Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease

American Journal of Pathology

Volumn 162, Issue 4, 2003, Pages 1355-1360

  McKaig, Brian C ^a,b   McWilliams, Daniel ^a   Watson, Sue A ^a   Mahida, Yashwant R ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b NEW CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; ISOPROTEIN; MATRIX METALLOPROTEINASE; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA2; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA3; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ARTICLE; CELL CULTURE; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; CROHN DISEASE; EXTRACELLULAR MATRIX; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; INTESTINAL FIBROSIS; INTESTINE CELL; INTESTINE MUCOSA; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN DETERMINATION; ULCERATIVE COLITIS;

EID: 0345237913     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63931-4     Document Type: Article

References (26)

1. McAlindon ME, Gray T, Galvin A, Sewell HF, Podolsky DK, Mahida YR: Differential lamina propria cell migration via basement membrane pores of inflammatory bowel disease mucosa. Gastroenterology 1998, 115:841-848
2. Graham MF: Pathogenesis of intestinal strictures in CD - an update. Inflamm Bowel Dis 1995, 1:220-227
3. Nagase H, Woessner Jr JF: Matrix metalloproteinases. J Biol Chem 1999, 274:21491-21494
4. Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP: Tissue inhibitors of metal loproteinases: structure, regulation and biological functions. Eur J Cell Biol 1997, 74:111-122
5. Brew K, Dinakarpandian D, Nagase H: Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 2000, 1477:267-283
6. Border WA, Noble NA: Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994, 331:1286-1292
7. Overall CM, Wrana JL, Sodek J: Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV coliagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem 1991, 266:14064-14071
8. Mahida YR, Beltinger J, Makh S, Goke M, Gray T, Podolsky DK, Hawkey CJ: Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol 1997, 273:G1341-G1348
9. Pender SL, Tickle SP, Docherty AJ, Howie D, Wathen NC, MacDonald TT: A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol 1997, 158:1582-1590
10. McKaig BC, Makh SS, Hawkey CJ, Podolsky DK, Mahida YR: Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-beta3. Am J Physiol 1999, 276:G1087-G1093
11. McKaig BC, Hughes K, Tighe PJ, Mahida YR: Differential expression of TGF-isoforms by normal and inflammatory bowel disease intestinal myofibroblasts. Am J Physiol 2002, 282:C172-C182
12. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB: Myofibroblasts. II. Intestinal subepithelial myofibroblasts. Am J Physiol 1999, 277:C183-C201
13. Moore R, Carlson S, Madara JL: Villus contraction aids repair of intestinal epithelium after injury. Am J Physiol 1989, 257:G274-G283
14. van Tol EA, Holt L, Li FL, Kong FM, Rippe R, Yamauchi M, Pucilowska J, Lund PK, Sartor RB: Bacterial cell wall polymers promote intestinal fibrosis by direct stimulation of myofibroblasts. Am J Physiol 1999, 277:G245-G255
15. Plateroti M, Rubin DC, Duluc I, Singh R, Foltzer-Jourdainne C, Freund J, Kedinger M: Subepithelial fibroblast cell lines from different levels of gut axis display regional characteristics. Am J Physiol 1998, 274: G945-G954
16. Ichiki Y, Smith E, LeRoy EC, Trojanowska M: Different effects of basic fibroblast growth factor and transforming growth factor-beta on the two platelet-derived growth factor receptors' expression in scleroderma and healthy human dermal fibroblasts. J Invest Dermatol 1995, 104:124-127
17. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saadi JI, West AB: Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 1999, 277:C1-C19
18. Shah M, Foreman DM, Ferguson MW: Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J Cell Sci 1995, 108:985-1002
19. Shah M, Foreman DM, Ferguson MW: Neutralising antibody to TGF-beta 1, 2 reduces cutaneous scarring in adult rodents. J Cell Sci 1994, 107:1137-1157
20. Bailey CJ, Hembry RM, Alexander A, Irving MH, Grant ME, Shuttleworth CA: Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn's disease and normal intestine. J Clin Pathol 1994, 47:113-116
21. Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P, Kere J, Saarialho-Kere U: Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations. Am J Pathol 1998, 152:1005-1014
22. Baugh MD, Perry MJ, Hollander AP, Davies DR, Cross SS, Lobo AJ, Taylor CJ, Evans GS: Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology 1999, 117:814-822
23. von Lampe B, Barthel B, Coupland SE, Riecken EO, Rosewicz S: Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 2000, 47:63-73
24. Heuschkel RB, MacDonald TT, Monteleone G, Bajaj-Elliott M, Smith JA, Pender SL: Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease. Gut 2000, 47: 57-62
25. Salmela MT, MacDonald TT, Black D, Irvine B, Zhuma T, Saarialho-Kere U, Pender SL: Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. Gut 2002, 51:540-547
26. Graham MF: Pathogenesis of intestinal strictures in Crohn's disease - an update. Inflamm Bowel Dis 1995, 1:220-227