Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 γ2-chain expression in murine inflammatory bowel disease (ulcerative colitis)

Digestive Diseases and Sciences

Volumn 48, Issue 1, 2003, Pages 93-98

  Pirilä, Emma ^a,d   Ramamurthy, Nungavarm S ^b   Sorsa, Timo ^a   Salo, Tuula ^c   Hietanen, Jarkko ^a   Maisi, Päivi ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF OULU   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Immunohistochemistry; Inflammatory bowel disease; Laminin 5; Matrix metalloproteinase

Indexed keywords

GELATINASE A; KALININ; NEUTROPHIL COLLAGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; ENTERITIS; EPITHELIUM CELL; HEMIDESMOSOME; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; INTESTINE CRYPT; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ULCERATIVE COLITIS;

ANIMALS; CELL ADHESION MOLECULES; COLITIS, ULCERATIVE; COLON; DEXTRAN SULFATE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 8; MICE;

EID: 0037285748     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021790532723     Document Type: Article

References (29)

1. Riddel RH: Pathology of idiopathic inflammatory bowel diseases. In Inflammatory Bowel Diseases. JB Kirseners, RG Shorter (eds). Philadelphia, Lea and Febiger, 1988, pp 329-350
2. Schuppan D, Hahn EG: MMPs in the gut: inflammation hits the matrix. Gut 47:12-14, 2000
3. James SP, Klapproth JM: Major pathways of mucosal immunity and inflammation: cell activation, cytokine production and the role of bacterial factors. Aliment Pharmacol Ther 10:1-9, 1996
4. Mahler M, Bristol IJ, Leiter EH, Workman AE, Birkenmeier EH, Elson CO, Sundberg JP: Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol 274:G544-G551, 1998
5. Baugh MD, Perry MJ, Hollander AP, Davies DR, Cross SS. Lobo AJ, Taylor CJ, Evans GS: Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology 117:814-822, 1999
6. Shapiro SD: Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Curr Opin Cell Biol 10:602-608, 1998
7. Colognato H, Yurchenco PD: Form and function: the laminin family of heterotrimers. Dev Dyn 218:213-234, 2000
8. Pirila E, Maisi P, Salo T, Koivunen E, Sorsa T: In vivo localization of gelatinases (MMP-2 and -9) by in situ zymography with a selective gelatinase inhibitor. Biochem Biophys Res Commun 287:766-774, 2001
9. Pirila E, Parikka M, Ramamurthy NS, Maisi P, McClain S, Kucine A, Tervahartiala T, Prikk K, Golub LM, Salo T, Sorsa T: Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: Effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain. Wound Repair Regen 10:38-51, 2002
10. Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V: Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277:225-228, 1997
11. Ray MC, Gately LE: Basement membrane zone. Clin Dermatol 14:321-330, 1996
12. Pirila E, Ramamurthy N, Maisi P, McClain S, Kucine A, Wahlgren J, Golub L, Salo T, Sorsa T: Wound healing in ovariectomized rats: effects of chemically modified tetracycline (CMT-8) and estrogen on matrix metalloproteinases-8, -13 and type I collagen expression. Curr Med Chem 8:281-294, 2001
13. Makela M, Larjava H, Pirila E, Maisi P, Salo T, Sorsa T, Uitto VJ: Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes. Exp Cell Res 251:67-78, 1999
14. Prikk K, Maisi P, Pirila E, Sepper R, Salo T, Wahlgren J, Sorsa T: In vivo collagenase-2 (MMP-8) expression by human bronchial epithelial cells and monocytes/macrophages in bronchiectasis. J Pathol 194:232-238, 2001
15. Tervahartiala T, Pirila E, Ceponis A, Maisi P, Salo T, Tuter G, Kallio P, Tornwall J, Srinivas R, Konttinen YT, Sorsa T: The in vivo expression of the collagenolytic matrix metalloproteinases (MMP-2, -8, -13, and -14) and matrilysin (MMP-7) in adult and localized juvenile periodontitis. J Dent Res 79:1969-1977, 2000
16. Huhtala P, Chow LT, Tryggvason K: Structure of the human type IV collagenase gene. J Biol Chem 265:11077-11082, 1990
17. Kallunki P, Sainio K, Eddy R, Byers M, Kallunki T, Sariola H, Beck K, Hirvonen H, Shows TB, Tryggvason K: A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment. J Cell Biol 119:679-693. 1992
18. Hasty KA, Pourmotabbed TF, Goldberg GI, Thompson JP, Spinella DG, Stevens RM, Mainardi CL: Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J Biol Chem 265:11421-11424, 1990
19. Westerlund U, Ingman T, Lukinmaa PL, Salo T, Kjeldsen L, Borregaard N, Tjaderhane L, Konttinen YT, Sorsa T: Human neutrophil gelatinase and associated lipocalin in adult and localized juvenile periodontitis. J Dent Res 75:1553-1563, 1996
20. Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K: Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 55:4132-4139, 1995
21. Hanemaaijer R, Sorsa T, Konttinen YT, Ding Y, Sutinen M, Visser H, van Hinsbergh VW, Helaakoski T, Kainulainen T, Ronka H, Tschesche H, Salo T: Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline. J Biol Chem 272:31504-31509, 1997
22. Bachmeier BE, Nerlich AG, Boukamp P, Lichtinghagen R, Tschesche H, Fritz H, Fink E: Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and -13 and of TIMP-1. Biol Chem 381:509-516, 2000
23. Sorsa T, Uitto VJ, Suomalainen K, Vauhkonen M, Lindy S: Comparison of interstitial collagenases from human gingiva, sulcular fluid and polymorphonuclear leukocytes. J Periodontal Res 23:386-393, 1988
24. Bachmeier BE, Boukamp P, Lichtinghagen R, Fusenig NE, Fink E: Matrix metalloproteinases-2,-3,-7,-9 and-10, but not MMP-11, are differentially expressed in normal, benign tumorigenic and malignant human keratinocyte cell lines. Biol Chem 381:497-507, 2000
25. Stallmach A, Chan CC, Ecker KW, Feifel G, Herbst H, Schuppan D, Zeitz M: Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis. Gut 47:415-422, 20O0
26. von Lampe B, Barthel B, Coupland SE, Riecken EO, Rosewicz S: Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 47:63-73, 2000
27. Tarlton JF, Whiting CV, Tunmore D, Bregenholt S, Reimann J, Claesson MH, Bland PW: The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis. Am J Pathol 157:1927-1935, 2000
28. Stetler-Stevenson WG, Krutzsch HC, Wacher MP, Margulies IM, Liotta LA: The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation, J Biol Chem 264:1353-1356, 1989
29. Leivo I, Tani T, Laitinen L, Bruns R, Kivilaakso E, Lehto VP, Burgeson RE, Virtanen I: Anchoring complex components laminin-5 and type VII collagen in intestine: association with migrating and differentiating enterocytes. J Histochem Cytochem 44:1267-1277, 1996