메뉴 건너뛰기




Volumn 1790, Issue 2, 2009, Pages 110-118

Dynamics of gene expression during bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro

Author keywords

Differentiation; Embryonic stem cell; Extracellular matrix; Gene expression; Osteogenesis

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; OSTEOCALCIN; OSTEOPONTIN; SIALOPROTEIN; TRANSCRIPTION FACTOR OSTERIX; VASCULOTROPIN;

EID: 58149199688     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2008.10.004     Document Type: Article
Times cited : (85)

References (75)
  • 1
    • 0020535398 scopus 로고
    • Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture
    • Ecarot-Charrier B., Glorieux F.H., van der Rest M., and Pereira G. Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture. J. Cell Biol. 96 (1983) 639-643
    • (1983) J. Cell Biol. , vol.96 , pp. 639-643
    • Ecarot-Charrier, B.1    Glorieux, F.H.2    van der Rest, M.3    Pereira, G.4
  • 6
    • 0022569874 scopus 로고
    • Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations
    • Bellows C.G., Aubin J.E., Heersche J.N., and Antosz M.E. Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif. Tissue Int. 38 (1986) 143-154
    • (1986) Calcif. Tissue Int. , vol.38 , pp. 143-154
    • Bellows, C.G.1    Aubin, J.E.2    Heersche, J.N.3    Antosz, M.E.4
  • 7
    • 0035236997 scopus 로고    scopus 로고
    • Regulation of osteoblast formation and function
    • Aubin J.E. Regulation of osteoblast formation and function. Rev. Endocr. Metab. Disord. 2 (2001) 81-94
    • (2001) Rev. Endocr. Metab. Disord. , vol.2 , pp. 81-94
    • Aubin, J.E.1
  • 8
    • 0032323828 scopus 로고    scopus 로고
    • Advances in the osteoblast lineage
    • Aubin J.E. Advances in the osteoblast lineage. Biochem. Cell. Biol. 76 (1998) 899-910
    • (1998) Biochem. Cell. Biol. , vol.76 , pp. 899-910
    • Aubin, J.E.1
  • 9
    • 32944462790 scopus 로고    scopus 로고
    • Biology of osteogenic sarcoma
    • Wang L.L. Biology of osteogenic sarcoma. Cancer J. 11 (2005) 294-305
    • (2005) Cancer J. , vol.11 , pp. 294-305
    • Wang, L.L.1
  • 11
    • 9344256686 scopus 로고    scopus 로고
    • In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells
    • Bielby R.C., Boccaccini A.R., Polak J.M., and Buttery L.D. In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells. Tissue Eng. 10 (2004) 1518-1525
    • (2004) Tissue Eng. , vol.10 , pp. 1518-1525
    • Bielby, R.C.1    Boccaccini, A.R.2    Polak, J.M.3    Buttery, L.D.4
  • 12
    • 0038638343 scopus 로고    scopus 로고
    • In vitro osteogenic differentiation of human ES cells
    • Sottile V., Thomson A., and McWhir J. In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells 5 (2003) 149-155
    • (2003) Cloning Stem Cells , vol.5 , pp. 149-155
    • Sottile, V.1    Thomson, A.2    McWhir, J.3
  • 13
    • 0041396065 scopus 로고    scopus 로고
    • In vitro differentiation of embryonic stem cells into mineralized osteoblasts
    • zur Nieden N.I., Kempka G., and Ahr H.J. In vitro differentiation of embryonic stem cells into mineralized osteoblasts. Differentiation 71 (2003) 18-27
    • (2003) Differentiation , vol.71 , pp. 18-27
    • zur Nieden, N.I.1    Kempka, G.2    Ahr, H.J.3
  • 14
    • 33847607063 scopus 로고    scopus 로고
    • Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro
    • Karner E., Unger C., Sloan A.J., Ahrlund-Richter L., Sugars R.V., and Wendel M. Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro. Stem Cells Dev. 16 (2007) 39-52
    • (2007) Stem Cells Dev. , vol.16 , pp. 39-52
    • Karner, E.1    Unger, C.2    Sloan, A.J.3    Ahrlund-Richter, L.4    Sugars, R.V.5    Wendel, M.6
  • 16
    • 21644442456 scopus 로고    scopus 로고
    • Osteogenic differentiation within intact human embryoid bodies result in a marked increase in osteocalcin secretion after 12 days of in vitro culture, and formation of morphologically distinct nodule-like structures
    • Cao T., Heng B.C., Ye C.P., Liu H., Toh W.S., Robson P., Li P., Hong Y.H., and Stanton L.W. Osteogenic differentiation within intact human embryoid bodies result in a marked increase in osteocalcin secretion after 12 days of in vitro culture, and formation of morphologically distinct nodule-like structures. Tissue Cell 37 (2005) 325-334
    • (2005) Tissue Cell , vol.37 , pp. 325-334
    • Cao, T.1    Heng, B.C.2    Ye, C.P.3    Liu, H.4    Toh, W.S.5    Robson, P.6    Li, P.7    Hong, Y.H.8    Stanton, L.W.9
  • 17
    • 34447633522 scopus 로고    scopus 로고
    • Differentiation of osteoblasts from mouse embryonic stem cells without generation of embryoid body
    • Duplomb L., Dagouassat M., Jourdon P., and Heymann D. Differentiation of osteoblasts from mouse embryonic stem cells without generation of embryoid body. In Vitro Cell. Dev. Biol. 43 (2007) 21-24
    • (2007) In Vitro Cell. Dev. Biol. , vol.43 , pp. 21-24
    • Duplomb, L.1    Dagouassat, M.2    Jourdon, P.3    Heymann, D.4
  • 19
    • 32044447008 scopus 로고    scopus 로고
    • Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells
    • Ryoo H.M., Lee M.H., and Kim Y.J. Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells. Gene 366 (2006) 51-57
    • (2006) Gene , vol.366 , pp. 51-57
    • Ryoo, H.M.1    Lee, M.H.2    Kim, Y.J.3
  • 20
    • 14644429806 scopus 로고    scopus 로고
    • Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages
    • zur Nieden N.I., Kempka G., Rancourt D.E., and Ahr H.J. Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages. BMC Dev. Biol. 5 (2005) 1
    • (2005) BMC Dev. Biol. , vol.5 , pp. 1
    • zur Nieden, N.I.1    Kempka, G.2    Rancourt, D.E.3    Ahr, H.J.4
  • 21
    • 33847233594 scopus 로고    scopus 로고
    • Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation
    • zur Nieden N.I., Price F.D., Davis L.A., Everitt R.E., and Rancourt D.E. Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation. Mol. Endocrinol. 21 (2007) 674-685
    • (2007) Mol. Endocrinol. , vol.21 , pp. 674-685
    • zur Nieden, N.I.1    Price, F.D.2    Davis, L.A.3    Everitt, R.E.4    Rancourt, D.E.5
  • 22
    • 0030804095 scopus 로고    scopus 로고
    • Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells
    • Hanada K., Dennis J.E., and Caplan A.I. Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells. J. Bone Miner. Res. 12 (1997) 1606-1614
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 1606-1614
    • Hanada, K.1    Dennis, J.E.2    Caplan, A.I.3
  • 23
    • 33847006266 scopus 로고    scopus 로고
    • Similar pattern in cardiac differentiation of human embryonic stem cell lines, BG01V and ReliCellhES1, under low serum concentration supplemented with bone morphogenetic protein-2
    • Pal R., and Khanna A. Similar pattern in cardiac differentiation of human embryonic stem cell lines, BG01V and ReliCellhES1, under low serum concentration supplemented with bone morphogenetic protein-2. Differentiation 75 (2007) 112-122
    • (2007) Differentiation , vol.75 , pp. 112-122
    • Pal, R.1    Khanna, A.2
  • 25
    • 0034457236 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation
    • Deckers M.M., Karperien M., van der Bent C., Yamashita T., Papapoulos S.E., and Lowik C.W. Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation. Endocrinology 141 (2000) 1667-1674
    • (2000) Endocrinology , vol.141 , pp. 1667-1674
    • Deckers, M.M.1    Karperien, M.2    van der Bent, C.3    Yamashita, T.4    Papapoulos, S.E.5    Lowik, C.W.6
  • 26
    • 0025040819 scopus 로고
    • Promotion of calvarial cell osteogenesis by endothelial cells
    • Villanueva J.E., and Nimni M.E. Promotion of calvarial cell osteogenesis by endothelial cells. J. Bone Miner. Res. 5 (1990) 733-739
    • (1990) J. Bone Miner. Res. , vol.5 , pp. 733-739
    • Villanueva, J.E.1    Nimni, M.E.2
  • 29
    • 0032479281 scopus 로고    scopus 로고
    • Osteoadherin, a cell-binding keratan sulfate proteoglycan in bone, belongs to the family of leucine-rich repeat proteins of the extracellular matrix
    • Sommarin Y., Wendel M., Shen Z., Hellman U., and Heinegard D. Osteoadherin, a cell-binding keratan sulfate proteoglycan in bone, belongs to the family of leucine-rich repeat proteins of the extracellular matrix. J. Biol. Chem. 273 (1998) 16723-16729
    • (1998) J. Biol. Chem. , vol.273 , pp. 16723-16729
    • Sommarin, Y.1    Wendel, M.2    Shen, Z.3    Hellman, U.4    Heinegard, D.5
  • 31
    • 0029977717 scopus 로고    scopus 로고
    • Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins
    • Hunter G.K., Hauschka P.V., Poole A.R., Rosenberg L.C., and Goldberg H.A. Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins. Biochem. J. 317 Pt 1 (1996) 59-64
    • (1996) Biochem. J. , vol.317 , Issue.PART 1 , pp. 59-64
    • Hunter, G.K.1    Hauschka, P.V.2    Poole, A.R.3    Rosenberg, L.C.4    Goldberg, H.A.5
  • 32
    • 22144468433 scopus 로고    scopus 로고
    • Derivation of multipotent mesenchymal precursors from human embryonic stem cells
    • Barberi T., Willis L.M., Socci N.D., and Studer L. Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS Med. 2 (2005) e161
    • (2005) PLoS Med. , vol.2
    • Barberi, T.1    Willis, L.M.2    Socci, N.D.3    Studer, L.4
  • 35
    • 4444291075 scopus 로고    scopus 로고
    • Ascorbic acid responsive genes during neuronal differentiation of embryonic stem cells
    • Shin D.M., Ahn J.I., Lee K.H., Lee Y.S., and Lee Y.S. Ascorbic acid responsive genes during neuronal differentiation of embryonic stem cells. NeuroReport 15 (2004) 1959-1963
    • (2004) NeuroReport , vol.15 , pp. 1959-1963
    • Shin, D.M.1    Ahn, J.I.2    Lee, K.H.3    Lee, Y.S.4    Lee, Y.S.5
  • 36
    • 33745128352 scopus 로고    scopus 로고
    • Dexamethasone facilitates erythropoiesis in murine embryonic stem cells differentiating into hematopoietic cells in vitro
    • Srivastava A.S., Kaushal S., Mishra R., Lane T.A., and Carrier E. Dexamethasone facilitates erythropoiesis in murine embryonic stem cells differentiating into hematopoietic cells in vitro. Biochem. Biophys. Res. Commun. 346 (2006) 508-516
    • (2006) Biochem. Biophys. Res. Commun. , vol.346 , pp. 508-516
    • Srivastava, A.S.1    Kaushal, S.2    Mishra, R.3    Lane, T.A.4    Carrier, E.5
  • 37
    • 33645751438 scopus 로고    scopus 로고
    • Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features
    • Darr H., Mayshar Y., and Benvenisty N. Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features. Development 133 (2006) 1193-1201
    • (2006) Development , vol.133 , pp. 1193-1201
    • Darr, H.1    Mayshar, Y.2    Benvenisty, N.3
  • 39
    • 39549112087 scopus 로고    scopus 로고
    • Forced expression of Sox2 or Nanog in human bone marrow derived mesenchymal stem cells maintains their expansion and differentiation capabilities
    • Go M.J., Takenaka C., and Ohgushi H. Forced expression of Sox2 or Nanog in human bone marrow derived mesenchymal stem cells maintains their expansion and differentiation capabilities. Exp. Cell Res. 314 (2008) 1147-1154
    • (2008) Exp. Cell Res. , vol.314 , pp. 1147-1154
    • Go, M.J.1    Takenaka, C.2    Ohgushi, H.3
  • 40
    • 0346250853 scopus 로고    scopus 로고
    • Sustained in vitro expansion of bone progenitors is cell density dependent
    • Purpura K.A., Aubin J.E., and Zandstra P.W. Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells 22 (2004) 39-50
    • (2004) Stem Cells , vol.22 , pp. 39-50
    • Purpura, K.A.1    Aubin, J.E.2    Zandstra, P.W.3
  • 41
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
    • Reubinoff B.E., Pera M.F., Fong C.Y., Trounson A., and Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18 (2000) 399-404
    • (2000) Nat. Biotechnol. , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 42
    • 0042204967 scopus 로고    scopus 로고
    • Transcriptional mechanisms in osteoblast differentiation and bone formation
    • Nakashima K., and de Crombrugghe B. Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet. 19 (2003) 458-466
    • (2003) Trends Genet. , vol.19 , pp. 458-466
    • Nakashima, K.1    de Crombrugghe, B.2
  • 43
    • 33748603189 scopus 로고    scopus 로고
    • Differential regulation of osteoadherin (OSAD) by TGF-beta1 and BMP-2
    • Rehn A.P., Chalk A.M., and Wendel M. Differential regulation of osteoadherin (OSAD) by TGF-beta1 and BMP-2. Biochem. Biophys. Res. Commun. 349 (2006) 1057-1064
    • (2006) Biochem. Biophys. Res. Commun. , vol.349 , pp. 1057-1064
    • Rehn, A.P.1    Chalk, A.M.2    Wendel, M.3
  • 44
    • 0032482223 scopus 로고    scopus 로고
    • Bone matrix proteins: isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (osteoadherin) from bovine bone
    • Wendel M., Sommarin Y., and Heinegard D. Bone matrix proteins: isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (osteoadherin) from bovine bone. J. Cell Biol. 141 (1998) 839-847
    • (1998) J. Cell Biol. , vol.141 , pp. 839-847
    • Wendel, M.1    Sommarin, Y.2    Heinegard, D.3
  • 45
    • 0043211869 scopus 로고    scopus 로고
    • Ultrastructural distribution of osteoadherin in rat bone shows a pattern similar to that of bone sialoprotein
    • Ramstad V.E., Franzen A., Heinegard D., Wendel M., and Reinholt F.P. Ultrastructural distribution of osteoadherin in rat bone shows a pattern similar to that of bone sialoprotein. Calcif. Tissue Int. 72 (2003) 57-64
    • (2003) Calcif. Tissue Int. , vol.72 , pp. 57-64
    • Ramstad, V.E.1    Franzen, A.2    Heinegard, D.3    Wendel, M.4    Reinholt, F.P.5
  • 46
    • 55249114587 scopus 로고    scopus 로고
    • Osteoadherin (OSAD) is up-regulated by mature osteoblasts and enhances their in vitro differentiation and mineralisation
    • Rehn A.P., Cerny R., Sugars R.V., Kaukua N., and Wendel M. Osteoadherin (OSAD) is up-regulated by mature osteoblasts and enhances their in vitro differentiation and mineralisation. Calcif. Tissue Int. 82 (2008) 454-464
    • (2008) Calcif. Tissue Int. , vol.82 , pp. 454-464
    • Rehn, A.P.1    Cerny, R.2    Sugars, R.V.3    Kaukua, N.4    Wendel, M.5
  • 47
    • 0028072277 scopus 로고
    • Simultaneous detection of multiple bone-related mRNAs and protein expression during osteoblast differentiation: polymerase chain reaction and immunocytochemical studies at the single cell level
    • Liu F., Malaval L., Gupta A.K., and Aubin J.E. Simultaneous detection of multiple bone-related mRNAs and protein expression during osteoblast differentiation: polymerase chain reaction and immunocytochemical studies at the single cell level. Dev. Biol. 166 (1994) 220-234
    • (1994) Dev. Biol. , vol.166 , pp. 220-234
    • Liu, F.1    Malaval, L.2    Gupta, A.K.3    Aubin, J.E.4
  • 49
    • 0023882238 scopus 로고
    • Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization
    • Nomura S., Wills A.J., Edwards D.R., Heath J.K., and Hogan B.L. Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J. Cell Biol. 106 (1988) 441-450
    • (1988) J. Cell Biol. , vol.106 , pp. 441-450
    • Nomura, S.1    Wills, A.J.2    Edwards, D.R.3    Heath, J.K.4    Hogan, B.L.5
  • 50
    • 0031013634 scopus 로고    scopus 로고
    • Single cell analysis of intracellular osteopontin in osteogenic cultures of fetal rat calvarial cells
    • Zohar R., Lee W., Arora P., Cheifetz S., McCulloch C., and Sodek J. Single cell analysis of intracellular osteopontin in osteogenic cultures of fetal rat calvarial cells. J. Cell. Physiol. 170 (1997) 88-100
    • (1997) J. Cell. Physiol. , vol.170 , pp. 88-100
    • Zohar, R.1    Lee, W.2    Arora, P.3    Cheifetz, S.4    McCulloch, C.5    Sodek, J.6
  • 51
    • 0034093124 scopus 로고    scopus 로고
    • Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration
    • Zohar R., Suzuki N., Suzuki K., Arora P., Glogauer M., McCulloch C.A., and Sodek J. Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J. Cell. Physiol. 184 (2000) 118-130
    • (2000) J. Cell. Physiol. , vol.184 , pp. 118-130
    • Zohar, R.1    Suzuki, N.2    Suzuki, K.3    Arora, P.4    Glogauer, M.5    McCulloch, C.A.6    Sodek, J.7
  • 52
    • 0025316785 scopus 로고
    • Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
    • Owen T.A., Aronow M., Shalhoub V., Barone L.M., Wilming L., Tassinari M.S., Kennedy M.B., Pockwinse S., Lian J.B., and Stein G.S. Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J. Cell. Physiol. 143 (1990) 420-430
    • (1990) J. Cell. Physiol. , vol.143 , pp. 420-430
    • Owen, T.A.1    Aronow, M.2    Shalhoub, V.3    Barone, L.M.4    Wilming, L.5    Tassinari, M.S.6    Kennedy, M.B.7    Pockwinse, S.8    Lian, J.B.9    Stein, G.S.10
  • 53
    • 0027321842 scopus 로고
    • Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype
    • Stein G.S., and Lian J.B. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr. Rev. 14 (1993) 424-442
    • (1993) Endocr. Rev. , vol.14 , pp. 424-442
    • Stein, G.S.1    Lian, J.B.2
  • 54
    • 0027954383 scopus 로고
    • Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture
    • Yao K.L., Todescan Jr. R., and Sodek J. Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture. J. Bone Miner. Res. 9 (1994) 231-240
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 231-240
    • Yao, K.L.1    Todescan Jr., R.2    Sodek, J.3
  • 55
    • 0030064334 scopus 로고    scopus 로고
    • Receptor-ligand interaction between CD44 and osteopontin (Eta-1)
    • Weber G.F., Ashkar S., Glimcher M.J., and Cantor H. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science 271 (1996) 509-512
    • (1996) Science , vol.271 , pp. 509-512
    • Weber, G.F.1    Ashkar, S.2    Glimcher, M.J.3    Cantor, H.4
  • 56
    • 0031613168 scopus 로고    scopus 로고
    • Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration
    • Zohar R., Cheifetz S., McCulloch C.A., and Sodek J. Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration. Eur. J. Oral Sci. 106 Suppl 1 (1998) 401-407
    • (1998) Eur. J. Oral Sci. , vol.106 , Issue.SUPPL. 1 , pp. 401-407
    • Zohar, R.1    Cheifetz, S.2    McCulloch, C.A.3    Sodek, J.4
  • 57
    • 0022580184 scopus 로고
    • Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins
    • Romberg R.W., Werness P.G., Riggs B.L., and Mann K.G. Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins. Biochemistry 25 (1986) 1176-1180
    • (1986) Biochemistry , vol.25 , pp. 1176-1180
    • Romberg, R.W.1    Werness, P.G.2    Riggs, B.L.3    Mann, K.G.4
  • 58
    • 0024372773 scopus 로고
    • Osteocalcin-hydroxyapatite interaction in the extracellular organic matrix of bone
    • Hauschka P.V., and Wians Jr. F.H. Osteocalcin-hydroxyapatite interaction in the extracellular organic matrix of bone. Anat. Rec. 224 (1989) 180-188
    • (1989) Anat. Rec. , vol.224 , pp. 180-188
    • Hauschka, P.V.1    Wians Jr., F.H.2
  • 59
    • 0033567835 scopus 로고    scopus 로고
    • Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro
    • Malaval L., Liu F., Roche P., and Aubin J.E. Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro. J. Cell. Biochem. 74 (1999) 616-627
    • (1999) J. Cell. Biochem. , vol.74 , pp. 616-627
    • Malaval, L.1    Liu, F.2    Roche, P.3    Aubin, J.E.4
  • 60
    • 0035027677 scopus 로고    scopus 로고
    • Individual osteoblasts in the developing calvaria express different gene repertoires
    • Candeliere G.A., Liu F., and Aubin J.E. Individual osteoblasts in the developing calvaria express different gene repertoires. Bone 28 (2001) 351-361
    • (2001) Bone , vol.28 , pp. 351-361
    • Candeliere, G.A.1    Liu, F.2    Aubin, J.E.3
  • 61
    • 33751534268 scopus 로고    scopus 로고
    • Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation
    • Ito S., Suzuki N., Kato S., Takahashi T., and Takagi M. Glucocorticoids induce the differentiation of a mesenchymal progenitor cell line, ROB-C26 into adipocytes and osteoblasts, but fail to induce terminal osteoblast differentiation. Bone 40 (2007) 84-92
    • (2007) Bone , vol.40 , pp. 84-92
    • Ito, S.1    Suzuki, N.2    Kato, S.3    Takahashi, T.4    Takagi, M.5
  • 62
    • 1542286116 scopus 로고    scopus 로고
    • Expression of preosteoblast markers and Cbfa-1 and Osterix gene transcripts in stromal tumour cells of giant cell tumour of bone
    • Huang L., Teng X.Y., Cheng Y.Y., Lee K.M., and Kumta S.M. Expression of preosteoblast markers and Cbfa-1 and Osterix gene transcripts in stromal tumour cells of giant cell tumour of bone. Bone 34 (2004) 393-401
    • (2004) Bone , vol.34 , pp. 393-401
    • Huang, L.1    Teng, X.Y.2    Cheng, Y.Y.3    Lee, K.M.4    Kumta, S.M.5
  • 63
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., and Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246 (1989) 1306-1309
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 64
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer B., Wizigmann-Voos S., Schnurch H., Martinez R., Moller N.P., Risau W., and Ullrich A. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72 (1993) 835-846
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6    Ullrich, A.7
  • 66
    • 0028237788 scopus 로고
    • Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts
    • Midy V., and Plouet J. Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts. Biochem. Biophys. Res. Commun. 199 (1994) 380-386
    • (1994) Biochem. Biophys. Res. Commun. , vol.199 , pp. 380-386
    • Midy, V.1    Plouet, J.2
  • 67
    • 0036166701 scopus 로고    scopus 로고
    • Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
    • Maes C., Carmeliet P., Moermans K., Stockmans I., Smets N., Collen D., Bouillon R., and Carmeliet G. Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech. Dev. 111 (2002) 61-73
    • (2002) Mech. Dev. , vol.111 , pp. 61-73
    • Maes, C.1    Carmeliet, P.2    Moermans, K.3    Stockmans, I.4    Smets, N.5    Collen, D.6    Bouillon, R.7    Carmeliet, G.8
  • 69
    • 23844506742 scopus 로고    scopus 로고
    • Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling
    • Celil A.B., Hollinger J.O., and Campbell P.G. Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling. J. Cell. Biochem. 95 (2005) 518-528
    • (2005) J. Cell. Biochem. , vol.95 , pp. 518-528
    • Celil, A.B.1    Hollinger, J.O.2    Campbell, P.G.3
  • 70
    • 33847375078 scopus 로고    scopus 로고
    • Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
    • Ge C., Xiao G., Jiang D., and Franceschi R.T. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J. Cell Biol. 176 (2007) 709-718
    • (2007) J. Cell Biol. , vol.176 , pp. 709-718
    • Ge, C.1    Xiao, G.2    Jiang, D.3    Franceschi, R.T.4
  • 71
    • 0038185348 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase is required for osteoblast differentiation
    • Hu Y., Chan E., Wang S.X., and Li B. Activation of p38 mitogen-activated protein kinase is required for osteoblast differentiation. Endocrinology 144 (2003) 2068-2074
    • (2003) Endocrinology , vol.144 , pp. 2068-2074
    • Hu, Y.1    Chan, E.2    Wang, S.X.3    Li, B.4
  • 72
    • 33947427924 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase regulates osteoblast differentiation through osterix
    • Wang X., Goh C.H., and Li B. p38 mitogen-activated protein kinase regulates osteoblast differentiation through osterix. Endocrinology 148 (2007) 1629-1637
    • (2007) Endocrinology , vol.148 , pp. 1629-1637
    • Wang, X.1    Goh, C.H.2    Li, B.3
  • 73
    • 0034254273 scopus 로고    scopus 로고
    • A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration
    • Gille H., Kowalski J., Yu L., Chen H., Pisabarro M.T., Davis-Smyth T., and Ferrara N. A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration. Embo J. 19 (2000) 4064-4073
    • (2000) Embo J. , vol.19 , pp. 4064-4073
    • Gille, H.1    Kowalski, J.2    Yu, L.3    Chen, H.4    Pisabarro, M.T.5    Davis-Smyth, T.6    Ferrara, N.7
  • 74
    • 0031957932 scopus 로고    scopus 로고
    • Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different underlying osteogenic mechanisms
    • Gorski J.P. Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different underlying osteogenic mechanisms. Crit. Rev. Oral Biol. Med. 9 (1998) 201-223
    • (1998) Crit. Rev. Oral Biol. Med. , vol.9 , pp. 201-223
    • Gorski, J.P.1
  • 75
    • 33644867417 scopus 로고    scopus 로고
    • Osteoclastogenesis in the nonadherent cell population of human bone marrow is inhibited by rhBMP-2 alone or together with rhVEGF
    • Wan C., He Q., and Li G. Osteoclastogenesis in the nonadherent cell population of human bone marrow is inhibited by rhBMP-2 alone or together with rhVEGF. J. Orthop. Res. 24 (2006) 29-36
    • (2006) J. Orthop. Res. , vol.24 , pp. 29-36
    • Wan, C.1    He, Q.2    Li, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.