Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: Analysis by gene array and in situ hybridisation

Gut

Volumn 51, Issue 4, 2002, Pages 540-547

  Salmela, M T ^a   MacDonald, T T ^b   Black, D ^c,d   Irvine, B ^c   Zhuma, T ^c   Saarialho Kere, Ulpu ^a   Pender, S L F ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERLEUKIN 12; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 17; MATRIX METALLOPROTEINASE 19; MONOCLONAL ANTIBODY CD3; NEUTROPHIL COLLAGENASE; POKEWEED MITOGEN; STROMELYSIN; STROMELYSIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CELIAC DISEASE; CONTROLLED STUDY; ENTERITIS; EXPLANT; FETUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTESTINE INJURY; MUCOSAL IMMUNITY; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

COLLAGENASES; HUMANS; IN SITU HYBRIDIZATION; INTESTINE, SMALL; MATRIX METALLOPROTEINASE 10; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASES; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA; T-LYMPHOCYTES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TISSUE INHIBITOR OF METALLOPROTEINASES; UP-REGULATION;

EID: 0036785258     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.51.4.540     Document Type: Article

References (40)

1. Birkedal-Hansen H, Moore WG, Bodden MK, et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993;4:197-250.
2. Nagase H and Woessner JF. Matrix metalloproteinases. J Biol Chem 1999;274:21491-4.
3. de Coignac AB, Elson G, Delneste Y, et al. Cloning of MMP-26. A novel matrilysin-like proteinase. Eur J Biochem 2000;267:3323-9.
4. Brown PD. Matrix metalloproteinases in gastrointestinal cancer. Gut 1998;43:161-3.
5. Kahari VM, Saarialho-Kere U. Matrix metalloproteinases and their inhibitors in tumour growth and invasion. Ann Med 1999;31:34-45.
6. Bailey CJ, Hembry RM, Alexander A, et al. Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn's disease and normal intestine. J Clin Pathol 1994;47:113-16.
7. Saarialho-Kere UK, Vaalamo M, Puolakkainen P, et al. Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol 1996;148:519-26.
8. Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P, et al. Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations. Am J Pathol 1998;152:1005-14.
9. Baugh MD, Perry MJ, Hollander AP, et al. Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology 1999;117:814-22.
10. Heuschkel RB, MacDonald TT, Monteleone G, et al. Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease. Gut 2000;47:57-62.
11. Louis E, Ribbens C, Godon A, et al. Increased production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 by inflamed mucosa in inflammatory bowel disease. Clin Exp Immunol 2000;120:241-6.
12. Pender SL, Tickle SP, Docherty AJ, et al. A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol 1997;158:1582-90.
13. MacDonald TT, Spencer J. Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine. J Exp Med 1988;167:1341-9.
14. Lionetti P, Breese E, Braegger CP, et al. T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine. Gastroenterology 1993;105:373-81.
15. Lionetti P, Spencer J, Breese EJ, et al. Activation of mucosal V beta 3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B. Eur J Immunol 1993;23:664-8.
16. Pender SL, Lionetti P, Murch SH, et al. Proteolytic degradation of intestinal mucosal extracellular matrix after lamina propria T cell activation. Gut 1996;39:284-90.
17. Pender SL, Breese EJ, Gunther U, et al. Suppression of T cell-mediated injury in human gut by interleukin-10: role of matrix metalloproteinases. Gastroenterology 1998;115:573-83.
18. Pender SL, Fell JM, Chamow SM, et al. A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production. J Immunol 1998;160:4098-103.
19. Saarialho-Kere UK, Pentland AP, Birkedal-Hansen H, et al. Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest 1994;94:79-88.
20. Vaalamo M, Mattila L, Johansson N, et al. Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds. J Invest Dermatol 1997;109:96-101.
21. McDonnell S, Navre M, Coffey RJ, et al. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog 1991;4:527-33.
22. Airola K, Ahonen M, Johansson N, et al. Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression. J Histochem Cytochem 1998;46:437-47.
23. Lohi J, Lehti K, Westermarck J, et al. Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur J Biochem 1996;239:239-47.
24. Pender SL, Salmela MT, Monteleone G, et al. Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype. Am J Pathol 2000;157:1955-62.
25. Prosser IW, Stenmark KR, Suthar M, et al. Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization. Am J Pathol 1989;135:1073-88.
26. Saarialho-Kere UK, Chang ES, Welgus HG, et al. Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest 1992;90:1952-7.
27. Saarialho-Kere UK, Kovacs SO, Pentland AP, et al. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J Clin Invest 1993;92:2858-66.
28. Graham MF, Willey A, Zhu YN, et al. Corticosteroids repress the interleukin 1 beta-induced secretion of collagenase in human intestinal smooth muscle cells. Gastroenterology 1997;113:1924-9.
29. Vaalamo M, Weckroth M, Puolakkainen P, et al. Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds. Br J Dermatol 1996;135:52-9.
30. Chandler S, Cossins J, Lury J, et al. Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-alpha fusion protein. Biochem Biophys Res Commun 1996;228:421-9.
31. Murphy G, Cockett MI, Ward RV, et al. Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP). Brochem J 1991;277:277-9.
32. Wilson CL, Matrisian LM. Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int J Biochem Cell Biol 1996;28:123-36.
33. Seiki M. Membrane-type matrix metalloproteinases. APMIS 1999;107:137-43.
34. Johansson N, Vaalamo M, Grenman S, et al. Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas. Am J Pathol 1999;154:469-80.
35. von Lampe B, Barthel B, Coupland SE, et al. Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 2000;47:63-73.
36. Ravanti L, Hakkinen L, Larjava H, et al. Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase. J Biol Chem 1999;274:37292-300.
37. Apte SS, Olsen BR, Murphy G. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem 1995;270:14313-18.
38. Willmroth F, Peter HH, Conca W. A matrix metalloproteinase gene expressed in human T lymphocytes is identical with collagenase 3 from breast carcinomas. Immunobiology 1998;198:375-84.
39. Leppert D, Waubant E, Galardy R, et al. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol 1995;154:4379-89.
40. Lacraz S, Isler P, Vey E, et al. Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression. J Biol Chem 1994;269:22027-33.