메뉴 건너뛰기




Volumn 38, Issue 10, 2008, Pages 2689-2696

NKT cell development in the absence of the autoimmune regulator gene (Aire)

Author keywords

Aire; NKT cell; T regulatory cells; Thymus; Tolerance

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CYTOKINE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR;

EID: 58149265393     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838553     Document Type: Article
Times cited : (11)

References (38)
  • 2
    • 25844526684 scopus 로고    scopus 로고
    • Central tolerance: Learning self-control in the thymus
    • Hogquist, K. A., Baldwin, T. A. and Jameson, S. C., Central tolerance: Learning self-control in the thymus. Nat. Rev. Immunol. 2005. 5: 772-782.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 772-782
    • Hogquist, K.A.1    Baldwin, T.A.2    Jameson, S.C.3
  • 3
    • 33646165128 scopus 로고    scopus 로고
    • A central role for central tolerance
    • Kyewski, B. and Klein, L., A central role for central tolerance. Annu. Rev. Immunol. 2006. 24: 571-606.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 6
    • 4544258485 scopus 로고    scopus 로고
    • Self-representation in the thymus: An extended view
    • Kyewski, B. and Derbinski, J., Self-representation in the thymus: an extended view. Nat. Rev. Immunol. 2004. 4: 688-698.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 7
    • 0033153064 scopus 로고    scopus 로고
    • In vivo T-lymphocyte tolerance in the absence of thymic clonal deletion mediated by hematopoietic cells
    • van Meerwijk, J. P. and MacDonald, H. R., In vivo T-lymphocyte tolerance in the absence of thymic clonal deletion mediated by hematopoietic cells. Blood 1999. 93: 3856-3862.
    • (1999) Blood , vol.93 , pp. 3856-3862
    • van Meerwijk, J.P.1    MacDonald, H.R.2
  • 8
    • 13544262691 scopus 로고    scopus 로고
    • Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
    • Kuroda, N., Mitani, T., Takeda, N., Ishimaru, N., Arakaki, R., Hayashi, Y., Bando, Y. et al., Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J. Immunol. 2005. 174: 1862-1870.
    • (2005) J. Immunol , vol.174 , pp. 1862-1870
    • Kuroda, N.1    Mitani, T.2    Takeda, N.3    Ishimaru, N.4    Arakaki, R.5    Hayashi, Y.6    Bando, Y.7
  • 9
    • 34447098797 scopus 로고    scopus 로고
    • Multistep pathogenesis of autoimmune disease
    • Goodnow, C. C., Multistep pathogenesis of autoimmune disease. Cell 2007. 130: 25-35.
    • (2007) Cell , vol.130 , pp. 25-35
    • Goodnow, C.C.1
  • 11
    • 33846203837 scopus 로고    scopus 로고
    • A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
    • Kekalainen, E., Tuovinen, H., Joensuu, J., Gylling, M., Franssila, R., Pontynen, N., Talvensaari, K. et al., A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J. Immunol. 2007. 178: 1208-1215.
    • (2007) J. Immunol , vol.178 , pp. 1208-1215
    • Kekalainen, E.1    Tuovinen, H.2    Joensuu, J.3    Gylling, M.4    Franssila, R.5    Pontynen, N.6    Talvensaari, K.7
  • 12
    • 34248570322 scopus 로고    scopus 로고
    • Foxp3 and Aire in thymus-generated Treg cells: A link in self-tolerance
    • Nomura, T. and Sakaguchi, S., Foxp3 and Aire in thymus-generated Treg cells: A link in self-tolerance. Nat. Immunol. 2007. 8: 333-334.
    • (2007) Nat. Immunol , vol.8 , pp. 333-334
    • Nomura, T.1    Sakaguchi, S.2
  • 13
    • 34248598295 scopus 로고    scopus 로고
    • Selection of Foxp3+regulatory T cells specific for self antigen expressed and presented by Aire+medullary thymic epithelial cells
    • Aschenbrenner, K., D'Cruz, L. M., Vollmann, E. H., Hinterberger, M., Emmerich, J., Swee, L. K., Rolink, A. and Klein, L., Selection of Foxp3+regulatory T cells specific for self antigen expressed and presented by Aire+medullary thymic epithelial cells. Nat. Immunol. 2007. 8: 351-358.
    • (2007) Nat. Immunol , vol.8 , pp. 351-358
    • Aschenbrenner, K.1    D'Cruz, L.M.2    Vollmann, E.H.3    Hinterberger, M.4    Emmerich, J.5    Swee, L.K.6    Rolink, A.7    Klein, L.8
  • 14
    • 17144374753 scopus 로고    scopus 로고
    • Toward an understanding of NKT cell biology: Progress and paradoxes
    • Kronenberg, M., Toward an understanding of NKT cell biology: progress and paradoxes. Annu. Rev. Immunol. 2005. 23: 877-900.
    • (2005) Annu. Rev. Immunol , vol.23 , pp. 877-900
    • Kronenberg, M.1
  • 16
    • 0037364854 scopus 로고    scopus 로고
    • Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
    • Wilson, S. B. and Delovitch, T. L., Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat. Rev. Immunol. 2003. 3: 211-222.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 211-222
    • Wilson, S.B.1    Delovitch, T.L.2
  • 17
    • 10044286529 scopus 로고    scopus 로고
    • Going both ways: Immune regulation via CD1d-dependent NKT cells
    • Godfrey, D. I. and Kronenberg, M., Going both ways: Immune regulation via CD1d-dependent NKT cells. J. Clin. Invest. 2004. 114: 1379-1388.
    • (2004) J. Clin. Invest , vol.114 , pp. 1379-1388
    • Godfrey, D.I.1    Kronenberg, M.2
  • 18
    • 34247577500 scopus 로고    scopus 로고
    • NKT cells: T lymphocytes with innate effector functions
    • Van Kaer, L., NKT cells: T lymphocytes with innate effector functions. Curr. Opin. Immunol. 2007. 19: 354-364.
    • (2007) Curr. Opin. Immunol , vol.19 , pp. 354-364
    • Van Kaer, L.1
  • 19
    • 34250849637 scopus 로고    scopus 로고
    • Control points in NKT-cell development
    • Godfrey, D. I. and Berzins, S. P., Control points in NKT-cell development. Nat. Rev. Immunol. 2007. 7: 505-518.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 505-518
    • Godfrey, D.I.1    Berzins, S.P.2
  • 20
    • 0033939699 scopus 로고    scopus 로고
    • RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
    • Heino, M., Peterson, P., Sillanpaa, N., Guerin, S., Wu, L., Anderson, G., Scott, H. S. et al., RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur. J. Immunol. 2000. 30: 1884-1893.
    • (2000) Eur. J. Immunol , vol.30 , pp. 1884-1893
    • Heino, M.1    Peterson, P.2    Sillanpaa, N.3    Guerin, S.4    Wu, L.5    Anderson, G.6    Scott, H.S.7
  • 21
    • 0038544169 scopus 로고    scopus 로고
    • NIK-dependent RelB activation defines a unique signaling pathway for the development of Valpha14i NKT Cells
    • Elewaut, D., Shaikh, R. B., Hammond, K. J., DeWinter, H., Leishman, A. J., Sidobre, S., Turovskaya, O. et al., NIK-dependent RelB activation defines a unique signaling pathway for the development of Valpha14i NKT Cells. J. Exp. Med. 2003. 197: 1623-1633.
    • (2003) J. Exp. Med , vol.197 , pp. 1623-1633
    • Elewaut, D.1    Shaikh, R.B.2    Hammond, K.J.3    DeWinter, H.4    Leishman, A.J.5    Sidobre, S.6    Turovskaya, O.7
  • 22
    • 0038544245 scopus 로고    scopus 로고
    • Differential requirement for Rel/nuclear factor {kappa}B family members in natural killer T cell development
    • Sivakumar, V., Hammond, K. J., Howells, N., Pfeffer, K. and Weih, F., Differential requirement for Rel/nuclear factor {kappa}B family members in natural killer T cell development. J. Exp. Med. 2003. 197: 1613-1621.
    • (2003) J. Exp. Med , vol.197 , pp. 1613-1621
    • Sivakumar, V.1    Hammond, K.J.2    Howells, N.3    Pfeffer, K.4    Weih, F.5
  • 24
    • 0034661974 scopus 로고    scopus 로고
    • Membrane lymphotoxin is required for the development of different subpopulations of NK T cells
    • Elewaut, D., Brossay, L., Santee, S. M., Naidenko, O. V., Burdin, N., De Winter, H., Matsuda, J. et al., Membrane lymphotoxin is required for the development of different subpopulations of NK T cells. J. Immunol. 2000. 165: 671-679.
    • (2000) J. Immunol , vol.165 , pp. 671-679
    • Elewaut, D.1    Brossay, L.2    Santee, S.M.3    Naidenko, O.V.4    Burdin, N.5    De Winter, H.6    Matsuda, J.7
  • 25
    • 38449096249 scopus 로고    scopus 로고
    • Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected
    • Venanzi, E. S., Gray, D. H., Benoist, C. and Mathis, D., Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected. J. Immunol. 2007. 179: 5693-5700.
    • (2007) J. Immunol , vol.179 , pp. 5693-5700
    • Venanzi, E.S.1    Gray, D.H.2    Benoist, C.3    Mathis, D.4
  • 26
    • 47949100152 scopus 로고    scopus 로고
    • Lt{beta}r signaling does not regulate Aire-dependent transcripts in medullary thymic epithelial cells
    • Martins, V. C., Boehm, T. and Bleul, C. C., Lt{beta}r signaling does not regulate Aire-dependent transcripts in medullary thymic epithelial cells. J. Immunol. 2008. 181: 400-407.
    • (2008) J. Immunol , vol.181 , pp. 400-407
    • Martins, V.C.1    Boehm, T.2    Bleul, C.C.3
  • 27
    • 45949094459 scopus 로고    scopus 로고
    • The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells
    • Seach, N., Ueno, T., Fletcher, A. L., Lowen, T., Mattesich, M., Engwerda, C. R., Scott, H. S. et al., The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells. J. Immunol. 2008. 180: 5384-5392.
    • (2008) J. Immunol , vol.180 , pp. 5384-5392
    • Seach, N.1    Ueno, T.2    Fletcher, A.L.3    Lowen, T.4    Mattesich, M.5    Engwerda, C.R.6    Scott, H.S.7
  • 28
    • 38049166146 scopus 로고    scopus 로고
    • Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations
    • Matangkasombut, P., Pichavant, M., Saez, D. E., Giliani, S., Mazzolari, E., Finocchi, A., Villa, A. et al., Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations. Blood 2008. 111: 271-274.
    • (2008) Blood , vol.111 , pp. 271-274
    • Matangkasombut, P.1    Pichavant, M.2    Saez, D.E.3    Giliani, S.4    Mazzolari, E.5    Finocchi, A.6    Villa, A.7
  • 30
    • 33744988740 scopus 로고    scopus 로고
    • The autoimmune regulator (Aire) controls iNKT cell development and maturation
    • Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R. et al., The autoimmune regulator (Aire) controls iNKT cell development and maturation. Nat. Med. 2006. 12: 624-626.
    • (2006) Nat. Med , vol.12 , pp. 624-626
    • Mi, Q.S.1    Deng, Z.B.2    Joshi, S.K.3    Wang, Z.Z.4    Zhou, L.5    Eckenrode, S.6    Joshi, R.7
  • 31
    • 33744988740 scopus 로고    scopus 로고
    • The autoimmune regulator (Aire) controls iNKT cell development and maturation
    • Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R. et al., The autoimmune regulator (Aire) controls iNKT cell development and maturation. Nat. Med. 2006. 12: 1100.
    • (2006) Nat. Med , vol.12 , pp. 1100
    • Mi, Q.S.1    Deng, Z.B.2    Joshi, S.K.3    Wang, Z.Z.4    Zhou, L.5    Eckenrode, S.6    Joshi, R.7
  • 32
    • 44849114330 scopus 로고    scopus 로고
    • A specific anti-aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery
    • Hubert, F. X., Kinkel, S. A., Webster, K. E., Cannon, P., Crewther, P. E., Proeitto, A. I., Wu, L. et al., A specific anti-aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery. J. Immunol. 2008. 180: 3824-3832.
    • (2008) J. Immunol , vol.180 , pp. 3824-3832
    • Hubert, F.X.1    Kinkel, S.A.2    Webster, K.E.3    Cannon, P.4    Crewther, P.E.5    Proeitto, A.I.6    Wu, L.7
  • 33
    • 20544459766 scopus 로고    scopus 로고
    • Working with NKT cells - pitfalls and practicalities
    • Berzins, S. P., Smyth, M. J. and Godfrey, D. I., Working with NKT cells - pitfalls and practicalities. Curr. Opin. Immunol. 2005. 17: 448-454.
    • (2005) Curr. Opin. Immunol , vol.17 , pp. 448-454
    • Berzins, S.P.1    Smyth, M.J.2    Godfrey, D.I.3
  • 35
    • 33748714526 scopus 로고    scopus 로고
    • Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma
    • Hassler, S., Ramsey, C., Karlsson, M. C., Larsson, D., Herrmann, B., Rozell, B., Backheden, M. et al., Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma. Blood 2006. 108: 1941-1948.
    • (2006) Blood , vol.108 , pp. 1941-1948
    • Hassler, S.1    Ramsey, C.2    Karlsson, M.C.3    Larsson, D.4    Herrmann, B.5    Rozell, B.6    Backheden, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.