -3), beta2 integrins (LFA-1, Mac-1, and p150,95), and PECAM-1 in ulcerative colitis and Crohn's disease
    • Vainer B, Nielsen OH, Horn T. Comparative studies of the colonic in situ expression of intercellular adhesion molecules (ICAM-1, -2, and -3), beta2 integrins (LFA-1, Mac-1, and p150,95), and PECAM-1 in ulcerative colitis and Crohn's disease. Am J Surg Pathol 2000 24 : 1115 24.
    • (2000) Am J Surg Pathol , vol.24 , pp. 1115-24
    • Vainer, B.1    Nielsen, O.H.2    Horn, T.3
  • 32
    • 0033883458 scopus 로고    scopus 로고
    • A simple method to establish short-term cultures of normal human colonic epithelial cells from endoscopic biopsy specimens. Comparison of isolation methods, assessment of viability and metabolic activity
    • Pedersen G, Saermark T, Giese B, Hansen A, Drag B, Brynskov J. A simple method to establish short-term cultures of normal human colonic epithelial cells from endoscopic biopsy specimens. Comparison of isolation methods, assessment of viability and metabolic activity. Scand J Gastroenterol 2000 35 : 772 80.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 772-80
    • Pedersen, G.1    Saermark, T.2    Giese, B.3    Hansen, A.4    Drag, B.5    Brynskov, J.6
  • 33
    • 0034526855 scopus 로고    scopus 로고
    • Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion
    • Pedersen G, Saermark T, Bendtzen K, Brynskov J. Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion. Autoimmunity 2000 32 : 255 63.
    • (2000) Autoimmunity , vol.32 , pp. 255-63
    • Pedersen, G.1    Saermark, T.2    Bendtzen, K.3    Brynskov, J.4
  • 34
    • 8544273762 scopus 로고    scopus 로고
    • Metalloproteinases and transforming growth factor-alpha mediate substance P-induced mitogen-activated protein kinase activation and proliferation in human colonocytes
    • Koon HW, Zhao D, Na X, Moyer MP, Pothoulakis C. Metalloproteinases and transforming growth factor-alpha mediate substance P-induced mitogen-activated protein kinase activation and proliferation in human colonocytes. J Biol Chem 2004 279 : 45519 27.
    • (2004) J Biol Chem , vol.279 , pp. 45519-27
    • Koon, H.W.1    Zhao, D.2    Na, X.3    Moyer, M.P.4    Pothoulakis, C.5
  • 35
    • 36349003622 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-1 and tumor necrosis factor-alpha in ulcerative colitis
    • Wang YD, Mao JW. Expression of matrix metalloproteinase-1 and tumor necrosis factor-alpha in ulcerative colitis. World J Gastroenterol 2007 13 : 5926 32.
    • (2007) World J Gastroenterol , vol.13 , pp. 5926-32
    • Wang, Y.D.1    Mao, J.W.2
  • 37
    • 13144264134 scopus 로고    scopus 로고
    • Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis
    • Bister V, Salmela MT, Heikkila P et al. Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis. J Pediatr Gastroenterol Nutr 2005 40 : 60 6.
    • (2005) J Pediatr Gastroenterol Nutr , vol.40 , pp. 60-6
    • Bister, V.1    Salmela, M.T.2    Heikkila, P.3
  • 38
    • 17644393522 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds
    • Impola U, Jeskanen L, Ravanti L et al. Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds. Br J Dermatol 2005 152 : 720 6.
    • (2005) Br J Dermatol , vol.152 , pp. 720-6
    • Impola, U.1    Jeskanen, L.2    Ravanti, L.3
  • 39
    • 0036512085 scopus 로고    scopus 로고
    • Collagenase-2 (MMP-8) and collagenase-3 (MMP-13) in adult periodontitis: Molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue
    • Kiili M, Cox SW, Chen HY et al. Collagenase-2 (MMP-8) and collagenase-3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue. J Clin Periodontol 2002 29 : 224 32.
    • (2002) J Clin Periodontol , vol.29 , pp. 224-32
    • Kiili, M.1    Cox, S.W.2    Chen, H.Y.3
  • 40
    • 0037285748 scopus 로고    scopus 로고
    • Gelatinase a (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis)
    • Pirila E, Ramamurthy NS, Sorsa T, Salo T, Hietanen J, Maisi P. Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis). Dig Dis Sci 2003 48 : 93 8.
    • (2003) Dig Dis Sci , vol.48 , pp. 93-8
    • Pirila, E.1    Ramamurthy, N.S.2    Sorsa, T.3    Salo, T.4    Hietanen, J.5    Maisi, P.6
  • 41
    • 0033863450 scopus 로고    scopus 로고
    • Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis
    • Stallmach A, Chan CC, Ecker KW et al. Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis. Gut 2000 47 : 415 22.
    • (2000) Gut , vol.47 , pp. 415-22
    • Stallmach, A.1    Chan, C.C.2    Ecker, K.W.3
  • 42
    • 34247562290 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation
    • Garg P, Ravi A, Patel NR et al. Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. Gastroenterology 2007 132 : 1877 89.
    • (2007) Gastroenterology , vol.132 , pp. 1877-89
    • Garg, P.1    Ravi, A.2    Patel, N.R.3
  • 43
    • 0344953584 scopus 로고    scopus 로고
    • Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration
    • Pirila E, Sharabi A, Salo T et al. Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochem Biophys Res Commun 2003 303 : 1012 7.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 1012-7
    • Pirila, E.1    Sharabi, A.2    Salo, T.3
  • 44
    • 0032522666 scopus 로고    scopus 로고
    • A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production
    • Pender SL, Fell JM, Chamow SM, Ashkenazi A, MacDonald TT. A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production. J Immunol 1998 160 : 4098 103.
    • (1998) J Immunol , vol.160 , pp. 4098-103
    • Pender, S.L.1    Fell, J.M.2    Chamow, S.M.3    Ashkenazi, A.4    MacDonald, T.T.5


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